Antibiofilm Activity of Essential Fatty Acids Against Candida albicans from Vulvovaginal Candidiasis and Bloodstream Infections

References

• Talapko J, Juzbašić M, Matijević T, et al. Candida albicans-The virulence factors and clinical manifestations of infection. J Fungi. 2021;7(2):79. doi:10.3390/jof7020079
   Web of Science ®Google Scholar
• Turner SA, Butler G. The Candida pathogenic species complex. Cold Spring Harb Perspect Med. 2014;4(9):a019778. doi:10.1101/cshperspect.a019778
   PubMed Web of Science ®Google Scholar
• Pappas PG, Lionakis MS, Arendrup MC, Ostrosky-Zeichner L, Kullberg BJ. Invasive candidiasis. Nat Rev Dis Primers. 2018;4(1):18026. doi:10.1038/nrdp.2018.26
   PubMed Web of Science ®Google Scholar
• Pereira R, Dos Santos Fontenelle RO, de Brito EHS, de Morais SM. Biofilm of Candida albicans: formation, regulation and resistance. J Appl Microbiol. 2021;131(1):11–22. doi:10.1111/jam.14949
   PubMed Web of Science ®Google Scholar
• Cavalheiro M, Teixeira MC. Candida Biofilms: threats, challenges, and promising strategies. Front Med. 2018;5:28. doi:10.3389/fmed.2018.00028
   PubMed Web of Science ®Google Scholar
• Wall G, Montelongo-Jauregui D, Vidal Bonifacio B, Lopez-Ribot JL, Uppuluri P. Candida albicans biofilm growth and dispersal: contributions to pathogenesis. Curr Opin Microbiol. 2019;52:1–6. doi:10.1016/j.mib.2019.04.001
   PubMed Web of Science ®Google Scholar
• Sustr V, Foessleitner P, Kiss H, Farr A. Vulvovaginal candidosis: current concepts, challenges and perspectives. J Fungi. 2020;6(4):267. doi:10.3390/jof6040267
   Web of Science ®Google Scholar
• Rodríguez-Cerdeira C, Gregorio MC, Molares-Vila A, et al. Biofilms and vulvovaginal candidiasis. Colloids Surf B Biointerfaces. 2019;174:110–125. doi:10.1016/j.colsurfb.2018.11.011
   PubMed Web of Science ®Google Scholar
• Rodríguez-Cerdeira C, Martínez-Herrera E, Carnero-Gregorio M, et al. Pathogenesis and clinical relevance of Candida biofilms in vulvovaginal candidiasis. Front Microbiol. 2020;11:544480. doi:10.3389/fmicb.2020.544480
   PubMed Web of Science ®Google Scholar
• Tortorano AM, Prigitano A, Morroni G, Brescini L, Barchiesi F. Candidemia: evolution of drug resistance and novel therapeutic approaches. Infect Drug Resist. 2021;14:5543–5553. doi:10.2147/IDR.S274872
   PubMed Web of Science ®Google Scholar
• Xiao Z, Wang Q, Zhu F, An Y. Epidemiology, species distribution, antifungal susceptibility and mortality risk factors of candidemia among critically ill patients: a retrospective study from 2011 to 2017 in a teaching hospital in China. Antimicrob Resist Infect Control. 2019;8(1):89. doi:10.1186/s13756-019-0534-2
   PubMed Web of Science ®Google Scholar
• Vitális E, Nagy F, Tóth Z, et al. Candida biofilm production is associated with higher mortality in patients with candidaemia. Mycoses. 2020;63(4):352–360. doi:10.1111/myc.13049
   Web of Science ®Google Scholar
• Tascini C, Sozio E, Corte L, et al. The role of biofilm forming on mortality in patients with candidemia: a study derived from real world data. Infect Dis. 2018;50(3):214–219. doi:10.1080/23744235.2017.1384956
   PubMed Web of Science ®Google Scholar
• Soldini S, Posteraro B, Vella A, et al. Microbiologic and clinical characteristics of biofilm-forming Candida parapsilosis isolates associated with fungaemia and their impact on mortality. Clin Microbiol Infect. 2018;24(7):771–777. doi:10.1016/j.cmi.2017.11.005
   PubMed Web of Science ®Google Scholar
• Sasani E, Khodavaisy S, Rezaie S, Salehi M, Yadegari MH. The relationship between biofilm formation and mortality in patients with Candida tropicalis candidemia. Microb Pathog. 2021;155:104889. doi:10.1016/j.micpath.2021.104889
   Web of Science ®Google Scholar
• Casillas-Vargas G, Ocasio-Malavé C, Medina S, et al. Antibacterial fatty acids: an update of possible mechanisms of action and implications in the development of the next-generation of antibacterial agents. Prog Lipid Res. 2021;82:101093. doi:10.1016/j.plipres.2021.101093
   PubMed Web of Science ®Google Scholar
• Thibane VS, Ells R, Hugo A, et al. Polyunsaturated fatty acids cause apoptosis in C. albicans and C. dubliniensis biofilms. Biochim Biophys Acta. 2012;1820(10):1463–1468. doi:10.1016/j.bbagen.2012.05.004
   Web of Science ®Google Scholar
• Kuloyo O, Fourie R, Cason E, Albertyn J, Pohl CH. Transcriptome analyses of Candida albicans biofilms, exposed to arachidonic acid and fluconazole, indicates potential drug targets. G3. 2020;10(9):3099–3108. doi:10.1534/g3.120.401340
   Web of Science ®Google Scholar
• Kim YG, Lee JH, Park JG, Lee J. Inhibition of Candida albicans and Staphylococcus aureus biofilms by centipede oil and linoleic acid. Biofouling. 2020;36(2):126–137. doi:10.1080/08927014.2020.1730333
   PubMed Web of Science ®Google Scholar
• Jamiu AT, Albertyn J, Sebolai O, Gcilitshana O, Pohl CH. Inhibitory effect of polyunsaturated fatty acids alone or in combination with fluconazole on Candida krusei biofilms in vitro and in Caenorhabditis elegans. Med Mycol. 2021;59(12):1225–1237. doi:10.1093/mmy/myab055
   Web of Science ®Google Scholar
• Shareck J, Nantel A, Belhumeur P. Conjugated linoleic acid inhibits hyphal growth in Candida albicans by modulating Ras1p cellular levels and downregulating TEC1 expression. Eukaryot Cell. 2011;10(4):565–577. doi:10.1128/EC.00305-10
   PubMedGoogle Scholar
• Thibane VS, Kock JL, Ells R, van Wyk PW, Pohl CH. Effect of marine polyunsaturated fatty acids on biofilm formation of Candida albicans and Candida dubliniensis. Mar Drugs. 2010;8(10):2597–2604. doi:10.3390/md8102597
   PubMed Web of Science ®Google Scholar
• Saini RK, Keum YS. Omega-3 and omega-6 polyunsaturated fatty acids: dietary sources, metabolism, and significance - A review. Life Sci. 2018;203:255–267. doi:10.1016/j.lfs.2018.04.049
   PubMed Web of Science ®Google Scholar
• Wayne P. Clinical and Laboratory Standards Institute: Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts. 4th ed. CLSI standard M27; 2017.
   Google Scholar
• Gulati M, Lohse MB, Ennis CL, et al. In vitro culturing and screening of Candida albicans biofilms. Curr Protoc Microbiol. 2018;50(1):e60. doi:10.1002/cpmc.60
   Google Scholar
• El-Houssaini HH, Elnabawy OM, Nasser HA, Elkhatib WF. Correlation between antifungal resistance and virulence factors in Candida albicans recovered from vaginal specimens. Microb Pathog. 2019;128:13–19. doi:10.1016/j.micpath.2018.12.028
   PubMed Web of Science ®Google Scholar
• Wang Y, Pei Z, Lou Z, Wang H. Evaluation of anti-biofilm capability of cordycepin against Candida albicans. Infect Drug Resist. 2021;14:435–448. doi:10.2147/IDR.S285690
   Web of Science ®Google Scholar
• Wei M, Wang P, Wang S, Yang C, Gu L. HB&L system for rapid phenotypic detection of clinical carbapenem-resistant Enterobacterales isolates. J Glob Antimicrob Resist. 2021;26:272–278. doi:10.1016/j.jgar.2021.02.036
   Web of Science ®Google Scholar
• Koehler P, Stecher M, Cornely OA, et al. Morbidity and mortality of candidaemia in Europe: an epidemiologic meta-analysis. Clin Microbiol Infect. 2019;25(10):1200–1212. doi:10.1016/j.cmi.2019.04.024
   PubMed Web of Science ®Google Scholar
• Monfredini PM, Souza ACR, Cavalheiro RP, Siqueira RA, Colombo AL. Clinical impact of Candida spp. biofilm production in a cohort of patients with candidemia. Med Mycol. 2018;56(7):803–808. doi:10.1093/mmy/myx133
   Web of Science ®Google Scholar
• Gharaghani M, Rezaei-Matehkolaei A, Hardani AK, Zarei Mahmoudabadi A. Pediatric candiduria, epidemiology, genotype distribution and virulence factors of Candida albicans. Microb Pathog. 2021;160:105173. doi:10.1016/j.micpath.2021.105173
   Web of Science ®Google Scholar
• Hacioglu M, Guzel CB, Savage PB, Tan ASB. Antifungal susceptibilities, in vitro production of virulence factors and activities of ceragenins against Candida spp. isolated from vulvovaginal candidiasis. Med Mycol. 2019;57(3):291–299. doi:10.1093/mmy/myy023
   PubMed Web of Science ®Google Scholar
• Marak MB, Dhanashree B. Antifungal susceptibility and biofilm production of Candida spp. isolated from clinical samples. Int J Microbiol. 2018;2018:7495218. doi:10.1155/2018/7495218
   PubMed Web of Science ®Google Scholar
• Tulasidas S, Rao P, Bhat S, Manipura R. A study on biofilm production and antifungal drug resistance among Candida species from vulvovaginal and bloodstream infections. Infect Drug Resist. 2018;11:2443–2448. doi:10.2147/IDR.S179462
   PubMed Web of Science ®Google Scholar
• Weerasekera MM, Wijesinghe GK, Jayarathna TA, et al. Culture media profoundly affect Candida albicans and Candida tropicalis growth, adhesion and biofilm development. Mem Inst Oswaldo Cruz. 2016;111(11):697–702. doi:10.1590/0074-02760160294
   Web of Science ®Google Scholar
• Lee Y, Puumala E, Robbins N, Cowen LE. Antifungal drug resistance: molecular mechanisms in Candida albicans and beyond. Chem Rev. 2021;121(6):3390–3411. doi:10.1021/acs.chemrev.0c00199
   PubMed Web of Science ®Google Scholar
• de Barros PP, Rossoni RD, de Souza CM, Scorzoni L, Fenley JC, Junqueira JC. Candida biofilms: an update on developmental mechanisms and therapeutic challenges. Mycopathologia. 2020;185(3):415–424. doi:10.1007/s11046-020-00445-w
   PubMed Web of Science ®Google Scholar
• Djuricic I, Calder PC. Beneficial outcomes of omega-6 and omega-3 polyunsaturated fatty acids on human health: an update for 2021. Nutrients. 2021;13(7):2421. doi:10.3390/nu13072421
   PubMed Web of Science ®Google Scholar
• Abdelhamid AS, Brown TJ, Brainard JS, et al. Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2018;7(7):CD003177. doi:10.1002/14651858.CD003177.pub3
   Web of Science ®Google Scholar
• Freitas RDS, Campos MM. Protective effects of omega-3 fatty acids in cancer-related complications. Nutrients. 2019;11(5):945. doi:10.3390/nu11050945
   PubMed Web of Science ®Google Scholar
• Dong X, Li S, Chen J, Li Y, Wu Y, Zhang D. Association of dietary ω-3 and ω-6 fatty acids intake with cognitive performance in older adults: national Health and nutrition examination Survey (NHANES) 2011–2014. Nutr J. 2020;19(1):25. doi:10.1186/s12937-020-00547-7
   PubMed Web of Science ®Google Scholar
• Christen WG, Schaumberg DA, Glynn RJ, Buring JE. Dietary ω-3 fatty acid and fish intake and incident age-related macular degeneration in women. Arch Ophthalmol. 2011;129(7):921–929. doi:10.1001/archophthalmol.2011.34
   Google Scholar
• Shahidi F, Ambigaipalan P. Omega-3 polyunsaturated fatty acids and their health benefits. Annu Rev Food Sci Technol. 2018;9(1):345–381. doi:10.1146/annurev-food-111317-095850
   PubMed Web of Science ®Google Scholar
• Guimarães A, Venâncio A. The potential of fatty acids and their derivatives as antifungal agents: a review. Toxins. 2022;14(3):188. doi:10.3390/toxins14030188
   Web of Science ®Google Scholar
• Kumar P, Lee JH, Beyenal H, Lee J. Fatty acids as antibiofilm and antivirulence agents. Trends Microbiol. 2020;28(9):753–768. doi:10.1016/j.tim.2020.03.014
   PubMed Web of Science ®Google Scholar
• EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific opinion on the tolerable upper intake level of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA). EFSA J. 2012;10(7):2815.
   Google Scholar
• U.S. Department of Agriculture. Agricultural Research Service. Nutrient intakes from food: mean amounts consumed per individual, by gender and age. Available from: http://www.ars.usda.gov/ba/bhnrc/fsrg. Accessed April 25, 2014.
   Google Scholar