Serum Metabolomics of Tick-Borne Encephalitis Based on Orbitrap-Mass Spectrometry

References

• Zlobin VI, Pogodina VV, Kahl O. A brief history of the discovery of tick-borne encephalitis virus in the late 1930s (based on reminiscences of members of the expeditions, their colleagues, and relatives). Ticks Tick Borne Dis. 2017;8:813–820. doi:10.1016/j.ttbdis.2017.05.001
   PubMed Web of Science ®Google Scholar
• Ruzek D, Dobler G, Donoso Mantke O. Tick-borne encephalitis: pathogenesis and clinical implications. Travel Med Infect Dis. 2010;8:223–232. doi:10.1016/j.tmaid.2010.06.004
   PubMed Web of Science ®Google Scholar
• Bogovic P, Lusa L, Korva M, et al. Inflammatory immune responses in patients with tick-borne encephalitis: dynamics and association with the outcome of the disease. Microorganisms. 2019;7:514.
   PubMed Web of Science ®Google Scholar
• Yoshii K, Song JY, Park SB. Tick-borne encephalitis in Japan, Republic of Korea and China. Emerg Microbes Infect. 2017;6:e82.
   PubMed Web of Science ®Google Scholar
• Gerd W, Gisela W, Gross J. Studies on virus-specific nucleic acids synthesized in vertebrate and mosquito cells infected with flaviviruses. Virology. 1978;89:423–437. doi:10.1016/0042-6822(78)90185-X
   PubMed Web of Science ®Google Scholar
• Gritsun TS, Lashkevich VA, Gould EA. Tick-borne encephalitis. Antiviral Res. 2003;57:129–146. doi:10.1016/S0166-3542(02)00206-1
   PubMed Web of Science ®Google Scholar
• Chen J, Zhao X, Fritsche J, et al. Practical approach for the identification and isomer elucidation of biomarkers detected in a metabonomic study for the discovery of individuals at risk for diabetes by integrating the chromatographic and mass spectrometric information. Anal Chem. 2008;80:1280–1289. doi:10.1021/ac702089h
   PubMed Web of Science ®Google Scholar
• Reinhard K. The clinical and epidemiological profile of tick-borne encephalitis in southern Germany 1994-98: a prospective study of 656 patients. Brain. 1999;122:2067–2078. doi:10.1093/brain/122.11.2067
   PubMed Web of Science ®Google Scholar
• Johnson CH, Ivanisevic J, Siuzdak G. Metabolomics: beyond biomarkers and towards mechanisms. Nat Rev Mol Cell Biol. 2016;17(7):451–459. doi:10.1038/nrm.2016.25
   PubMed Web of Science ®Google Scholar
• Patti GJ, Yanes O, Siuzdak G. Innovation: metabolomics: the apogee of the omics trilogy. Nat Rev Mol Cell Biol. 2012;13:263–269. doi:10.1038/nrm3314
   PubMed Web of Science ®Google Scholar
• Oliver F. Metabolomics the link between genotypes and phenotypes. Plant Mol Biol. 2002;48:155–171. doi:10.1023/A:1013713905833
   PubMed Web of Science ®Google Scholar
• Lains I, Gantner M, Murinello S, et al. Metabolomics in the study of retinal health and disease. Prog Retin Eye Res. 2019;69:57–79. doi:10.1016/j.preteyeres.2018.11.002
   PubMed Web of Science ®Google Scholar
• Zullig T, Trotzmuller M, Kofeler HC. Lipidomics from sample preparation to data analysis: a primer. Anal Bioanal Chem. 2020;412:2191–2209. doi:10.1007/s00216-019-02241-y
   PubMed Web of Science ®Google Scholar
• Zhu Y, Li L, Zhang G, et al. Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2016;1033-1034:117–127. doi:10.1016/j.jchromb.2016.08.009
   PubMed Web of Science ®Google Scholar
• Adebayo AS, Mundhe SD, Awobode HO, et al. Metabolite profiling for biomarkers in Schistosoma haematobium infection and associated bladder pathologies. PLoS Negl Trop Dis. 2018;12:e0006452. doi:10.1371/journal.pntd.0006452
   PubMed Web of Science ®Google Scholar
• Wang Z, Li MY, Peng B, et al. GC-MS-based metabolome and metabolite regulation in serum-resistant Streptococcus agalactiae. J Proteome Res. 2016;15:2246–2253. doi:10.1021/acs.jproteome.6b00215
   PubMed Web of Science ®Google Scholar
• Du CC, Yang MJ, Li MY, et al. Metabolic mechanism for l-leucine-induced metabolome to eliminate Streptococcus iniae. J Proteome Res. 2017;16:1880–1889. doi:10.1021/acs.jproteome.6b00944
   PubMed Web of Science ®Google Scholar
• Du Y, Mi Z, Xie Y, et al. Insights into the molecular basis of tick-borne encephalitis from multiplatform metabolomics. PLoS Negl Trop Dis. 2021;15:e0009172. doi:10.1371/journal.pntd.0009172
   PubMed Web of Science ®Google Scholar
• Al-Mekhlafi A, Suhs KW, Schuchardt S, et al. Elevated free phosphatidylcholine levels in cerebrospinal fluid distinguish bacterial from viral CNS infections. Cells. 2021;10(5):1115. doi:10.3390/cells10051115
   PubMed Web of Science ®Google Scholar
• Ma N, Karam I, Liu XW, et al. UPLC-Q-TOF/MS-based urine and plasma metabonomics study on the ameliorative effects of aspirin eugenol ester in hyperlipidemia rats. Toxicol Appl Pharmacol. 2017;332:40–51. doi:10.1016/j.taap.2017.07.013
   PubMed Web of Science ®Google Scholar
• Chong J, Wishart DS, Xia J. Using MetaboAnalyst 4.0 for comprehensive and integrative metabolomics data analysis. Curr Protoc Bioinformatics. 2019;68:e86. doi:10.1002/cpbi.86
   PubMedGoogle Scholar
• Beale DJ, Oh DY, Karpe AV, et al. Untargeted metabolomics analysis of the upper respiratory tract of ferrets following influenza A virus infection and oseltamivir treatment. Metabolomics. 2019;15:33. doi:10.1007/s11306-019-1499-0
   PubMed Web of Science ®Google Scholar
• Jaaskelainen AJ, Korhonen EM, Huhtamo E, et al. Validation of serological and molecular methods for diagnosis of zika virus infections. J Virol Methods. 2019;263:68–74. doi:10.1016/j.jviromet.2018.10.011
   PubMed Web of Science ®Google Scholar
• Pasquier C, Joguet G, Mengelle C, et al. Kinetics of anti-ZIKV antibodies after Zika infection using two commercial enzyme-linked immunoassays. Diagn Microbiol Infect Dis. 2018;90:26–30. doi:10.1016/j.diagmicrobio.2017.09.001
   PubMed Web of Science ®Google Scholar
• Liu LL, Lin LR, Tong ML, et al. Incidence and risk factors for the prozone phenomenon in serologic testing for syphilis in a large cohort. Clin Infect Dis. 2014;59:384–389. doi:10.1093/cid/ciu325
   PubMed Web of Science ®Google Scholar
• Shen B, Yi X, Sun Y, et al. Proteomic and metabolomic characterization of COVID-19 patient sera. Cell. 2020;182:59–72 e15. doi:10.1016/j.cell.2020.05.032
   PubMed Web of Science ®Google Scholar
• Cui L, Hou J, Fang J, et al. Serum metabolomics investigation of humanized mouse model of dengue virus infection. J Virol. 2017;91:e00386.
   PubMed Web of Science ®Google Scholar
• Keshavarz M, Solaymani-Mohammadi F, Namdari H, et al. Metabolic host response and therapeutic approaches to influenza infection. Cell Mol Biol Lett. 2020;25:15. doi:10.1186/s11658-020-00211-2
   PubMed Web of Science ®Google Scholar
• Mathew A, Rothman AL. Understanding the contribution of cellular immunity to dengue disease pathogenesis. Immunol Rev. 2008;223:300–313. doi:10.1111/j.1600-065X.2008.00678.x
   PubMed Web of Science ®Google Scholar
• Liu Y, Hong Z, Tan G, et al. NMR and LC/MS-based global metabolomics to identify serum biomarkers differentiating hepatocellular carcinoma from liver cirrhosis. Int J Cancer. 2014;135:658–668. doi:10.1002/ijc.28706
   PubMed Web of Science ®Google Scholar
• Jia L, Wang C, Zhao S. Metabolomic identification of potential phospholipid biomarkers for chronic glomerulonephritis by using high performance liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2007;860:134–140. doi:10.1016/j.jchromb.2007.10.033
   PubMed Web of Science ®Google Scholar
• Lorizate M, Krausslich HG. Role of lipids in virus replication. Cold Spring Harb Perspect Biol. 2011;3:a004820. doi:10.1101/cshperspect.a004820
   PubMed Web of Science ®Google Scholar
• Bagam P, Singh DP, Inda ME. Unraveling the role of membrane microdomains during microbial infections. Cell Biol Toxicol. 2017;33:429–455.
   PubMed Web of Science ®Google Scholar
• Taube S, Jiang M, Wobus CE. Glycosphingolipids as receptors for non-enveloped viruses. Viruses. 2010;2(4):1011–1049. doi:10.3390/v2041011
   PubMed Web of Science ®Google Scholar
• Marsh M, Helenius A. Virus entry: open sesame. Cell. 2006;124(4):729–740. doi:10.1016/j.cell.2006.02.007
   PubMed Web of Science ®Google Scholar
• Mercer J, Helenius A. Virus entry by macropinocytosis. Nat Cell Biol. 2009;11:510–520. doi:10.1038/ncb0509-510
   PubMed Web of Science ®Google Scholar
• Gualdoni GA, Mayer KA, Kapsch AM, et al. Rhinovirus induces an anabolic reprogramming in host cell metabolism essential for viral replication. Proc Natl Acad Sci USA. 2018;115:E7158–E7165. doi:10.1073/pnas.1800525115
   PubMed Web of Science ®Google Scholar
• Nagy PD, Strating JR, Kuppeveld F Building viral replication organelles: close encounters of the membrane types. PLoS Pathog. 2016;12:e1005912. doi:10.1371/journal.ppat.1005912
   PubMed Web of Science ®Google Scholar
• Hsu NY, Ilnytska O, Belov G, et al. Viral reorganization of the secretory pathway generates distinct organelles for RNA replication. Cell. 2010;141:799–811. doi:10.1016/j.cell.2010.03.050
   PubMed Web of Science ®Google Scholar
• Diamond DL, Syder AJ, Jacobs JM, et al. Temporal proteome and lipidome profiles reveal hepatitis C virus-associated reprogramming of hepatocellular metabolism and bioenergetics. PLoS Pathog. 2010;6:e1000719. doi:10.1371/journal.ppat.1000719
   PubMed Web of Science ®Google Scholar
• Ono A, Ablan SD, Lockett SJ. Phosphatidylinositol (4,5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane. Proc Natl Acad Sci. 2004;101:14889–14894. doi:10.1073/pnas.0405596101
   PubMed Web of Science ®Google Scholar
• Zhang J, Pekosz A, Lamb RA. Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins. J Virol Methods. 2000;74:4634–4644. doi:10.1128/JVI.74.10.4634-4644.2000
   Web of Science ®Google Scholar
• Jangi S, Otterbein L, Robson S. The molecular basis for the immunomodulatory activities of unconjugated bilirubin. Int J Biochem Cell Biol. 2013;45:2843–2851. doi:10.1016/j.biocel.2013.09.014
   PubMed Web of Science ®Google Scholar
• Schwertner A, Jackson WG, Tolan G. Association of low serum concentration of bilirubin with increased risk of coronary artery disease. Clin Chem. 1994;40(1):18–23. doi:10.1093/clinchem/40.1.18
   PubMed Web of Science ®Google Scholar
• Wu Ben J, Chen K, Barter Philip J. Niacin inhibits vascular inflammation via the induction of heme oxygenase-1. Circulation. 2012;125:150–158. doi:10.1161/CIRCULATIONAHA.111.053108
   PubMed Web of Science ®Google Scholar