179
Views
1
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Mortality Risk Factors and Prognostic Analysis of Patients with Multi-Drug Resistant Enterobacterales Infection

, , , , , , , , & show all
Pages 3225-3237 | Published online: 20 Jun 2022

References

  • Moghnieh R, Estaitieh N, Mugharbil A, et al. Third generation cephalosporin resistant Enterobacteriaceae and multidrug resistant gram-negative bacteria causing bacteremia in febrile neutropenia adult cancer patients in Lebanon, broad spectrum antibiotics use as a major risk factor, and correlation with poor prognosis. Front Cell Infect Microbiol. 2015;5:11. doi:10.3389/fcimb.2015.00011
  • Villafuerte D, Aliberti S, Soni NJ, et al. Prevalence and risk factors for Enterobacteriaceae in patients hospitalized with community-acquired pneumonia. Respirology. 2020;25(5):543–551. doi:10.1111/resp.13663
  • Liu J, Zhang L, Pan J, et al. Risk factors and molecular epidemiology of complicated intra-abdominal infections with carbapenem-resistant Enterobacteriaceae: a multicenter study in China. J Infect Dis. 2020;221(Suppl 2):S156–S163. doi:10.1093/infdis/jiz574
  • Manandhar S, Zellweger RM, Maharjan N, et al. A high prevalence of multi-drug resistant Gram-negative bacilli in a Nepali tertiary care hospital and associated widespread distribution of Extended-Spectrum Beta-Lactamase (ESBL) and carbapenemase-encoding genes. Ann Clin Microbiol Antimicrob. 2020;19(1):48. doi:10.1186/s12941-020-00390-y
  • Blin C, Passet V, Touchon M, Rocha E, Brisse S. Metabolic diversity of the emerging pathogenic lineages of Klebsiella pneumoniae. Environ Microbiol. 2017;19(5):1881–1898. doi:10.1111/1462-2920.13689
  • Liu Z, Gu Y, Li X, et al. Identification and characterization of NDM-1-producing Hypervirulent (Hypermucoviscous) Klebsiella pneumoniae in China. Ann Lab Med. 2019;39(2):167. doi:10.3343/alm.2019.39.2.167
  • Doi Y, Bonomo RA, Hooper DC, et al. Gram-negative bacterial infections: research priorities, accomplishments, and future directions of the antibacterial resistance leadership group. Clin Infect Dis. 2017;64(suppl_1):S30–S35. doi:10.1093/cid/ciw829
  • Saliba R, Ghelfenstein-Ferreira T, Lomont A, et al. Risk factors for the environmental spread of different multidrug-resistant organisms: a prospective cohort study. J Hosp Infect. 2021;111:155–161. doi:10.1016/j.jhin.2021.01.029
  • Trecarichi EM, Tumbarello M. Antimicrobial-resistant Gram-negative bacteria in febrile neutropenic patients with cancer: current epidemiology and clinical impact. Curr Opin Infect Dis. 2014;27(2):200–210. doi:10.1097/QCO.0000000000000038
  • Reynoso A, Munson E. Surveillance of Wisconsin organisms for trends in antimicrobial resistance and epidemiology (SWOTARE): 2018–2019 report on Enterobacter cloacae and Klebsiella pneumoniae clinical isolates. Clin Med Res. 2021;19(3):123–131. doi:10.3121/cmr.2021.1588
  • de Oliveira Santos JV, da Costa Junior SD, de Fátima Ramos Dos Santos Medeiros SM, et al. Panorama of bacterial infections caused by epidemic resistant strains. Curr Microbiol. 2022;79(6):175. doi:10.1007/s00284-022-02875-9
  • Iabadene H, Messai Y, Ammari H, et al. Prevalence of plasmid-mediated AmpC beta-lactamases among Enterobacteriaceae in Algiers hospitals. Int J Antimicrob Agents. 2009;34(4):340–342. doi:10.1016/j.ijantimicag.2009.05.011
  • Naas T, Bentchouala C, Cuzon G, et al. Outbreak of Salmonella enterica serotype infantis producing ArmA 16S RNA methylase and CTX-M-15 extended-spectrum beta-lactamase in a neonatology ward in Constantine, Algeria. Int J Antimicrob Agents. 2011;38(2):135–139. doi:10.1016/j.ijantimicag.2011.04.012
  • Mohsin M, Hassan B, Khan AU, Ali A, Swedberg G, Hasan B. Genomic characterization of high-risk Escherichia coli and Enterobacter hormaechei clones recovered from a single tertiary-care hospital in Pakistan. J Appl Microbiol. 2022;132(5):3907–3914. doi:10.1111/jam.15482
  • Biset S, Moges F, Endalamaw D, Eshetie S. Multi-drug resistant and extended-spectrum beta-lactamases producing bacterial uropathogens among pregnant women in Northwest Ethiopia. Ann Clin Microbiol Antimicrob. 2020;19(1):25. doi:10.1186/s12941-020-00365-z
  • Mathers AJ, Peirano G, Pitout JDD. The role of epidemic resistance plasmids and international high-risk clones in the spread of multidrug-resistant Enterobacteriaceae. Clin Microbiol Rev. 2015;28(3):565–591. doi:10.1128/CMR.00116-14
  • Cejas D, Elena A, Guevara Nunez D, et al. Changing epidemiology of KPC-producing Klebsiella pneumoniae in Argentina: emergence of hypermucoviscous ST25 and high-risk clone ST307. J Glob Antimicrob Resist. 2019;18:238–242. doi:10.1016/j.jgar.2019.06.005
  • Taggar G, Attiq Rheman M, Boerlin P, Diarra MS. Molecular epidemiology of carbapenemases in enterobacteriales from humans, animals, food and the environment. Antibiotics. 2020;9(10). doi:10.3390/antibiotics9100693
  • Evans BA, Amyes SG. OXA beta-lactamases. Clin Microbiol Rev. 2014;27(2):241–263. doi:10.1128/CMR.00117-13
  • Ngoi ST, Chong CW, Ponnampalavanar SSS, et al. Genetic mechanisms and correlated risk factors of antimicrobial-resistant ESKAPEE pathogens isolated in a tertiary hospital in Malaysia. Antimicrob Resist Infect Control. 2021;10(1):70. doi:10.1186/s13756-021-00936-5
  • Voor AF, Mourik K, Beishuizen B, et al. Acquisition of multidrug-resistant Enterobacterales during international travel: a systematic review of clinical and microbiological characteristics and meta-analyses of risk factors. Antimicrob Resist Infect Control. 2020;9(1):71. doi:10.1186/s13756-020-00733-6
  • Kajova M, Khawaja T, Kangas J, Makinen H, Kantele A. Import of multidrug-resistant bacteria from abroad through interhospital transfers, Finland, 2010–2019. Euro Surveill. 2021;26(39). doi:10.2807/1560-7917.ES.2021.26.39.2001360
  • Woerther PL, Andremont A, Kantele A. Travel-acquired ESBL-producing Enterobacteriaceae: impact of colonization at individual and community level. J Travel Med. 2017;24(suppl_1):S29–S34. doi:10.1093/jtm/taw101
  • Josseaume J, Verner L, Brady WJ, Duchateau FX. Multidrug-resistant bacteria among patients treated in foreign hospitals: management considerations during medical repatriation. J Travel Med. 2013;20(1):22–28. doi:10.1111/j.1708-8305.2012.00668.x
  • Angue M, Allou N, Belmonte O, et al. Risk factors for colonization with multidrug-resistant bacteria among patients admitted to the intensive care unit after returning from abroad. J Travel Med. 2015;22(5):300–305. doi:10.1111/jtm.12220
  • Baron SA, Cassir N, Hamel M, et al. Risk factors for acquisition of colistin-resistant Klebsiella pneumoniae and expansion of a colistin-resistant ST307 epidemic clone in hospitals in Marseille, France, 2014 to 2017. Euro Surveill. 2021;26(21). doi:10.2807/1560-7917.ES.2021.26.21.2000022
  • Wu C, Zheng L, Yao J. Analysis of risk factors and mortality of patients with carbapenem-resistant Klebsiella pneumoniae infection. Infect Drug Resist. 2022;15:2383–2391. doi:10.2147/IDR.S362723
  • Zheng G, Shi Y, Cao Y, et al. Clinical feature, therapy, antimicrobial resistance gene distribution, and outcome of nosocomial meningitis induced by multidrug-resistant Enterobacteriaceae-a longitudinal cohort study from two neurosurgical centers in Northern China. Front Cell Infect Microbiol. 2022;12:839257. doi:10.3389/fcimb.2022.839257
  • Chen D, Zhang Y, Wu J, et al. Analysis of hypervirulent Klebsiella pneumoniae and classic Klebsiella pneumoniae infections in a Chinese hospital. J Appl Microbiol. 2022;132(5):3883–3890. doi:10.1111/jam.15476
  • CaLS I. Performance Standards for Antimicrobial Susceptibility Testing. Wayne, PA: Clinical and Laboratory Standards Institute; 2021.
  • Renk H, Stoll L, Neunhoeffer F, et al. Suspicion of respiratory tract infection with multidrug-resistant Enterobacteriaceae: epidemiology and risk factors from a paediatric intensive care unit. BMC Infect Dis. 2017;17(1):163. doi:10.1186/s12879-017-2251-x
  • Pouch SM, Patel G; Practice ASTIDCo. Multidrug-resistant gram-negative bacterial infections in solid organ transplant recipients-guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant. 2019;33(9):e13594. doi:10.1111/ctr.13594
  • Wang Q, Zhang Y, Yao X, et al. Risk factors and clinical outcomes for carbapenem-resistant Enterobacteriaceae nosocomial infections. Eur J Clin Microbiol Infect Dis. 2016;35(10):1679–1689. doi:10.1007/s10096-016-2710-0
  • Williams PCM, Bartlett AW, Palasanthiran P, Armstrong B, McMullan BJ. Successful treatment of invasive carbapenemase-producing Enterobacteriaceae infections in children using carbapenem-aminoglycoside combination therapy: a case series. Infect Dis Health. 2020;25(4):314–318. doi:10.1016/j.idh.2020.06.002
  • Li Q, Zhu J, Kang J. Emergence of NDM-5-producing carbapenem-resistant Klebsiella pneumoniae and SIM-producing hypervirulent Klebsiella pneumoniae isolated from aseptic body fluid in a large tertiary hospital, 2017–2018: genetic traits of blaNDM-like and blaSIM-like genes as determined by NGS. Infect Drug Resist. 2020.
  • Paczosa MK, Mecsas J. Klebsiella pneumoniae: going on the offense with a strong defense. Microbiol Mol Biol Rev. 2016;80(3):629–661. doi:10.1128/MMBR.00078-15
  • Ruppe E, Andremont A, Armand-Lefevre L. Digestive tract colonization by multidrug-resistant Enterobacteriaceae in travellers: an update. Travel Med Infect Dis. 2018;21:28–35. doi:10.1016/j.tmaid.2017.11.007
  • Daikos GL, Markogiannakis A. Carbapenemase-producing Klebsiella pneumoniae: (when) might we still consider treating with carbapenems? Clin Microbiol Infect. 2011;17(8).
  • Patel TS, Nagel JL, Doern GV. Clinical outcomes of Enterobacteriaceae infections stratified by carbapenem MICs. J Clin Microbiol. 2015;53(1):201–205. doi:10.1128/JCM.03057-14
  • Navon-Venezia S, Kondratyeva K, Carattoli A. Klebsiella pneumoniae: a major worldwide source and shuttle for antibiotic resistance. FEMS Microbiol Rev. 2017;41(3):252–275. doi:10.1093/femsre/fux013
  • Tooke C, Hinchliffe P, Bragginton E, et al. β-Lactamases and β-Lactamase inhibitors in the 21st century. J Mol Biol. 2019;431(18):3472–3500. doi:10.1016/j.jmb.2019.04.002
  • Rapp R, Urban C. Klebsiella pneumoniae carbapenemases in Enterobacteriaceae: history, evolution, and microbiology concerns. Pharmacotherapy. 2012;32(5):399–407. doi:10.1002/j.1875-9114.2012.01035.x
  • Wendt C, Baum H, Kaase M. Hygienemaßnahmen bei Infektionen oder Besiedlung mit multiresistenten gramnegativen bakteriellen Erregern[Hygienic treatment of bacteria carrying multidrug-resistant bacteria]. Slides. 2017;55:18–20.