Advanced search
Publication Cover
International Journal of General Medicine Volume 16, 2023 - Issue
Submit an article Journal homepage
359
Views
2
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Immunohistochemical Expression of IDH1, ATRX, Ki67, GFAP, and Prognosis in Indonesian Glioma Patients

Dody Priambada1 Department of Neurosurgery, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, IndonesiaView further author information
,
Muhamad Thohar Arifin1 Department of Neurosurgery, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, IndonesiaCorrespondence[email protected]
View further author information
,
Abdi Saputro1 Department of Neurosurgery, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, IndonesiaView further author information
,
Azka Muzakka1 Department of Neurosurgery, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, IndonesiaView further author information
,
Vega Karlowee2 Department of Clinical Pathology, Faculty of Medicine, Diponegoro University, Dr. Kariadi Hospital, Semarang, IndonesiaView further author information
,
Udadi Sadhana2 Department of Clinical Pathology, Faculty of Medicine, Diponegoro University, Dr. Kariadi Hospital, Semarang, IndonesiaView further author information
,
Yuriz Bakhtiar1 Department of Neurosurgery, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, IndonesiaView further author information
,
Krisna Tsaniadi Prihastomo1 Department of Neurosurgery, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, IndonesiaORCID Iconhttps://orcid.org/0000-0002-0792-2943View further author information
ORCID Icon,
Ajid Risdianto1 Department of Neurosurgery, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, IndonesiaView further author information
,
Happy Kurnia Brotoarianto1 Department of Neurosurgery, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, IndonesiaView further author information
,
Erie Andar1 Department of Neurosurgery, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, IndonesiaView further author information
&
Zainal Muttaqin1 Department of Neurosurgery, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, IndonesiaORCID Iconhttps://orcid.org/0000-0002-9054-1809View further author information
ORCID Icon show all
Pages 393-403 | Received 01 Dec 2022, Accepted 07 Jan 2023, Published online: 01 Feb 2023

References

  • Nobusawa S, Watanabe T, Kleihues P, Ohgaki H. IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas. Clin Cancer Res. 2009;15:19. doi:10.1158/1078-0432.CCR-09-0715
  • Yan H, Parsons DW, Jin G, et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med. 2009;360(8):765–773. doi:10.1056/NEJMoa0808710
  • Mondesir J, Willekens C, Touat M, de Botton S. IDH1 and IDH2 mutations as novel therapeutic targets: current perspectives. J Blood Med. 2016;7:171–180. doi:10.2147/JBM.S70716
  • Whitfield BT, Huse JT. Classification of adult-type diffuse gliomas: impact of the World Health Organization 2021 update. Brain Pathol. 2022;32(4). doi:10.1111/bpa.13062
  • Leeper HE, Caron AA, Decker PA, Jenkins RB, Lachance DH, Giannini C. IDH mutation, 1p19q codeletion and ATRX loss in WHO grade II gliomas. Oncotarget. 2015;6(30):30295–30305. doi:10.18632/oncotarget.4497
  • Ellor SV, Pagano-Young TA, Avgeropoulos NG. Glioblastoma: background, standard treatment paradigms, and supportive care considerations. J Law Med Ethics. 2014;42(2):171–182. doi:10.1111/jlme.12133
  • Ostrom QT, Gittleman H, Xu J, et al. CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2009–2013. Neuro Oncol. 2016;18:v1–v75. doi:10.1093/neuonc/now207
  • Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol. 2013;200(4):373–383. doi:10.1083/jcb.201211138
  • Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68(1):7–30. doi:10.3322/caac.21442
  • Schwab DE, Lepski G, Borchers C, Trautmann K, Paulsen F, Schittenhelm J. Immunohistochemical comparative analysis of GFAP, MAP – 2, NOGO – a, OLIG – 2 and WT – 1 expression in WHO 2016 classified neuroepithelial tumours and their prognostic value. Pathol Res Pract. 2018;214(1):15–24. doi:10.1016/j.prp.2017.12.009
  • Kloosterhof NK, Bralten LBC, Dubbink HJ, French PJ, van den Bent MJ. Isocitrate dehydrogenase-1 mutations: a fundamentally new understanding of diffuse glioma? Lancet Oncol. 2011;12(1):83–91. doi:10.1016/S1470-2045(10)70053-X
  • Yusoff AAM, Zulfakhar FN, Sul’Ain MD, Idris Z, Abdullah JM. Association of the IDH1 C.395G>A (R132H) mutation with histological type in Malay brain tumors. Asian Pacific J Cancer Prevent. 2016;17(12):5195–5201. doi:10.22034/APJCP.2016.17.12.5195
  • Malueka RG, Dwianingsih EK, Bayuangga HF, et al. Clinicopathological features and prognosis of Indonesian patients with gliomas with IDH mutation: insights into its significance in a Southeast Asian population. Asian Pacific J Cancer Prevent. 2020;21(8):2287–2295. doi:10.31557/APJCP.2020.21.8.2287
  • Shen G, Wang R, Gao B, Zhang Z, Wu G, Pope W. The MRI features and prognosis of gliomas associated with idh1 mutation: a single center study in Southwest China. Front Oncol. 2020;10. doi:10.3389/fonc.2020.00852
  • Ichimura K. Molecular pathogenesis of IDH mutations in gliomas. Brain Tumor Pathol. 2012;29(3):131–139. doi:10.1007/s10014-012-0090-4
  • Wiestler B, Capper D, Holland-Letz T, et al. ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis. Acta Neuropathol. 2013;126(3):443–451. doi:10.1007/s00401-013-1156-z
  • Nandakumar P, Mansouri A, Das S. The role of ATRX in glioma biology. Front Oncol. 2017;7. doi:10.3389/fonc.2017.00236
  • Chen WJ, He DS, Tang RX, Ren FH, Chen G. Ki-67 is a valuable prognostic factor in gliomas: evidence from a systematic review and meta-analysis. Asian Pacific J Cancer Prevent. 2015;16(2):411–420. doi:10.7314/APJCP.2015.16.2.411

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.