Identification and Validation of Biglycan as Prognosis and Therapy Markers for Patients with Stomach Adenocarcinoma

References

• Gu Z, Wang L, Yao X, et al. ClC-3/SGK1 regulatory axis enhances the olaparib-induced antitumor effect in human stomach adenocarcinoma. Cell Death Dis. 2020;11:898. doi:10.1038/s41419-020-03107-3
   PubMed Web of Science ®Google Scholar
• Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136:E359–386. doi:10.1002/ijc.29210
   PubMed Web of Science ®Google Scholar
• Banks M, Graham D, Jansen M, et al. British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma. Gut. 2019;68:1545–1575. doi:10.1136/gutjnl-2018-318126
   PubMed Web of Science ®Google Scholar
• Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66:115–132. doi:10.3322/caac.21338
   PubMed Web of Science ®Google Scholar
• Frantz C, Stewart KM, Weaver VM. The extracellular matrix at a glance. J Cell Sci. 2010;123:4195–4200. doi:10.1242/jcs.023820
   PubMed Web of Science ®Google Scholar
• Hu L, Zang MD, Wang HX, et al. Biglycan stimulates VEGF expression in endothelial cells by activating the TLR signaling pathway. Mol Oncol. 2016;10:1473–1484. doi:10.1016/j.molonc.2016.08.002
   PubMed Web of Science ®Google Scholar
• Mintz MB, Sowers R, Brown KM, et al. An expression signature classifies chemotherapy-resistant pediatric osteosarcoma. Cancer Res. 2005;65:1748–1754. doi:10.1158/0008-5472.CAN-04-2463
   PubMed Web of Science ®Google Scholar
• Pan S, Cheng L, White JT, et al. Quantitative proteomics analysis integrated with microarray data reveals that extracellular matrix proteins, catenins, and p53 binding protein 1 are important for chemotherapy response in ovarian cancers. Omics. 2009;13:345–354. doi:10.1089/omi.2009.0008
   PubMed Web of Science ®Google Scholar
• Xing X, Gu X, Ma T, Ye H. Biglycan up-regulated vascular endothelial growth factor (VEGF) expression and promoted angiogenesis in colon cancer. Tumour Biol. 2015;36:1773–1780. doi:10.1007/s13277-014-2779-y
   PubMedGoogle Scholar
• Liu B, Xu T, Xu X, Cui Y, Xing X. Biglycan promotes the chemotherapy resistance of colon cancer by activating NF-kappaB signal transduction. Mol Cell Biochem. 2018;449:285–294. doi:10.1007/s11010-018-3365-1
   PubMed Web of Science ®Google Scholar
• Sun H, Wang X, Zhang Y, et al. Biglycan enhances the ability of migration and invasion in endometrial cancer. Arch Gynecol Obstet. 2016;293:429–438. doi:10.1007/s00404-015-3844-5
   PubMed Web of Science ®Google Scholar
• Tian Y, Xing Y, Zhang Z, Peng R, Zhang L, Sun Y. Bioinformatics analysis of key genes and circRNA-miRNA-mRNA regulatory network in gastric cancer. Biomed Res Int. 2020;2020:2862701. doi:10.1155/2020/2862701
   PubMed Web of Science ®Google Scholar
• Yang B, Zhang M, Luo T. Identification of potential core genes associated with the progression of stomach adenocarcinoma using bioinformatic analysis. Front Genet. 2020;11:517362. doi:10.3389/fgene.2020.517362
   PubMed Web of Science ®Google Scholar
• Zhao SF, Yin XJ, Zhao WJ, Liu LC, Wang ZP. Biglycan as a potential diagnostic and prognostic biomarker in multiple human cancers. Oncol Lett. 2020;19:1673–1682. doi:10.3892/ol.2020.11266
   PubMed Web of Science ®Google Scholar
• Subbarayan K, Seliger B. Tumor-dependent effects of proteoglycans and various glycosaminoglycan synthesizing enzymes and sulfotransferases on patients’ outcome. Curr Cancer Drug Targets. 2019;19:210–221. doi:10.2174/1568009618666180706165845
   PubMed Web of Science ®Google Scholar
• Schulz GB, Grimm T, Sers C, et al. Prognostic value and association with epithelial-mesenchymal transition and molecular subtypes of the proteoglycan biglycan in advanced bladder cancer. Urol Oncol. 2019;37:530 e539–530 e518. doi:10.1016/j.urolonc.2019.05.011
   Web of Science ®Google Scholar
• Pinto F, Santos-Ferreira L, Pinto MT, Gomes C, Reis CA. The extracellular small leucine-rich proteoglycan biglycan is a key player in gastric cancer aggressiveness. Cancers. 2021;13(6):1330. doi:10.3390/cancers13061330
   PubMed Web of Science ®Google Scholar
• Zhou Y, Bian S, Zhou X, et al. Single-cell multiomics sequencing reveals prevalent genomic alterations in tumor stromal cells of human colorectal cancer. Cancer Cell. 2020;38:818–828 e815. doi:10.1016/j.ccell.2020.09.015
   PubMed Web of Science ®Google Scholar
• Zhang H, Zhong J, Tu Y, et al. Integrated bioinformatics analysis identifies hub genes associated with the pathogenesis and prognosis of esophageal squamous cell carcinoma. Biomed Res Int. 2019;2019:2615921. doi:10.1155/2019/2615921
   PubMed Web of Science ®Google Scholar
• Morimoto H, Hida Y, Maishi N, et al. Biglycan, tumor endothelial cell secreting proteoglycan, as possible biomarker for lung cancer. Thorac Cancer. 2021;12(9):1347–1357. doi:10.1111/1759-7714.13907
   PubMed Web of Science ®Google Scholar
• Deng YD, Zhang XD, Yang XS, et al. Subacute toxicity of mesoporous silica nanoparticles to the intestinal tract and the underlying mechanism. J Hazard Mater. 2021;409:124502. doi:10.1016/j.jhazmat.2020.124502
   PubMed Web of Science ®Google Scholar
• Chen S, Guo D, Lei B, Bi J, Yang H. Biglycan protects human neuroblastoma cells from nitric oxide-induced death by inhibiting AMPK-mTOR mediated autophagy and intracellular ROS level. Biotechnol Lett. 2020;42:657–668. doi:10.1007/s10529-020-02818-z
   PubMed Web of Science ®Google Scholar
• Hull R, Mbita Z, Dlamini Z. Long non-coding RNAs (LncRNAs), viral oncogenomics, and aberrant splicing events: therapeutics implications. Am J Cancer Res. 2021;11:866–883.
   PubMed Web of Science ®Google Scholar
• Wang H, Chen XL, Liu K, et al. Associations between gastric cancer risk and virus infection other than Epstein-Barr virus: a systematic review and meta-analysis based on epidemiological studies. Clin Transl Gastroenterol. 2020;11:e00201. doi:10.14309/ctg.0000000000000201
   PubMed Web of Science ®Google Scholar
• Zhang L, Wu J, Ling MT, Zhao L, Zhao KN. The role of the PI3K/Akt/mTOR signalling pathway in human cancers induced by infection with human papillomaviruses. Mol Cancer. 2015;14:87. doi:10.1186/s12943-015-0361-x
   PubMed Web of Science ®Google Scholar
• Snietura M, Waniczek D, Piglowski W, et al. Potential role of human papilloma virus in the pathogenesis of gastric cancer. World J Gastroenterol. 2014;20:6632–6637. doi:10.3748/wjg.v20.i21.6632
   PubMed Web of Science ®Google Scholar
• Zhang R, Kim AS, Fox JM, et al. Mxra8 is a receptor for multiple arthritogenic alphaviruses. Nature. 2018;557:570–574. doi:10.1038/s41586-018-0121-3
   PubMed Web of Science ®Google Scholar
• Zhang R, Earnest JT, Kim AS, et al. Expression of the Mxra8 receptor promotes alphavirus infection and pathogenesis in mice and drosophila. Cell Rep. 2019;28:2647–2658 e2645. doi:10.1016/j.celrep.2019.07.105
   PubMed Web of Science ®Google Scholar
• Li S, Xu W. Mining TCGA database for screening and identification of hub genes in kidney renal clear cell carcinoma microenvironment. J Cell Biochem. 2020;21(8–9):3952–3960.
   Web of Science ®Google Scholar