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Infection and Drug Resistance Volume 15, 2022 - Issue
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CASE REPORT

Analysis of a Refractory Case of Pediatric Meningitis Caused by Klebsiella pneumoniae Co-Resistant to Carbapenems and Polymyxins

Xu Huang1 Department of Clinical Laboratory, Children’s Hospital of Nanjing Medical University, Nanjing, People’s Republic of ChinaView further author information
,
Mingxiao Han2 Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0001-9689-3023View further author information
ORCID Icon,
Fei Jin3 Department of Laboratory, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of ChinaView further author information
,
Zhichen Zhu2 Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou, People’s Republic of ChinaView further author information
&
Haifang Zhang2 Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou, People’s Republic of ChinaCorrespondence[email protected]
View further author information
Pages 5309-5313 | Published online: 07 Sep 2022

References

  • Xing H, Cheng C, Zhang Y, et al. Successful treatment with intrathecal and intravenous polymyxin b-based combination against MDR Acinetobacter baumannii meningitis in pediatric patient: a case report. Front Pediatr. 2021;9:564991. doi:10.3389/fped.2021.564991
  • Abdallah M, Alsaleh H, Baradwan A, et al. Intraventricular tigecycline as a last resort therapy in a patient with difficult-to-treat healthcare-associated Acinetobacter baumannii ventriculitis: a case report. SN Compr Clin Med. 2020:1–5. doi:10.1007/s42399-020-00433-7
  • Chiotos K, Hayes M, Gerber JS, Tamma PD. Treatment of carbapenem-resistant Enterobacteriaceae infections in children. J Pediatric Infect Dis Soc. 2020;9(1):56–66. doi:10.1093/jpids/piz085
  • Pandey S, Li L, Deng XY, Cui DM, Gao L. Outcome following the treatment of ventriculitis caused by multi/extensive drug resistance gram negative bacilli; Acinetobacter baumannii and Klebsiella pneumonia. Front Neurol. 2018;9:1174. doi:10.3389/fneur.2018.01174
  • Jayol A, Poirel L, Brink A, Villegas MV, Yilmaz M, Nordmann P. Resistance to colistin associated with a single amino acid change in protein PmrB among Klebsiella pneumoniae isolates of worldwide origin. Antimicrob Agents Chemother. 2014;58(8):4762–4766. doi:10.1128/AAC.00084-14
  • Jin X, Chen Q, Shen F, et al. Resistance evolution of hypervirulent carbapenem-resistant Klebsiella pneumoniae ST11 during treatment with tigecycline and polymyxin. Emerg Microbes Infect. 2021;10(1):1129–1136. doi:10.1080/22221751.2021.1937327
  • Stary A. Zygomycosis and aspergillosis. Zigomicosis y aspergilosis. Monografias de Dermatologia. 1995;8(4):291–306. Spanish.
  • Xie M, Yang X, Xu Q, et al. Clinical evolution of ST11 carbapenem resistant and hypervirulent Klebsiella pneumoniae. Commun Biol. 2021;4(1):650. doi:10.1038/s42003-021-02148-4
  • Ahmadi M, Ranjbar R, Behzadi P, Mohammadian T. Virulence factors, antibiotic resistance patterns, and molecular types of clinical isolates of Klebsiella pneumoniae. Expert Rev Anti Infect Ther. 2022;20(3):463–472. doi:10.1080/14787210.2022.1990040
  • Tunkel AR, Hasbun R, Bhimraj A, et al. 2017 Infectious Diseases Society of America’s Clinical Practice Guidelines for healthcare-associated ventriculitis and meningitis. Clin Infect Dis. 2017;64(6):34–65. doi:10.1093/cid/ciw861
  • US Food and Drug Administration. Ceftazidime-avibactam prescribing information. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/206494s005,s006lbl.pdf. Accessed October 3, 2019.
  • Guimarães T, Nouér Simone A, Martins Roberta CR, et al. Ceftazidime-avibactam as salvage therapy for infections caused by enterobacteriales coresistant to carbapenems and polymyxins. Antimicrob Agents Chemother. 2019;63(10):e00528–19. doi:10.1128/AAC.00528-19
  • Ma X, He Y, Yu X, et al. Ceftazidime/avibactam improves the antibacterial efficacy of polymyxin B against polymyxin B heteroresistant KPC-2-producing Klebsiella pneumoniae and hinders emergence of resistant subpopulation in vitro. Front Microbiol. 2019;10:2029. doi:10.3389/fmicb.2019.02029

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