Clinical Value of Metagenomics Next-Generation Sequencing in Bronchoalveolar Lavage Fluid for Patients with Severe Hospital-Acquired Pneumonia: A Nested Case–Control Study

References

• Melsen WG, Rovers MM, Groenwold RH, et al. Attributable mortality of ventilator-associated pneumonia: a metaanalysis of individual patient data from randomized prevention studies. Lancet Infect Dis. 2013;13(8):665–671. doi:10.1016/S1473-3099(13)70081-1
   PubMed Web of Science ®Google Scholar
• Koulenti D, Tsigou E, Rello J. Nosocomial pneumonia in 27 ICUs in Europe: perspectives from the EU-VAP/CAP study. Eur J Clin Microbiol Infect Dis. 2017;36(11):1999–2006. doi:10.1007/s10096-016-2703-z
   PubMed Web of Science ®Google Scholar
• Lopez-de-andres A, Albaladejo-Vicente R, de Miguel-diez J, et al. Incidence and outcomes of hospitalization for community-acquired, ventilator-associated and non-ventilator hospital-acquired pneumonias in patients with type 2 diabetes mellitus in Spain. BMJ Open Diabetes Res Care. 2020;8(1):e001447. doi:10.1136/bmjdrc-2020-001447
   PubMed Web of Science ®Google Scholar
• Cantral DE, Tape TG, Reed EC, et al. Quantitative culture of bronchoalveolar lavage fluid for the diagnosis of bacterial pneumonia. Am J Med. 1993;95(6):601–607. doi:10.1016/0002-9343(93)90356-t
   Web of Science ®Google Scholar
• Kang JY, Kim SJ. Reasons for low bacterial yields from quantitative cultures of bronchoalveolar lavage fluid. Korean J Intern Med. 2012;27(2):149–150. doi:10.3904/kjim.2012.27.2.149
   Web of Science ®Google Scholar
• Baughman RP. Protected-specimen brush technique in the diagnosis of ventilator-associated pneumonia. Chest. 2000;117(4Suppl 2):203S–206S. doi:10.1378/chest.117.4_suppl_2.203s
   Web of Science ®Google Scholar
• Mondi MM, Chang MC, Bowton DL, et al. Prospective comparison of bronchoalveolar lavage and quantitative deep tracheal aspirate in the diagnosis of ventilator associated pneumonia. J Trauma. 2005;59(4):891–895; discussion 895–896. doi:10.1097/01.ta.0000188011.58790.e9
   Google Scholar
• Johansson N, Kalin M, Tiveljung-Lindell A, et al. Etiology of community-acquired pneumonia: increased microbiological yield with new diagnostic methods. Clin Infect Dis. 2010;50(2):202–209. doi:10.1086/648678
   PubMed Web of Science ®Google Scholar
• Tetenta S, Metersky ML. Tracheal aspirate Gram stain has limited sensitivity and specificity for detecting Staphylococcus aureus. Respirology. 2011;16:86–89. doi:10.1111/j.1440-1843.2010.01855.x
   Web of Science ®Google Scholar
• Wilson MR, Naccache SN, Samayoa E, et al. Actionable diagnosis of neuroleptospirosis by next-generation sequencing. N Engl J Med. 2014;370(25):2408–2417. doi:10.1056/NEJMoa1401268
   PubMed Web of Science ®Google Scholar
• Guo LY, Feng WY, Guo X, et al. The advantages of next-generation sequencing technology in the detection of different sources of abscess. J Infect. 2019;78(1):75–86. doi:10.1016/j.jinf.2018.08.002
   Web of Science ®Google Scholar
• Liu P, Weng X, Zhou J, et al. Next generation sequencing based pathogen analysis in a patient with neurocysticercosis: a case report. BMC Infect. 2018;18(1):113. doi:10.1186/s12879-018-3015-y
   PubMed Web of Science ®Google Scholar
• Fang X, Mei Q, Yang T, et al. Diagnostic value of metagenomic next-generation sequencing for the detection of pathogens in bronchoalveolar lavage fluid in ventilator-associated pneumonia patients. Front Microbiol. 2020;11:599756. doi:10.3389/fmicb.2020.599756
   PubMed Web of Science ®Google Scholar
• Torres A, Niederman MS, Chastre J. International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia. Eur Respir J. 2017;50(3):1700582. doi:10.1183/13993003.00582-2017
   PubMed Web of Science ®Google Scholar
• Kalil AC, Metersky ML, Klompas M, et al. Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clin Infect Dis. 2016;63(5):e61–e111. doi:10.1093/cid/ciw353
   PubMed Web of Science ®Google Scholar
• Meyer KC, Raghu G, Baughman RP, et al. An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease. Am J Respir Crit Care Med. 2012;185:1004–1014. doi:10.1164/rccm.201202-0320ST
   PubMed Web of Science ®Google Scholar
• American Thoracic Society; Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med. 2005;171(4):388–416. doi:10.1164/rccm.200405-644ST
   PubMed Web of Science ®Google Scholar
• Osterrieder N, Wallaschek N, Kaufer BB. Herpesvirus genome integration into telomeric repeats of host cell chromosomes. Annu Rev Virol. 2014;1(1):215–235. doi:10.1146/annurev-virology-031413-085422
   PubMed Web of Science ®Google Scholar
• Luyt CE, Bréchot N, Chastre J. What role do viruses play in nosocomial pneumonia? Curr Opin Infect Dis. 2014;27(2):194–199. doi:10.1097/qco.0000000000000049
   Web of Science ®Google Scholar
• Luyt CE, Combes A, Deback C, et al. Herpes simplex virus lung infection in patients undergoing prolonged mechanical ventilation. Am J Respir Crit Care Med. 2007;175(9):935–942. doi:10.1164/rccm.200609-1322OC
   PubMed Web of Science ®Google Scholar
• Li H, Gao H, Meng H, et al. Detection of pulmonary infectious pathogens from lung biopsy tissues by metagenomic next-generation sequencing. Front Cell Infect Microbiol. 2018;8:205. doi:10.3389/fcimb.2018.00205
   PubMed Web of Science ®Google Scholar
• Miao Q, Ma Y, Wang Q, et al. Microbiological diagnostic performance of metagenomic next-generation sequencing when applied to clinical practice. Clin Infect Dis. 2018;67(suppl_2):S231–S240. doi:10.1093/cid/ciy693
   PubMed Web of Science ®Google Scholar
• Xie Y, Du J, Jin W. Next generation sequencing for diagnosis of severe pneumonia: China, 2010–2018. J Infect. 2019;78(2):158–169. doi:10.1016/j.jinf.2018.09.004
   PubMed Web of Science ®Google Scholar
• Kollef MH, Shorr A, Tabak YP, et al. Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia. Chest. 2005;128(6):3854–3862. doi:10.1378/chest.128.6.3854
   PubMed Web of Science ®Google Scholar
• Corrado RE, Lee D, Lucero DE, et al. Burden of adult community-acquired, health-care-associated, hospital-acquired, and ventilator-associated pneumonia: New York City, 2010 to 2014. Chest. 2017;152(5):930–942. doi:10.1016/j.chest.2017.04.162
   PubMed Web of Science ®Google Scholar