Novel diagnostic approaches and biological therapeutics for intrinsic asthma

References

• MolinaCChronique d’une mort annoncée: la fin de l’asthme intrinsèque. [Predicting death announcement of “intrinsic” asthma.]Bull Acad Natl Méd19901746799805 French2271985
   PubMed Web of Science ®Google Scholar
• RackemannFMA clinical study of one hundred and fifty cases of bronchial asthmaArch Intern Med1918224517522
   Google Scholar
• BhatKDCalhounWJOmalizumab in asthma: is the therapeutic window too small?Chest2011139181021208873
   PubMed Web of Science ®Google Scholar
• HumbertMMenzGYingSThe immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differencesImmunol Today1999201152853310529782
   PubMedGoogle Scholar
• HumbertML’asthme “intrinsèque” existe-til? [Is there such a thing as “intrinsic” asthma?]Rev Mal Respir2000171 Pt 2245254 French10902138
   PubMed Web of Science ®Google Scholar
• HumbertMGrantJATabora-BarataLHigh affinity IgE receptor (FCεRI)-bearing cells in bronchial biopsies from atopic and non-atopic asthmaAm J Respir Crit Care Med19961536 Pt 1193119378665058
   PubMed Web of Science ®Google Scholar
• HumbertMDurhamSRYingSIL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against “intrinsic” asthma being a distinct immunopathologic entityAm J Respir Crit Care Med19961545149715048912771
   PubMed Web of Science ®Google Scholar
• BurrowsBMartinezFDHalonenMBarbeeRAClineMGAssociation of asthma with serum IgE levels and skin-test reactivity to allergensN Engl J Med198932052712772911321
   PubMed Web of Science ®Google Scholar
• SunyerJAntóJMCastellsaguéJSorianoJBRocaJThe Spanish Group of the European Study of AsthmaTotal serum IgE is associated with asthma independently of specific IgE levelsEur Respir J199699188018848880106
   PubMed Web of Science ®Google Scholar
• BeehKMKsollMBuhlRElevation of total serum immunoglobulin E is associated with asthma in nonallergic individualsEur Respir J200016460961411106200
   PubMed Web of Science ®Google Scholar
• HumbertMBronchial immunoglobulin E production in intrinsic asthmaRev Fr Allergol200343229231 French
   Web of Science ®Google Scholar
• YingSHumbertMMengQLocal expression of epsilon germline gene transcripts and RNA for the epsilon heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthmaJ Allergy Clin Immunol2001107468669211295659
   PubMed Web of Science ®Google Scholar
• MouthuyJDetryBSohyCPirsonFPiletteCPresence in sputum of functional dust mite-specific IgE antibodies in intrinsic asthmaAm J Respir Crit Care Med2011184220621421474647
   PubMed Web of Science ®Google Scholar
• BachertCZhangNChronic rhinosinusitis and asthma: novel understanding of the role of IgE ‘above atopy’J Intern Med2012272213314322640264
   PubMed Web of Science ®Google Scholar
• An encyclopedia Britannica company2011 Available from: http://global.britannica.com/EBchecked/topic/455632/phenotypeAccessed June 23, 2014
   Google Scholar
• WenzelSEAsthma: defining of the persistent adult phenotypesLancet2006368953780481316935691
   PubMed Web of Science ®Google Scholar
• HaldarPPavordIDShawDECluster analysis and clinical asthma phenotypesAm J Respir Crit Care Med2008178321822418480428
   PubMed Web of Science ®Google Scholar
• CorrenJAsthma phenotypes and endotypes: an evolving paradigm for classificationDiscov Med2013158324324923636141
   PubMed Web of Science ®Google Scholar
• MooreWCMeyersDAWenzelSEIdentification of asthma phenotypes using cluster analysis in the Severe Asthma Research ProgramAm J Respir Crit Care Med2010181431532319892860
   PubMed Web of Science ®Google Scholar
• SirouxVBasagañaXBoudierAIdentifying adult asthma phenotypes using a clustering approachEur Respir J201138231031721233270
   PubMed Web of Science ®Google Scholar
• de NijsSBVenekampLNBelEHAdult-onset asthma: is it really different?Eur Respir Rev201322127445223457164
   PubMedGoogle Scholar
• RackemannFMA working classification of asthmaAm J Med19473560160620269240
   PubMed Web of Science ®Google Scholar
• WenzelSEAsthma phenotypes: the evolution from clinical to molecular approachesNat Med201218571672522561835
   PubMed Web of Science ®Google Scholar
• JatakanonAUasufCMaziakWLimSChungKFBarnesPJNeutrophilic inflammation in severe persistent asthmaAm J Respir Crit Care Med19991605 Pt 11532153910556116
   PubMed Web of Science ®Google Scholar
• KimHYDeKruyffRHUmetsuDTThe many paths to asthma: phenotype shaped by innate and adaptive immunityNat Immunol201011757758420562844
   PubMed Web of Science ®Google Scholar
• Global Initiative for AsthmaGlobal strategy for asthma management and prevention Available from: http://www.ginasthma.orgAccessed June 6, 2014
   Google Scholar
• GEMA (Spanish Guideline on the Management of Asthma)Arch Bronconeumol200945Suppl 7235
   Google Scholar
• IshizakaKIshizakaTIdentification of gamma-E-antibodies as a carrier of reaginic activityJ Immunol1967996118711984168663
   PubMed Web of Science ®Google Scholar
• ChangTWWuPCHsuCLHungAFAnti-IgE antibodies for the treatment of IgE-mediated allergic diseasesAdv Immunol2007936311917383539
   PubMed Web of Science ®Google Scholar
• RiccioAMDal NegroRWMichelettoCOmalizumab modulates bronchial reticular basement membrane thickness and eosinophil infiltration in severe persistent allergic asthma patientsInt J Immunopathol Pharmacol2012252247548422697079
   PubMed Web of Science ®Google Scholar
• HoshinoMOhtawaJEffects of adding omalizumab, an anti-immunoglobulin E antibody, on airway wall thickening in asthmaRespiration201283652052822236804
   PubMed Web of Science ®Google Scholar
• HumbertMBeasleyRAyresJBenefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATEAllergy200560330931615679715
   PubMed Web of Science ®Google Scholar
• MolimardMde BlayFDidierALe GrosVEffectiveness of omalizumab (Xolair) in the first patients treated in real-life practice in FranceRespir Med20081021717617920257
   PubMed Web of Science ®Google Scholar
• BrusselleGMichilsALouisRDupontL“Real-life” effectiveness of omalizumab in patients with severe persistent allergic asthma: the PERSIST studyRespir Med2009103111633164219619998
   PubMed Web of Science ®Google Scholar
• KornSThielenASeyfriedSTaubeCKornmannOBuhlROmalizumab in patients with severe persistent allergic asthma in a real-life setting in GermanyRespir Med2009103111725173119515548
   PubMed Web of Science ®Google Scholar
• CazzolaMCamiciottoliGBonaviaMItalian real-life experience of omalizumabRespir Med2010104101410141620483574
   PubMed Web of Science ®Google Scholar
• VenneraMCPérez De LlanoLBardagíSSpanish RegistryOmalizumab therapy in severe asthma: experience from the Spanish Registry – some new approachesJ Asthma201249441642222443408
   PubMed Web of Science ®Google Scholar
• European Medicines AgencyXolair Available from: http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000606/human_med_001162.jsp&mid=WC0b01ac058001d124Accessed June 6, 2014
   Google Scholar
• Grimaldi-BensoudaLZureikMAubierMDoes omalizumab make a difference to the real-life treatment of asthma exacerbations? Results from a large cohort of patients with severe uncontrolled asthmaChest2013143239840523505637
   PubMed Web of Science ®Google Scholar
• van den BergeMPauwRGde MonchyJGvan MinnenCAPostmaDSKerstjensHABeneficial effects of treatment with anti-IgE antibodies (omalizumab) in a patient with severe asthma and negative skin-prick test resultsChest2011139119019321208879
   PubMed Web of Science ®Google Scholar
• MenzellaFPiroRFacciolongoNCastagnettiCSimonazziAZucchiLLong-term benefits of omalizumab in a patient with severe non-allergic asthmaAllergy Asthma Clin Immunol201171921609447
   PubMed Web of Science ®Google Scholar
• de LlanoLPVennera MdelCAlvarezFJEffects of omalizumab in non-atopic asthma: results from a Spanish multicenter registryJ Asthma201350329630123350994
   PubMed Web of Science ®Google Scholar
• GarciaGMagnanAChironRA proof of concept randomized-controlled trial of omalizumab in patients with severe difficult to control nonatopic asthmaChest2013144241141923579324
   PubMed Web of Science ®Google Scholar
• BarnesPJIntrinsic asthma: not so different from allergic asthma but driven by superantigens?Clin Exp Allergy20093981145115119538350
   PubMed Web of Science ®Google Scholar
• LommatzschMKornSBuhlRAgainst all odds: anti-IgE for intrinsic asthma?Thorax2014691949623709757
   PubMed Web of Science ®Google Scholar
• PavordIDKornSHowarthPMepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo controlled trialLancet2012380984265165922901886
   PubMed Web of Science ®Google Scholar
• GevaertPVan BruaeneNCattaertTMepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposisJ Allergy Clin Immunol2011128598999521958585
   PubMed Web of Science ®Google Scholar
• OrtegaHChuppGBardinPThe role of mepolizumab in atopic and nonatopic severe asthma with persistent eosinophiliaEur Respir J3232014 [Epub ahead of print.]
   Web of Science ®Google Scholar