Patterns of Immune Infiltration and the Key Immune-Related Genes in Acute Type A Aortic Dissection in Bioinformatics Analyses

References

• Gudbjartsson T, Ahlsson A, Geirsson A, et al. Acute type A aortic dissection - a review. Scand Cardiovasc J: SCJ. 2020;54(1):1–13. doi:10.1080/14017431.2019.1660401
   PubMed Web of Science ®Google Scholar
• Jiang T, Si L. Identification of the molecular mechanisms associated with acute type A aortic dissection through bioinformatics methods. Braz J Med Biol Res. 2019;52(11):e8950. doi:10.1590/1414-431x20198950
   PubMed Web of Science ®Google Scholar
• Munir W, Chong JH, Harky A, Bashir M, Adams B. Type A aortic dissection: involvement of carotid artery and impact on cerebral malperfusion. Asian Cardiovasc Thorac Ann. 2020;218492320984329.
   Google Scholar
• Elsayed RS, Cohen RG, Fleischman F, Bowdish ME. Acute type A aortic dissection. Cardiol Clin. 2017;35(3):331–345. doi:10.1016/j.ccl.2017.03.004
   PubMed Web of Science ®Google Scholar
• Cifani N, Proietta M, Tritapepe L, et al. Stanford-A acute aortic dissection, inflammation, and metalloproteinases: a review. Ann Med. 2015;47(6):441–446. doi:10.3109/07853890.2015.1073346
   PubMed Web of Science ®Google Scholar
• Zhou Z, Liu Y, Zhu X, et al. Exaggerated autophagy in stanford type A aortic dissection: a transcriptome pilot analysis of human ascending aortic tissues. Genes. 2020;11(10):1187. doi:10.3390/genes11101187
   PubMed Web of Science ®Google Scholar
• Miao YR, Zhang Q, Lei Q, et al. ImmuCellAI: a unique method for comprehensive T-cell subsets abundance prediction and its application in cancer immunotherapy. Adv Sci. 2020;7(7):1902880. doi:10.1002/advs.201902880
   Web of Science ®Google Scholar
• Pan S, Wu D, Teschendorff AE, et al. JAK2-centered interactome hotspot identified by an integrative network algorithm in acute Stanford type A aortic dissection. PLoS One. 2014;9(2):e89406. doi:10.1371/journal.pone.0089406
   PubMed Web of Science ®Google Scholar
• Nie H, Qiu J, Wen S, Zhou W. Combining bioinformatics techniques to study the key immune-related genes in abdominal aortic aneurysm. Front Genet. 2020;11:579215. doi:10.3389/fgene.2020.579215
   PubMed Web of Science ®Google Scholar
• Chen H, Chen C, Yuan X, et al. Identification of immune cell landscape and construction of a novel diagnostic nomogram for Crohn’s disease. Front Genet. 2020;11:423. doi:10.3389/fgene.2020.00423
   PubMed Web of Science ®Google Scholar
• Xu WH, Wu J, Wang J, et al. Screening and identification of potential prognostic biomarkers in adrenocortical carcinoma. Front Genet. 2019;10:821. doi:10.3389/fgene.2019.00821
   PubMed Web of Science ®Google Scholar
• Ma L, Lu H, Chen R, et al. Identification of key genes and potential new biomarkers for ovarian aging: a study based on RNA-sequencing data. Front Genet. 2020;11:590660. doi:10.3389/fgene.2020.590660
   PubMed Web of Science ®Google Scholar
• Ritchie ME, Phipson B, Wu D, et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 2015;43(7):e47. doi:10.1093/nar/gkv007
   PubMed Web of Science ®Google Scholar
• Mei J, Yang X, Xia D, et al. Systematic summarization of the expression profiles and prognostic roles of the dishevelled gene family in hepatocellular carcinoma. Mol Genet Genom Med. 2020;8(9):e1384. doi:10.1002/mgg3.1384
   PubMed Web of Science ®Google Scholar
• Lei C, Yang D, Chen S, et al. Patterns of immune infiltration in stable and raptured abdominal aortic aneurysms: a gene-expression-based retrospective study. Gene. 2020;762:145056. doi:10.1016/j.gene.2020.145056
   PubMed Web of Science ®Google Scholar
• Nie H, Wang S, Wu Q, Xue D, Zhou W. Five immune-gene-signatures participate in the development and pathogenesis of Kawasaki disease. Immun Inflamm Dis. 2020.
   Web of Science ®Google Scholar
• Bhattacharya S, Andorf S, Gomes L, et al. ImmPort: disseminating data to the public for the future of immunology. Immunol Res. 2014;58(2–3):234–239. doi:10.1007/s12026-014-8516-1
   PubMed Web of Science ®Google Scholar
• Zhang YF, Meng LB, Hao ML, Yang JF, Zou T. Identification of co-expressed genes between atrial fibrillation and stroke. Front Neurol. 2020;11:184. doi:10.3389/fneur.2020.00184
   PubMed Web of Science ®Google Scholar
• Liang B, Li C, Zhao J. Identification of key pathways and genes in colorectal cancer using bioinformatics analysis. Med Oncol. 2016;33(10):111. doi:10.1007/s12032-016-0829-6
   PubMed Web of Science ®Google Scholar
• Niu X, Zhang J, Zhang L, et al. Weighted gene co-expression network analysis identifies critical genes in the development of heart failure after acute myocardial infarction. Front Genet. 2019;10:1214. doi:10.3389/fgene.2019.01214
   PubMed Web of Science ®Google Scholar
• Qi L, Liu B, Chen X, et al. Single-cell transcriptomic analysis reveals mitochondrial dynamics in oocytes of patients with polycystic ovary syndrome. Front Genet. 2020;11:396. doi:10.3389/fgene.2020.00396
   PubMed Web of Science ®Google Scholar
• Kumari N, Karmakar A, Chakrabarti S, Ganesan SK. Integrative computational approach revealed crucial genes associated with different stages of diabetic retinopathy. Front Genet. 2020;11:576442. doi:10.3389/fgene.2020.576442
   PubMed Web of Science ®Google Scholar
• Chen L, Zhang S, Zhang S, et al. Identification of long non-coding RNA-associated competing endogenous RNA network in the differentiation of chicken preadipocytes. Genes. 2019;10(10):795. doi:10.3390/genes10100795
   PubMed Web of Science ®Google Scholar
• Chin CH, Chen SH, Wu HH, Ho CW, Ko MT, Lin CY. cytoHubba: identifying hub objects and sub-networks from complex interactome. BMC Syst Biol. 2014;8(Suppl 4):S11. doi:10.1186/1752-0509-8-S4-S11
   PubMed Web of Science ®Google Scholar
• Ma Z, Xu J, Ru L, Zhu W. Identification of pivotal genes associated with the prognosis of gastric carcinoma through integrated analysis. Biosci Rep. 2021;41(4). doi:10.1042/BSR20203676
   Web of Science ®Google Scholar
• Chaudhary R, Balhara M, Jangir DK, Dangi M, Dangi M, Chhillar AK. In silico protein interaction network analysis of virulence proteins associated with invasive aspergillosis for drug discovery. Curr Top Med Chem. 2019;19(2):146–155. doi:10.2174/1568026619666181120150633
   PubMed Web of Science ®Google Scholar
• Wang X, Zhang H, Cao L, He Y, Ma A, Guo W. The role of macrophages in aortic dissection. Front Physiol. 2020;11:54. doi:10.3389/fphys.2020.00054
   PubMed Web of Science ®Google Scholar
• Del Porto F, Di Gioia C, Tritapepe L, et al. The multitasking role of macrophages in Stanford type A acute aortic dissection. Cardiology. 2014;127(2):123–129. doi:10.1159/000355253
   PubMed Web of Science ®Google Scholar
• Yoshida S, Yamamoto M, Aoki H, et al. STAT3 activation correlates with adventitial neutrophil infiltration in human aortic dissection. Ann Vasc Dis. 2019;12(2):187–193. doi:10.3400/avd.oa.19-00007
   PubMed Web of Science ®Google Scholar
• Bedel C, Selvi F. Association of platelet to lymphocyte and neutrophil to lymphocyte ratios with in-hospital mortality in patients with type A acute aortic dissection. Braz J Cardiovasc Surg. 2019;34(6):694–698. doi:10.21470/1678-9741-2018-0343
   PubMed Web of Science ®Google Scholar
• Subramanian S, Turner MS, Ding Y, et al. Increased levels of invariant natural killer T lymphocytes worsen metabolic abnormalities and atherosclerosis in obese mice. J Lipid Res. 2013;54(10):2831–2841. doi:10.1194/jlr.M041020
   PubMed Web of Science ®Google Scholar
• Del Porto F, Proietta M, Tritapepe L, et al. Inflammation and immune response in acute aortic dissection. Ann Med. 2010;42(8):622–629. doi:10.3109/07853890.2010.518156
   PubMed Web of Science ®Google Scholar
• Barbetseas J, Alexopoulos N, Brili S, et al. Atherosclerosis of the aorta in patients with acute thoracic aortic dissection. Circulat J. 2008;72(11):1773–1776. doi:10.1253/circj.CJ-08-0433
   PubMed Web of Science ®Google Scholar
• Yu K, Zhu P, Dong Q, et al. Thymic stromal lymphopoietin attenuates the development of atherosclerosis in ApoE-/- mice. J Am Heart Assoc. 2013;2(5):e000391. doi:10.1161/JAHA.113.000391
   PubMed Web of Science ®Google Scholar
• Ju X, Ijaz T, Sun H, et al. Interleukin-6-signal transducer and activator of transcription-3 signaling mediates aortic dissections induced by angiotensin II via the T-helper lymphocyte 17-interleukin 17 axis in C57BL/6 mice. Arterioscler Thromb Vasc Biol. 2013;33(7):1612–1621. doi:10.1161/ATVBAHA.112.301049
   PubMed Web of Science ®Google Scholar
• Cifani N, Proietta M, Taurino M, Tritapepe L, Del Porto F. Monocyte subsets, stanford-a acute aortic dissection, and carotid artery stenosis: new evidences. J Immunol Res. 2019;2019:9782594. doi:10.1155/2019/9782594
   PubMed Web of Science ®Google Scholar
• Scheenstra MR, Martínez-Botía P, Acebes-Huerta A, et al. Comparison of the PU.1 transcriptional regulome and interactome in human and mouse inflammatory dendritic cells. J Leukoc Biol. 2020. doi:10.1002/JLB.6A1219-711RRR
   PubMed Web of Science ®Google Scholar
• Williams JW, Zaitsev K, Kim KW, et al. Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression. Nat Immunol. 2020;21(10):1194–1204. doi:10.1038/s41590-020-0768-4
   PubMed Web of Science ®Google Scholar
• Karadimou G, Gisterå A, Gallina AL, et al. Treatment with a Toll-like Receptor 7 ligand evokes protective immunity against atherosclerosis in hypercholesterolaemic mice. J Intern Med. 2020;288(3):321–334. doi:10.1111/joim.13085
   PubMed Web of Science ®Google Scholar
• Gao Y, Wang Z, Zhao J, et al. Involvement of B cells in the pathophysiology of β-aminopropionitrile-induced thoracic aortic dissection in mice. Exp Animals. 2019;68(3):331–339. doi:10.1538/expanim.18-0170
   PubMed Web of Science ®Google Scholar
• Peng LP, Cao Y, Zhao SL, Huang YX, Yang K, Huang W. Memory T cells delay the progression of atherosclerosis via AMPK signaling pathway. Ann Transl Med. 2019;7(23):782. doi:10.21037/atm.2019.11.20
   PubMed Web of Science ®Google Scholar
• Fazekas B, Moreno-Olivera A, Kelly Y, et al. Alterations in circulating lymphoid cell populations in systemic small vessel vasculitis are non-specific manifestations of renal injury. Clin Exp Immunol. 2018;191(2):180–188. doi:10.1111/cei.13058
   PubMed Web of Science ®Google Scholar
• Emgård J, Bergsten H, McCormick JK, et al. MAIT cells are major contributors to the cytokine response in group A streptococcal toxic shock syndrome. Proc Natl Acad Sci U S A. 2019;116(51):25923–25931. doi:10.1073/pnas.1910883116
   PubMed Web of Science ®Google Scholar
• Kimura N, Futamura K, Arakawa M, et al. Gene expression profiling of acute type A aortic dissection combined with in vitro assessment. Eur J Cardio-Thorac Surg. 2017;52(4):810–817. doi:10.1093/ejcts/ezx095
   PubMed Web of Science ®Google Scholar
• Anzai A, Shimoda M, Endo J, et al. Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture. Circ Res. 2015;116(4):612–623. doi:10.1161/CIRCRESAHA.116.304918
   PubMed Web of Science ®Google Scholar
• Brasier AR. The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular inflammation. Cardiovasc Res. 2010;86(2):211–218. doi:10.1093/cvr/cvq076
   PubMed Web of Science ®Google Scholar
• Liu H, Luo Z, Liu L, et al. Inflammatory biomarkers to predict adverse outcomes in postoperative patients with acute type A aortic dissection. Scand Cardiovasc J: SCJ. 2020;54(1):37–46. doi:10.1080/14017431.2019.1689289
   PubMed Web of Science ®Google Scholar
• Wu Q, Li J, Chen L, et al. Efficacy of interleukin-6 in combination with D-dimer in predicting early poor postoperative prognosis after acute stanford type a aortic dissection. J Cardiothorac Surg. 2020;15(1):172. doi:10.1186/s13019-020-01206-y
   PubMed Web of Science ®Google Scholar
• Bai Z, Gu J, Shi Y, Meng W. Effect of inflammation on the biomechanical strength of involved aorta in type A aortic dissection and ascending thoracic aortic aneurysm: an initial research. Anatol J Cardiol. 2018;20(2):85–92. doi:10.14744/AnatolJCardiol.2018.49344
   PubMed Web of Science ®Google Scholar
• Zhao JQ, Gao YX, Wu C, et al. [Effects of alprostadil in β-aminopropanitrile induced aortic dissection in a murine model]. Zhonghua Xin xue Guan Bing Za Zhi. 2020;48(8):682–688. [Chinese]. doi:10.3760/cma.j.cn112148-20190925-00592
   PubMedGoogle Scholar
• Luo FY, Liu ZH, Jiang HH, Lin GQ. Correlation between plasma level of monocyte chemotactic protein 1 and acute aortic dissection. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2015;37(3):352–354. doi:10.3881/j.issn.1000-503X.2015.03.021
   PubMedGoogle Scholar
• Lin J, Kakkar V, Lu X. Impact of MCP-1 in atherosclerosis. Curr Pharm Des. 2014;20(28):4580–4588. doi:10.2174/1381612820666140522115801
   PubMed Web of Science ®Google Scholar
• Tieu BC, Lee C, Sun H, et al. An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice. J Clin Invest. 2009;119(12):3637–3651. doi:10.1172/JCI38308
   PubMed Web of Science ®Google Scholar
• Peng F, Chang W, Sun Q, et al. HGF alleviates septic endothelial injury by inhibiting pyroptosis via the mTOR signalling pathway. Respir Res. 2020;21(1):215. doi:10.1186/s12931-020-01480-3
   PubMed Web of Science ®Google Scholar
• Hata N, Matsumori A, Yokoyama S, et al. Hepatocyte growth factor and cardiovascular thrombosis in patients admitted to the intensive care unit. Circulat J. 2004;68(7):645–649. doi:10.1253/circj.68.645
   PubMed Web of Science ®Google Scholar