Association of Triglyceride-Glucose Index with the Risk of Hyperhomocysteinemia Among Chinese Male Bus Drivers: A Longitudinal Study

References

• Chen PJ, Lu YC, Wang PM, Huang CF, Loke SS. Factors associated with hyperhomocysteinemia in relatively healthy Taiwanese adults: a retrospective medical record study. Medicine. 2021;100(3):e23829. doi:10.1097/MD.0000000000023829
   PubMed Web of Science ®Google Scholar
• Xiang Y, Zhao Q, Wang N, et al. Association of obesity with the risk of hyperhomocysteinemia among the Chinese community residents: a prospective cohort study in Shanghai, China. Nutrients. 2021;13(10):3648. doi:10.3390/nu13103648
   PubMed Web of Science ®Google Scholar
• Golinko V, Cheberyachko S, Deryugin O, Tretyak O, Dusmatova O. Assessment of the risks of occupational diseases of the passenger bus drivers. Saf Health Work. 2020;11:543–549. doi:10.1016/j.shaw.2020.07.005
   PubMed Web of Science ®Google Scholar
• Guieu R, Ruf J, Mottola G. Hyperhomocysteinemia and cardiovascular diseases. Ann Biol Clin. 2022;80(1):7–14. doi:10.1684/abc.2021.1694
   PubMed Web of Science ®Google Scholar
• Faeh D, Chiolero A, Paccaud F. Homocysteine as a risk factor for cardiovascular disease: should we (still) worry about? Swiss. Med Wkly. 2006;136:745–756.
   PubMed Web of Science ®Google Scholar
• Cacciapuoti F. Hyper-homocysteinemia: a novel risk factor or a powerful marker for cardiovascular diseases? Pathogenetic and therapeutical uncertainties. J Thromb Thrombolysis. 2011;32(1):82–88. doi:10.1007/s11239-011-0550-4
   PubMed Web of Science ®Google Scholar
• Tu W, Yan F, Chao B, Ji X, Wang L. Status of hyperhomocysteinemia in China: results from the China stroke high-risk population screening program, 2018. Front Med. 2021;15:903–912. doi:10.1007/s11684-021-0871-4
   PubMed Web of Science ®Google Scholar
• Kim J, Kim H, Roh H, Kwon Y. Causes of hyperhomocysteinemia and its pathological significance. Arch Pharm Res. 2018;41:372–383. doi:10.1007/s12272-018-1016-4
   PubMed Web of Science ®Google Scholar
• Van Dam F, Van Gool WA. Hyperhomocysteinemia and Alzheimer’s disease: a systematic review. Arch Gerontol Geriatr. 2009;48:425–430. doi:10.1016/j.archger.2008.03.009
   PubMed Web of Science ®Google Scholar
• Smith AD, Refsum H. Homocysteine, B vitamins, and cognitive impairment. Annu Rev Nutr. 2016;36:211–239. doi:10.1146/annurev-nutr-071715-050947
   PubMed Web of Science ®Google Scholar
• Ma N, Xu N, Yin D, Liu W, Wu M, Cheng X. Relationship between plasma total homocysteine and the severity of renal function in Chinese patients with type 2 diabetes mellitus aged ≥75 years. Medicine. 2020;99(27):e20737. doi:10.1097/MD.0000000000020737
   PubMed Web of Science ®Google Scholar
• Cohen E, Margalit I, Shochat T, Goldberg E, Krause I. Gender differences in homocysteine concentrations, a population-based cross-sectional study. Nutr Metab Cardiovasc Dis. 2019;29(1):9–14. doi:10.1016/j.numecd.2018.09.003
   PubMed Web of Science ®Google Scholar
• Wang W, Ji P, Wang Y, et al. Prevalence of hyperhomocysteinemia and its associated factors in patients with primary hypertension in Chinese urban communities: a cross-sectional study from Nanjing. Clin Exp Hypertens. 2018;40(5):495–500. doi:10.1080/10641963.2017.1403621
   PubMed Web of Science ®Google Scholar
• Osibogun O, Ogunmoroti O, Tibuakuu M, Benson EM, Michos ED. Sex differences in the association between ideal cardiovascular health and biomarkers of cardiovascular disease among adults in the United States: a cross-sectional analysis from the multiethnic study of atherosclerosis. BMJ Open. 2019;9(11):e031414. doi:10.1136/bmjopen-2019-031414
   PubMed Web of Science ®Google Scholar
• Yang Y, Zeng Y, Yuan S, et al. Prevalence and risk factors for hyperhomocysteinemia: a population-based cross-sectional study from Hunan, China. BMJ Open. 2021;11(12):e048575. doi:10.1136/bmjopen-2020-048575
   PubMed Web of Science ®Google Scholar
• Yang B, Fan S, Zhi X, et al. Prevalence of hyperhomocysteinemia in China: a systematic review and meta-analysis. Nutrients. 2015;7:74–90. doi:10.3390/nu7010074
   Web of Science ®Google Scholar
• Tao K, Li M, Ling J, Tu Y. Prevalence and correlative factors of hyperhomocysteinemia in elderly patients with femoral neck fracture: a cross-sectional study. J Clin Lab Anal. 2022;36(7):e24563. doi:10.1002/jcla.24563
   PubMed Web of Science ®Google Scholar
• Liu XD, Gao B, Sun D, et al. Prevalence of hyperhomocysteinaemia and some of its major determinants in Shaanxi Province, China: a cross-sectional study. Br J Nutr. 2015;113(4):691–698. doi:10.1017/S0007114514004218
   PubMed Web of Science ®Google Scholar
• Wu Y, Wu W, Lin Y, Xiong J, Zheng X. Blood pressure states transitions among bus drivers: the application of multi-state Markov model. Int Arch Occup Environ Health. 2022;95:1995–2003. doi:10.1007/s00420-022-01903-2
   PubMed Web of Science ®Google Scholar
• Park K, Ahn CW, Lee SB, et al. Elevated TyG Index Predicts Progression of Coronary Artery Calcification. Diabetes Care. 2019;42(8):1569–1573. doi:10.2337/dc18-1920
   PubMed Web of Science ®Google Scholar
• Ormazabal V, Nair S, Elfeky O, Aguayo C, Salomon C, Zuñiga FA. Association between insulin resistance and the development of cardiovascular disease. Cardiovasc Diabetol. 2018;17(1):122. doi:10.1186/s12933-018-0762-4
   PubMed Web of Science ®Google Scholar
• James DE, Stöckli J, Birnbaum MJ. The aetiology and molecular landscape of insulin resistance. Nat Rev Mol Cell Biol. 2021;22(11):751–771. doi:10.1038/s41580-021-00390-6
   PubMed Web of Science ®Google Scholar
• Guerrero-Romero F, Simental-Mendía LE, González-Ortiz M, et al. The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp. J Clin Endocrinol Metab. 2010;95(7):3347–3351. doi:10.1210/jc.2010-0288
   PubMed Web of Science ®Google Scholar
• Lv L, Zhou Y, Chen X, et al.; Chongqing Diabetes Registry Group. Relationship Between the TyG index and diabetic kidney disease in patients with type-2 diabetes mellitus. Diabetes Metab Syndr Obes. 2021;14:3299–3306. doi:10.2147/DMSO.S318255
   PubMed Web of Science ®Google Scholar
• Zhang R, Xu J, Li R, et al. Association between serum spermidine and TyG index: results from a cross-sectional study. Nutrients. 2022;14(18):3847. doi:10.3390/nu14183847
   PubMed Web of Science ®Google Scholar
• Bonora E, Targher G, Alberiche M, et al. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care. 2000;23(1):57–63. doi:10.2337/diacare.23.1.57
   PubMed Web of Science ®Google Scholar
• Yilmaz M, Karaaslan M, Tonyali S, Celik M, Toprak T, Odabas O. Triglyceride-Glucose Index (TyG) is associated with erectile dysfunction: a cross-sectional study. Andrology. 2021;9(1):238–244. doi:10.1111/andr.12904
   PubMed Web of Science ®Google Scholar
• Unger G, Benozzi SF, Perruzza F, Pennacchiotti GL. Triglycerides and glucose index: a useful indicator of insulin resistance. Endocrinol Nutr. 2014;61(10):533–540. doi:10.1016/j.endonu.2014.06.009
   PubMedGoogle Scholar
• Huang R, Wang Z, Chen J, et al. Prognostic value of triglyceride glucose (TyG) index in patients with acute decompensated heart failure. Cardiovasc Diabetol. 2022;21(1):88. doi:10.1186/s12933-022-01507-7
   PubMed Web of Science ®Google Scholar
• Guerrero-Romero F, Villalobos-Molina R, Jiménez-Flores JR, et al. Fasting triglycerides and glucose index as a diagnostic test for insulin resistance in young adults. Arch Med Res. 2016;47(5):382–387. doi:10.1016/j.arcmed.2016.08.012
   PubMed Web of Science ®Google Scholar
• Kang B, Yang Y, Lee EY, et al. Triglycerides/glucose index is a useful surrogate marker of insulin resistance among adolescents. Int J Obes. 2017;41(5):789–792. doi:10.1038/ijo.2017.14
   PubMed Web of Science ®Google Scholar
• Toro-Huamanchumo CJ, Urrunaga-Pastor D, Guarnizo-Poma M, et al.; Insulin Resistance and Metabolic Syndrome Research Group. Triglycerides and glucose index as an insulin resistance marker in a sample of healthy adults. Diabetes Metab Syndr. 2019;13(1):272–277. doi:10.1016/j.dsx.2018.09.010
   PubMed Web of Science ®Google Scholar
• Lee SB, Kim MK, Kang S, et al. Triglyceride glucose index is superior to the homeostasis model assessment of insulin resistance for predicting nonalcoholic fatty liver disease in Korean adults. Endocrinol Metab. 2019;34(2):179–186. doi:10.3803/EnM.2019.34.2
   Google Scholar
• Vasques AC, Novaes FS, de Oliveira Mda S, et al. TyG index performs better than HOMA in a Brazilian population: a hyperglycemic clamp validated study. Diabetes Res Clin Pract. 2011;93(3):e98–e100. doi:10.1016/j.diabres.2011.05.030
   PubMed Web of Science ®Google Scholar
• Simental-Mendía LE, Rodríguez-Morán M, Guerrero-Romero F. The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects. Metab Syndr Relat Disord. 2008;6(4):299–304. doi:10.1089/met.2008.0034
   PubMedGoogle Scholar
• Simões CF, Locatelli JC, de Oliveira GH, Lopes WA. It is time to standardize the TyG index. Endocrine. 2021;71(2):522–523. doi:10.1007/s12020-020-02448-5
   PubMed Web of Science ®Google Scholar
• World Health Organization. The WHO STEPwise approach to noncommunicable disease risk factor surveillance. World Heal Organ. 2017;36:1–474.
   Google Scholar
• Huang YF, Yang KH, Chen SH, et al. 高尿酸血症/痛风患者实践指南[Practice guideline for patients with hyperuricemia/gout]. Zhonghua Nei Ke Za Zhi. 2020;59(7):519–527. Chinese. doi:10.3760/cma.j.cn112138-20200505-00449
   PubMedGoogle Scholar
• Joint committee issued Chinese guideline for the management of dyslipidemia in adults. 中国成人血脂异常防治指南(2016年修订版)[2016 Chinese guideline for the management of dyslipidemia in adults]. Zhonghua Xin Xue Guan Bing Za Zhi. 2016;44(10):833–853. Chinese. doi:10.3760/cma.j.issn.0253-3758.2016.10.005
   PubMedGoogle Scholar
• Tao M, Pi X, Ma X, et al. Relationship between serum uric acid and clustering of cardiovascular disease risk factors and renal disorders among Shanghai population: a multicentre and cross-sectional study. BMJ Open. 2019;9:e025453. doi:10.1136/bmjopen-2018-025453
   PubMed Web of Science ®Google Scholar
• Yoo TK, Rhim HC, Lee YT, Yoon KJ, Park CH. Relationship between hyperhomocysteinemia and coexisting obesity with low skeletal muscle mass in asymptomatic adult population. Sci Rep. 2022;12(1):12439. doi:10.1038/s41598-022-16401-1
   PubMed Web of Science ®Google Scholar
• Choi JH, Seo JW, Lee MY, Lee YT, Yoon KJ, Park CH. Association between elevated plasma homocysteine and low skeletal muscle mass in asymptomatic adults. Endocrinol Metab. 2022;37(2):333–343. doi:10.3803/EnM.2021.1202
   Google Scholar
• Zheng L, Li B, Lin S, Chen L, Li H. Role and mechanism of cardiac insulin resistance in occurrence of heart failure caused by myocardial hypertrophy. Aging. 2019;11(16):6584–6590. doi:10.18632/aging.102212
   PubMedGoogle Scholar
• Zhou MS, Schulman IH, Zeng Q. Link between the renin-angiotensin system and insulin resistance: implications for cardiovascular disease. Vasc Med. 2012;17(5):330–341. doi:10.1177/1358863X12450094
   PubMed Web of Science ®Google Scholar
• Bloomgarden ZT. Inflammation and insulin resistance. Diabetes Care. 2003;26(6):1922–1926. doi:10.2337/diacare.26.6.1922
   PubMed Web of Science ®Google Scholar