Potential Predictive Value of miR-125b-5p, miR-155-5p and Their Target Genes in the Course of COVID-19

References

• Wu F, Zhao S, Yu B, et al. A new coronavirus associated with human respiratory disease in China. Nature. 2020;579(7798):265–269. doi:10.1038/s41586-020-2008-3
   PubMed Web of Science ®Google Scholar
• World Health Organization. Coronavirus disease (COVID-19) outbreak situation; 2021. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019. Accessed September 1, 2021.
   Google Scholar
• Pan Y, Li X, Yang G, et al. Serological immunochromatographic approach in diagnosis with SARS-CoV-2 infected COVID-19 patients. J Infect. 2020;81(1):e28–e32. doi:10.1016/j.jinf.2020.03.051
   PubMed Web of Science ®Google Scholar
• Xu L, Cai Y, Chen X, Zhu Y, Cai J. Circulating MiR-1290 as a potential diagnostic and disease monitoring biomarker of human gastrointestinal tumors. BMC Cancer. 2021;21(1):989. doi:10.1186/s12885-021-08729-0
   Web of Science ®Google Scholar
• Feng RM, Zong YN, Cao SM, Xu RH. Current cancer situation in China: good or bad news from the 2018 Global Cancer Statistics? Cancer Commun. 2019;39(1):22. doi:10.1186/s40880-019-0368-6
   PubMed Web of Science ®Google Scholar
• Liu Z, Wang J, Ge Y, et al. SARS-CoV-2 encoded microRNAs are involved in the process of virus infection and host immune response. J Biomed Res. 2021;35(3):216–227. doi:10.7555/JBR.35.20200154
   Web of Science ®Google Scholar
• Houshmandfar S, Saeedi-Boroujeni A, Rashno M, Khodadadi A, Mahmoudian-Sani MR. miRNA-223 as a regulator of inflammation and NLRP3 inflammasome, the main fragments in the puzzle of immunopathogenesis of different inflammatory diseases and COVID-19. Naunyn Schmiedebergs Arch Pharmacol. 2021;394(11):2187–2195. doi:10.1007/s00210-021-02163-6
   PubMed Web of Science ®Google Scholar
• Visacri MB, Nicoletti AS, Pincinato EC, et al. Role of miRNAs as biomarkers of COVID-19: a scoping review of the status and future directions for research in this field. Biomark Med. 2021;15(18):1785–1795. doi:10.2217/bmm-2021-0348
   Web of Science ®Google Scholar
• Li CX, Chen J, Lv SK, Li JH, Li LL, Hu X. Whole-transcriptome RNA sequencing reveals significant differentially expressed mRNAs, miRNAs, and lncRNAs and related regulating biological pathways in the peripheral blood of COVID-19 patients. Mediators Inflamm. 2021;2021:6635925. doi:10.1155/2021/6635925
   Web of Science ®Google Scholar
• Gonzalo-Calvo D, Benitez ID, Pinilla L, et al. Circulating microRNA profiles predict the severity of COVID-19 in hospitalized patients. Transl Res. 2021;236:147–159.
   PubMed Web of Science ®Google Scholar
• Keikha R, Hashemi-Shahri SM, Jebali A. The relative expression of miR-31, miR-29, miR-126, and miR-17 and their mRNA targets in the serum of COVID-19 patients with different grades during hospitalization. Eur J Med Res. 2021;26(1):75. doi:10.1186/s40001-021-00544-4
   Web of Science ®Google Scholar
• Keikha R, Hashemi-Shahri SM, Jebali A. [The miRNA neuroinflammatory biomarkers in COVID-19 patients with different severity of illness]. Neurologia. 2021. Spanish. doi:10.1016/j.nrl.2021.06.005
   Google Scholar
• Askari N, Hadizadeh M, Rashidifar M. A new insight into sex-specific non-coding RNAs and networks in response to SARS-CoV-2. Infect Genet Evol. 2022;97:105195. doi:10.1016/j.meegid.2021.105195
   Web of Science ®Google Scholar
• Bonilla-Muro MG, Hernandez de la Cruz ON, Gonzalez-Barrios JA. EsxA mainly contributes to the miR-155 overexpression in human monocyte-derived macrophages and potentially affect the immune mechanism of macrophages through miRNA dysregulation. J Microbiol Immunol Infect. 2021;54(2):185–192. doi:10.1016/j.jmii.2019.07.007
   Google Scholar
• Donyavi T, Bokharaei-Salim F, Baghi HB, et al. Acute and post-acute phase of COVID-19: analyzing expression patterns of miRNA-29a-3p, 146a-3p, 155-5p, and let-7b-3p in PBMC. Int Immunopharmacol. 2021;97:107641. doi:10.1016/j.intimp.2021.107641
   PubMed Web of Science ®Google Scholar
• Farr RJ, Rootes CL, Stenos J, Foo CH, Cowled C, Stewart CR. Detection of SARS-CoV-2 infection by microRNA profiling of the upper respiratory tract. PLoS One. 2022;17(4):e0265670. doi:10.1371/journal.pone.0265670
   Web of Science ®Google Scholar
• Garcia-Hidalgo MC, Gonzalez J, Benitez ID, et al. Identification of circulating microRNA profiles associated with pulmonary function and radiologic features in survivors of SARS-CoV-2-induced ARDS. Emerg Microbes Infect. 2022;11(1):1537–1549. doi:10.1080/22221751.2022.2081615
   PubMed Web of Science ®Google Scholar
• Iravani Saadi M, Ramzi M, Hesami Z, et al. MiR-181a and -b expression in acute lymphoblastic leukemia and its correlation with acute graft-versus-host disease after hematopoietic stem cell transplantation, COVID-19 and torque teno viruses. Virusdisease;2021. 32(4):727-736. doi:10.1007/s13337-021-00653-y
   Google Scholar
• Li C, Wang R, Wu A, et al. SARS-COV-2 as potential microRNA sponge in COVID-19 patients. BMC Med Genomics. 2022;15(Suppl 2):94. doi:10.1186/s12920-022-01243-7
   Web of Science ®Google Scholar
• Martinez-Fleta P, Vera-Tome P, Jimenez-Fernandez M, et al. A differential signature of circulating miRNAs and cytokines between COVID-19 and community-acquired pneumonia uncovers novel physiopathological mechanisms of COVID-19. Front Immunol. 2021;12:815651. doi:10.3389/fimmu.2021.815651
   Web of Science ®Google Scholar
• Molinero M, Benitez ID, Gonzalez J, et al. Bronchial aspirate-based profiling identifies microRNA signatures associated with COVID-19 and fatal disease in critically ill patients. Front Med. 2021;8:756517. doi:10.3389/fmed.2021.756517
   Web of Science ®Google Scholar
• O’Connell RM, Rao DS, Baltimore D. microRNA regulation of inflammatory responses. Annu Rev Immunol. 2012;30:295–312. doi:10.1146/annurev-immunol-020711-075013
   PubMed Web of Science ®Google Scholar
• Park JH, Choi Y, Lim CW, et al. Potential therapeutic effect of microRNAs in extracellular vesicles from mesenchymal stem cells against SARS-CoV-2. Cells. 2021;10(9):2393. doi:10.3390/cells10092393
   Web of Science ®Google Scholar
• Wang Y, Zhu X, Jiang XM, et al. Decreased inhibition of exosomal miRNAs on SARS-CoV-2 replication underlies poor outcomes in elderly people and diabetic patients. Signal Transduct Target Ther. 2021;6(1):300. doi:10.1038/s41392-021-00716-y
   PubMed Web of Science ®Google Scholar
• Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc. 2008;3(6):1101–1108. doi:10.1038/nprot.2008.73
   PubMed Web of Science ®Google Scholar
• Chu M, Fan Y, Wu L, et al. Knockdown of lncRNA BDNF-AS inhibited the progression of multiple myeloma by targeting the miR-125a/b-5p-BCL2 axis. Immun Ageing. 2022;19(1):3. doi:10.1186/s12979-021-00258-5
   PubMed Web of Science ®Google Scholar
• Cull AH, Snetsinger B, Buckstein R, Wells RA, Rauh MJ. Tet2 restrains inflammatory gene expression in macrophages. Exp Hematol. 2017;55(56–70):e13. doi:10.1016/j.exphem.2017.08.001
   Web of Science ®Google Scholar
• Fu B, Wang L, Ding H, Schwamborn JC, Li S, Dorf ME. TRIM32 senses and restricts Influenza A virus by ubiquitination of PB1 polymerase. PLoS Pathog. 2015;11(6):e1004960. doi:10.1371/journal.ppat.1004960
   PubMed Web of Science ®Google Scholar
• Jablonski KA, Gaudet AD, Amici SA, Popovich PG, Guerau-de-Arellano M. Control of the inflammatory macrophage transcriptional signature by miR-155. PLoS One. 2016;11(7):e0159724. doi:10.1371/journal.pone.0159724
   PubMed Web of Science ®Google Scholar
• Kar P, Saleh EIMM, Jaishee N, et al. Computational profiling of natural compounds as promising inhibitors against the spike proteins of SARS-CoV-2 wild-type and the variants of concern, viral cell-entry process, and cytokine storm in COVID-19. J Cell Biochem. 2022;123(5):964–986. doi:10.1002/jcb.30243
   Web of Science ®Google Scholar
• Liu G, Wan Q, Li J, Hu X, Gu X, Xu S. Silencing miR-125b-5p attenuates inflammatory response and apoptosis inhibition in mycobacterium tuberculosis-infected human macrophages by targeting DNA damage-regulated autophagy modulator 2 (DRAM2). Cell Cycle. 2020;19(22):3182–3194. doi:10.1080/15384101.2020.1838792
   PubMed Web of Science ®Google Scholar
• Muller MB, Hubner M, Li L, et al. Cell-crossing functional network driven by microRNA-125a regulates endothelial permeability and monocyte trafficking in acute inflammation. Front Immunol. 2022;13:826047. doi:10.3389/fimmu.2022.826047
   Web of Science ®Google Scholar
• Nguyen HN, Noss EH, Mizoguchi F, et al. Autocrine loop involving IL-6 family member LIF, LIF receptor, and STAT4 drives sustained fibroblast production of inflammatory mediators. Immunity. 2017;46(2):220–232. doi:10.1016/j.immuni.2017.01.004
   PubMed Web of Science ®Google Scholar
• Sudhahar V, Das A, Horimatsu T, et al. Copper transporter ATP7A (Copper-Transporting P-Type ATPase/Menkes ATPase) limits vascular inflammation and aortic aneurysm development: role of MicroRNA-125b. Arterioscler Thromb Vasc Biol. 2019;39(11):2320–2337. doi:10.1161/ATVBAHA.119.313374
   Web of Science ®Google Scholar
• Xu J, Liu Y, Deng M, et al. MicroRNA221-3p modulates Ets-1 expression in synovial fibroblasts from patients with osteoarthritis of temporomandibular joint. Osteoarthritis Cartilage. 2016;24(11):2003–2011. doi:10.1016/j.joca.2016.06.011
   Web of Science ®Google Scholar
• Zeng H, Zhao B, Zhang D, et al. Viola yedoensis Makino formula alleviates DNCB-induced atopic dermatitis by activating JAK2/STAT3 signaling pathway and promoting M2 macrophages polarization. Phytomedicine. 2022;103:154228. doi:10.1016/j.phymed.2022.154228
   PubMed Web of Science ®Google Scholar
• Zhang D, Yao X, Teng Y, et al. Adipocytes-derived exosomal microRNA-1224 inhibits M2 macrophage polarization in obesity-induced adipose tissue inflammation via MSI2-mediated Wnt/beta-catenin axis. Mol Nutr Food Res;2022. e2100889. doi:10.1002/mnfr.202100889
   Web of Science ®Google Scholar
• Fayyad-Kazan M, Makki R, Skafi N, et al. Circulating miRNAs: potential diagnostic role for coronavirus disease 2019 (COVID-19). Infect Genet Evol. 2021;94:105020. doi:10.1016/j.meegid.2021.105020
   Web of Science ®Google Scholar
• Tang H, Gao Y, Li Z, et al. The noncoding and coding transcriptional landscape of the peripheral immune response in patients with COVID-19. Clin Transl Med. 2020;10(6):e200. doi:10.1002/ctm2.200
   PubMed Web of Science ®Google Scholar
• Huang CW, Tsai KN, Chen YS, Chang RY. Differential miRNA expression profiling reveals correlation of miR125b-5p with persistent infection of Japanese encephalitis virus. Int J Mol Sci. 2021;22(8):4218.
   Web of Science ®Google Scholar
• Kuchipudi SV. The complex role of STAT3 in viral infections. J Immunol Res. 2015;2015:272359. doi:10.1155/2015/272359
   PubMed Web of Science ®Google Scholar
• Alivernini S, Gremese E, McSharry C, et al. MicroRNA-155-at the critical interface of innate and adaptive immunity in arthritis. Front Immunol. 2017;8:1932. doi:10.3389/fimmu.2017.01932
   PubMed Web of Science ®Google Scholar
• Vigorito E, Kohlhaas S, Lu D, Leyland R. miR-155: an ancient regulator of the immune system. Immunol Rev. 2013;253(1):146–157. doi:10.1111/imr.12057
   PubMed Web of Science ®Google Scholar
• Fatima M, Kumari R, Schwamborn JC, et al. Tripartite containing motif 32 modulates proliferation of human neural precursor cells in HIV-1 neurodegeneration. Cell Death Differ. 2016;23(5):776–786. doi:10.1038/cdd.2015.138
   PubMed Web of Science ®Google Scholar
• Uchil PD, Hinz A, Siegel S, et al. TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. J Virol. 2013;87(1):257–272. doi:10.1128/JVI.01804-12
   PubMed Web of Science ®Google Scholar
• de Gonzalo-Calvo D, Benitez ID, Pinilla L, et al. Circulating microRNA profiles predict the severity of COVID-19 in hospitalized patients. Transl Res. 2021;236:147–159. doi:10.1016/j.trsl.2021.05.004
   PubMed Web of Science ®Google Scholar
• Li S, Duan X, Li Y, et al. Differentially expressed immune response genes in COVID-19 patients based on disease severity. Aging. 2021;13(7):9265–9276. doi:10.18632/aging.202877
   Google Scholar
• Luo Y, Fu Y, Tan T, et al. Screening of lncRNA-miRNA-mRNA coexpression regulatory networks involved in acute traumatic coagulation dysfunction based on CTD, GeneCards, and PharmGKB databases. Oxid Med Cell Longev. 2022;2022:7280312. doi:10.1155/2022/7280312
   Web of Science ®Google Scholar
• Zhao Y, Lang Y, Zhang M, Liang S, Zhu X, Liu Z. miR-125b disrupts mitochondrial dynamics via targeting Mitofusin 1 in cisplatin-induced acute kidney injury. Kidney Dis. 2022;8(2):137–147. doi:10.1159/000520140
   Google Scholar
• Feng X, Bao J, Song C, et al. Functional role of miR155 in physiological and pathological processes of liver injury (Review). Mol Med Rep. 2021;24(4):714. doi:10.3892/mmr.2021.12353
   Web of Science ®Google Scholar
• de Gonzalo-Calvo D, Cenarro A, Garlaschelli K, et al. Translating the microRNA signature of microvesicles derived from human coronary artery smooth muscle cells in patients with familial hypercholesterolemia and coronary artery disease. J Mol Cell Cardiol. 2017;106:55–67. doi:10.1016/j.yjmcc.2017.03.005
   PubMed Web of Science ®Google Scholar
• Haroun RA, Osman WH, Amin RE, Hassan AK, Abo-Shanab WS, Eessa AM. Circulating plasma miR-155 is a potential biomarker for the detection of SARS-CoV-2 infection. Pathology. 2022;54(1):104–110. doi:10.1016/j.pathol.2021.09.006
   Web of Science ®Google Scholar
• Pociask DA, Robinson KM, Chen K, et al. Epigenetic and transcriptomic regulation of lung repair during recovery from influenza infection. Am J Pathol. 2017;187(4):851–863. doi:10.1016/j.ajpath.2016.12.012
   Web of Science ®Google Scholar
• Koranteng RD, Swindle EJ, Davis BJ, et al. Differential regulation of mast cell cytokines by both dexamethasone and the p38 mitogen-activated protein kinase (MAPK) inhibitor SB203580. Clin Exp Immunol. 2004;137(1):81–87. doi:10.1111/j.1365-2249.2004.02510.x
   Web of Science ®Google Scholar
• Zhang H, Liao YS, Gong J, Liu J, Zhang H. Clinical characteristics and risk factors for liver injury in COVID-19 patients in Wuhan. World J Gastroenterol. 2020;26(31):4694–4702. doi:10.3748/wjg.v26.i31.4694
   Web of Science ®Google Scholar
• Kudose S, Batal I, Santoriello D, et al. Kidney biopsy findings in patients with COVID-19. J Am Soc Nephrol. 2020;31(9):1959–1968. doi:10.1681/ASN.2020060802
   PubMed Web of Science ®Google Scholar
• Coppola N, Potenza N, Pisaturo M, et al. Liver microRNA hsa-miR-125a-5p in HBV chronic infection: correlation with HBV replication and disease progression. PLoS One. 2013;8(7):e65336. doi:10.1371/journal.pone.0065336
   Web of Science ®Google Scholar
• Sacco G, Foucault G, Briere O, Annweiler C. COVID-19 in seniors: findings and lessons from mass screening in a nursing home. Maturitas. 2020;141:46–52. doi:10.1016/j.maturitas.2020.06.023
   Web of Science ®Google Scholar
• Shi JC, Chen XH, Yang Q, et al. A simple prediction model of hyperuricemia for use in a rural setting. Sci Rep. 2021;11(1):23300. doi:10.1038/s41598-021-02716-y
   Web of Science ®Google Scholar
• Tohme S, Yazdani HO, Rahman A, et al. The use of machine learning to create a risk score to predict survival in patients with hepatocellular carcinoma: a TCGA cohort analysis. Can J Gastroenterol Hepatol. 2021;2021:5212953. doi:10.1155/2021/5212953
   PubMed Web of Science ®Google Scholar
• Valim C, Ahmad R, Lanaspa M, et al. Responses to bacteria, virus, and malaria distinguish the etiology of pediatric clinical pneumonia. Am J Respir Crit Care Med. 2016;193(4):448–459. doi:10.1164/rccm.201506-1100OC
   PubMed Web of Science ®Google Scholar