A Pan-Cancer Analysis of the Role of Selenoprotein P mRNA in Tumorigenesis

References

• Lu J, Holmgren A. Selenoproteins. J Biol Chem. 2009;284(2):723–727.
   PubMed Web of Science ®Google Scholar
• Papp LV, Lu J, Holmgren A, Khanna KK. From selenium to selenoproteins: synthesis, identity, and their role in human health. Antioxid Redox Signal. 2007;9(7):775–806.
   PubMed Web of Science ®Google Scholar
• Kang D, Lee J, Wu C, et al. The role of selenium metabolism and selenoproteins in cartilage homeostasis and arthropathies. Exp Mol Med. 2020;52(8):1198–1208.
   PubMed Web of Science ®Google Scholar
• Burk RF, Hill KE, Motley AK. Selenoprotein metabolism and function: evidence for more than one function for selenoprotein P. J Nutr. 2003;133(5):1517S–1520S.
   PubMed Web of Science ®Google Scholar
• Hatfield DL, Berry MJ, Gladyshev VN. Selenium: Its Molecular Biology and Role in Human Health. Springer Science & Business Media; 2011.
   Google Scholar
• Rayman MP. Selenium in cancer prevention: a review of the evidence and mechanism of action. Proc Nutr Soc. 2005;64(4):527–542.
   PubMed Web of Science ®Google Scholar
• Kuršvietienė L, Mongirdienė A, Bernatonienė J, Šulinskienė J, Stanevičienė I. Selenium anticancer properties and impact on cellular redox status. Antioxidants (Basel). 2020;9:1.
   Google Scholar
• Amaral AFS, Cantor KP, Silverman DT, Malats N. Selenium and bladder cancer risk: a meta-analysis. Cancer Epidemiol Biomark Prev. 2010;19(9):2407–2415.
   PubMed Web of Science ®Google Scholar
• Glattre E, Thomassen Y, Thoresen SO, et al. Prediagnostic serum selenium in a case-control study of thyroid cancer. Int J Epidemiol. 1989;18(1):45–49.
   PubMed Web of Science ®Google Scholar
• Wei W-Q, Abnet CC, Qiao Y-L, et al. Prospective study of serum selenium concentrations and esophageal and gastric cardia cancer, heart disease, stroke, and total death. Am J Clin Nutr. 2004;79(1):80–85.
   PubMed Web of Science ®Google Scholar
• Navarro-Alarcon M, Cabrera-Vique C. Selenium in food and the human body: a review. Sci Total Environ. 2008;400(1–3):115–141.
   PubMed Web of Science ®Google Scholar
• Wu W, Li D, Feng X, et al. A pan-cancer study of selenoprotein genes as promising targets for cancer therapy. BMC Med Genomics. 2021;14(1):78.
   PubMed Web of Science ®Google Scholar
• Stolwijk JM, Garje R, Sieren JC, Buettner GR, Zakharia Y. Understanding the redox biology of selenium in the search of targeted cancer therapies. Antioxidants (Basel). 2020;9:5.
   Google Scholar
• Short SP, Whitten-Barrett C, Williams CS. Selenoprotein P in colitis-associated carcinoma. Mol Cell Oncol. 2016;3(3):e1075094.
   PubMed Web of Science ®Google Scholar
• Hill KE, Wu S, Motley AK, et al. Production of selenoprotein P (Sepp1) by hepatocytes is central to selenium homeostasis. J Biol Chem. 2012;287(48):40414–40424.
   PubMed Web of Science ®Google Scholar
• Schweizer U, Streckfuss F, Pelt P, et al. Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supply. Biochem J. 2005;386(Pt 2):221–226.
   PubMed Web of Science ®Google Scholar
• Gresner P, Gromadzinska J, Jablonska E, Kaczmarski J, Wasowicz W. Expression of selenoprotein-coding genes SEPP1, SEP15 and hGPX1 in non-small cell lung cancer. Lung Cancer. 2009;65(1):34–40.
   PubMed Web of Science ®Google Scholar
• Gonzalez-Moreno O, Boque N, Redrado M, et al. Selenoprotein-P is down-regulated in prostate cancer, which results in lack of protection against oxidative damage. Prostate. 2011;71(8):824–834.
   PubMed Web of Science ®Google Scholar
• Barrett CW, Reddy VK, Short SP, et al. Selenoprotein P influences colitis-induced tumorigenesis by mediating stemness and oxidative damage. J Clin Invest. 2015;125(7):2646–2660.
   PubMed Web of Science ®Google Scholar
• Murai K, Honda M, Shirasaki T, et al. Induction of selenoprotein P mRNA during hepatitis C virus infection inhibits RIG-I-mediated antiviral immunity. Cell Host Microbe. 2019;25(4):588–601.e587.
   PubMed Web of Science ®Google Scholar
• Tang Z, Kang B, Li C, Chen T, Zhang Z. GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis. Nucleic Acids Res. 2019;47(W1):W556–W560.
   PubMed Web of Science ®Google Scholar
• Chen F, Chandrashekar DS, Varambally S, Creighton CJ. Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers. Nat Commun. 2019;10(1):5679.
   PubMed Web of Science ®Google Scholar
• Gao J, Aksoy BA, Dogrusoz U, et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal. 2013;6(269):pl1.
   PubMed Web of Science ®Google Scholar
• Yarchoan M, Hopkins A, Jaffee EM. Tumor mutational burden and response rate to PD-1 inhibition. N Engl J Med. 2017;377(25):2500–2501.
   PubMed Web of Science ®Google Scholar
• Li K, Luo H, Huang L, Luo H, Zhu X. Microsatellite instability: a review of what the oncologist should know. Cancer Cell Int. 2020;20:16.
   PubMed Web of Science ®Google Scholar
• Dan H, Zhang S, Zhou Y, Guan Q. DNA methyltransferase inhibitors: catalysts for antitumour immune responses. Onco Targets Ther. 2019;12:10903–10916.
   PubMed Web of Science ®Google Scholar
• Li T, Fan J, Wang B, et al. TIMER: a web server for comprehensive analysis of tumor-infiltrating immune cells. Cancer Res. 2017;77(21):e108–e110.
   PubMed Web of Science ®Google Scholar
• Patel S, Leal AD, Gorski DH. The homeobox gene Gax inhibits angiogenesis through inhibition of nuclear factor-kappaB-dependent endothelial cell gene expression. Cancer Res. 2005;65(4):1414–1424.
   PubMed Web of Science ®Google Scholar
• Whanger PD. Selenium and its relationship to cancer: an update. Br J Nutr. 2004;91(1):11–28.
   PubMed Web of Science ®Google Scholar
• Drutel A, Archambeaud F, Caron P. Selenium and the thyroid gland: more good news for clinicians. Clin Endocrinol (Oxf). 2013;78(2):155–164.
   PubMed Web of Science ®Google Scholar
• Chen Y-C, Prabhu KS, Mastro AM. Is selenium a potential treatment for cancer metastasis? Nutrients. 2013;5(4):1149–1168.
   PubMed Web of Science ®Google Scholar
• Burk RF, Hill KE, Motley AK. Selenoprotein metabolism and function: evidence for more than one function for selenoprotein P. J Nutr. 2003;133(5Suppl 1):1517S–1520S.
   PubMedGoogle Scholar
• Olson GE, Winfrey VP, Nagdas SK, Hill KE, Burk RF. Apolipoprotein E receptor-2 (ApoER2) mediates selenium uptake from selenoprotein P by the mouse testis. J Biol Chem. 2007;282(16):12290–12297.
   PubMed Web of Science ®Google Scholar
• Burk RF, Hill KE, Motley AK, et al. Selenoprotein P and apolipoprotein E receptor-2 interact at the blood-brain barrier and also within the brain to maintain an essential selenium pool that protects against neurodegeneration. FASEB J. 2014;28(8):3579–3588.
   PubMed Web of Science ®Google Scholar
• Olson GE, Winfrey VP, Hill KE, Burk RF. Megalin mediates selenoprotein P uptake by kidney proximal tubule epithelial cells. J Biol Chem. 2008;283(11):6854–6860.
   PubMed Web of Science ®Google Scholar
• Calvo A, Xiao N, Kang J, et al. Alterations in gene expression profiles during prostate cancer progression: functional correlations to tumorigenicity and down-regulation of selenoprotein-P in mouse and human tumors. Cancer Res. 2002;62(18):5325–5335.
   PubMed Web of Science ®Google Scholar
• Al-Taie OH, Uceyler N, Eubner U, et al. Expression profiling and genetic alterations of the selenoproteins GI-GPx and SePP in colorectal carcinogenesis. Nutr Cancer. 2004;48:1.
   PubMed Web of Science ®Google Scholar
• Murawaki Y, Tsuchiya H, Kanbe T, et al. Aberrant expression of selenoproteins in the progression of colorectal cancer. Cancer Lett. 2008;259(2):218–230.
   PubMed Web of Science ®Google Scholar
• Hughes DJ, Duarte-Salles T, Hybsier S, et al. Prediagnostic selenium status and hepatobiliary cancer risk in the European prospective investigation into cancer and nutrition cohort. Am J Clin Nutr. 2016;104(2):406–414.
   PubMed Web of Science ®Google Scholar
• Meyer HA, Endermann T, Stephan C, et al. Selenoprotein P status correlates to cancer-specific mortality in renal cancer patients. PLoS One. 2012;7(10):e46644.
   PubMed Web of Science ®Google Scholar
• Short SP, Williams CS. Selenoproteins in tumorigenesis and cancer progression. Adv Cancer Res. 2017;136:49–83.
   PubMed Web of Science ®Google Scholar
• Sato N, Fukushima N, Chang R, Matsubayashi H, Goggins M. Differential and epigenetic gene expression profiling identifies frequent disruption of the RELN pathway in pancreatic cancers. Gastroenterology. 2006;130(2):548–565.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Zhou Y, Schweizer U, et al. Comparative analysis of selenocysteine machinery and selenoproteome gene expression in mouse brain identifies neurons as key functional sites of selenium in mammals. J Biol Chem. 2008;283(4):2427–2438.
   PubMed Web of Science ®Google Scholar
• Yue C, Shan Z, Tan Y, et al. His-rich domain of selenoprotein P ameliorates neuropathology and cognitive deficits by regulating TrkB pathway and zinc homeostasis in an Alzheimer model of mice. ACS Chem Neurosci. 2020;11(24):4098–4110.
   PubMed Web of Science ®Google Scholar
• Solovyev N, Drobyshev E, Bjørklund G, Dubrovskii Y, Lysiuk R, Rayman MP. Selenium, selenoprotein P, and Alzheimer’s disease: is there a link? Free Radic Biol Med. 2018;127:124–133.
   PubMed Web of Science ®Google Scholar
• Hoffmann PR, Berry MJ. The influence of selenium on immune responses. Mol Nutr Food Res. 2008;52(11):1273–1280.
   PubMed Web of Science ®Google Scholar
• Barrett CW, Singh K, Motley AK, et al. Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis. PLoS One. 2013;8(7):e67845.
   PubMed Web of Science ®Google Scholar
• Yi Y-S, Park SG, Byeon SM, Kwon Y-G, Jung G. Hepatitis B virus X protein induces TNF-alpha expression via down-regulation of selenoprotein P in human hepatoma cell line, HepG2. Biochim Biophys Acta. 2003;1638(3):249–256.
   PubMed Web of Science ®Google Scholar
• Cat B, Stuhlmann D, Steinbrenner H, et al. Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species. J Cell Sci. 2006;119(Pt 13):2727–2738.
   PubMed Web of Science ®Google Scholar
• Bosschaerts T, Guilliams M, Noel W, et al. Alternatively activated myeloid cells limit pathogenicity associated with African trypanosomiasis through the IL-10 inducible gene selenoprotein P. J Immunol. 2008;180(9):6168–6175.
   PubMed Web of Science ®Google Scholar
• Short SP, Pilat JM, Williams CS. Roles for selenium and selenoprotein P in the development, progression, and prevention of intestinal disease. Free Radic Biol Med. 2018;127:26–35.
   PubMed Web of Science ®Google Scholar
• Speckmann B, Bidmon H-J, Borchardt A, Sies H, Steinbrenner H. Intestinal selenoprotein P in epithelial cells and in plasma cells. Arch Biochem Biophys. 2014;541:30–36.
   PubMed Web of Science ®Google Scholar
• Richman EL, Chan JM. Selenium and prostate cancer: the puzzle isn’t finished yet. Am J Clin Nutr. 2012;96(1):1–2.
   PubMed Web of Science ®Google Scholar
• Pohl NM, Tong C, Fang W, Bi X, Li T, Yang W. Transcriptional regulation and biological functions of selenium-binding protein 1 in colorectal cancer in vitro and in nude mouse xenografts. PLoS One. 2009;4(11):e7774.
   PubMed Web of Science ®Google Scholar
• Streicher KL, Sylte MJ, Johnson SE, Sordillo LM. Thioredoxin reductase regulates angiogenesis by increasing endothelial cell-derived vascular endothelial growth factor. Nutr Cancer. 2004;50(2):221–231.
   PubMed Web of Science ®Google Scholar
• Lu J, Jiang C. Antiangiogenic activity of selenium in cancer chemoprevention: metabolite-specific effects. Nutr Cancer. 2001;40(1):64–73.
   PubMed Web of Science ®Google Scholar