References
- PignoneMPhillipsCMulrowCUse of lipid lowering drugs for primary prevention of coronary heart disease: Meta-analysis of randomized trialsBMJ200032198398511039962
- TonkinAAylwardPColquhounDPrevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) study groupN Engl J Med1998339134913579841303
- EndresMStatins and strokeJ Cereb Blood Flow Metab2005251093111015815580
- LiaoJKBeyond lipid lowering: The role of statins in vascular protectionInt J Cardiol20028651812243846
- LiJLiJJHeJGNanJLGuoYLXiongCMAtorvastatin decreases C-reactive protein-induced inflammatory response in pulmonary artery smooth muscle cells by inhibiting nuclear factor-kappa B pathwayCardiovasc Ther20102881420074254
- TandonVBanoGKhajuriaVPariharAGuptaSPleiotropic effects of statinsIndian J Pharmacol2005377785
- ClelandJGMcMurrayJJKjekshusJPlasma concentration of amino-terminal pro-brain natriuretic peptide in chronic heart failure: Prediction of cardiovascular events and interaction with the effects of rosuvastatin. A report from CORONA (Controlled Rosuvastatin Multinational Trial in Heart Failure)J Am Coll Cardiol2009541850185919892235
- BarriosVEscobarERosuvastatin along the cardiovascular continuum: From JUPITER to AURORAExpert Rev Cardiovasc Ther200971317132719900015
- McMurrayJJKjekshusJGullestadLEffects of statin therapy according to plasma high-sensitivity C-reactive protein concentration in the controlled rosuvastatin multinational trial in heart failure (CORONA): A retrospective analysisCirculation20091202188219619917888
- KjeshkusJApreteiEBarriosVRosuvastatin in older patients with systolic heart failureN Engl J Med200735722482246117984166
- OkazakiHStatin prevents structural and electrical remodeling in rat hypertensive heart failure induced by chronic inhibition of NO synthesisCirculation2007116SupplII140
- KumagaiKNakashimaHSakuKThe HMG-CoA reductase inhibitor atorvastatin prevents atrial fibrillation by inhibiting inflammation in a canine sterile pericarditis modelCardiovasc Res20046210511115023557
- Young-XuYJabbourSGoldbergRUsefulness of statin drugs in protecting against atrial fibrillation in patients with coronary artery diseaseAm J Cardiol2003921379138314675569
- KulikASinghJPLevinRAvornJChoudhryNKAssociation between statin use and the incidence of atrial fibrillation following hospitalization for coronary artery diseaseAm J Cardiol20101051655166020538110
- SiuCLauCTseHPrevention of atrial fibrillation recurrence by statin therapy in patients with lone atrial fibrillation after successful cardioversionAm J Cardiol2003921343134514636918
- SunYFMeiYQJiQEffect of atorvastatin on postoperative atrial fibrillation in patients undergoing coronary artery bypass graftingZhonghua Yi Xue Za Zhi20098929882991 Chinese.20137710
- VedreAGurmHFroehlichJImpact of prior statin therapy on arrhythmic events in patients with acute coronary syndromes (from the Global Registry of Acute Coronary Events [GRACE])Am J Cardiol20091041613161719962463
- ChiuJHAbdelhadiRHChungMKEffect of statin therapy on risk of ventricular arrhythmia among patients with coronary artery disease and an implantable cardioverter-defibrillatorAm J Cardiol20059549049115695135
- VyasAKGuoHMossAJReduction in ventricular tachyarrhythmias with statins in the Multicenter Automatic Defibrillator Implantation Trial (MADIT) IIJ Am Coll Cardiol20064776977316487843
- KimJSKimJChoiDEfficacy of high-dose atorvastatin loading before primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: The STATIN STEMI trialJACC Cardiovasc Interv2010333233920298994
- PasceriVPattiGNuscaAPristipinoCRichichiGDi SciascioGRandomized trial of atorvastatin for reduction of myocardial damage during coronary intervention: Results from the ARMYDA (Atorvastatin for Reduction of MYocardial Damage during Angioplasty) trialCirculation200411067467815277322
- CaySCagirciGSenNBalbayYDurmazTAydogduSPrevention of peri-procedural myocardial injury using a single high loading dose of rosuvastatinCardiovasc Drugs Ther201024414720217203
- YunKHOhSKRheeSJYooNJKimNHJeongJW12-month follow-up results of high dose rosuvastatin loading before percutaneous coronary intervention in patients with acute coronary syndromeInt J Cardiol2011146687220471117
- RidkerPMMorrowDARoseLMRifaiNCannonCPBraunwaldERelative efficacy of atorvastatin 80 mg and pravastatin 40 mg in achieving the dual goals of low-density lipoprotein cholesterol <70 mg/dl and C-reactive protein <2 mg/l: An analysis of the PROVE-IT TIMI-22 trialJ Am Coll Cardiol2005451644164815893181
- GibsonCMPrideYBHochbergCPSloanSSabatineMSCannonCPEffect of intensive statin therapy on clinical outcomes among patients undergoing percutaneous coronary intervention for acute coronary syndrome. PCI-PROVE IT: A PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) substudyJ Am Coll Cardiol2009542290229519958964
- Di SciascioGPattiGPasceriVGaspardoneAColonnaGMontinaroAEfficacy of atorvastatin reload in patients on chronic statin therapy undergoing percutaneous coronary intervention: Results from the ARMYDA-RECAPTURE (Atorvastatin for Reduction of MYocardial Damage during Angioplasty) randomized trialJ Am Coll Cardiol20095455856519643320
- NovaroGMTiongIYPearceGLEffect of hydroxymethylglutaryl coenzyme A reductase inhibitors on the progression of calcific aortic stenosisCirculation20011042205220911684632
- AronowWSAhnCKronzonIAssociation of coronary risk factors and use of statins with progression of mild valvular stenosis in older personsAm J Cardiol20018869369511564402
- BellamyMFPellikkaPAKlarichKWAssociation of cholesterol levels, hydroxymethylglutaryl coenzyme A reductase inhibitor treatment, and progression of aortic stenosis in the communityJ Am Coll Cardiol2002401723173012446053
- MouraLMRamosSFZamoranoJLRosuvastatin affecting aortic valve endothelium to slow the progression of aortic stenosisJ Am Coll Cardiol20074955456117276178
- PagovichOWangELee-WongMStatins may improve asthmaJ Allergy Clin Immunol2010125 Abstr 178.
- StanekEAubertRXiaFStatin exposure reduces the risk of asthma-related hospitalizations and emergency room visits in asthmatic patients on inhaled corticosteroidsJ Allergy Clin Immunol2009123 Abstr 238.
- BlamounAIBattyGNDeBariVARashidAOSheikhMKhanMAStatins may reduce episodes of exacerbation and the requirement for intubation in patients with COPD: Evidence from a retrospective cohort studyInt J Clin Pract2008621373137818422598
- MortensenEMCopelandLAPughMJImpact of statins and ACE inhibitors on mortality after COPD exacerbationsRespir Res2009101919134192
- AlexeeffSELitonjuaAASparrowDVokonasPSSchwartzJStatin use reduces decline in lung function: VA Normative Aging StudyAm J Respir Crit Care Med200717674274717673694
- KeddissiJIYounisWGChbeirEADaherNNDernaikaTAKinasewitzGTThe use of statins and lung function in current and former smokersChest20071321764177117908708
- ParikhAChildressCDeitrickKLinQRukstalisDYangWStatin-induced autophagy by inhibition of geranylgeranyl biosynthesis in prostate cancer PC3 cellsProstate20107097198120135644
- KatzMSCarrollPRCowanJEChanJMD’AmicoAVAssociation of statin and nonsteroidal anti-inflammatory drug use with prostate cancer outcomes: Results from CaPSUREBJU Int201010662763220151961
- GuttRTolnaarNKunnavakkamRKarrisonTWeichselbaumRRLiauwSLStatin use and the risk of prostate cancer recurrence in men treated with radiation therapyJ Clin Oncol2010282653265920421534
- BanezLLKlinkJCJayachandranJAssociation between statins and prostate tumor inflammatory infiltrate in men undergoing radical prostactectomyCancer Epidemiol Biomarkers Prev20101972272820160265
- ChoSJKimJSKimJMLeeYJJungJSSongISSimvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in miceInt J Cancer200812395195718521906
- KanekoRTsujiNAsanumaKTanebeHKobayashiDWatanabeNSurvivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor-induced apoptosis in cancerJ Biol Chem2007282192731928117472962
- AgarwalBBhendwalSHalmosBMossSFRameyWGHoltPRLovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cellsClin Cancer Res199952223222910473109
- PoynterJNGruberSBHigginsPDStatins and the risk of colorectal cancerN Engl J Med20053522184219215917383
- CooganPFSmithJRosenbergLStatin use and risk of colorectal cancerJ Natl Cancer Inst200799324017202111
- SiddiquiAANazarioHMahgoubAPandoveSCipherDSpechlerSJThe long-term use of statins is associated with a decreased incidence of adenomatous colon polypsDigestion200979172219246916
- KhuranaVBejjankiHRCalditoGOwensMWStatins reduce the risk of lung cancer in humans: A large case-control study of US veteransChest20071311282128817494779
- KhuranaVShethACalditoGBarkinJSStatins reduce the risk of pancreatic cancer in humans: A case-control study of half a million veteransPancreas20073426026517312467
- KhuranaVCalditoGAnkemMStatins might reduce the risk of renal cell carcinoma in humans: A case-control study of 500,000 veteransUrology20087111812218242378
- EverettBMGlynnRJMacFadyenJGRidkerPMRosuvastatin in the prevention of stroke among men and women with elevated levels of C-reactive protein: Justification for the use of statins in prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER)Circulation201012114315020026779
- SugawaraTAyerRZhangJHRole of statins in cerebral vasospasmActa Neurochir Suppl200810428729018457003
- LapchakPAHanMKThe 3-hydroxy-3-methyglutaryl A reductase inhibitor simvastatin reduces thrombolytic-induced intracerebral hemorrhage in embolized rabbitsBrain Res2009130314415019781532
- SterzerPMeintzschelFRöslerALanfermannHSteinmetzHSitzerMPravastatin improves cerebral vasomotor reactivity in patients with subcortical small-vessel diseaseStroke2001322817282011739979
- AmarencoPLabreucheJLipid management in the prevention of stroke: Review and updated meta-analysis of statins for stroke preventionLancet Neurol2009845346319375663
- NavalNSAbdelhakTAZeballosPUrrunagaNMirskiMACarhuapomaJRPrior statin use reduces mortality in intracerebral hemorrhageNeurocrit Care2008861217701108
- SillbergVAWellsGAPerryJJDo statins improve outcomes and reduce the incidence of vasospasm after aneurysmal subarachnoid hemorrhage: A meta-analysisStroke2008392622262618658040
- Markovic-PleseSSinghAKSinghITherapeutic potential of statins in multiple sclerosis: Immune modulation, neuroprotection and neurorepairFuture Neurol2008315316720107624
- WeberMSZamvilSSStatins and demyelinationCurr Top Microbiol Immunol200831831332418219823
- CoorealeJVillaAThe blood-brain-barrier in multiple sclerosis: Functional roles and therapeutic monitoringAutoimmunity20074014816017453713
- IferganIWosikKCayrolRStatins reduce human blood-brain barrier permeability and restrict leukocyte migration: Relevance to multiple sclerosisAnn Neurol200660455516729291
- VollmerTKeyLDurkalskiVOral simvastatin treatment in relapsing-remitting multiple sclerosisLancet20043631607160815145635
- PaulFWaicziesSWuerfelJOral high-dose atorvastatin treatment in relapsing-remitting multiple sclerosisPLoS One20083e192818398457
- WangQYanJChenXStatins: Multiple neuroprotective mechanisms in neurodegenerative diseasesExper Neurol4182010 [Epub ahead of print].
- HarrisJRMiltonNGCholesterol in Alzheimer’s disease and other amyloidogenic disordersSubcell Biochem201051477520213540
- LiGShoferJBRhewICAge-varying association between statin use and incident Alzheimer’s diseaseJ Am Geriatr Soc2010581311131720533968
- RosenbergPBMielkeMMTschanzJEffects of cardiovascular medications on rate of functional decline in Alzheimer diseaseAm J Geriatr Psychiatry20081688389218978249
- GhoshARoyAMatrasJBrahmachariSGendelmanHEPahanKSimvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson’s diseaseJ Neurosci200929135431354619864567
- WolozinBWangSWLiNLeeALeeTAKazisLESimvastatin is associated with a reduced incidence of dementia and Parkinson’s diseaseBMC Med2007511117198546
- WahnerADBronsteinJMBordelonYMRitzBStatin use and the risk of Parkinson diseaseNeurology2008701418142218184918
- KostapanosMSLiberopoulosENElisafMSStatin pleiotropy against renal injuryJ Cardiometab Syndr20094E4E919245508
- EllerPEllerKWolfAMAtorvastatin attenuates murine anti-glomerular basement membrane glomerulonephritisKidney Int20107742843520016464
- OzsoyRCKoopmanMGKastleleinJJAriszLThe acute effect of atorvastatin on proteinuria in patients with chronic glomerulonephritisClin Nephrol20056324524915847250
- TangdhanakanondKRajaREffects of statins on erythropoieten responsiveness in type-2 diabetic versus non-diabetic hemodialysis patientsClin Nephrol2010731620040345
- PazikJOstrowskaJLewandowskiZRenin-angiotensin-aldosterone system inhibitors and statins prolong graft survival in post-transplant glomerulonephritisAnn Transplant200813414519034222
- KandzariDERebeizAGWangASketchMHJrContrast nephropathy: An evidence-based approach to preventionAm J Cardiovasc Drugs2003339540514728060
- KhanalSAttallahNSmithDEStatin therapy reduces contrast-induced nephropathy: An analysis of contemporary percutaneous interventionsAm J Med200511884384916084176
- PattiGNuscaAChelloMUsefulness of statin pretreatment to prevent contrast-induced nephropathy and to improve long-term outcome in patients undergoing percutaneous coronary interventionAm J Cardiol200810127928518237585
- BlaschkeSViereckVSchwarzGKlingerHMGuerluekSMüllerGAAnti-inflammatory effects of atorvastatin on peripheral blood mononuclear cells and synovial fibroblasts in rheumatoid arthritisScand J Rheumatol20093823523919247848
- LazzeriniPELorenziniSSelviESimvastatin inhibits cytokine production and nuclear factor-k B activation in interleukin 1-beta stimulated synoviocytes from rheumatoid arthritis patientsClin Exp Rheumatol20072569670018078616
- TikizCUtukOPirildarTEffects of angiotensin-converting enzyme inhibition and statin treatment on inflammatory markers and endothelial functions in patients with long-term rheumatoid arthritisJ Rheumatol2005322095210116265685
- AmitalHChodickGShalemYShalevVHMG-CoA reductase inhibitors (statins) provide primary prevention for rheumatoid arthritisArthritis Rheum200960Suppl 101174
- BauerDCHMG CoA reductase inhibitors and the skeleton: A comprehensive reviewOsteoporos Int20031427328212736772
- MajimaTKomatsuYFukaoANinomiyaKMatsumuraTNakaoKShort term effects of atorvastatin on bone turnover in male patients with hypercholesterolemiaEndocr J20075414515117185879
- TanriverdiHABarutASarikayaSStatins have additive effects to vertebral bone mineral density in combination with risedronate in hypercholesterolemic postmenopausal womenEur J Obstet Gynecol Reprod Biol2005120636815866088
- HatzigeorgiouCJacksonJLHydroxymethylglutaryl-coenzyme A reductase inhibitors and osteoporosis: A meta-analysisOsteoporos Int20051699099815744453
- MontagnaniAGonnelliSCepollaroCEffect of simvastatin treatment on bone mineral density and bone turnover in hypercholesterolemic postmenopausal women: A 1-year longitudinal studyBone20033242743312689687
- LounevaNHuamanGFertalaJJiménezSAInhibition of systemic sclerosis dermal fibroblast type I collagen production and gene expression by simvastatinArthritis Rheum2006541298130816575855
- KuwanaMPotential benefit of statins for vascular disease in systemic sclerosisCurr Opin Rheumatol20061859460017053504
- KuwanaMOkazakiYKaburakiJLong-term beneficial effects of statins on vascular manifestations in patients with systemic sclerosisMod Rheumatol20091953053519590932
- Abou-RayaAAbou-RayaSHelmiiMStatins: Potentially useful in therapy of systemic sclerosis-related Raynaud’s phenomenon and digital ulcersJ Rheumatol2009351801180818709692
- RayJGDyslipidemia, statins, and venous thromboembolism: A potential risk factor and a potential treatmentCurr Opin Pulm Med2003937838412904707
- AgarwalVBhardwajATongbramVWhat effect do statins have on the development of venous thromboembolism? A comprehensive meta-analysis of over 900,000 patientsInt J Clin Pract2010641375138320716146
- KhemasuwanDDivietroMLTangdhanakanondKPomerantzSCEigerGStatins decrease the occurrence of venous thromboembolism in patients with cancerAm J Med2010123606520102993
- KodamanPHDulebaAJStatins in the treatment of polycystic ovary syndromeSemin Reprod Med20082612713818181091
- RzepczynskaIJPiotrowskiPCWongDCressABVillanuevaJDulebaAJRole of isoprenylation in simvastatin-induced inhibition of ovarian theca-interstitial growth in the ratBiol Reprod20098185085519571257
- SathyapalanTKilpatrickESCoadyAMAtkinSLThe effect of atorvastatin in patients with polycystic ovary syndrome: A randomized double-blind placebo-controlled studyJ Clin Endocrinol Metab20099410310818940877
- BanaszewskaBPawelczykLSpaczynskiRDziuraJDulebaAJEffects of simvastatin and oral contraceptive agent on polycystic ovary syndrome: Prospective, randomized, crossover trialJ Clin Endocrinol Metab20079245646117105841
- TanJSMitchellPRochtchinaEWangJJStatins and the long-term risk of incident age-related macular degeneration: The Blue Mountains Eye StudyAm J Ophthalmol200714368568717386278
- SagaraNKawajiTTakanoAEffect of pitavistatin on experimental choroidal neovascularization in ratsExp Eye Res2007841074108017418120
- WilsonHLSchwartzDMBhattHRMcCullochCEDuncanJLStatin and aspirin therapy are associated with decreased rates of choroidal neovascularization among patients with age-related macular degenerationAm J Ophthalmol200413761562415059698
- McGwinGJrOwsleyCCurcioCACrainRJThe association between statin use and age related maculopathyBr J Ophthalmol2003871121112512928279
- KwongJCLiPRedelmeierDAInfluenza morbidity and mortality in elderly patients receiving statins: A cohort studyPLoS One20094e808719956645
- FrostFJPetersonHTollestrupKSkipperBInfluenza and COPD mortality protection as pleiotropic, dose-dependent effects of statinsChest20071311006101217426203
- VandermeerMThomasAKamimotoLRole of statins in preventing death among patients hospitalized with lab-confirmed influenza infectionsInfectious Diseases Society of America 47th annual meeting, 2009Boston, MAOctober 29–November 1, 2009 Abstr 706.
- JandaSYoungAFitzgeraldJMEtminanMSwistonJThe effect of statins on mortality from severe infections and sepsis: A systematic review and meta-analysisJ Crit Care201025656.e7656.e2220413251
- DobeshPPKlepserDGMcGuireTRMorganCWOlsenKMReduction in mortality associated with statin therapy in patients with severe sepsisPharmacotherapy20092962163019476415
- HsuJAndresDRKnasinksiVPirschJSafdarNStatins are associated with improved outcomes of bloodstream infection in solid-organ transplant recipientsEur J Clin Microbiol Infect Dis2009281343135119669657
- SpanakisIKourkoumpetisTPelegALivanisGMylonakisEThe impact of statin therapy on candida colonization or infection among patients with diabetes type 2American Association of Clinical Endocrinologists 19th annual meeting, 2010Boston, MAApril 21–25, 2010 Abstr 401.