A Novel Pyroptosis-Related Gene Signature for Early-Stage Lung Squamous Cell Carcinoma

References

• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. doi:10.3322/caac.21492
   PubMed Web of Science ®Google Scholar
• Chien CM, Yang JC, Wu PH, et al. Phytochemical naphtho[1,2-b] furan-4,5-dione induced topoisomerase II-mediated DNA damage response in human non-small-cell lung cancer. Phytomedicine. 2019;54:109–119. doi:10.1016/j.phymed.2018.06.025
   PubMed Web of Science ®Google Scholar
• Fang Y, Tian S, Pan Y, et al. Pyroptosis: a new frontier in cancer. Biomed Pharmacother. 2020;121:109595. doi:10.1016/j.biopha.2019.109595
   PubMed Web of Science ®Google Scholar
• Shi J, Gao W, Shao F. Pyroptosis: gasdermin-mediated programmed necrotic cell death. Trends Biochem Sci. 2017;42(4):245–254. doi:10.1016/j.tibs.2016.10.004
   PubMed Web of Science ®Google Scholar
• Liu X, Zhang Z, Ruan J, et al. Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Nature. 2016;535(7610):153–158. doi:10.1038/nature18629
   PubMed Web of Science ®Google Scholar
• Kovacs SB, Miao EA. Gasdermins: effectors of pyroptosis. Trends Cell Biol. 2017;27(9):673–684. doi:10.1016/j.tcb.2017.05.005
   PubMed Web of Science ®Google Scholar
• Wang Y, Gao W, Shi X, et al. Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin. Nature. 2017;547(7661):99–103. doi:10.1038/nature22393
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Vitale I, Abrams JM, et al. Molecular definitions of cell death subroutines: recommendations of the nomenclature committee on cell death 2012. Cell Death Differ. 2012;19(1):107–120. doi:10.1038/cdd.2011.96
   PubMed Web of Science ®Google Scholar
• Dupaul-Chicoine J, Yeretssian G, Doiron K, et al. Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity. 2010;32(3):367–378. doi:10.1016/j.immuni.2010.02.012
   PubMed Web of Science ®Google Scholar
• Sakaizawa T, Matsumura T, Fujii C, et al. Potential role of ASC, a proapoptotic protein, for determining the cisplatin susceptibility of lung cancer cells. Tohoku J Exp Med. 2018;244(2):133–144. doi:10.1620/tjem.244.133
   PubMed Web of Science ®Google Scholar
• Tang R, Xu J, Zhang B, et al. Ferroptosis, necroptosis, and pyroptosis in anticancer immunity. J Hematol Oncol. 2020;13(1):110.
   PubMed Web of Science ®Google Scholar
• Zhang D, Xiao Y, Luo J, et al. Measurement of fractional exhaled nitric oxide and nasal nitric oxide in male patients with obstructive sleep apnea. Sleep Breath. 2019;23(3):785–793. doi:10.1007/s11325-018-1760-1
   PubMed Web of Science ®Google Scholar
• Aki T, Funakoshi T, Noritake K, Unuma K, Uemura K. Extracellular glucose is crucially involved in the fate decision of LPS-stimulated RAW264.7 murine macrophage cells. Sci Rep. 2020;10(1):10581. doi:10.1038/s41598-020-67396-6
   PubMed Web of Science ®Google Scholar
• Senju H, Kumagai A, Nakamura Y, et al. Effect of IL-18 on the expansion and phenotype of human natural killer cells: application to cancer immunotherapy. Int J Biol Sci. 2018;14(3):331–340. doi:10.7150/ijbs.22809
   PubMed Web of Science ®Google Scholar
• Noro R, Ishigame T, Walsh N, et al. A two-gene prognostic classifier for early-stage lung squamous cell carcinoma in multiple large-scale and geographically diverse cohorts. J Thorac Oncol. 2017;12(1):65–76. doi:10.1016/j.jtho.2016.08.141
   PubMed Web of Science ®Google Scholar
• Karki R, Kanneganti TD. Diverging inflammasome signals in tumorigenesis and potential targeting. Nat Rev Cancer. 2019;19(4):197–214. doi:10.1038/s41568-019-0123-y
   PubMed Web of Science ®Google Scholar
• Xia X, Wang X, Cheng Z, et al. The role of pyroptosis in cancer: pro-cancer or pro-”host”? Cell Death Dis. 2019;10(9):650. doi:10.1038/s41419-019-1883-8
   PubMed Web of Science ®Google Scholar
• Wang B, Yin Q. AIM2 inflammasome activation and regulation: a structural perspective. J Struct Biol. 2017;200(3):279–282. doi:10.1016/j.jsb.2017.08.001
   PubMed Web of Science ®Google Scholar
• Man SM, Kanneganti TD. Regulation of inflammasome activation. Immunol Rev. 2015;265(1):6–21. doi:10.1111/imr.12296
   PubMed Web of Science ®Google Scholar
• Ishwaran H, Gerds TA, Kogalur UB, et al. Random survival forests for competing risks. Biostatistics. 2014;15(4):757–773. doi:10.1093/biostatistics/kxu010
   PubMed Web of Science ®Google Scholar
• Dalwadi H, Krysan K, Heuze-Vourc’h N, et al. Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer. Clin Cancer Res. 2005;11(21):7674–7682. doi:10.1158/1078-0432.CCR-05-1205
   PubMed Web of Science ®Google Scholar
• Yamaguchi T, Yamamoto Y, Yokota S, et al. Involvement of interleukin-6 in the elevation of plasma fibrinogen levels in lung cancer patients. Jpn J Clin Oncol. 1998;28(12):740–744. doi:10.1093/jjco/28.12.740
   PubMed Web of Science ®Google Scholar
• Velloso FJ, Campos AR, Sogayar MC, Correa RG. Proteome profiling of triple negative breast cancer cells overexpressing NOD1 and NOD2 receptors unveils molecular signatures of malignant cell proliferation. BMC Genomics. 2019;20(1):152. doi:10.1186/s12864-019-5523-6
   PubMed Web of Science ®Google Scholar
• Guo XX, Li XP, Zhou P, et al. Evodiamine induces apoptosis in SMMC-7721 and HepG2 cells by suppressing NOD1 signal pathway. Int J Mol Sci. 2018;19(11):3419. doi:10.3390/ijms19113419
   PubMed Web of Science ®Google Scholar
• Wang S, Yang J, Li X, et al. Discovery of 1,4-Benzodiazepine-2,5-dione (BZD) derivatives as dual nucleotide binding oligomerization domain containing 1/2 (NOD1/NOD2) antagonists sensitizing paclitaxel (PTX) to suppress Lewis Lung Carcinoma (LLC) growth in vivo. J Med Chem. 2017;60(12):5162–5192. doi:10.1021/acs.jmedchem.7b00608
   PubMed Web of Science ®Google Scholar
• Liu R, Truax AD, Chen L, et al. Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components. Oncotarget. 2015;6(32):33456–33469. doi:10.18632/oncotarget.5587
   PubMedGoogle Scholar
• Wang Y. Mechanism of pemetrexed combined with oxaliplatin in regulating NOD1/NF-Kb/R1P2 signlingin lung cancer. China J Modern Med. 2019;29(19):53–57.
   Google Scholar
• Lin XY, Choi MS, Porter AG. Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma. J Biol Chem. 2000;275(51):39920–39926. doi:10.1074/jbc.M007255200
   PubMed Web of Science ®Google Scholar
• Shi J, Zhao Y, Wang Y, et al. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature. 2014;514(7521):187–192. doi:10.1038/nature13683
   PubMed Web of Science ®Google Scholar
• Raymond AA, Mechin MC, Nachat R, et al. Nine procaspases are expressed in normal human epidermis, but only caspase-14 is fully processed. Br J Dermatol. 2007;156(3):420–427. doi:10.1111/j.1365-2133.2006.07656.x
   PubMed Web of Science ®Google Scholar
• Lagrange B, Benaoudia S, Wallet P, et al. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11. Nat Commun. 2018;9(1):242. doi:10.1038/s41467-017-02682-y
   PubMed Web of Science ®Google Scholar
• Sonnenschein C, Soto AM. The death of the cancer cell. Cancer Res. 2011;71(13):4334–4337. doi:10.1158/0008-5472.CAN-11-0639
   PubMed Web of Science ®Google Scholar
• He C, Yang J, Jiang X, et al. Kaempferol alleviates LPS-ATP mediated inflammatory injury in splenic lymphocytes via regulation of the pyroptosis pathway in mice. Immunopharmacol Immunotoxicol. 2019;41(5):538–548. doi:10.1080/08923973.2019.1666405
   PubMed Web of Science ®Google Scholar
• Wolf D, Wolf AM, Rumpold H, et al. The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer. Clin Cancer Res. 2005;11(23):8326–8331. doi:10.1158/1078-0432.CCR-05-1244
   PubMed Web of Science ®Google Scholar
• Toker A, Nguyen LT, Stone SC, et al. Regulatory T cells in ovarian cancer are characterized by a highly activated phenotype distinct from that in melanoma. Clin Cancer Res. 2018;24(22):5685–5696. doi:10.1158/1078-0432.CCR-18-0554
   PubMed Web of Science ®Google Scholar
• Saito T, Nishikawa H, Wada H, et al. Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers. Nat Med. 2016;22(6):679–684. doi:10.1038/nm.4086
   PubMed Web of Science ®Google Scholar