226
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Associations Between Mean Platelet Volume and Risk of Deep Vein Thrombosis: A Mendelian Randomization Study and a Retrospective Study

&
Pages 515-524 | Received 11 Dec 2022, Accepted 18 Jan 2023, Published online: 08 Feb 2023

References

  • Danwang C, Bigna JJ, Awana AP, et al. Global epidemiology of venous thromboembolism in people with active tuberculosis: a systematic review and meta-analysis. J Thromb Thrombolysis. 2021;51(2):502–512. doi:10.1007/s11239-020-02211-7
  • Jain N, Avanthika C, Singh A, et al. Deep vein thrombosis in intravenous drug users: an invisible global health burden. Cureus. 2021;13(10). doi:10.7759/cureus.18457
  • Kearon C, de Wit K, Parpia S, et al. Diagnosis of deep vein thrombosis with D-dimer adjusted to clinical probability: prospective diagnostic management study. BMJ. 2022;376. doi:10.1016/j.thromres
  • Bellesini M, Robert‐Ebadi H, Combescure C, et al. D‐dimer to rule out venous thromboembolism during pregnancy: a systematic review and meta‐analysis. J Thromb Haemost. 2021;19(10):2454–2467. doi:10.1111/jth.15432
  • Bye AP, Unsworth AJ, Gibbins JM. Platelet signaling: a complex interplay between inhibitory and activatory networks. J Thromb Haemost. 2016;14(5):918–930. doi:10.1111/jth.13302
  • Barrett TJ, Lee AH, Xia Y, et al. Platelet and vascular biomarkers associate with thrombosis and death in coronavirus disease. Circ Res. 2020;127(7):945–947. doi:10.1161/CIRCRESAHA.120.317803
  • Çil H, Yavuz C, Islamoğlu Y, et al. Platelet count and mean platelet volume in patients with in-hospital deep venous thrombosis. Clin Appl Thromb Hemost. 2012;18(6):650–653. doi:10.1177/1076029611435838
  • Braekkan SK, Mathiesen EB, Njølstad I, et al. Mean platelet volume is a risk factor for venous thromboembolism: the Tromsø study. J Thromb Haemost. 2010;8(1):157–162. doi:10.1111/j.1538-7836.2009.03498.x
  • Wang Z, Chen X, Wu J, et al. Low mean platelet volume is associated with deep vein thrombosis in older patients with hip fracture. Clin Appl Thromb Hemost. 2022;28:10760296221078837. doi:10.1177/10760296221078837
  • Lippi G, Buonocore R, Cervellin G. The mean platelet volume is decreased in patients diagnosed with venous thromboembolism in the emergency department. Semin Thromb Hemost. 2016;42(06):632–635. doi:10.1055/s-0036-1571335
  • Burgess S, Swanson SA, Labrecque JA. Are Mendelian randomization investigations immune from bias due to reverse causation? Eur J Epidemiol. 2021;36(3):253–257. doi:10.1007/s10654-021-00726-8
  • Bowden J, Del Greco MF, Minelli C, et al. A framework for the investigation of pleiotropy in two‐sample summary data Mendelian randomization. Stat Med. 2017;36(11):1783–1802. doi:10.1002/sim.7221
  • Hemani G, Zheng J, Elsworth B, et al. The MR-Base platform supports systematic causal inference across the human phenome. Elife. 2018;7:e34408. doi:10.7554/eLife.34408
  • Gieger C, Radhakrishnan A, Cvejic A, et al. New gene functions in megakaryopoiesis and platelet formation. Nature. 2011;480(7376):201–208. doi:10.1038/nature10659
  • Schaid DJ, Chen W, Larson NB. From genome-wide associations to candidate causal variants by statistical fine-mapping. Nat Rev Genet. 2018;19(8):491–504. doi:10.1038/s41576-018-0016-z
  • Burgess S, Thompson SG. Bias in causal estimates from Mendelian randomization studies with weak instruments. Stat Med. 2011;30(11):1312–1323. doi:10.1002/sim.4197
  • Bowden J, Davey Smith G, Haycock PC, Burgess S. Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator. Genet epidemiol. 2016;40:304–314. doi:10.1002/gepi.21965
  • Yavorska OO, Burgess S. Mendelian Randomization: an R package for performing Mendelian randomization analyses using summarized data. Int J Epidemiol. 2017;46:1734–1739. doi:10.1093/ije/dyx034
  • Ferroni P, Guadagni F, Riondino S, et al. Evaluation of mean platelet volume as a predictive marker for cancer-associated venous thromboembolism during chemotherapy. Haematologica. 2014;99(10):1638. doi:10.3324/haematol.2014.109470
  • Riedl J, Kaider A, Reitter EM, et al. Association of mean platelet volume with risk of venous thromboembolism and mortality in patients with cancer. Thromb Haemost. 2014;111(04):670–678. doi:10.1160/TH13-07-0603
  • Icli A, Aksoy F, Turker Y, et al. Relationship between mean platelet volume and pulmonary embolism in patients with deep vein thrombosis. Heart Lung Circ. 2015;24(11):1081–1086. doi:10.1016/j.hlc.2015.04.170
  • Han JS, Park TS, Cho SY, et al. Increased mean platelet volume and mean platelet volume/platelet count ratio in Korean patients with deep vein thrombosis. Platelets. 2013;24(8):590–593. doi:10.3109/09537104.2012.748187
  • Yuan S, Li X, Morange PE, et al. Plasma phospholipid fatty acids and risk of venous thromboembolism: Mendelian randomization investigation. Nutrients. 2022;14(16):3354. doi:10.3390/nu14163354
  • Larsson SC, Bäck M, Rees JMB, et al. Body mass index and body composition in relation to 14 cardiovascular conditions in UK Biobank: a Mendelian randomization study. Eur Heart J. 2020;41(2):221–226. doi:10.1093/eurheartj/ehz388
  • He J, Jiang Q, Yao Y, et al. Blood cells and venous thromboembolism risk: a two-sample Mendelian randomization study. Front Cardiovasc Med. 2022;9. doi:10.3389/fcvm.2022.919640
  • Handtke S, Steil L, Palankar R, et al. Role of platelet size revisited function and protein composition of large and small platelets. Thromb Haemost. 2019;119(3):407‐20. doi:10.1055/s-0039-1677875