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General Medicine

Association of Apolipoprotein E Gene Polymorphism with Type 2 Diabetic Nephropathy in the Southern Chinese Population

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Pages 5549-5558 | Received 13 Sep 2023, Accepted 12 Nov 2023, Published online: 23 Nov 2023

References

  • Satirapoj B. Nephropathy in diabetes. Adv Exp Med Biol. 2012;771:107–122. doi:10.1007/978-1-4614-5441-0_11
  • Jadawji C, Crasto W, Gillies C, et al. Prevalence and progression of diabetic nephropathy in South Asian, white European and African Caribbean people with type 2 diabetes: a systematic review and meta-analysis. Diabetes Obes Metab. 2019;21(3):658–673. doi:10.1111/dom.13569
  • Demir Y, Ceylan H, Turkes C, Beydemir S. Molecular docking and inhibition studies of vulpinic, carnosic and usnic acids on polyol pathway enzymes. J Biomol Struct Dyn. 2022;40(22):12008–12021. doi:10.1080/07391102.2021.1967195
  • Sever B, Altintop MD, Demir Y, Akalin Ciftci G, Beydemir S, Ozdemir A. Design, synthesis, in vitro and in silico investigation of aldose reductase inhibitory effects of new thiazole-based compounds. Bioorg Chem. 2020;102:104110. doi:10.1016/j.bioorg.2020.104110
  • Gross JL, de Azevedo MJ, Silveiro SP, Canani LH, Caramori ML, Zelmanovitz T. Diabetic nephropathy: diagnosis, prevention, and treatment. Diabetes Care. 2005;28(1):164–176. doi:10.2337/diacare.28.1.164
  • McCullough KP, Morgenstern H, Saran R, Herman WH, Robinson BM. Projecting ESRD incidence and prevalence in the United States through 2030. J Am Soc Nephrol. 2019;30(1):127–135. doi:10.1681/ASN.2018050531
  • Tuttle KR, Bakris GL, Bilous RW, et al. Diabetic kidney disease: a report from an ADA Consensus Conference. Diabetes Care. 2014;37(10):2864–2883. doi:10.2337/dc14-1296
  • Li Y, Ning Y, Shen B, et al. Temporal trends in prevalence and mortality for chronic kidney disease in China from 1990 to 2019: an analysis of the Global Burden of Disease Study 2019. Clin Kidney J. 2023;16(2):312–321. doi:10.1093/ckj/sfac218
  • Molitch ME, DeFronzo RA, Franz MJ, et al. Nephropathy in diabetes. Diabetes Care. 2004;27(Suppl 1):S79–83. doi:10.2337/diacare.27.2007.s79
  • Sever B, Altıntop MD, Demir Y, et al. An extensive research on aldose reductase inhibitory effects of new 4H-1,2,4-triazole derivatives. J Mol Struct. 2021;1224:129446. doi:10.1016/j.molstruc.2020.129446
  • Sever B, Altintop MD, Demir Y, et al. Identification of a new class of potent aldose reductase inhibitors: design, microwave-assisted synthesis, in vitro and in silico evaluation of 2-pyrazolines. Chem Biol Interact. 2021;345:109576. doi:10.1016/j.cbi.2021.109576
  • Ayodele OE, Alebiosu CO, Salako BL. Diabetic nephropathy--a review of the natural history, burden, risk factors and treatment. J Natl Med Assoc. 2004;96(11):1445–1454.
  • Akdağ M, Özçelik AB, Demir Y, Beydemir Ş. Design, synthesis, and aldose reductase inhibitory effect of some novel carboxylic acid derivatives bearing 2-substituted-6-aryloxo-pyridazinone moiety. J Mol Struct. 2022;1258:132675. doi:10.1016/j.molstruc.2022.132675
  • Turkes C, Arslan M, Demir Y, Cocaj L, Nixha AR, Beydemir S. N-substituted phthalazine sulfonamide derivatives as non-classical aldose reductase inhibitors. J Mol Recognit. 2022;35(12):e2991. doi:10.1002/jmr.2991
  • Cheung CY, Ma MKM, Chak WL, Tang SCW. Cancer risk in patients with diabetic nephropathy: a retrospective cohort study in Hong Kong. Medicine. 2017;96(38):e8077. doi:10.1097/MD.0000000000008077
  • Mise K, Galvan DL, Danesh FR. Shaping up mitochondria in diabetic nephropathy. Kidney360. 2020;1(9):982–992. doi:10.34067/kid.0002352020
  • Seyed Ahmadi S, Svensson AM, Pivodic A, Rosengren A, Lind M. Risk of atrial fibrillation in persons with type 2 diabetes and the excess risk in relation to glycaemic control and renal function: a Swedish cohort study. Cardiovasc Diabetol. 2020;19(1):9. doi:10.1186/s12933-019-0983-1
  • Alim Z, Kilic D, Demir Y. Some indazoles reduced the activity of human serum paraoxonase 1, an antioxidant enzyme: in vitro inhibition and molecular modeling studies. Arch Physiol Biochem. 2019;125(5):387–395. doi:10.1080/13813455.2018.1470646
  • Caliskan B, Demir Y, Turkes C. Ophthalmic drugs: in vitro paraoxonase 1 inhibition and molecular docking studies. Biotechnol Appl Biochem. 2022;69(6):2273–2283. doi:10.1002/bab.2284
  • Wu L, Parhofer KG. Diabetic dyslipidemia. Metabolism. 2014;63(12):1469–1479. doi:10.1016/j.metabol.2014.08.010
  • Ng MC, Baum L, So WY, et al. Association of lipoprotein lipase S447X, apolipoprotein E exon 4, and apoC3 −455T>C polymorphisms on the susceptibility to diabetic nephropathy. Clin Genet. 2006;70(1):20–28. doi:10.1111/j.1399-0004.2006.00628.x
  • Shah VN, Cheema BS, Sharma R, et al. ACACbeta gene (rs2268388) and AGTR1 gene (rs5186) polymorphism and the risk of nephropathy in Asian Indian patients with type 2 diabetes. Mol Cell Biochem. 2013;372(1–2):191–198. doi:10.1007/s11010-012-1460-2
  • Wu LS, Hsieh CH, Pei D, Hung YJ, Kuo SW, Lin E. Association and interaction analyses of genetic variants in ADIPOQ, ENPP1, GHSR, PPARgamma and TCF7L2 genes for diabetic nephropathy in a Taiwanese population with type 2 diabetes. Nephrol Dial Transplant. 2009;24(11):3360–3366. doi:10.1093/ndt/gfp271
  • Herman-Edelstein M, Scherzer P, Tobar A, Levi M, Gafter U. Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy. J Lipid Res. 2014;55(3):561–572. doi:10.1194/jlr.P040501
  • Demir Y, Tokali FS, Kalay E, et al. Synthesis and characterization of novel acyl hydrazones derived from vanillin as potential aldose reductase inhibitors. Mol Divers. 2023;27(4):1713–1733. doi:10.1007/s11030-022-10526-1
  • Tokali FS, Demir Y, Turkes C, Dincer B, Beydemir S. Novel acetic acid derivatives containing quinazolin-4(3H)-one ring: synthesis, in vitro, and in silico evaluation of potent aldose reductase inhibitors. Drug Dev Res. 2023;84(2):275–295. doi:10.1002/ddr.22031
  • Beydemir S, Demir Y. Antiepileptic drugs: impacts on human serum paraoxonase-1. J Biochem Mol Toxicol. 2017;31(6). doi:10.1002/jbt.21889
  • DemİR Y, BeydemİR Ş. Purification, refolding, and characterization of recombinant human paraoxonase-1. Turk J Chem. 2015;39:764–776. doi:10.3906/kim-1501-51
  • Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science. 1988;240(4852):622–630. doi:10.1126/science.3283935
  • Mahley RW, Rall SC Jr. Apolipoprotein E: far more than a lipid transport protein. Annu Rev Genomics Hum Genet. 2000;1:507–537. doi:10.1146/annurev.genom.1.1.507
  • Marais AD. Apolipoprotein E in lipoprotein metabolism, health and cardiovascular disease. Pathology. 2019;51(2):165–176. doi:10.1016/j.pathol.2018.11.002
  • Saadat M. Apolipoprotein E (APOE) polymorphisms and susceptibility to breast cancer: a Meta-Analysis. Cancer Res Treat. 2012;44(2):121–126. doi:10.4143/crt.2012.44.2.121
  • Horejsi B, Ceska R. Apolipoproteins and atherosclerosis. Apolipoprotein E and apolipoprotein(a) as candidate genes of premature development of atherosclerosis. Physiol Res. 2000;49(Suppl 1):S63–9.
  • Achouri-Rassas A, Ali NB, Cherif A, et al. Association between ACE polymorphism, cognitive phenotype and APOE E4 allele in a Tunisian population with Alzheimer disease. J Neural Transm. 2016;123(3):317–321. doi:10.1007/s00702-015-1468-3
  • Al-Dabbagh NM, Al-Dohayan N, Arfin M, Tariq M. Apolipoprotein E polymorphisms and primary glaucoma in Saudis. Mol Vis. 2009;15:912–919.
  • Jairani PS, Aswathy PM, Gopala S, Verghese J, Mathuranath PS. Interaction with the MAPT H1H1 genotype increases dementia risk in APOE epsilon4 carriers in a population of southern India. Dement Geriatr Cogn Disord. 2016;42(5–6):255–264. doi:10.1159/000447446
  • Zhong Z, Wu H, Wu H, Zhao P. Analysis of apolipoprotein E genetic polymorphism in a large ethnic Hakka population in southern China. Genet Mol Biol. 2018;41(4):742–749. doi:10.1590/1678-4685-GMB-2017-0301
  • Jiang Y, Ma L, Han C, et al. Effects of Apolipoprotein E isoforms in diabetic nephropathy of Chinese Type 2 Diabetic Patients. J Diabetes Res. 2017;2017:3560920. doi:10.1155/2017/3560920
  • Araki S, Koya D, Makiishi T, et al. APOE polymorphism and the progression of diabetic nephropathy in Japanese subjects with type 2 diabetes: results of a prospective observational follow-up study. Diabetes Care. 2003;26(8):2416–2420. doi:10.2337/diacare.26.8.2416
  • Resnick HE, Foster GL, Bardsley J, Ratner RE. Achievement of American Diabetes Association clinical practice recommendations among U.S. adults with diabetes, 1999–2002: the National Health and Nutrition Examination Survey. Diabetes Care. 2006;29(3):531–537. doi:10.2337/diacare.29.03.06.dc05-1254
  • Hsieh MC, Lin SR, Yang YC, Chen HC, Lin JN, Shin SJ. Higher frequency of apolipoprotein E2 allele in type 2 diabetic patients with nephropathy in Taiwan. J Nephrol. 2002;15(4):368–373.
  • Marrero JA, Kulik LM, Sirlin CB, et al. Diagnosis, staging, and management of hepatocellular carcinoma: 2018 practice guidance by the American Association for the study of liver diseases. Hepatology. 2018;68(2):723–750. doi:10.1002/hep.29913
  • Remuzzi G, Schieppati A, Ruggenenti P. Clinical practice. Nephropathy in patients with type 2 diabetes. N Engl J Med. 2002;346(15):1145–1151. doi:10.1056/NEJMcp011773
  • American Diabetes A. Standards of medical care in diabetes--2013. Diabetes Care. 2013;36(Suppl 1):S11–66. doi:10.2337/dc13-S011
  • Turkes C, Demir Y, Beydemir S. Anti-diabetic properties of calcium channel blockers: inhibition effects on aldose reductase enzyme activity. Appl Biochem Biotechnol. 2019;189(1):318–329. doi:10.1007/s12010-019-03009-x
  • Xu M, Wu P, Shen F, Ji J, Rakesh KP. Chalcone derivatives and their antibacterial activities: current development. Bioorg Chem. 2019;91:103133. doi:10.1016/j.bioorg.2019.103133
  • Gan C, Zhang Y, Liang F, Guo X, Zhong Z. Effects of APOE gene epsilon4 allele on serum lipid profiles and risk of cardiovascular disease and tumorigenesis in southern Chinese population. World J Surg Oncol. 2022;20(1):280. doi:10.1186/s12957-022-02748-2
  • Hou J, Deng Q, Guo X, Deng X, Zhong W, Zhong Z. Association between apolipoprotein E gene polymorphism and the risk of coronary artery disease in Hakka postmenopausal women in southern China. Lipids Health Dis. 2020;19(1):139. doi:10.1186/s12944-020-01323-6
  • Altintop MD, Demir Y, Turkes C, et al. A new series of hydrazones as small-molecule aldose reductase inhibitors. Arch Pharm. 2023;356(4):e2200570. doi:10.1002/ardp.202200570
  • Ertano BY, Demir Y, Nural Y, Erdoğan O. Investigation of the effect of acylthiourea derivatives on diabetes-associated enzymes. ChemistrySelect. 2022;7(46):e202204149. doi:10.1002/slct.202204149
  • Khalil YA, Rabes JP, Boileau C, Varret M. APOE gene variants in primary dyslipidemia. Atherosclerosis. 2021;328:11–22. doi:10.1016/j.atherosclerosis.2021.05.007
  • Yin YW, Qiao L, Sun QQ, et al. Influence of apolipoprotein E gene polymorphism on development of type 2 diabetes mellitus in Chinese Han population: a meta-analysis of 29 studies. Metabolism. 2014;63(4):532–541. doi:10.1016/j.metabol.2013.12.008
  • Reis KA, Ebinc FA, Koc E, et al. Association of the angiotensinogen M235T and APO E gene polymorphisms in Turkish type 2 diabetic patients with and without nephropathy. Ren Fail. 2011;33(5):469–474. doi:10.3109/0886022X.2011.568133
  • Atta MI, Abo Gabal K, El-Hadidi K, Swellam M, Genina A, Zaher NF. Apolipoprotein E genotyping in Egyptian diabetic nephropathy patients. IUBMB Life. 2016;68(1):58–64. doi:10.1002/iub.1460
  • Rall SC Jr, Weisgraber KH, Mahley RW. Human apolipoprotein E. The complete amino acid sequence. J Biol Chem. 1982;257(8):4171–4178. doi:10.1016/S0021-9258(18)34702-1
  • Blue ML, Williams DL, Zucker S, Khan SA, Blum CB. Apolipoprotein E synthesis in human kidney, adrenal gland, and liver. Proc Natl Acad Sci U S A. 1983;80(1):283–287. doi:10.1073/pnas.80.1.283
  • Seripa D, D’Onofrio G, Panza F, Cascavilla L, Masullo C, Pilotto A. The genetics of the human APOE polymorphism. Rejuvenation Res. 2011;14(5):491–500. doi:10.1089/rej.2011.1169
  • Rao H, Wu H, Yu Z, Huang Q. APOE genetic polymorphism rs7412 T/T genotype may be a risk factor for essential hypertension among Hakka people in Southern China. Int J Hypertens. 2022;2022:8145896. doi:10.1155/2022/8145896
  • Karahan Z, Ugurlu M, Ucaman B, et al. Relation between apolipoprotein E gene polymorphism and severity of coronary artery disease in acute myocardial infarction. Cardiol Res Pract. 2015;2015:363458. doi:10.1155/2015/363458
  • Demirag MD, Onen HI, Karaoguz MY, et al. Apolipoprotein E gene polymorphism in nonalcoholic fatty liver disease. Dig Dis Sci. 2007;52(12):3399–3403. doi:10.1007/s10620-007-9740-5
  • Chaudhary R, Likidlilid A, Peerapatdit T, et al. Apolipoprotein E gene polymorphism: effects on plasma lipids and risk of type 2 diabetes and coronary artery disease. Cardiovasc Diabetol. 2012;11:36. doi:10.1186/1475-2840-11-36
  • Broce IJ, Tan CH, Fan CC, et al. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease. Acta Neuropathol. 2019;137(2):209–226. doi:10.1007/s00401-018-1928-6
  • Eto M, Saito M, Okada M, et al. Apolipoprotein E genetic polymorphism, remnant lipoproteins, and nephropathy in type 2 diabetic patients. Am J Kidney Dis. 2002;40(2):243–251. doi:10.1053/ajkd.2002.34502
  • Ilhan N, Kahraman N, Seckin D, Ilhan N, Colak R. Apo E gene polymorphism on development of diabetic nephropathy. Cell Biochem Funct. 2007;25(5):527–532. doi:10.1002/cbf.1348
  • Karimoei M, Pasalar P, Mehrabzadeh M, et al. Association between apolipoprotein E polymorphism and nephropathy in Iranian diabetic patients. Saudi J Kidney Dis Transpl. 2017;28(5):997–1002. doi:10.4103/1319-2442.215137
  • Erdogan M, Eroglu Z, Biray C, et al. The relationship of the apolipoprotein E gene polymorphism Turkish Type 2 diabetic patients with and without nephropathy. J Endocrinol Invest. 2009;32(3):219–222. doi:10.1007/BF03346455
  • Bonnet F, Cooper ME. Potential influence of lipids in diabetic nephropathy: insights from experimental data and clinical studies. Diabetes Metab. 2000;26(4):254–264.
  • Kasiske BL, O’Donnell MP, Schmitz PG, Kim Y, Keane WF. Renal injury of diet-induced hypercholesterolemia in rats. Kidney Int. 1990;37(3):880–891. doi:10.1038/ki.1990.62
  • Hung CC, Tsai JC, Kuo HT, Chang JM, Hwang SJ, Chen HC. Dyslipoproteinemia and impairment of renal function in diabetic kidney disease: an analysis of animal studies, observational studies, and clinical trials. Rev Diabet Stud. 2013;10(2–3):110–120. doi:10.1900/RDS.2013.10.110
  • Grone HJ, Hohbach J, Grone EF. Modulation of glomerular sclerosis and interstitial fibrosis by native and modified lipoproteins. Kidney Int Suppl. 1996;54:S18–22.
  • Gilbert RE, Cooper ME. The tubulointerstitium in progressive diabetic kidney disease: more than an aftermath of glomerular injury? Kidney Int. 1999;56(5):1627–1637. doi:10.1046/j.1523-1755.1999.00721.x
  • Chen HC, Guh JY, Chang JM, Hsieh MC, Shin SJ, Lai YH. Role of lipid control in diabetic nephropathy. Kidney Int Suppl. 2005;94:S60–2. doi:10.1111/j.1523-1755.2005.09415.x
  • Hirano T. Lipoprotein abnormalities in diabetic nephropathy. Kidney Int Suppl. 1999;71:S22–4. doi:10.1046/j.1523-1755.1999.07106.x