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Original Research

Bioinformatic Exploration for Prognostic Significance of Sphingolipid Metabolism-Related Genes in Invasive Ductal Carcinoma Using the Cancer Genome Atlas Cohort

, ORCID Icon, & ORCID Icon
Pages 4423-4434 | Published online: 12 Aug 2021

References

  • DeSantis CE, Ma J, Goding Sauer A, Newman LA, Jemal A. Breast cancer statistics, 2017, racial disparity in mortality by state. CA Cancer J Clin. 2017;67(6):439–448. doi:10.3322/caac.21412
  • Makki J. Diversity of Breast Carcinoma: histological Subtypes and Clinical Relevance. Clin Med Insights Pathol. 2015;8:23–31. doi:10.4137/CPath.S31563
  • Sharma GN, Dave R, Sanadya J, Sharma P, Sharma KK. Various types and management of breast cancer: an overview. J Adv Pharm Technol Res. 2010;1(2):109–126.
  • Bundred NJ. Prognostic and predictive factors in breast cancer. Cancer Treat Rev. 2001;27(3):137–142. doi:10.1053/ctrv.2000.0207
  • Prat A, Pineda E, Adamo B, et al. Clinical implications of the intrinsic molecular subtypes of breast cancer. Breast. 2015;24(Suppl 2):S26–35. doi:10.1016/j.breast.2015.07.008
  • Wang Z, Jensen MA, Zenklusen JC. A Practical Guide to The Cancer Genome Atlas (TCGA). Methods Mol Biol. 2016;1418:111–141. doi:10.1007/978-1-4939-3578-9_6
  • Pralhada Rao R, Vaidyanathan N, Rengasamy M, Mammen Oommen A, Somaiya N, Jagannath MR. Sphingolipid metabolic pathway: an overview of major roles played in human diseases. J Lipids. 2013;2013:178910. doi:10.1155/2013/178910
  • Hannun YA, Obeid LM. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol. 2008;9(2):139–150. doi:10.1038/nrm2329
  • Erez-Roman R, Pienik R, Futerman AH. Increased ceramide synthase 2 and 6 mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression. Biochem Biophys Res Commun. 2010;391(1):219–223. doi:10.1016/j.bbrc.2009.11.035
  • Hartmann D, Lucks J, Fuchs S, et al. Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth. Int J Biochem Cell Biol. 2012;44(4):620–628. doi:10.1016/j.biocel.2011.12.019
  • Geffken K, Spiegel S. Sphingosine kinase 1 in breast cancer. Adv Biol Regul. 2018;67:59–65. doi:10.1016/j.jbior.2017.10.005
  • Acharya S, Yao J, Li P, et al. Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple-Negative Breast Cancer. Cancer Res. 2019;79(16):4211–4226. doi:10.1158/0008-5472.CAN-18-3803
  • Kochel TJ, Goloubeva OG, Fulton AM. Upregulation of Cyclooxygenase-2/Prostaglandin E2 (COX-2/PGE2) Pathway Member Multiple Drug Resistance-Associated Protein 4 (MRP4) and Downregulation of Prostaglandin Transporter (PGT) and 15-Prostaglandin Dehydrogenase (15-PGDH) in Triple-Negative Breast Cancer. Breast Cancer (Auckl). 2016;10:61–70. doi:10.4137/BCBCR.S38529
  • Ruckhaberle E, Rody A, Engels K, et al. Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer. Breast Cancer Res Treat. 2008;112(1):41–52. doi:10.1007/s10549-007-9836-9
  • de Hoon MJ, Imoto S, Nolan J, Miyano S. Open source clustering software. Bioinformatics. 2004;20(9):1453–1454. doi:10.1093/bioinformatics/bth078
  • Evans C, Hardin J, Stoebel DM. Selecting between-sample RNA-Seq normalization methods from the perspective of their assumptions. Brief Bioinform. 2018;19(5):776–792. doi:10.1093/bib/bbx008
  • Ogretmen B. Sphingolipid metabolism in cancer signalling and therapy. Nat Rev Cancer. 2018;18(1):33–50. doi:10.1038/nrc.2017.96
  • Friedman AA, Letai A, Fisher DE, Flaherty KT. Precision medicine for cancer with next-generation functional diagnostics. Nat Rev Cancer. 2015;15(12):747–756. doi:10.1038/nrc4015
  • Arnedos M, Vicier C, Loi S, et al. Precision medicine for metastatic breast cancer–limitations and solutions. Nat Rev Clin Oncol. 2015;12(12):693–704. doi:10.1038/nrclinonc.2015.123
  • Ahmadpour S, Noaparast Z, Abedi SM, Hosseinimehr SJ. (99m)Tc-(tricine)-HYNIC-Lys-FROP Peptide for Breast Tumor Targeting. Anticancer Agents Med Chem. 2018;18(9):1295–1302. doi:10.2174/1871520618666180307142027
  • Ahmadpour S, Noaparast Z, Abedi SM, Hosseinimehr SJ. (99m)Tc-HYNIC-(tricine/EDDA)-FROP peptide for MCF-7 breast tumor targeting and imaging. J Biomed Sci. 2018;25(1):17. doi:10.1186/s12929-018-0420-x
  • Ahmadpour S, Hosseinimehr SJ. Recent developments in peptide-based SPECT radiopharmaceuticals for breast tumor targeting. Life Sci. 2019;239:116870. doi:10.1016/j.lfs.2019.116870
  • Heinz LX, Baumann CL, Koberlin MS, et al. The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity. Cell Rep. 2015;11(12):1919–1928. doi:10.1016/j.celrep.2015.05.006
  • Yoo TH, Pedigo CE, Guzman J, et al. Sphingomyelinase-like phosphodiesterase 3b expression levels determine podocyte injury phenotypes in glomerular disease. J Am Soc Nephrol. 2015;26(1):133–147. doi:10.1681/ASN.2013111213
  • Mallela SK, Mitrofanova A, Merscher S, Fornoni A. Regulation of the amount of ceramide-1-phosphate synthesized in differentiated human podocytes. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864(12):158517. doi:10.1016/j.bbalip.2019.158517
  • Hait NC, Maiti A. The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer. Mediators Inflamm. 2017;2017:4806541. doi:10.1155/2017/4806541
  • Waldbillig F, Nitschke K, Abdelhadi A, et al. Phosphodiesterase SMPDL3B Gene Expression as Independent Outcome Prediction Marker in Localized Prostate Cancer. Int J Mol Sci. 2020;21(12):4373. doi:10.3390/ijms21124373
  • Yang D, Yang W, Zhang Q, Hu Y, Bao L, Damirin A. Migration of gastric cancer cells in response to lysophosphatidic acid is mediated by LPA receptor 2. Oncol Lett. 2013;5(3):1048–1052. doi:10.3892/ol.2013.1107
  • Onallah H, Davidson B, Reich R. Diverse Effects of Lysophosphatidic Acid Receptors on Ovarian Cancer Signaling Pathways. J Oncol. 2019;2019:7547469. doi:10.1155/2019/7547469
  • Lehtinen L, Vainio P, Wikman H, et al. 15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells. J Pathol. 2012;226(4):674–686. doi:10.1002/path.3956
  • Jang SW, Park WJ, Min H, et al. Altered mRNA expression levels of the major components of sphingolipid metabolism, ceramide synthases and their clinical implication in colorectal cancer. Oncol Rep. 2018;40(6):3489–3500. doi:10.3892/or.2018.6712