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Original Research

Diagnostic Utility of TLE1 (Transducer-Like Enhancer of Split 1) in Distinguishing Synovial Sarcoma from Mimicking Tumors

, , ORCID Icon, &
Pages 9173-9179 | Published online: 01 Dec 2021

References

  • Thway K, Fisher C. Synovial sarcoma: defining features and diagnostic evolution. Ann Diagn Pathol. 2014;18:369–380. doi:10.1016/j.anndiagpath.2014.09.002
  • Fisher C. Synovial sarcoma. Ann Diagn Pathol. 1998;2:401–421. doi:10.1016/S1092-9134(98)80042-7
  • Bhurgri Y, Bhurgri H, Pervez S, et al. Epidemiology of soft tissue sarcomas in Karachi South, Pakistan (1995-7). Asian Pac J Cancer Prev. 2008;9:709–714.
  • Cadman NL, Soule EH, Kelly PJ. Synovial sarcoma; an analysis of 134 tumors. Cancer. 1965;18(5):613–627. doi:10.1002/1097-0142(196505)18:5<613::aid-cncr2820180510>3.0.co;2-v
  • WHO Classification of Tumours Editorial Board. Soft tissue and bone tumours. Lyon (France): International Agency for Research on Cancer; 2020. Accessed November 11, 2021. Available from: https://publications.iarc.fr/588.
  • Su L, Sampaio AV, Jones KB, et al. Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics. Cancer Cell. 2012;21:333–347. doi:10.1016/j.ccr.2012.01.010
  • Terry J, Saito T, Subramanian S, et al. TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies. Am J Surg Pathol. 2007;31:240–246. doi:10.1097/01.pas.0000213330.71745.39
  • Fisher C. Immunohistochemistry in diagnosis of soft tissue tumors. Histopathology. 2011;58:1001–1012. doi:10.1111/j.1365-2559.2010.03707.x
  • Jain S, Xu R, Prieto VG, Lee P. Molecular classification of soft tissue sarcomas and its clinical applications. Int J Clin Exp Pathol. 2010;3:416–428.
  • Qureshi MB, Uddin N, Tariq M, Raheem A, Pervez S. Frequency of transducer-like enhancer of split 1 immunohistochemical expression in synovial sarcoma: an institution-based cross-sectional study. Cureus. 2019;11:6357. doi:10.7759/cureus.6357
  • Vlenterie M, Hillebrandt-Roeffen MH, Flucke UE, et al. Next generation sequencing in synovial sarcoma reveals novel gene mutations. Oncotarget. 2015;6:34680–34690. doi:10.18632/oncotarget.5786
  • El Beaino M, Jupiter DC, Assi T, et al. Diagnostic value of TLE1 in synovial sarcoma: a systematic review and meta-analysis. Sarcoma. 2020;2020:1–6. doi:10.1155/2020/7192347
  • Knosel T, Heretsch S, Altendorf-Hofmann A, et al. TLE1 is a robust diagnostic biomarker for synovial sarcomas and correlates with t(X; 18): analysis of 319 cases. Eur J Cancer. 2010;46:1170–1176. doi:10.1016/j.ejca.2010.01.032
  • Foo WC, Cruise MW, Wick MR, Hornick JL. Immunohistochemical staining for TLE1 distinguishes synovial sarcoma from histologic mimics. Am J Clin Pathol. 2011;135:839–844. doi:10.1309/AJCP45SSNAOPXYXU
  • Jagdis A, Rubin BP, Tubbs RR, Pacheco M, Nielsen TO. Prospective evaluation of TLE1 as a diagnostic immunohistochemical marker in synovial sarcoma. Am J Surg Pathol. 2009;33:1743–1751. doi:10.1097/PAS.0b013e3181b7ed36
  • Chuang HC, Hsu SC, Huang CG, Hsueh S, Ng KF, Chen TC. Reappraisal of TLE-1 immunohistochemical staining and molecular detection of SS18-SSX fusion transcripts for synovial sarcoma. Pathol Int. 2013;63:573–580. doi:10.1111/pin.12113