Association of Cardiac Troponin T Concentration on Admission with Prognosis in Critically Ill Patients without Myocardial Infarction: A Cohort Study

References

• Antman EM. Decision making with cardiac troponin tests. N Engl J Med. 2002;346(26):2079–2082. doi:10.1056/NEJMe020049
   PubMed Web of Science ®Google Scholar
• Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: executive summary and recommendations. A report of the American College of Cardiology/American Heart Association task force on practice guidelines (committee on the management of patients with unstable angina). Circulation. 2000;102(10):1193–1209. doi:10.1161/01.cir.102.10.1193
   PubMed Web of Science ®Google Scholar
• Higgins JP, Higgins JA. Elevation of cardiac troponin I indicates more than myocardial ischemia. Clin Invest Med. 2003;26(3):133–147.
   PubMed Web of Science ®Google Scholar
• Wu AH. Increased troponin in patients with sepsis and septic shock: myocardial necrosis or reversible myocardial depression? Intensive Care Med. 2001;27(6):959–961. doi:10.1007/s001340100970
   PubMed Web of Science ®Google Scholar
• Hijazi Z, Siegbahn A, Andersson U, et al. High-sensitivity troponin I for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial. Circulation. 2014;129(6):625–634. doi:10.1161/CIRCULATIONAHA.113.006286
   PubMed Web of Science ®Google Scholar
• Horwich TB, Patel J, MacLellan WR, Fonarow GC. Cardiac troponin I is associated with impaired hemodynamics, progressive left ventricular dysfunction, and increased mortality rates in advanced heart failure. Circulation. 2003;108(7):833–838. doi:10.1161/01.CIR.0000084543.79097.34
   PubMed Web of Science ®Google Scholar
• Baillard C, Boussarsar M, Fosse JP, et al. Cardiac troponin I in patients with severe exacerbation of chronic obstructive pulmonary disease. Intensive Care Med. 2003;29(4):584–589. doi:10.1007/s00134-003-1635-0
   PubMed Web of Science ®Google Scholar
• Dubin RF, Li Y, He J, et al. Predictors of high sensitivity cardiac troponin T in chronic kidney disease patients: a cross-sectional study in the chronic renal insufficiency cohort (CRIC). BMC Nephrol. 2013;14:229. doi:10.1186/1471-2369-14-229
   PubMed Web of Science ®Google Scholar
• Antman EM, Tanasijevic MJ, Thompson B, et al. Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N Engl J Med. 1996;335(18):1342–1349. doi:10.1056/NEJM199610313351802
   PubMed Web of Science ®Google Scholar
• Willeit P, Welsh P, Evans JDW, et al. High-sensitivity cardiac troponin concentration and risk of first-ever cardiovascular outcomes in 154,052 participants. J Am Coll Cardiol. 2017;70(5):558–568. doi:10.1016/j.jacc.2017.05.062
   PubMed Web of Science ®Google Scholar
• Everett BM, Brooks MM, Vlachos HE, et al. Troponin and cardiac events in stable ischemic heart disease and diabetes. N Engl J Med. 2015;373(7):610–620. doi:10.1056/NEJMoa1415921
   PubMed Web of Science ®Google Scholar
• Lim W, Qushmaq I, Devereaux PJ, et al. Elevated cardiac troponin measurements in critically ill patients. Arch Intern Med. 2006;166(22):2446–2454. doi:10.1001/archinte.166.22.2446
   PubMed Web of Science ®Google Scholar
• Relos RP, Hasinoff IK, Beilman GJ. Moderately elevated serum troponin concentrations are associated with increased morbidity and mortality rates in surgical intensive care unit patients. Crit Care Med. 2003;31(11):2598–2603. doi:10.1097/01.CCM.0000089931.09635.D2
   PubMed Web of Science ®Google Scholar
• Edouard AR, Felten ML, Hebert JL, Cosson C, Martin L, Benhamou D. Incidence and significance of cardiac troponin I release in severe trauma patients. Anesthesiology. 2004;101(6):1262–1268. doi:10.1097/00000542-200412000-00004
   PubMed Web of Science ®Google Scholar
• Martin M, Mullenix P, Rhee P, Belzberg H, Demetriades D, Salim A. Troponin increases in the critically injured patient: mechanical trauma or physiologic stress? J Trauma. 2005;59(5):1086–1091. doi:10.1097/01.ta.0000190249.19668.37
   PubMedGoogle Scholar
• Johnson A, Bulgarelli L, Pollard T, Horng S, Celi LA, Mark R. MIMIC-IV (version 0.4). 2020. Available from: https://doi.org/10.13026/a3wn-hq05. Accessed March 8, 2021.
   Google Scholar
• Charlson M, Szatrowski TP, Peterson J, Gold J. Validation of a combined comorbidity index. J Clin Epidemiol. 1994;47(11):1245–1251. doi:10.1016/0895-4356(94)90129-5
   PubMed Web of Science ®Google Scholar
• Spies C, Haude V, Fitzner R, et al. Serum cardiac troponin T as a prognostic marker in early sepsis. Chest. 1998;113(4):1055–1063. doi:10.1378/chest.113.4.1055
   PubMed Web of Science ®Google Scholar
• Landesberg G, Vesselov Y, Einav S, Goodman S, Sprung CL, Weissman C. Myocardial ischemia, cardiac troponin, and long-term survival of high-cardiac risk critically ill intensive care unit patients. Crit Care Med. 2005;33(6):1281–1287. doi:10.1097/01.CCM.0000166607.22550.87
   PubMed Web of Science ®Google Scholar
• Klein Gunnewiek JMT, van de Leur J. Elevated troponin T concentrations in critically ill patients. Intensive Care Med. 2003;29(12):2317–2322. doi:10.1007/s00134-003-1953-2
   PubMed Web of Science ®Google Scholar
• Ostermann M, Lo J, Toolan M, et al. A prospective study of the impact of serial troponin measurements on the diagnosis of myocardial infarction and hospital and six-month mortality in patients admitted to ICU with non-cardiac diagnoses. Crit Care. 2014;18(2):R62. doi:10.1186/cc13818
   PubMed Web of Science ®Google Scholar
• Docherty AB, Sim M, Oliveira J, et al. Early troponin I in critical illness and its association with hospital mortality: a cohort study. Crit Care. 2017;21(1):216. doi:10.1186/s13054-017-1800-4
   PubMed Web of Science ®Google Scholar
• Reynolds T, Cecconi M, Collinson P, Rhodes A, Grounds RM, Hamilton MA. Raised serum cardiac troponin I concentrations predict hospital mortality in intensive care unit patients. Br J Anaesth. 2012;109(2):219–224. doi:10.1093/bja/aes141
   PubMed Web of Science ®Google Scholar
• Ver Elst KM, Spapen HD, Nguyen DN, Garbar C, Huyghens LP, Gorus FK. Cardiac troponins I and T are biological markers of left ventricular dysfunction in septic shock. Clin Chem. 2000;46(5):650–657. doi:10.1093/clinchem/46.5.650
   PubMed Web of Science ®Google Scholar
• Crewdson K, Thompson J, Thomas M. Cardiac troponin T is associated with mortality in patients admitted to critical care in a UK major trauma centre: a retrospective database analysis. J Intensive Care Soc. 2019;20(2):132–137. doi:10.1177/1751143718767782
   PubMedGoogle Scholar
• Thygesen K, Alpert JS, Jaffe AS, et al. Third universal definition of myocardial infarction. J Am Coll Cardiol. 2012;60(16):1581–1598. doi:10.1016/j.jacc.2012.08.001
   PubMed Web of Science ®Google Scholar
• Ammann P, Maggiorini M, Bertel O, et al. Troponin as a risk factor for mortality in critically ill patients without acute coronary syndromes. J Am Coll Cardiol. 2003;41(11):2004–2009. doi:10.1016/S0735-1097(03)00421-2
   PubMed Web of Science ®Google Scholar
• Hajsadeghi S, Gholami S, Gohardehi G, et al. Association between troponin T and ICU mortality, a changing trend. Cardiovasc J Afr. 2012;23(4):186–190. doi:10.5830/CVJA-2011-034
   PubMed Web of Science ®Google Scholar
• deFilippi CR, Tocchi M, Parmar RJ, et al. Cardiac troponin T in chest pain unit patients without ischemic electrocardiographic changes: angiographic correlates and long-term clinical outcomes. J Am Coll Cardiol. 2000;35(7):1827–1834. doi:10.1016/S0735-1097(00)00628-8
   PubMed Web of Science ®Google Scholar