Occult Hepatitis B Virus Infection and Its Risks of Cryptic Transmission in Southern Ethiopia

References

• Hollinger FB, Sood G. Occult hepatitis B virus infection: a covert operation. J Viral Hepat. 2010;17(1):1–5. doi:10.1111/j.1365-2893.2009.01245.x
   Web of Science ®Google Scholar
• Prati D, Gerosa A, Porretti L. Occult HBV infection and blood transfusion. J Hepatol. 2006;44(4):818. doi:10.1016/j.jhep.2005.12.009
   Web of Science ®Google Scholar
• Bréchot C, Thiers V, Kremsdorf D, Nalpas B, Pol S, Paterlini‐Bréchot P. Persistent hepatitis B virus infection in subjects without hepatitis B surface antigen: clinically significant or purely “occult”? Hepatology. 2001;34(1):194–203. doi:10.1053/jhep.2001.25172
   PubMed Web of Science ®Google Scholar
• Allain JP, Candotti D. Diagnostic algorithm for HBV safe transfusion. Blood Transfus. 2009;7(3):174. doi:10.2450/2008.0062-08
   Web of Science ®Google Scholar
• Lok AS, McMahon BJ. Chronic hepatitis B. Hepatology. 2007;45(2):507–539. doi:10.1002/hep.21513
   PubMed Web of Science ®Google Scholar
• Ganem D, Prince AM. Hepatitis B virus infection-natural history and clinical consequences. N Engl J Med. 2004;350(11):1118–1129. doi:10.1056/NEJMra031087
   PubMed Web of Science ®Google Scholar
• Hadziyannis SJ, Vassilopoulos D. Hepatitis B e antigen-negative chronic hepatitis B. Hepatology. 2001;34(4):617–624. doi:10.1053/jhep.2001.27834
   PubMed Web of Science ®Google Scholar
• Weber B, Melchior W, Gehrke R, Doerr HW, Berger A, Rabenau H. Hepatitis B virus markers in anti‐HBc only positive individuals. J Med Virol. 2001;64(3):312–319. doi:10.1002/jmv.1052
   Web of Science ®Google Scholar
• Grob P, Jilg W, Bornhak H, et al. Serological pattern “anti‐HBc alone”: report on a workshop. J Med Virol. 2000;62(4):450–455. doi:10.1002/1096-9071(200012)62:4<450::AID-JMV9>3.0.CO;2-Y
   Web of Science ®Google Scholar
• Gerlich WH. Medical virology of hepatitis B: how it began and where we are now. Virol J. 2013;10(1):1–25. doi:10.1186/1743-422X-10-239
   PubMed Web of Science ®Google Scholar
• Bengsch B, Chang KM. Evolution in our understanding of hepatitis B virus virology and immunology. Clin Liver Dis. 2016;20(4):629–644. doi:10.1016/j.cld.2016.06.001
   PubMed Web of Science ®Google Scholar
• Pollicino T, Raimondo G. Occult hepatitis B infection. J Hepatol. 2014;61(3):688–689. doi:10.1016/j.jhep.2014.04.036
   PubMed Web of Science ®Google Scholar
• Kang SY, Kim MH, Lee WI. The prevalence of “anti‐HBc alone” and HBV DNA detection among anti‐HBc alone in Korea. J Med Virol. 2010;82(9):1508–1514. doi:10.1002/jmv.21862
   Web of Science ®Google Scholar
• Said ZN. An overview of occult hepatitis B virus infection. World J Gastroenterol. 2011;17(15):1927. doi:10.3748/wjg.v17.i15.1927
   Web of Science ®Google Scholar
• Raffa G, Maimone S, Cargnel A, et al. Analysis of occult hepatitis B virus infection in liver tissue of HIV patients with chronic hepatitis. C. Aids. 2007;21(16):2171–2175. doi:10.1097/QAD.0b013e3282eea504
   Web of Science ®Google Scholar
• Raimondo G, Pollicino T, Cacciola I, Squadrito G. Occult hepatitis B virus infection. J Hepatol. 2007;46(1):160–170. doi:10.1016/j.jhep.2006.10.007
   PubMed Web of Science ®Google Scholar
• Hu KQ. Occult hepatitis B virus infection and its clinical implications. J Viral Hepat. 2002;9(4):243–257. doi:10.1046/j.1365-2893.2002.00344.x
   PubMed Web of Science ®Google Scholar
• El Chaar M, Candotti D, Crowther RA, Allain JP. Impact of hepatitis B virus surface protein mutations on the diagnosis of occult hepatitis B virus infection. Hepatology. 2010;52(5):1600–1610. doi:10.1002/hep.23886
   Web of Science ®Google Scholar
• Kim SM, Lee KS, Park CJ, et al. Prevalence of occult HBV infection among subjects with normal serum ALT levels in Korea. J Infect. 2007;54(2):185–191. doi:10.1016/j.jinf.2006.02.002
   PubMed Web of Science ®Google Scholar
• Nishikawa H, Osaki Y. Clinical significance of occult hepatitis B infection in progression of liver disease and carcinogenesis. J Cancer. 2013;4(6):473. doi:10.7150/jca.6609
   Web of Science ®Google Scholar
• Coppola N, Onorato L, Pisaturo M, et al. Role of occult hepatitis B virus infection in chronic hepatitis C. World J Gastroenterol. 2015;21(42):11931. doi:10.3748/wjg.v21.i42.11931
   PubMed Web of Science ®Google Scholar
• Castillo I, Rodríguez‐Iñigo E, López‐Alcorocho JM, Bartolomé J, Pardo M, Carreño V. Comparative study on the clinical and virological characteristics among patients with single occult hepatitis B virus (HBV), single occult hepatitis C virus (HCV) and occult HBV and HCV dual infection. J Med Virol. 2007;79(3):236–241. doi:10.1002/jmv.20784
   Web of Science ®Google Scholar
• Re III VL, Frank I, Gross R, et al. Prevalence, risk factors, and outcomes for occult hepatitis B virus infection among HIV-infected patients. JAIDS. 2007;44(3):315–320. doi:10.1097/QAI.0b013e31802ea499
   Google Scholar
• Mphahlele MJ, Lukhwareni A, Burnett RJ, Moropeng LM, Ngobeni JM. High risk of occult hepatitis B virus infection in HIV-positive patients from South Africa. J Clin Virol. 2006;35(1):14–20. doi:10.1016/j.jcv.2005.04.003
   PubMed Web of Science ®Google Scholar
• Dickens C, Kew MC, Purcell RH, Kramvis A. Occult hepatitis B virus infection in chacma baboons, South Africa. Emerg Infect Dis. 2013;19(4):598. doi:10.3201/eid1904.121107
   Web of Science ®Google Scholar
• Seeger C, Mason WS. Molecular biology of hepatitis B virus infection. Virology. 2015;479:672–686. doi:10.1016/j.virol.2015.02.031
   Web of Science ®Google Scholar
• Yan YP, Su HX, Ji ZH, Shao ZJ, Pu ZS. Epidemiology of hepatitis B virus infection in China: current status and challenges. J Clin Transl Hepatol. 2014;2(1):15. doi:10.14218/JCTH.2013.00030
   PubMedGoogle Scholar
• Oluyinka OO, Tong HV, Bui Tien S, et al. Occult hepatitis B virus infection in Nigerian blood donors and hepatitis B virus transmission risks. PLoS One. 2015;10(7):e0131912. doi:10.1371/journal.pone.0131912
   PubMed Web of Science ®Google Scholar
• Hollinger FB. Hepatitis B virus infection and transfusion medicine: science and the occult. Transfusion. 2008;48(5):1001–1026. doi:10.1111/j.1537-2995.2008.01701.x
   Web of Science ®Google Scholar
• Coppola N, Sagnelli C, Pisaturo M, et al. Clinical and virological characteristics associated with severe acute hepatitis B. Clin Microbiol Infect. 2014;20(12):O991–7. doi:10.1111/1469-0691.12720
   Web of Science ®Google Scholar
• Tsubota A, Kumada H, Takaki K, et al. Deletions in the hepatitis B virus core gene may influence the clinical outcome in hepatitis B e antigen-positive asymptomatic healthy carriers. J Med Virol. 1998;56(4):287–293. doi:10.1002/(SICI)1096-9071(199812)56:4<287::AID-JMV1>3.0.CO;2-P
   Web of Science ®Google Scholar
• Shastry S, Bhat SS. Prevention of post-transfusion hepatitis by screening of antibody to hepatitis B core antigen in healthy blood donors. Mediterr J Hematol Infect Dis. 2011;3(1):e2011062. doi:10.4084/mjhid.2011.062
   Google Scholar
• Allain JP, Mihaljevic I, Gonzalez‐Fraile MI, et al. Infectivity of blood products from donors with occult hepatitis B virus infection. Transfusion J. 2013;53(7):1405–1415. doi:10.1111/trf.12096
   Web of Science ®Google Scholar
• Squadrito G, Cacciola I, Alibrandi A, Pollicino T, Raimondo G. Impact of occult hepatitis B virus infection on the outcome of chronic hepatitis C. J Hepatol. 2013;59(4):696–700. doi:10.1016/j.jhep.2013.05.043
   PubMed Web of Science ®Google Scholar
• Lall S, Choudhary MC, Mahajan S, Kumar G, Gupta E. Performance evaluation of TRUPCR® HBV Real-time PCR assay for Hepatitis B virus DNA quantification in clinical samples: report from a tertiary care liver centre. Virusdisease. 2019;30(2):186–192. doi:10.1007/s13337-018-0502-0
   Google Scholar
• Belyhun Y, Maier M, Mulu A, Diro E, Liebert UG. Hepatitis viruses in Ethiopia: a systematic review and meta-analysis. BMC Infect Dis. 2016;16(1):1–4. doi:10.1186/s12879-016-2090-1
   PubMed Web of Science ®Google Scholar
• Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat. 2004;11(2):97–107. doi:10.1046/j.1365-2893.2003.00487.x
   PubMed Web of Science ®Google Scholar
• Spearman CW, Afihene M, Ally R, et al. Hepatitis B in sub-Saharan Africa: strategies to achieve the 2030 elimination targets. Lancet Gastroenterol Hepatol. 2017;2(12):900–909. doi:10.1016/S2468-1253(17)30295-9
   PubMed Web of Science ®Google Scholar
• Al-Sadi AM, Al-Oweisi FA, Edwards SG, Al-Nadabi H, Al-Fahdi AM. Genetic analysis reveals diversity and genetic relationship among Trichoderma isolates from potting media, cultivated soil and uncultivated soil. BMC Microbiol. 2015;15(1):1. doi:10.1186/s12866-015-0483-8
   PubMed Web of Science ®Google Scholar
• Ochwoto M, Kimotho JH, Oyugi J, et al. Hepatitis B infection is highly prevalent among patients presenting with jaundice in Kenya. BMC Infect Dis. 2016;16(1):1–4. doi:10.1186/s12879-016-1409-2
   PubMed Web of Science ®Google Scholar
• Talla C, Itanyi IU, Tsuyuki K, et al. Hepatitis B infection and risk factors among pregnant women and their male partners in the Baby Shower Programme in Nigeria: a cross‐sectional study. Trop Med Int Health. 2021;26(3):316–326. doi:10.1111/tmi.13531
   Web of Science ®Google Scholar
• Ayana DA, Mulu A, Mihret A, Seyoum B, Aseffa A, Howe R. Occult Hepatitis B virus infection among HIV negative and positive isolated anti-HBc individuals in eastern Ethiopia. Sci Rep. 2020;10(1):1–9. doi:10.1038/s41598-020-79392-x
   Web of Science ®Google Scholar
• Patel NH, Meier-Stephenson V, Genetu M, et al. Prevalence and genetic variability of occult hepatitis B virus in a human immunodeficiency virus positive patient cohort in Gondar, Ethiopia. PLoS One. 2020;15(11):e0242577. doi:10.1371/journal.pone.0242577
   PubMed Web of Science ®Google Scholar
• Meier-Stephenson V, Deressa T, Genetu M, et al. Prevalence and molecular characterization of occult hepatitis B virus in pregnant women from Gondar, Ethiopia. Can Liver J. 2020;3(4):323–333. doi:10.3138/canlivj-2019-0031
   Google Scholar
• N’Dri-Yoman T, Anglaret X, Messou E, et al. Short communication Occult HBV infection in untreated HIV-infected adults in Côte d’Ivoire. Antivir Ther. 2010;15:1029–1034. doi:10.3851/IMP1641
   PubMed Web of Science ®Google Scholar
• Mudawi H, Hussein W, Mukhtar M, et al. Overt and occult hepatitis B virus infection in adult Sudanese HIV patients. Int J Infect Dis. 2014;29:65–70. doi:10.1016/j.ijid.2014.07.004
   PubMed Web of Science ®Google Scholar
• Jepkemei KB, Ochwoto M, Swidinsky K, et al. Characterization of occult hepatitis B in high-risk populations in Kenya. PLoS One. 2020;15(5):e0233727. doi:10.1371/journal.pone.0233727
   Web of Science ®Google Scholar
• Nna E, Mbamalu C, Ekejindu I. Occult hepatitis B viral infection among blood donors in South–Eastern Nigeria. Pathog Glob Health. 2014;108(5):223–228. doi:10.1179/2047773214Y.0000000144
   PubMed Web of Science ®Google Scholar
• Salpini R, Fokam J, Ceccarelli L, et al. High burden of HBV-infection and atypical HBV strains among HIV-infected Cameroonians. Curr HIV Res. 2016;14(2):165–171. doi:10.2174/1570162X13666150930114742
   Web of Science ®Google Scholar
• Firnhaber C, Chen CY, Evans D, et al. Prevalence of hepatitis B virus (HBV) co-infection in HBV serologically-negative South African HIV patients and retrospective evaluation of the clinical course of mono-and co-infection. Int J Infect Dis. 2012;16(4):e268–72. doi:10.1016/j.ijid.2011.12.007
   Web of Science ®Google Scholar
• El-Zaatari M, Kazma H, Naboulsi-Majzoub M, et al. Hepatitis B virus DNA in serum of ‘anti-HBc only’-positive healthy Lebanese blood donors: significance and possible implications. J Hosp Infect. 2007;66(3):278–282. doi:10.1016/j.jhin.2007.04.010
   Web of Science ®Google Scholar
• Filippini P, Coppola N, Pisapia R, et al. Impact of occult hepatitis B virus infection in HIV patients naive for antiretroviral therapy. Aids. 2006;20(9):1253–1260. doi:10.1097/01.aids.0000232232.41877.2a
   PubMed Web of Science ®Google Scholar
• Urbani S, Fagnoni F, Missale G, Franchini M. The role of anti-core antibody response in the detection of occult hepatitis B virus infection. Clin Chem Labor Med. 2010;48(1):23–29. doi:10.1515/CCLM.2010.002
   Web of Science ®Google Scholar
• Mühlbacher A, Zdunek D, Melchior W, Michl U. Is infective blood donation missed without screening for antibody to hepatitis B core antigen and/or hepatitis B virus DNA? Vox Sang. 2001;81(2):139. doi:10.1046/j.1423-0410.2001.00086.x
   Web of Science ®Google Scholar
• Torbenson M, Thomas DL. Occult hepatitis B. Lancet Infect Dis. 2002;2(8):479–486. doi:10.1016/S1473-3099(02)00345-6
   PubMed Web of Science ®Google Scholar
• Sagnelli E, Stroffolini T, Mele A, Imparato M, Almasio PL. New features of an old disease-approaching the universal prevalence of hepatitis B e antigen-negative cases and the eradication of hepatitis D infection. Clin Infect Dis. 2008;46(1):110–113. doi:10.1086/524074
   PubMed Web of Science ®Google Scholar
• Ayana DA, Mulu A, Mihret A, Seyoum B, Aseffa A, Howe R. Hepatitis B virus seromarkers among HIV infected adults on ART: an unmet need for HBV screening in eastern Ethiopia. PLoS One. 2019;14(12):e0226922. doi:10.1371/journal.pone.0226922
   PubMed Web of Science ®Google Scholar
• Abebe D, Debella A, Dejene A, et al. Khat chewing habit as a possible risk behaviour for HIV infection: a case-control study. Ethiop J Health Dev. 2005;19(3):174–181.
   Google Scholar
• Soboka M, Tesfaye M, Feyissa GT, Hanlon C. Khat use in people living with HIV: a facility-based cross-sectional survey from South West Ethiopia. BMC Psychiatr. 2015;15(1):1–7. doi:10.1186/s12888-015-0446-5
   PubMed Web of Science ®Google Scholar
• Tilahun M, Ayele G. Factors associated with Khat use among youths visiting HIV testing and counseling centers in Gamo Gofa, Southern Ethiopia. BMC Public Health. 2013;13(1):1–6. doi:10.1186/1471-2458-13-1199
   Web of Science ®Google Scholar
• Berhanu D, Diener-West M, Ruff A, Davis WW, Celentano DD, Go VF. Associations between Khat use and HIV risk and status among voluntary counseling and testing center clients in Addis Ababa, Ethiopia. J Addict Med. 2017;11(4):320. doi:10.1097/ADM.0000000000000304
   PubMed Web of Science ®Google Scholar
• Nwadigwe CE. ‘I want to be a star’: doping technology and the incidence of performance-enhancing drugs among actors in Nigeria. Afri Sociol Rev. 2008;12(2):144–154.
   Google Scholar
• Chama D, Ahmed Y, Baboo KS, Halwindi H, Mulenga J. Transfusion transmissible infections among voluntary blood donors at the university teaching hospital, Lusaka, Zambia. Med J Zambia. 2015;42(3):90–95.
   Google Scholar
• Fasola FA, Fadimu PA, Akpan VO. A seven year review of the Seroprevalence of transfusion transmitted infections in a hospital based blood bank in Ibadan, Nigeria. Clin Med Res. 2017;6(1):1–8. doi:10.11648/j.cmr.20170601.11
   Google Scholar
• Loua A, Diallo MB, Magassouba FB, Camara M, Bah MA, Cisse A. Seroprevalence of hepatitis B in blood donors in Guinea. Medecine Tropicale. 2005;65(4):396–397.
   Google Scholar