The Collateral Benefit of COVID Pandemic: Improved Pharmacological Venous Thromboembolism Prophylaxis Practices in Non-COVID Patients

References

• Heit JA, Silverstein MD, Mohr DN, et al. The epidemiology of venous thromboembolism in the community. Thromb Haemost. 2001;86(07):452–463. doi:10.1055/s-0037-1616243
   PubMedGoogle Scholar
• Goldsmith M, Whitelaw G, Cannaday DA. VTE as a quality indicator. J Natl Compr Canc Netw. 2008;6(8):754–759. doi:10.6004/jnccn.2008.0056
   PubMedGoogle Scholar
• The Joint Commission. National consensus standards for the prevention and care of Deep Vein Thrombosis (DVT); 2022. Available from: https://www.jointcommission.org/measurement/measures/venous-thromboembolism/. Accessed March 21, 2023.
   Google Scholar
• Anderson DR, Morgano GP, Bennett C, et al. American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized patients. Blood Adv. 2019;3(23):3898–3944. doi:10.1182/bloodadvances.2019000975
   PubMed Web of Science ®Google Scholar
• Geerts WH, Bergqvist D, Pineo GF, et al. Prevention of venous thromboembolism: American College of chest physicians evidence-based clinical practice guidelines (8th edition). Chest. 2008;133(6Suppl):381s–453s. doi:10.1378/chest.08-0656
   PubMedGoogle Scholar
• Bikdeli B, Sharif-Kashani B. Prophylaxis for venous thromboembolism: a great global divide between expert guidelines and clinical practice? Semin Thromb Hemost. 2012;38(2):144–155. doi:10.1055/s-0032-1301412
   PubMed Web of Science ®Google Scholar
• Michota FA. Bridging the gap between evidence and practice in venous thromboembolism prophylaxis: the quality improvement process. J Gen Intern Med. 2007;22(12):1762–1770. doi:10.1007/s11606-007-0369-z
   PubMed Web of Science ®Google Scholar
• Shedd GC, Franklin C, Schumacher AM, Green DE. Improving inpatient venous thromboembolism prophylaxis. South Med J. 2008;101(12):1209–1215. doi:10.1097/SMJ.0b013e31818da7e7
   PubMed Web of Science ®Google Scholar
• Spirk D, Stuck AK, Hager A, Engelberger RP, Aujesky D, Kucher N. Electronic alert system for improving appropriate thromboprophylaxis in hospitalized medical patients: a randomized controlled trial. J Thromb Haemost. 2017;15(11):2138–2146. doi:10.1111/jth.13812
   PubMed Web of Science ®Google Scholar
• Güven AT, Altintop SE, Özdede M, Uyaroğlu OA, Tanriöver MD. Quality gap in venous thromboembolism prophylaxis practices in inpatients: assessment of prophylaxis practices in a University Hospital. Int J Qual Health Care. 2021;33:3. doi:10.1093/intqhc/mzab104
   Web of Science ®Google Scholar
• Carbone M, Lednicky J, Xiao S-Y, Venditti M, Bucci E. Coronavirus 2019 infectious disease epidemic: where we are, what can be done and hope for. J Thorac Oncol. 2021;16(4):546–571. doi:10.1016/j.jtho.2020.12.014
   PubMed Web of Science ®Google Scholar
• Panigada M, Bottino N, Tagliabue P, et al. Hypercoagulability of COVID-19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis. J Thromb Haemost. 2020;18(7):1738–1742. doi:10.1111/jth.14850
   PubMed Web of Science ®Google Scholar
• Ranucci M, Ballotta A, Di Dedda U, et al. The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome. J Thromb Haemost. 2020;18(7):1747–1751. doi:10.1111/jth.14854
   PubMed Web of Science ®Google Scholar
• Kollias A, Kyriakoulis KG, Lagou S, Kontopantelis E, Stergiou GS, Syrigos K. Venous thromboembolism in COVID-19: a systematic review and meta-analysis. Vasc Med. 2021;26(4):415–425. doi:10.1177/1358863X21995566
   PubMed Web of Science ®Google Scholar
• Mansory EM, Srigunapalan S, Lazo-Langner A. Venous thromboembolism in hospitalized critical and noncritical COVID-19 patients: a systematic review and meta-analysis. TH Open. 2021;5(3):e286–e94. doi:10.1055/s-0041-1730967
   PubMedGoogle Scholar
• Wu C, Liu Y, Cai X, Zhang W, Li Y, Fu C. Prevalence of venous thromboembolism in critically ill patients with coronavirus disease 2019: a meta-analysis. Front Med. 2021;8:603558. doi:10.3389/fmed.2021.603558
   Web of Science ®Google Scholar
• Speretta GF, Leite RD. Covid-19: high rates of severity and death in elderly and patients with chronic diseases reinforces the importance of regular physical activity. Sport Sci Health. 2020;16(3):589–590. doi:10.1007/s11332-020-00678-8
   PubMedGoogle Scholar
• Sud A, Jones ME, Broggio J, et al. Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic. AnnOncol. 2020;31(8):1065–1074. doi:10.1016/j.annonc.2020.05.009
   Google Scholar
• Metzler B, Siostrzonek P, Binder RK, Bauer A, Reinstadler SJ. Decline of acute coronary syndrome admissions in Austria since the outbreak of COVID-19: the pandemic response causes cardiac collateral damage. Eur Heart J. 2020;41(19):1852–1853. doi:10.1093/eurheartj/ehaa314
   PubMed Web of Science ®Google Scholar
• Santi L, Golinelli D, Tampieri A, et al. Non-COVID-19 patients in times of pandemic: emergency department visits, hospitalizations and cause-specific mortality in Northern Italy. PLoS One. 2021;16(3):e0248995. doi:10.1371/journal.pone.0248995
   PubMed Web of Science ®Google Scholar
• Bilaloglu S, Aphinyanaphongs Y, Jones S, Iturrate E, Hochman J, Berger JS. Thrombosis in hospitalized patients with COVID-19 in a New York City Health System. JAMA. 2020;324(8):799–801. doi:10.1001/jama.2020.13372
   PubMed Web of Science ®Google Scholar
• Connors JM, Levy JH. Thromboinflammation and the hypercoagulability of COVID-19. J Thromb Haemost. 2020;18(7):1559–1561. doi:10.1111/jth.14849
   PubMed Web of Science ®Google Scholar
• von Meijenfeldt FA, Havervall S, Adelmeijer J, et al. Prothrombotic changes in patients with COVID-19 are associated with disease severity and mortality. Res Pract Thromb Haemost. 2021;5(1):132–141. doi:10.1002/rth2.12462
   PubMed Web of Science ®Google Scholar
• Hardy M, Michaux I, Lessire S, et al. Prothrombotic disturbances of hemostasis of patients with severe COVID-19: a prospective longitudinal observational study. Thromb Res. 2021;197:20–23. doi:10.1016/j.thromres.2020.10.025
   PubMed Web of Science ®Google Scholar
• von Meijenfeldt FA, Havervall S, Adelmeijer J, et al. Sustained prothrombotic changes in COVID-19 patients 4 months after hospital discharge. Blood Adv. 2021;5(3):756–759. doi:10.1182/bloodadvances.2020003968
   PubMed Web of Science ®Google Scholar
• Moores LK, Tritschler T, Brosnahan S, et al. Prevention, diagnosis, and treatment of VTE in patients with coronavirus disease 2019: CHEST guideline and expert panel report. Chest. 2020;158(3):1143–1163. doi:10.1016/j.chest.2020.05.559
   PubMed Web of Science ®Google Scholar
• Thachil J, Tang N, Gando S, et al. ISTH interim guidance on recognition and management of coagulopathy in COVID‐19. J Thromb Haemost. 2020;18(5):1023–1026. doi:10.1111/jth.14810
   PubMed Web of Science ®Google Scholar
• Flaczyk A, Rosovsky RP, Reed CT, Bankhead-Kendall BK, Bittner EA, Chang MG. Comparison of published guidelines for management of coagulopathy and thrombosis in critically ill patients with COVID 19: implications for clinical practice and future investigations. Crit Care. 2020;24(1):559. doi:10.1186/s13054-020-03273-y
   PubMed Web of Science ®Google Scholar
• Rosovsky RP, Sanfilippo KM, Wang TF, et al. Anticoagulation practice patterns in COVID‐19: a global survey. Res Pract Thromb Haemost. 2020;4(6):969–983. doi:10.1002/rth2.12414
   PubMed Web of Science ®Google Scholar
• Kyriakoulis KG, Dimakakos E, Kyriakoulis IG, et al. Practical recommendations for optimal thromboprophylaxis in patients with COVID-19: a consensus statement based on available clinical trials. J Clin Med. 2022;11(20):5997. doi:10.3390/jcm11205997
   PubMed Web of Science ®Google Scholar
• ATTACC, ACTIV-4a, and REMAP-CAP Investigators. Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19. N Engl J Med. 2021;385(9):790–802. doi:10.1056/NEJMoa2105911
   PubMed Web of Science ®Google Scholar
• Fröhlich GM, Jeschke E, Eichler U, et al. Impact of oral anticoagulation on clinical outcomes of COVID-19: a nationwide cohort study of hospitalized patients in Germany. Clin Res Cardiol. 2021;110:1041–1050.
   PubMed Web of Science ®Google Scholar
• Nadkarni GN, Lala A, Bagiella E, et al. Anticoagulation, bleeding, mortality, and pathology in hospitalized patients with COVID-19. J Am Coll Cardiol. 2020;76(16):1815–1826. doi:10.1016/j.jacc.2020.08.041
   PubMed Web of Science ®Google Scholar