295
Views
4
CrossRef citations to date
0
Altmetric
Original Research

Risk Factors for Length of Hospital Stay in Acute Exacerbation Chronic Obstructive Pulmonary Disease: A Multicenter Cross-Sectional Study

, ORCID Icon, , , , ORCID Icon, , , & ORCID Icon show all
Pages 3447-3458 | Published online: 29 Mar 2022

References

  • Wang H, Naghavi M, Allen C. A systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1459–1544. doi:10.1016/S0140-6736(16)31012-1
  • Vogelmeier CF, Criner GJ, Martinez FJ, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report: GOLD Executive Summary. Eur Respir J. 2017;49(3):1700214. doi:10.1183/13993003.00214-2017
  • (GOLD). GIfCLD. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (Revised 2020). Available from: https://goldcopdorg/gold-reports/2020. Accessed March 18, 2022.
  • Ozkaya S, Findik S, Atici AG. The costs of hospitalization in patients with acute exacerbation of chronic obstructive pulmonary disease. Clinicoecon Outcomes Res. 2011;3:15–18. doi:10.2147/CEOR.S14820
  • Alshabanat A, Otterstatter MC, Sin DD, et al. Impact of a COPD comprehensive case management program on hospital length of stay and readmission rates. Int J Chron Obstruct Pulmon Dis. 2017;12:961–971. doi:10.2147/COPD.S124385
  • Ko FWS, Chan KP, Ngai J, et al. Blood eosinophil count as a predictor of hospital length of stay in COPD exacerbations. Respirology. 2020;25(3):259–266. doi:10.1111/resp.13660
  • Milan S, Bondalapati P, Megally M, et al. Positive expiratory pressure therapy with and without oscillation and hospital length of stay for acute exacerbation of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2019;14:2553–2561. doi:10.2147/copd.S213546
  • Genao L, Durheim MT, Mi X, Todd JL, Whitson HE, Curtis LH. Early and long-term outcomes of older adults after acute care encounters for chronic obstructive pulmonary disease exacerbation. Ann Am Thorac Soc. 2015;12(12):1805–1812. doi:10.1513/AnnalsATS.201504-250OC
  • You L, Niu H, Huang K, Dong F, Yang T, Wang C. Clinical features and outcomes of acute exacerbation in chronic obstructive pulmonary disease patients with pulmonary heart disease: a multicenter observational study. Int J Chron Obstruct Pulmon Dis. 2021;16:2901–2910. doi:10.2147/copd.S325925
  • Iheanacho I, Zhang S, King D, Rizzo M, Ismaila AS. Economic burden of Chronic Obstructive Pulmonary Disease (COPD): a Systematic Literature Review. Int J Chron Obstruct Pulmon Dis. 2020;15:439–460. doi:10.2147/copd.S234942
  • Torabipour A, Hakim A, Ahmadi Angali K, Dolatshah M, Yusofzadeh M. Cost analysis of hospitalized patients with chronic obstructive pulmonary disease: a State-Level Cross-Sectional Study. Tanaffos. 2016;15(2):75–82.
  • Li F, Sun Z, Li H, Yang T, Shi Z. Factors associated with hospitalisation costs in patients with chronic obstructive pulmonary disease. Int J Tuberc Lung Dis. 2018;22(4):458–463. doi:10.5588/ijtld.17.0430
  • Sin DD, Stafinski T, Ng YC, Bell NR, Jacobs P. The impact of chronic obstructive pulmonary disease on work loss in the United States. Am J Respir Crit Care Med. 2002;165(5):704–707. doi:10.1164/ajrccm.165.5.2104055
  • Koul PA, Nowshehr AA, Khan UH, Jan RA, Shah SU. Cost of severe chronic obstructive pulmonary disease exacerbations in a High Burden Region in North India. Ann Glob Health. 2019;85(1). doi:10.5334/aogh.2423
  • Dalal AA, Christensen L, Liu F, Riedel AA. Direct costs of chronic obstructive pulmonary disease among managed care patients. Int J Chron Obstruct Pulmon Dis. 2010;5:341–349. doi:10.2147/COPD.S13771
  • Chen YH, Yao WZ, Cai BQ, et al. Economic analysis in admitted patients with acute exacerbation of chronic obstructive pulmonary disease. Chin Med J (Engl). 2008;121(7):587–591. doi:10.1097/00029330-200804010-00003
  • Tsimogianni AM, Papiris SA, Stathopoulos GT, Manali ED, Roussos C, Kotanidou A. Predictors of outcome after exacerbation of chronic obstructive pulmonary disease. J Gen Intern Med. 2009;24(9):1043–1048. doi:10.1007/s11606-009-1061-2
  • Limsuwat C, Mankongpaisarnrung C, Dumrongmongcolgul N, Nugent K. Factors influencing the length of hospital stay in patients with acute exacerbations of chronic obstructive pulmonary disease admitted to intensive care units. Qual Manag Health Care. 2014;23(2):86–93. doi:10.1097/qmh.0000000000000024
  • Mushlin AI, Black ER, Connolly CA, Buonaccorso KM, Eberly SW. The necessary length of hospital stay for chronic pulmonary disease. JAMA. 1991;266(1):80–83. doi:10.1001/jama.1991.03470010084035
  • Agboado G, Peters J, Donkin L. Factors influencing the length of hospital stay among patients resident in Blackpool admitted with COPD: a cross-sectional study. BMJ Open. 2012;2(5):e000869. doi:10.1136/bmjopen-2012-000869
  • Crisafulli E, Ielpo A, Barbeta E, et al. Clinical variables predicting the risk of a hospital stay for longer than 7 days in patients with severe acute exacerbations of chronic obstructive pulmonary disease: a prospective study. Respir Res. 2018;19(1):261. doi:10.1186/s12931-018-0951-4\]
  • Wang Y, Stavem K, Dahl FA, Humerfelt S, Haugen T. Factors associated with a prolonged length of stay after acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Int J Chron Obstruct Pulmon Dis. 2014;9:99–105. doi:10.2147/COPD.S51467
  • Quintana JM, Unzurrunzaga A, Garcia-Gutierrez S, et al. Predictors of hospital length of stay in patients with exacerbations of COPD: a Cohort Study. J Gen Intern Med. 2015;30(6):824–831. doi:10.1007/s11606-014-3129-x.
  • World Medical Association. Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013;310(20):2191–2194. doi:10.1001/jama.2013.281053
  • Bartlett JG, Dowell SF, Mandell LA, File TM Jr, Musher DM, Fine MJ. Practice guidelines for the management of community-acquired pneumonia in adults. Infectious Diseases Society of America. Clin Infect Dis. 2000;31(2):347–382. doi:10.1086/313954
  • Lim WS, Woodhead M. British Thoracic Society adult community acquired pneumonia audit 2009/10. Thorax. 2011;66(6):548–549. doi:10.1136/thoraxjnl-2011-200081
  • Dai G, Ran Y, Wang J, et al. Clinical differences between eosinophilic and noneosinophilic acute exacerbation of chronic obstructive pulmonary disease: a Multicenter Cross-Sectional Study. Mediators of Inflammation. 2020;2020:1059079. doi:10.1155/2020/1059079
  • Cao B, Huang Y, She DY, et al. Diagnosis and treatment of community-acquired pneumonia in adults: 2016 clinical practice guidelines by the Chinese Thoracic Society, Chinese Medical Association. Clin Respir J. 2018;12(4):1320–1360. doi:10.1111/crj.12674
  • Claessens YE, Debray MP, Tubach F, et al. Early chest computed tomography scan to assist diagnosis and guide treatment decision for suspected community-acquired pneumonia. Am J Respir Crit Care Med. 2015;192(8):974–982. doi:10.1164/rccm.201501-0017OC
  • Flateau C, Le Bel J, Tubiana S, et al. High heterogeneity in community-acquired pneumonia inclusion criteria: does this impact on the validity of the results of randomized controlled trials? BMC Infect Dis. 2018;18(1):607. doi:10.1186/s12879-018-3515-9
  • Shujaat A, Minkin R, Eden E. Pulmonary hypertension and chronic cor pulmonale in COPD. Int J Chron Obstruct Pulmon Dis. 2007;2(3):273–282.
  • Park SY, Lee CY, Kim C, et al. One-year prognosis and the role of brain natriuretic peptide levels in patients with chronic cor pulmonale. J Korean Med Sci. 2015;30(4):442–449. doi:10.3346/jkms.2015.30.4.442
  • Berry CE, Wise RA. Mortality in COPD: causes, risk factors, and prevention. COPD. 2010;7(5):375–382. doi:10.3109/15412555.2010.510160
  • Inabnit LS, Blanchette C, Ruban C. Comorbidities and length of stay in chronic obstructive pulmonary disease patients. COPD. 2018;15(4):355–360. doi:10.1080/15412555.2018.1513470
  • Harries TH, Thornton HV, Crichton S, Schofield P, Gilkes A, White PT. Length of stay of COPD hospital admissions between 2006 and 2010: a retrospective longitudinal study. Int J Chron Obstruct Pulmon Dis. 2015;10:603–611. doi:10.2147/copd.S77092
  • Engel B, Schindler C, Leuppi JD, Rutishauser J. Predictors of re-exacerbation after an index exacerbation of chronic obstructive pulmonary disease in the REDUCE randomised clinical trial. Swiss Med Wkly. 2017;147:w14439. doi:10.4414/smw.2017.14439
  • Li LS, Caughey G, Johnston K. Comorbidity associated with referral to pulmonary rehabilitation in people hospitalized with chronic obstructive pulmonary disease. J Cardiopulm Rehabil Prev. 2014;34(6):430–436. doi:10.1097/HCR.0000000000000080
  • Barnes PJ, Celli BR. Systemic manifestations and comorbidities of COPD. Eur Respir J. 2009;33(5):1165–1185. doi:10.1183/09031936.00128008
  • Mortensen EM, Copeland LA, Pugh MJ, et al. Impact of statins and ACE inhibitors on mortality after COPD exacerbations. Respir Res. 2009;10(1):45. doi:10.1186/1465-9921-10-45
  • Abusaid GH, Barbagelata A, Tuero E, Mahmood A, Sharma G. Diastolic dysfunction and COPD exacerbation. Postgrad Med. 2009;121(4):76–81. doi:10.3810/pgm.2009.07.2033
  • Divo M, Cote C, de Torres JP, et al. Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2012;186(2):155–161. doi:10.1164/rccm.201201-0034OC
  • Wells JM, Washko GR, Han MK, et al. Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med. 2012;367(10):913–921. doi:10.1056/NEJMoa1203830
  • Caramori G, Casolari P, Barczyk A, Durham AL, Di Stefano A, Adcock I. COPD immunopathology. Semin Immunopathol. 2016;38(4):497–515. doi:10.1007/s00281-016-0561-5
  • Rahimirad S, Ghaffary MR, Rahimirad MH, Rashidi F. Association between admission neutrophil to lymphocyte ratio and outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease. Tuberk Toraks. 2017;65(1):25–31. doi:10.5578/tt.27626
  • Gómez-Rosero JA, Cáceres-Galvis C, Ascuntar J, Atencia C, Vallejo CE, Jaimes F. Biomarkers as a prognostic factor in COPD exacerbation: a Cohort Study. COPD. 2021;18(3):325–332. doi:10.1080/15412555.2021.1922370
  • Aksoy E, Karakurt Z, Gungor S, et al. Neutrophil to lymphocyte ratio is a better indicator of COPD exacerbation severity in neutrophilic endotypes than eosinophilic endotypes. Int J Chron Obstruct Pulmon Dis. 2018;13:2721–2730. doi:10.2147/copd.S170353
  • Lu FY, Chen R, Li N, et al. Neutrophil-to-lymphocyte ratio predicts clinical outcome of severe acute exacerbation of COPD in frequent exacerbators. Int J Chron Obstruct Pulmon Dis. 2021;16:341–349. doi:10.2147/copd.S290422
  • Taylan M, Demir M, Kaya H, et al. Alterations of the neutrophil-lymphocyte ratio during the period of stable and acute exacerbation of chronic obstructive pulmonary disease patients. Clin Respir J. 2017;11(3):311–317. doi:10.1111/crj.12336