KRT19 is a Promising Prognostic Biomarker and Associates with Immune Infiltrates in Serous Ovarian Cystadenocarcinoma

References

• Cheung A, Shah S, Parker J, et al. Non-epithelial ovarian cancers: how much do we really know? Int J Environ Res Public Health. 2022;19(3):1106. doi:10.3390/ijerph19031106
   PubMed Web of Science ®Google Scholar
• Lisio MA, Fu L, Goyeneche A, Gao ZH, Telleria C. High-grade serous ovarian cancer: basic sciences, clinical and therapeutic standpoints. Int J Mol Sci. 2019;20(4):952. doi:10.3390/ijms20040952
   PubMed Web of Science ®Google Scholar
• Heindl A, Khan AM, Rodrigues DN, et al. Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity. Nat Commun. 2018;9(1):3917. doi:10.1038/s41467-018-06130-3
   PubMedGoogle Scholar
• Shah S, Cheung A, Kutka M, Sheriff M, Boussios S. Epithelial ovarian cancer: providing evidence of predisposition genes. Int J Environ Res Public Health. 2022;19(13):8113. doi:10.3390/ijerph19138113
   PubMed Web of Science ®Google Scholar
• Gorski JW, Ueland FR, Kolesar JM. CCNE1 amplification as a predictive biomarker of chemotherapy resistance in epithelial ovarian cancer. Diagnostics. 2020;10(5):279. doi:10.3390/diagnostics10050279
   Web of Science ®Google Scholar
• Ghose A, Gullapalli SVN, Boussios S, et al. Applications of proteomics in ovarian cancer: dawn of a new era. Proteomes. 2022;10(2):16. doi:10.3390/proteomes10020016
   PubMed Web of Science ®Google Scholar
• Olalekan S, Xie B, Back R, Eckart H, Basu A. Characterizing the tumor microenvironment of metastatic ovarian cancer by single-cell transcriptomics. Cell Rep. 2021;35(8):109165. doi:10.1016/j.celrep.2021.109165
   PubMed Web of Science ®Google Scholar
• Fu X, Sun X, Li X, Sheng Z. Dedifferentiation of epidermal cells to stem cells in vivo. Lancet. 2001;358(9287):1067–1068. doi:10.1016/S0140-6736(01)06202-X
   PubMed Web of Science ®Google Scholar
• Yuan X, Yi M, Dong B, Chu Q, Wu K. Prognostic significance of KRT19 in lung squamous cancer. J Cancer. 2021;12(4):1240–1248. doi:10.7150/jca.51179
   PubMed Web of Science ®Google Scholar
• Mi L, Liang N, Sun H. A comprehensive analysis of KRT19 combined with immune infiltration to predict breast cancer prognosis. Genes. 2022;13(10):1838. doi:10.3390/genes13101838
   PubMed Web of Science ®Google Scholar
• Wang X, Xu X, Peng C, et al. BRAF (V600E)-induced KRT19 expression in thyroid cancer promotes lymph node metastasis via EMT. Oncol Lett. 2019;18(1):927–935. doi:10.3892/ol.2019.10360
   PubMed Web of Science ®Google Scholar
• Quail DF, Joyce JA. Microenvironmental regulation of tumor progression and metastasis. Nat Med. 2013;19(11):1423–1437. doi:10.1038/nm.3394
   PubMed Web of Science ®Google Scholar
• Kalafati L, Kourtzelis I, Schulte-Schrepping J, et al. Innate immune training of granulopoiesis promotes anti-tumor activity. Cell. 2020;183(3):771–785.e712. doi:10.1016/j.cell.2020.09.058
   PubMed Web of Science ®Google Scholar
• Revythis A, Limbu A, Mikropoulos C, et al. Recent insights into PARP and immuno-checkpoint inhibitors in epithelial ovarian cancer. Int J Environ Res Public Health. 2022;19(14):8577. doi:10.3390/ijerph19148577
   PubMed Web of Science ®Google Scholar
• Baci D, Bosi A, Gallazzi M, et al. The ovarian cancer tumor immune microenvironment (TIME) as target for therapy: a focus on innate immunity cells as therapeutic effectors. Int J Mol Sci. 2020;21(9):3125. doi:10.3390/ijms21093125
   PubMed Web of Science ®Google Scholar
• Blum A, Wang P, Zenklusen JC. SnapShot: TCGA-analyzed tumors. Cell. 2018;173(2):530. doi:10.1016/j.cell.2018.03.059
   PubMed Web of Science ®Google Scholar
• Consortium G, Thomas J, Salvatore M. The Genotype-Tissue Expression (GTEx) project. Nat Genet. 2013;45(6):580–585. doi:10.1038/ng.2653
   PubMed Web of Science ®Google Scholar
• Chandrashekar DS, Bashel B, Balasubramanya SAH, et al. UALCAN: a portal for facilitating tumor subgroup gene expression and survival analyses. Neoplasia. 2017;19(8):649–658. doi:10.1016/j.neo.2017.05.002
   PubMed Web of Science ®Google Scholar
• Chen F, Chandrashekar DS, Varambally S, Creighton CJ. Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers. Nat Commun. 2019;10(1):5679. doi:10.1038/s41467-019-13528-0
   PubMed Web of Science ®Google Scholar
• Uhlén M, Fagerberg L, Hallström BM, et al. Proteomics. Tissue-based map of the human proteome. Science. 2015;347(6220):1260419. doi:10.1126/science.1260419
   PubMed Web of Science ®Google Scholar
• Yuan H, Yan M, Zhang G, et al. CancerSEA: a cancer single-cell state atlas. Nucleic Acids Res. 2019;47(D1):D900–d908. doi:10.1093/nar/gky939
   PubMed Web of Science ®Google Scholar
• Ru B, Wong CN, Tong Y, et al. TISIDB: an integrated repository portal for tumor-immune system interactions. Bioinformatics. 2019;35(20):4200–4202. doi:10.1093/bioinformatics/btz210
   PubMed Web of Science ®Google Scholar
• Bowen NJ, Walker LD, Matyunina LV, et al. Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells. BMC Med Genomics. 2009;2:71. doi:10.1186/1755-8794-2-71
   PubMed Web of Science ®Google Scholar
• Zhao X, Liu J, Ge S, et al. Saikosaponin A inhibits breast cancer by regulating Th1/Th2 balance. Front Pharmacol. 2019;10:624. doi:10.3389/fphar.2019.00624
   PubMed Web of Science ®Google Scholar
• Nagarsheth N, Wicha MS, Zou W. Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy. Nat Rev Immunol. 2017;17(9):559–572. doi:10.1038/nri.2017.49
   PubMed Web of Science ®Google Scholar
• Bell DA, Scully RE. Early de novo ovarian carcinoma. A study of fourteen cases. Cancer. 1994;73(7):1859–1864. doi:10.1002/1097-0142(19940401)73:7<1859::AID-CNCR2820730714>3.0.CO;2-L
   PubMed Web of Science ®Google Scholar
• Alsharif S, Sharma P, Bursch K, et al. Keratin 19 maintains E-cadherin localization at the cell surface and stabilizes cell-cell adhesion of MCF7 cells. Cell Adh Migr. 2021;15(1):1–17. doi:10.1080/19336918.2020.1868694
   PubMed Web of Science ®Google Scholar
• Gao A, Zhang L, Chen X, et al. Effect of VTCN1 on progression and metastasis of ovarian carcinoma in vitro and vivo. Biomed Pharmacother. 2015;73:129–134. doi:10.1016/j.biopha.2015.05.016
   PubMed Web of Science ®Google Scholar
• Huang X, Zhang X, Li E, et al. Vista: an immune regulatory protein checking tumor and immune cells in cancer immunotherapy. J Hematol Oncol. 2020;13(1):83. doi:10.1186/s13045-020-00917-y
   PubMed Web of Science ®Google Scholar
• Mulati K, Hamanishi J, Matsumura N, et al. Vista expressed in tumour cells regulates T cell function. Br J Cancer. 2019;120(1):115–127. doi:10.1038/s41416-018-0313-5
   PubMed Web of Science ®Google Scholar
• Philips GK, Atkins M. Therapeutic uses of anti-PD-1 and anti-PD-L1 antibodies. Int Immunol. 2015;27(1):39–46. doi:10.1093/intimm/dxu095
   PubMed Web of Science ®Google Scholar
• Vilgelm AE, Richmond A. Chemokines modulate immune surveillance in tumorigenesis, metastasis, and response to immunotherapy. Front Immunol. 2019;10:333. doi:10.3389/fimmu.2019.00333
   PubMed Web of Science ®Google Scholar
• Xiao S, Xie W, Zhou L. Mucosal chemokine CXCL17: what is known and not known. Scand J Immunol. 2021;93(2):e12965. doi:10.1111/sji.12965
   PubMed Web of Science ®Google Scholar
• Oka T, Sugaya M, Takahashi N, et al. CXCL17 attenuates imiquimod-induced psoriasis-like skin inflammation by recruiting myeloid-derived suppressor cells and regulatory T cells. J Immunol. 2017;198(10):3897–3908. doi:10.4049/jimmunol.1601607
   PubMed Web of Science ®Google Scholar
• Tucureanu MM, Butoi E, Gan AM, et al. Amendment of the cytokine profile in macrophages subsequent to their interaction with smooth muscle cells: differential modulation by fractalkine and resistin. Cytokine. 2016;83:250–261. doi:10.1016/j.cyto.2016.04.019
   PubMed Web of Science ®Google Scholar
• Helmke A, Nordlohne J, Balzer MS, et al. CX3CL1-CX3CR1 interaction mediates macrophage-mesothelial cross talk and promotes peritoneal fibrosis. Kidney Int. 2019;95(6):1405–1417. doi:10.1016/j.kint.2018.12.030
   PubMed Web of Science ®Google Scholar