MicroRNA Let-7i Regulates Innate TLR4 Pathways in Peripheral Blood Mononuclear Cells of Patients with Ankylosing Spondylitis

References

• Brown MA, Kenna T, Wordsworth BP. Genetics of ankylosing spondylitis--insights into pathogenesis. Nat Rev Rheumatol. 2016;12(2):81–91. doi:10.1038/nrrheum.2015.133
   PubMed Web of Science ®Google Scholar
• Simone D, Al Mossawi MH, Bowness P. Progress in our understanding of the pathogenesis of ankylosing spondylitis. Rheumatology. 2018;57(suppl_6):vi4–vi9. doi:10.1093/rheumatology/key001
   PubMedGoogle Scholar
• Bond D. Ankylosing spondylitis: diagnosis and management. Nurs Stand. 2013;28(16–18):52–9; quiz 60. doi:10.7748/ns2013.12.28.16.52.e7807
   PubMedGoogle Scholar
• Smith JA. Update on ankylosing spondylitis: current concepts in pathogenesis. Curr Allergy Asthma Rep. 2015;15(1):489. doi:10.1007/s11882-014-0489-6
   PubMed Web of Science ®Google Scholar
• Babaie F, Hasankhani M, Mohammadi H, et al. The role of gut microbiota and IL-23/IL-17 pathway in ankylosing spondylitis immunopathogenesis: new insights and updates. Immunol Lett. 2018;196:52–62. doi:10.1016/j.imlet.2018.01.014
   PubMed Web of Science ®Google Scholar
• Jethwa H, Bowness P. The interleukin (IL)-23/IL-17 axis in ankylosing spondylitis: new advances and potentials for treatment. Clin Exp Immunol. 2016;183(1):30–36. doi:10.1111/cei.12670
   PubMed Web of Science ®Google Scholar
• Michonneau D, Latis E, Curis E, et al. Metabolomics analysis of human acute graft-versus-host disease reveals changes in host and microbiota-derived metabolites. Nat Commun. 2019;10(1):5695. doi:10.1038/s41467-019-13498-3
   PubMed Web of Science ®Google Scholar
• Koupenova M, Clancy L, Corkrey HA, Freedman JE. Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis. Circ Res. 2018;122(2):337–351. doi:10.1161/circresaha.117.310795
   PubMed Web of Science ®Google Scholar
• Oliveira-Toré CF, Moraes AG, Martinez GF, et al. Genetic polymorphisms of toll-like receptors 2 and 9 as susceptibility factors for the development of ankylosing spondylitis and psoriatic arthritis. J Immunol Res. 2019;2019:1492092. doi:10.1155/2019/1492092
   PubMed Web of Science ®Google Scholar
• Aletaha S, Haddad L, Roozbehkia M, et al. M2000 (β-D-Mannuronic Acid) as a novel antagonist for blocking the TLR2 and TLR4 downstream signalling pathway. Scand J Immunol. 2017;85(2):122–129. doi:10.1111/sji.12519
   PubMed Web of Science ®Google Scholar
• Mitchell S, Mercado EL, Adelaja A, et al. An NFκB activity calculator to delineate signaling crosstalk: type I and II interferons enhance NFκB via distinct mechanisms. Front Immunol. 2019;10:1425. doi:10.3389/fimmu.2019.01425
   PubMed Web of Science ®Google Scholar
• Li M, He Y, Zhou Z, et al. MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6-p47(phox)-oxidative stress pathway in neutrophils. Gut. 2017;66(4):705–715. doi:10.1136/gutjnl-2016-311861
   PubMed Web of Science ®Google Scholar
• Schildberg FA, Klein SR, Freeman GJ, Sharpe AH. Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family. Immunity. 2016;44(5):955–972. doi:10.1016/j.immuni.2016.05.002
   PubMed Web of Science ®Google Scholar
• Pauley KM, Chan EK. MicroRNAs and their emerging roles in immunology. Ann N Y Acad Sci. 2008;1143:226–239. doi:10.1196/annals.1443.009
   PubMed Web of Science ®Google Scholar
• Reyes-Loyola P, Rodríguez-Henríquez P, Ballinas-Verdugo MA, et al. Plasma let-7i, miR-16, and miR-221 levels as candidate biomarkers for the assessment of ankylosing spondylitis in Mexican patients naïve to anti-TNF therapy. Clin Rheumatol. 2019;38(5):1367–1373. doi:10.1007/s10067-019-04509-1
   PubMed Web of Science ®Google Scholar
• Najm A, Blanchard F, Le Goff B. Micro-RNAs in inflammatory arthritis: from physiopathology to diagnosis, prognosis and therapeutic opportunities. Biochem Pharmacol. 2019;165:134–144. doi:10.1016/j.bcp.2019.02.031
   PubMed Web of Science ®Google Scholar
• Li Z, Wong SH, Shen J, Chan MTV, Wu WKK. The role of MicroRNAS in ankylosing spondylitis. Medicine. 2016;95(14):e3325. doi:10.1097/md.0000000000003325
   PubMed Web of Science ®Google Scholar
• Yang W, Yan X, Xia Q, et al. Predisposition of six well-characterized microRNAs to syndesmophytes among Chinese patients with ankylosing spondylitis. Mod Rheumatol. 2019;29(1):173–180. doi:10.1080/14397595.2018.1453277
   PubMed Web of Science ®Google Scholar
• Zochling J. Measures of symptoms and disease status in ankylosing spondylitis: Ankylosing Spondylitis Disease Activity Score (ASDAS), Ankylosing Spondylitis Quality of Life Scale (ASQoL), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Global Score (BAS-G), Bath Ankylosing Spondylitis Metrology Index (BASMI), Dougados Functional Index (DFI), and Health Assessment Questionnaire for the Spondylarthropathies (HAQ-S). Arthritis Care Res. 2011;63(Suppl 11):S47–58. doi:10.1002/acr.20575
   PubMed Web of Science ®Google Scholar
• Cui H, Xie N, Tan Z, et al. The human long noncoding RNA lnc-IL7R regulates the inflammatory response. Eur J Immunol. 2014;44(7):2085–2095. doi:10.1002/eji.201344126
   PubMed Web of Science ®Google Scholar
• Coronnello C, Benos PV. ComiR: combinatorial microRNA target prediction tool. Nucleic Acids Res. 2013;41(WebServer issue):W159–W164. doi:10.1093/nar/gkt379
   PubMedGoogle Scholar
• Vanaki N, Aslani S, Jamshidi A, Mahmoudi M. Role of innate immune system in the pathogenesis of ankylosing spondylitis. Biomed Pharmacother. 2018;105:130–143. doi:10.1016/j.biopha.2018.05.097
   PubMed Web of Science ®Google Scholar
• Nahid MA, Satoh M, Chan EK. MicroRNA in TLR signaling and endotoxin tolerance. Cell Mol Immunol. 2011;8(5):388–403. doi:10.1038/cmi.2011.26
   PubMed Web of Science ®Google Scholar
• Kragstrup TW, Andersen T, Holm C, et al. Toll-like receptor 2 and 4 induced interleukin-19 dampens immune reactions and associates inversely with spondyloarthritis disease activity. Clin Exp Immunol. 2015;180(2):233–242. doi:10.1111/cei.12577
   PubMed Web of Science ®Google Scholar
• Wang H, Sun N, Li K, Tian J, Li J. Assay of peripheral regulatory Vδ1 T cells in ankylosing spondylitis and its significance. Med Sci Monit. 2016;22:3163–3168. doi:10.12659/msm.897126
   PubMed Web of Science ®Google Scholar
• Detassis S, Grasso M, Del Vescovo V, Denti MA. microRNAs make the call in cancer personalized medicine. Front Cell Dev Biol. 2017;5:86. doi:10.3389/fcell.2017.00086
   PubMed Web of Science ®Google Scholar
• Janský L, Reymanová P, Kopecký J. Dynamics of cytokine production in human peripheral blood mononuclear cells stimulated by LPS or infected by Borrelia. Physiol Res. 2003;52(6):593–598.
   Web of Science ®Google Scholar