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Clinical Neurology

Serum Sestrin2 Emerges as a Prognostic Biomarker of Human Aneurysmal Subarachnoid Hemorrhage: A Prospective Observational Cohort Single-Center Study

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Pages 3869-3887 | Received 28 Jun 2023, Accepted 23 Aug 2023, Published online: 28 Aug 2023

References

  • Connolly ES Jr, Rabinstein AA, Carhuapoma JR, et al. Guidelines for the management of aneurysmal subarachnoid hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2012;43(6):1711–1737. doi:10.1161/STR.0b013e3182587839
  • Lauzier DC, Jayaraman K, Yuan JY, et al. Early brain injury after subarachnoid hemorrhage: incidence and mechanisms. Stroke. 2023;54(5):1426–1440. doi:10.1161/STROKEAHA.122.040072
  • Ikram A, Javaid MA, Ortega-Gutierrez S, et al. Delayed cerebral ischemia after subarachnoid hemorrhage. J Stroke Cerebrovasc Dis. 2021;30(11):106064. doi:10.1016/j.jstrokecerebrovasdis.2021.106064
  • Osgood ML. Aneurysmal subarachnoid hemorrhage: review of the pathophysiology and management strategies. Curr Neurol Neurosci Rep. 2021;21(9):50. doi:10.1007/s11910-021-01136-9
  • Lucke-Wold BP, Logsdon AF, Manoranjan B, et al. Aneurysmal subarachnoid hemorrhage and neuroinflammation: a comprehensive review. Int J Mol Sci. 2016;17(4):497. doi:10.3390/ijms17040497
  • Yang Y, Chen S, Zhang JM. The updated role of oxidative stress in subarachnoid hemorrhage. Curr Drug Deliv. 2017;14(6):832–842. doi:10.2174/1567201813666161025115531
  • Wu F, Liu Z, Li G, et al. Inflammation and oxidative stress: potential targets for improving prognosis after subarachnoid hemorrhage. Front Cell Neurosci. 2021;15:739506. doi:10.3389/fncel.2021.739506
  • Fang Y, Lu J, Zheng J, et al. Comparison of aneurysmal subarachnoid hemorrhage grading scores in patients with aneurysm clipping and coiling. Sci Rep. 2020;10(1):9199. doi:10.1038/s41598-020-66160-0
  • Zheng YK, Dong XQ, Du Q, et al. Comparison of plasma copeptin and multiple biomarkers for assessing prognosis of patients with aneurysmal subarachnoid hemorrhage. Clin Chim Acta. 2017;475:64–69. doi:10.1016/j.cca.2017.10.009
  • Rodríguez-Rodríguez A, Egea-Guerrero JJ, Ruiz de Azúa-López Z, Murillo-Cabezas F. Biomarkers of vasospasm development and outcome in aneurysmal subarachnoid hemorrhage. J Neurol Sci. 2014;341(1–2):119–127. doi:10.1016/j.jns.2014.04.020
  • Che X, Chai J, Fang Y, et al. Sestrin2 in hypoxia and hypoxia-related diseases. Redox Rep. 2021;26(1):111–116. doi:10.1080/13510002.2021.1948774
  • Pasha M, Eid AH, Eid AA, Gorin Y, Munusamy S. Sestrin2 as a novel biomarker and therapeutic target for various diseases. Oxid Med Cell Longev. 2017;2017:3296294. doi:10.1155/2017/3296294
  • Zhang DW, Wei YY, Ji S, Fei GH. Correlation between sestrin2 expression and airway remodeling in COPD. BMC Pulm Med. 2020;20(1):297. doi:10.1186/s12890-020-01329-x
  • Kishimoto Y, Aoyama M, Saita E, et al. Association between plasma sestrin2 levels and the presence and severity of coronary artery disease. Dis Markers. 2020;2020:7439574. doi:10.1155/2020/7439574
  • Chung HS, Hwang HJ, Hwang SY, et al. Association of serum Sestrin2 level with metabolic risk factors in newly diagnosed drug-naïve type 2 diabetes. Diabetes Res Clin Pract. 2018;144:34–41. doi:10.1016/j.diabres.2018.07.024
  • Kishimoto Y, Kondo K, Momiyama Y. The protective role of sestrin2 in atherosclerotic and cardiac diseases. Int J Mol Sci. 2021;22(3):1200. doi:10.3390/ijms22031200
  • Shi X, Doycheva DM, Xu L, Tang J, Yan M, Zhang JH. Sestrin2 induced by hypoxia inducible factor 1 alpha protects the blood-brain barrier via inhibiting VEGF after severe hypoxic-ischemic injury in neonatal rats. Neurobiol Dis. 2016;95:111–121. doi:10.1016/j.nbd.2016.07.016
  • Liu X, Li M, Zhu J, Huang W, Song J. Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling. Hum Exp Toxicol. 2021;40(7):1095–1111. doi:10.1177/0960327120984224
  • Yang Y, Ding H, Yang C, et al. Sestrin2 provides cerebral protection through activation of Nrf2 signaling in microglia following subarachnoid hemorrhage. Front Immunol. 2023;14:1089576. doi:10.3389/fimmu.2023.1089576
  • Rai N, Upadhyay AD, Goyal V, Dwivedi S, Dey AB, Dey S. Sestrin2 as serum protein marker and potential therapeutic target for Parkinson’s disease. J Gerontol a Biol Sci Med Sci. 2020;75(4):690–695. doi:10.1093/gerona/glz234
  • Rai N, Kumar R, Desai GR, et al. Relative alterations in blood-based levels of sestrin in Alzheimer’s disease and mild cognitive impairment patients. J Alzheimers Dis. 2016;54(3):1147–1155. doi:10.3233/JAD-160479
  • Vergouwen MD, Vermeulen M, van Gijn J, et al. Definition of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies: proposal of a multidisciplinary research group. Stroke. 2010;41(10):2391–2395. doi:10.1161/STROKEAHA.110.589275
  • Jiang F, Chen Z, Hu J, Liu Q. Serum soluble scavenger receptor A levels are associated with delayed cerebral ischemia and poor clinical outcome after aneurysmal subarachnoid hemorrhage: a prospective observational study. Neuropsychiatr Dis Treat. 2022;18:2529–2541. doi:10.2147/NDT.S387487
  • Wang P, Zhao Y, Li Y, et al. Sestrin2 overexpression attenuates focal cerebral ischemic injury in rat by increasing Nrf2/HO-1 pathway-mediated angiogenesis. Neuroscience. 2019;410:140–149. doi:10.1016/j.neuroscience.2019.05.005
  • Chuang YC, Yang JL, Yang DI, Lin TK, Liou CW, Chen SD. Roles of sestrin2 and ribosomal protein S6 in transient global ischemia-induced hippocampal neuronal injury. Int J Mol Sci. 2015;16(11):26406–26416. doi:10.3390/ijms161125963
  • Zhang LL, Zhang ZJ. Sestrin2 aggravates oxidative stress of neurons by decreasing the expression of Nrf2. Eur Rev Med Pharmacol Sci. 2018;22(11):3493–3501. doi:10.26355/eurrev_201806_15176