99
Views
1
CrossRef citations to date
0
Altmetric
Original Research

Expression and Clinical Significance of Origin Recognition Complex Subunit 6 in Breast Cancer – A Comprehensive Bioinformatics Analysis

, , , , , & show all
Pages 9733-9745 | Published online: 14 Dec 2021

References

  • Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–249. doi:10.3322/caac.21660
  • Cardoso F, Fallowfield L, Costa A, Castiglione M, Senkus E. Locally recurrent or metastatic breast cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2011;22(Suppl 6):vi25–vi30. doi:10.1093/annonc/mdr372
  • Suo HD, Tao Z, Zhang L, et al. Coexpression network analysis of genes related to the characteristics of tumor stemness in triple-negative breast cancer. BioMed Res Int. 2020;2020:7575862. doi:10.1155/2020/7575862
  • Koleck TA, Conley YP. Identification and prioritization of candidate genes for symptom variability in breast cancer survivors based on disease characteristics at the cellular level. Breast Cancer. 2016;8:29–37. doi:10.2147/BCTT.S88434
  • Bell SP, Dutta A. DNA replication in eukaryotic cells. Ann Rev Biochem. 2002;71:333–374. doi:10.1146/annurev.biochem.71.110601.135425
  • Prasanth SG, Shen Z, Prasanth KV, Stillman B. Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization. Proc Natl Acad Sci. 2010;107(34):15093–15098. doi:10.1073/pnas.1009945107
  • Prasanth SG, Prasanth KV, Stillman B. Orc6 involved in DNA replication, chromosome segregation, and cytokinesis. Science. 2002;297(5583):1026–1031. doi:10.1126/science.1072802
  • Dhar SK, Yoshida K, Machida Y, et al. Replication from oriP of Epstein-Barr virus requires human ORC and is inhibited by geminin. Cell. 2001;106(3):287–296. doi:10.1016/S0092-8674(01)00458-5
  • Kordon MM, Szczurek A, Berniak K, et al. PML-like subnuclear bodies, containing XRCC1, juxtaposed to DNA replication-based single-strand breaks. FASEB J. 2019;33(2):2301–2313. doi:10.1096/fj.201801379R
  • Koleck TA, Bender CM, Clark BZ, et al. An exploratory study of host polymorphisms in genes that clinically characterize breast cancer tumors and pretreatment cognitive performance in breast cancer survivors. Breast Cancer. 2017;9:95–110. doi:10.2147/BCTT.S123785
  • El-Saghire H, Vandevoorde C, Ost P, et al. Intensity modulated radiotherapy induces pro-inflammatory and pro-survival responses in prostate cancer patients. Int J Oncol. 2014;44(4):1073–1083. doi:10.3892/ijo.2014.2260
  • Xiong W, Xie C, Qiu Y, Tu Z, Gong Q. Origin recognition complex subunit 1 regulates cell growth and metastasis in glioma by altering activation of ERK and JNK signaling pathway. Mol Cell Probes. 2020;49:101496. doi:10.1016/j.mcp.2019.101496
  • Liu Y, Chen P, Li M, et al. Comprehensive analysis of the control of cancer stem cell characteristics in endometrial cancer by network analysis. Comput Math Methods Med. 2021;2021:6653295. doi:10.1155/2021/6653295
  • Gavin EJ, Song B, Wang Y, Xi Y, Ju J. Reduction of Orc6 expression sensitizes human colon cancer cells to 5-fluorouracil and cisplatin. PLoS One. 2008;3(12):e4054. doi:10.1371/journal.pone.0004054
  • Xi Y, Formentini A, Nakajima G, Kornmann M, Ju J. Validation of biomarkers associated with 5-fluorouracil and thymidylate synthase in colorectal cancer. Oncol Rep. 2008;19(1):257–262.
  • Hu Y, Wang L, Li Z, et al. Potential prognostic and diagnostic values of CDC6, CDC45, ORC6 and SNHG7 in colorectal cancer. Onco Targets Ther. 2019;12:11609–11621. doi:10.2147/OTT.S231941
  • Mao R, Wang Z, Zhang Y, et al. Development and validation of a novel prognostic signature in gastric adenocarcinoma. Aging. 2020;12(21):22233–22252. doi:10.18632/aging.104161
  • Zhou W, Li J, Lu X, et al. Derivation and validation of a prognostic model for cancer dependency genes based on CRISPR-Cas9 in gastric adenocarcinoma. Fron Oncol. 2021;11:617289. doi:10.3389/fonc.2021.617289
  • Wang XK, Wang QQ, Huang JL, et al. Novel candidate biomarkers of origin recognition complex 1, 5 and 6 for survival surveillance in patients with hepatocellular carcinoma. J Cancer. 2020;11(7):1869–1882. doi:10.7150/jca.39163
  • Nangraj AS, Selvaraj G, Kaliamurthi S, Kaushik AC, Cho WC, Wei DQ. Integrated PPI- and WGCNA-retrieval of hub gene signatures shared between Barrett’s esophagus and esophageal adenocarcinoma. Front Pharmacol. 2020;11:881. doi:10.3389/fphar.2020.00881
  • Zhang Y, Tseng JT, Lien IC, Li F, Wu W, Li H. mRNAsi index: machine learning in mining lung adenocarcinoma stem cell biomarkers. Genes. 2020;11(3):257.
  • Song B, Liu XS, Rice SJ, et al. Plk1 phosphorylation of orc2 and hbo1 contributes to gemcitabine resistance in pancreatic cancer. Mol Cancer Ther. 2013;12(1):58–68. doi:10.1158/1535-7163.MCT-12-0632
  • Kim SH, Ho JN, Jin H, et al. Upregulated expression of BCL2, MCM7, and CCNE1 indicate cisplatin-resistance in the set of two human bladder cancer cell lines: T24 cisplatin sensitive and T24R2 cisplatin resistant bladder cancer cell lines. Invest Clin Urol. 2016;57(1):63–72. doi:10.4111/icu.2016.57.1.63
  • Ősz Á, Lánczky A, Győrffy B. Survival analysis in breast cancer using proteomic data from four independent datasets. Sci Rep. 2021;11(1):16787. doi:10.1038/s41598-021-96340-5
  • Chandrashekar DS, Bashel B, Balasubramanya SAH, et al. UALCAN: a portal for facilitating tumor subgroup gene expression and survival analyses. Neoplasia. 2017;19(8):649–658. doi:10.1016/j.neo.2017.05.002
  • Liu J, Lichtenberg T, Hoadley KA, et al. An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics. Cell. 2018;173(2):400–416.e411. doi:10.1016/j.cell.2018.02.052
  • Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA. 2005;102(43):15545–15550. doi:10.1073/pnas.0506580102
  • Hänzelmann S, Castelo R, Guinney J. GSVA: gene set variation analysis for microarray and RNA-seq data. BMC Bioinform. 2013;14:7. doi:10.1186/1471-2105-14-7
  • Deepak KGK, Vempati R, Nagaraju GP, et al. Tumor microenvironment: challenges and opportunities in targeting metastasis of triple negative breast cancer. Pharmacol Res. 2020;153:104683. doi:10.1016/j.phrs.2020.104683
  • Mittal S, Brown NJ, Holen I. The breast tumor microenvironment: role in cancer development, progression and response to therapy. Expert Rev Mol Diagn. 2018;18(3):227–243. doi:10.1080/14737159.2018.1439382
  • Stanton SE, Disis ML. Clinical significance of tumor-infiltrating lymphocytes in breast cancer. J Immunother Cancer. 2016;4:59. doi:10.1186/s40425-016-0165-6
  • Noël G, Langouo Fontsa M, Garaud S, et al. Functional Th1-oriented T follicular helper cells that infiltrate human breast cancer promote effective adaptive immunity. J Clin Invest. 2021;131(19):e139905. doi:10.1172/JCI139905
  • Teschendorff AE, Gomez S, Arenas A, et al. Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules. BMC Cancer. 2010;10:604. doi:10.1186/1471-2407-10-604
  • Ghirelli C, Reyal F, Jeanmougin M, et al. Breast cancer cell-derived GM-CSF licenses regulatory Th2 induction by plasmacytoid predendritic cells in aggressive disease subtypes. Cancer Res. 2015;75(14):2775–2787. doi:10.1158/0008-5472.CAN-14-2386
  • Bates GJ, Fox SB, Han C, et al. Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J Clin Oncol. 2006;24(34):5373–5380. doi:10.1200/JCO.2006.05.9584
  • Aponte-López A, Fuentes-Pananá EM, Cortes-Muñoz D, Muñoz-Cruz S. Mast cell, the neglected member of the tumor microenvironment: role in breast cancer. J Immunol Res. 2018;2018:2584243. doi:10.1155/2018/2584243
  • Majorini MT, Cancila V, Rigoni A, et al. Infiltrating mast cell-mediated stimulation of estrogen receptor activity in breast cancer cells promotes the luminal phenotype. Cancer Res. 2020;80(11):2311–2324. doi:10.1158/0008-5472.CAN-19-3596
  • Della Rovere F, Granata A, Familiari D, D’Arrigo G, Mondello B, Basile G. Mast cells in invasive ductal breast cancer: different behavior in high and minimum hormone-receptive cancers. Anticancer Res. 2007;27(4b):2465–2471.
  • Bottos A, Gotthardt D, Gill JW, et al. Decreased NK-cell tumour immunosurveillance consequent to JAK inhibition enhances metastasis in breast cancer models. Nat Commun. 2016;7:12258. doi:10.1038/ncomms12258