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Infection and Drug Resistance Volume 15, 2022 - Issue
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CASE REPORT

Severe Intravascular Hemolysis from Clostridium perfringens Septicemia in a Neonate with Necrotizing Enterocolitis in China: A Case Report

Zhiqi Li1 Department of Neonatology, ChangNing Maternity and Infant Health Institute, Shanghai, 200051, People’s Republic of China
,
Chongbing Yan2 Department of Neonatology, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai, 200062, People’s Republic of China
,
Xiaohui Gong2 Department of Neonatology, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai, 200062, People’s Republic of China
&
Junfang Wang2 Department of Neonatology, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai, 200062, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3328-978X
ORCID Icon
Pages 1461-1465 | Published online: 02 Apr 2022

References

  • Sim K, Shaw AG, Randell P, et al. Dysbiosis anticipating necrotizing enterocolitis in very premature infants. Clin Infect Dis. 2015;60(3):389–397. doi:10.1093/cid/ciu822
  • van Bunderen CC, Bomers MK, Wesdorp E, Peerbooms P, Veenstra J. Clostridium perfringens septicaemia with massive intravascular haemolysis: a case report and review of the literature. Neth J Med. 2010;68(9):343–346.
  • Shaw AG, Cornwell E, Sim K, et al. Dynamics of toxigenic Clostridium perfringens colonisation in a cohort of prematurely born neonatal infants. BMC Pediatr. 2020;20(1):75. doi:10.1186/s12887-020-1976-7
  • Law ST, Lee MK. A middle-aged lady with a pyogenic liver abscess caused by Clostridium perfringens. World J Hepatol. 2012;4(8):252–255. doi:10.4254/wjh.v4.i8.252
  • Suzaki A, Ohtani K, Komine-Aizawa S, Matsumoto A, Kamiya S, Hayakawa S. Pathogenic characterization of Clostridium perfringens strains isolated from patients with massive intravascular hemolysis. Front Microbiol. 2021;12:713509. doi:10.3389/fmicb.2021.713509
  • Rood JI, Adams V, Lacey J, et al. Expansion of the Clostridium perfringens toxin-based typing scheme. Anaerobe. 2018;53:5–10. doi:10.1016/j.anaerobe.2018.04.011
  • Petit L, Gibert M, Popoff MR. Clostridium perfringens: toxinotype and genotype. Trends Microbiol. 1999;7(3):104–110. doi:10.1016/S0966-842X(98)01430-9
  • Kapoor JR, Monteiro B, Tanoue L, Siegel MD. Massive intravascular hemolysis and a rapidly fatal outcome. Chest. 2007;132(6):2016–2019. doi:10.1378/chest.07-0853
  • Simon TG, Bradley J, Jones A, Carino G. Massive intravascular hemolysis from Clostridium perfringens septicemia: a review. J Intensive Care Med. 2014;29(6):327–333. doi:10.1177/0885066613498043
  • Moh-Klaren J, Bodivit G, Jugie M, et al. Severe hemolysis after plasma transfusion in a neonate with necrotizing enterocolitis, Clostridium perfringens infection, and red blood cell T-polyagglutination. Transfusion. 2017;57(11):2571–2577. doi:10.1111/trf.14196
  • Heuck AP, Savva CG, Holzenburg A, Johnson AE. Conformational changes that effect oligomerization and initiate pore formation are triggered throughout perfringolysin O upon binding to cholesterol. J Biol Chem. 2007;282(31):22629–22637. doi:10.1074/jbc.M703207200
  • Pedersen PV, Hansen FH, Halveg AB, Christiansen ED, Justesen T, Høgh P. Necrotising enterocolitis of the newborn–is it gas-gangrene of the bowel. Lancet. 1976;308(7988):715–716. doi:10.1016/S0140-6736(76)90009-X
  • Neu J, Walker WA. Necrotizing enterocolitis. N Engl J Med. 2011;364(3):255–264. doi:10.1056/NEJMra1005408
  • Liu F, Xue S, Zhang Y, et al. Clostridium perfringens sepsis in three patients with acute leukemia and review of the literature. Int J Hematol. 2021;113(4):508–517. doi:10.1007/s12185-020-03060-z
  • Schmoch T, Westhoff JH, Decker SO, et al. Next-generation sequencing diagnostics of bacteremia in pediatric sepsis. Medicine. 2021;100(25):e26403. doi:10.1097/MD.0000000000026403

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