Novel Ferroptosis-Related Multigene Prognostic Models for Patients with Bladder Cancer

References

• Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–249. doi:10.3322/caac.21660
   PubMed Web of Science ®Google Scholar
• Miller KD, Siegel RL, Lin CC, et al. Cancer treatment and survivorship statistics, 2016. CA Cancer J Clin. 2016;66(4):271–289. doi:10.3322/caac.21349
   PubMed Web of Science ®Google Scholar
• Miller KD, Nogueira L, Mariotto AB, et al. Cancer treatment and survivorship statistics, 2019. CA Cancer J Clin. 2019;69(5):363–385. doi:10.3322/caac.21565
   PubMed Web of Science ®Google Scholar
• Dixon SJ, Lemberg K, Lamprecht M, et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012;149(5):1060–1072. doi:10.1016/j.cell.2012.03.042
   PubMed Web of Science ®Google Scholar
• Li J, Cao F, Yin H-L, et al. Ferroptosis: past, present and future. Cell Death Dis. 2020;11(2):88. doi:10.1038/s41419-020-2298-2
   PubMed Web of Science ®Google Scholar
• Mou Y, Wang J, Wu J, et al. Ferroptosis, a new form of cell death: opportunities and challenges in cancer. J Hematol Oncol. 2019;12(1):34. doi:10.1186/s13045-019-0720-y
   PubMed Web of Science ®Google Scholar
• Louandre C, Marcq I, Bouhlal H, et al. The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells. Cancer Lett. 2015;356(2):971–977. doi:10.1016/j.canlet.2014.11.014
   PubMed Web of Science ®Google Scholar
• Xie Y, Zhu S, Song X, et al. The tumor suppressor p53 limits ferroptosis by blocking DPP4 activity. Cell Rep. 2017;20(7):1692–1704. doi:10.1016/j.celrep.2017.07.055
   PubMed Web of Science ®Google Scholar
• Chen M-S, Wang S-F, Hsu C-Y, et al. CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway. Oncotarget. 2017;8(70):114588–114602. doi:10.18632/oncotarget.23055
   PubMedGoogle Scholar
• Miess H, Dankworth B, Gouw AM, et al. The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma. Oncogene. 2018;37(40):5435–5450. doi:10.1038/s41388-018-0315-z
   PubMed Web of Science ®Google Scholar
• Liu J, Ma H, Meng L, et al. Construction and external validation of a ferroptosis-related gene signature of predictive value for the overall survival in bladder cancer. Front Mol Biosci. 2021;8:675651. doi:10.3389/fmolb.2021.675651
   PubMed Web of Science ®Google Scholar
• Sun J, Yue W, You J, et al. Identification of a novel ferroptosis-related gene prognostic signature in bladder cancer. Front Oncol. 2021;11:730716. doi:10.3389/fonc.2021.730716
   PubMed Web of Science ®Google Scholar
• Yan Y, Cai J, Huang Z, et al. A novel ferroptosis-related prognostic signature reveals macrophage infiltration and EMT Status in bladder cancer. Front Cell Dev Biol. 2021;9:712230. doi:10.3389/fcell.2021.712230
   PubMed Web of Science ®Google Scholar
• Yang L, Li C, Qin Y, et al. A novel prognostic model based on ferroptosis-related gene signature for bladder cancer. Front Oncol. 2021;11:686044. doi:10.3389/fonc.2021.686044
   PubMed Web of Science ®Google Scholar
• Liang Y, Ye F, Xu C, et al. A novel survival model based on a Ferroptosis-related gene signature for predicting overall survival in bladder cancer. BMC Cancer. 2021;21(1):943. doi:10.1186/s12885-021-08687-7
   PubMed Web of Science ®Google Scholar
• Zhang M, Zhang X, Yu M, et al. A novel ferroptosis-related gene model for overall survival predictions of bladder urothelial carcinoma patients. Front Oncol. 2021;11:698856. doi:10.3389/fonc.2021.698856
   PubMed Web of Science ®Google Scholar
• Luan J-C, Zeng T-Y, Zhang Q-J, et al. A novel signature constructed by ferroptosis-associated genes (FAGs) for the prediction of prognosis in bladder urothelial carcinoma (BLCA) and associated with immune infiltration. Cancer Cell Int. 2021;21(1):414. doi:10.1186/s12935-021-02096-3
   PubMed Web of Science ®Google Scholar
• Liang J-Y, Wang D-S, Lin H-C, et al. A novel ferroptosis-related gene signature for overall survival prediction in patients with Hepatocellular Carcinoma. Int J Biol Sci. 2020;16(13):2430–2441. doi:10.7150/ijbs.45050
   PubMed Web of Science ®Google Scholar
• Wang W, Green M, Choi JE, et al. CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy. Nature. 2019;569(7755):270–274. doi:10.1038/s41586-019-1170-y
   PubMed Web of Science ®Google Scholar
• Stockwell BR, Friedmann Angeli JP, Bayir H, et al. Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease. Cell. 2017;171(2):273–285. doi:10.1016/j.cell.2017.09.021
   PubMed Web of Science ®Google Scholar
• Liang C, Zhang X, Yang M, Dong X. Recent progress in ferroptosis inducers for cancer therapy. Adv Mater. 2019;31(51):e1904197. doi:10.1002/adma.201904197
   PubMed Web of Science ®Google Scholar
• Eagle H. The specific amino acid requirements of a human carcinoma cell (Strain Hela) in tissue culture. J Exp Med. 1955;102(1):37–48. doi:10.1084/jem.102.1.37
   PubMed Web of Science ®Google Scholar
• Dolma S, Lessnick SL, Hahn WC, Stockwell BR. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. Cancer Cell. 2003;3(3):285–296. doi:10.1016/s1535-6108(03)00050-3
   PubMed Web of Science ®Google Scholar
• Yang WS, Stockwell BR. Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells. Chem Biol. 2008;15:234–245. doi:10.1016/j.chembiol.2008.02.010
   PubMedGoogle Scholar
• Yagoda N, von Rechenberg M, Zaganjor E, et al. RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels. Nature. 2007;447(7146):864–868. doi:10.1038/nature05859
   PubMed Web of Science ®Google Scholar
• Fagerberg L, Hallström BM, Oksvold P, et al. Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Mol Cell Proteomics. 2014;13(2):397–406. doi:10.1074/mcp.M113.035600
   PubMed Web of Science ®Google Scholar
• Tan L, Sha L, Hou N, et al. High α B-crystallin and p53 co-expression is associated with poor prognosis in ovarian cancer. Biosci Rep. 2019;39(6). doi:10.1042/bsr20182407
   Web of Science ®Google Scholar
• Feng H, Schorpp K, Jin J, et al. Transferrin receptor is a specific ferroptosis marker. Cell Rep. 2020;30(10):3411–3423e3417. doi:10.1016/j.celrep.2020.02.049
   PubMed Web of Science ®Google Scholar
• Chen L, Vasoya RP, Toke NH, et al. HNF4 regulates fatty acid oxidation and is required for renewal of intestinal stem cells in mice. Gastroenterology. 2020;158(4):985–999e989. doi:10.1053/j.gastro.2019.11.031
   PubMed Web of Science ®Google Scholar
• Thommen DS, Schumacher TN. T cell dysfunction in cancer. Cancer Cell. 2018;33(4):547–562. doi:10.1016/j.ccell.2018.03.012
   PubMed Web of Science ®Google Scholar
• Khan O, Giles JR, McDonald S, et al. TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion. Nature. 2019;571(7764):211–218. doi:10.1038/s41586-019-1325-x
   PubMed Web of Science ®Google Scholar
• Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646–674. doi:10.1016/j.cell.2011.02.013
   PubMed Web of Science ®Google Scholar
• Musa J, Aynaud MM, Mirabeau O, Delattre O, Grünewald TG. MYBL2 (B-Myb): a central regulator of cell proliferation, cell survival and differentiation involved in tumorigenesis. Cell Death Dis. 2017;8:e2895. doi:10.1038/cddis.2017.244
   PubMed Web of Science ®Google Scholar
• Nord H, Segersten U, Sandgren J, et al. Focal amplifications are associated with high grade and recurrences in stage Ta bladder carcinoma. Int J Cancer. 2010;126:1390–1402. doi:10.1002/ijc.24954
   PubMed Web of Science ®Google Scholar
• Mun JY, Baek S-W, Park WY, et al. E2F1 promotes progression of bladder cancer by modulating RAD54L involved in homologous recombination repair. Int J Mol Sci. 2020;21(23):9025. doi:10.3390/ijms21239025
   PubMed Web of Science ®Google Scholar