Association Between Urinary Parabens and Sperm Quality in Nigerian Men: A Case–Control Study

References

• Vo TT, Yoo YM, Choi KC, Jeung EB. Potential estrogenic effect (s) of parabens at the prepubertal stage of a postnatal female rat model. Reprod Toxicol. 2010;29(3):306–316. doi:10.1016/j.reprotox.2010.01.013
   PubMed Web of Science ®Google Scholar
• Boberg J, Taxvig C, Christiansen S, Hass U. Possible endocrine disrupting effects of parabens and their metabolites. Reprod Toxicol. 2010;30(2):301–312.
   PubMed Web of Science ®Google Scholar
• Guerra MT, Sanabria M, Leite GA, et al. Maternal exposure to butyl paraben impairs testicular structure and sperm quality on male rats. Environ. Toxicol. 2017;32(4):1273–1289. doi:10.1002/tox.22323
   PubMed Web of Science ®Google Scholar
• Zhang L, Dong L, Ding S, et al. Effects of n-butylparaben on steroidogenesis and spermatogenesis through changed E2 levels in male rat offspring. Enviro Toxi Pharmaco. 2014;37(2):705–717. doi:10.1016/j.etap.2014.01.016
   PubMed Web of Science ®Google Scholar
• Oishi S. Effects of butyl paraben on the male reproductive system in mice. Arch Toxicol. 2002;76:423–429. doi:10.1007/s00204-002-0360-8
   PubMed Web of Science ®Google Scholar
• Meeker JD, Yang T, Ye X, Calafat AM, Hauser R. Urinary concentrations of parabens and serum hormone levels, semen quality parameters, and sperm DNA damage. Environ. Health Perspect. 2011;119(2):252–257.
   PubMed Web of Science ®Google Scholar
• Kang KS, Che JH, Ryu DY, Kim TW, Li GX, Lee YS. Decreased sperm number and motile activity on the F1 offspring maternally exposed to butyl p-hydroxybenzoic acid(butyl paraben). J Vet Med Sci. 2002;64(3):227–235. doi:10.1292/jvms.64.227
   PubMed Web of Science ®Google Scholar
• Jurewicz J, Radwan M, Wielgomas B, et al. Human semen quality, sperm DNA damage, and the level of reproductive hormones in relation to urinary concentrations of parabens. J Occup Environ Med. 2017;59(11):1034–1040. doi:10.1097/JOM.0000000000001106
   PubMed Web of Science ®Google Scholar
• Virant-Klun I, Imamovic-Kumalic S, Pinter B. From oxidative stress to male infertility: review of the associations of endocrine-disrupting chemicals (bisphenols, phthalates, and parabens) with human semen quality. Antioxidants. 2022;11(8):1617. doi:10.3390/antiox11081617
   Web of Science ®Google Scholar
• Tavares RS, Martins FC, Oliveira PJ, Ramalho-Santos J, Peixoto FP. Parabens in male infertility—Is there a mitochondrial connection? Reprod Toxicol. 2009;27(1):1–7. doi:10.1016/j.reprotox.2008.10.002
   PubMed Web of Science ®Google Scholar
• Nishihama Y, Toshima H, Yoshinaga J, et al. Paraben exposure and semen quality of Japanese male partners of subfertile couples. Environ. Health Preve Med. 2017;22(1):1–5. doi:10.1186/s12199-017-0618-7
   PubMed Web of Science ®Google Scholar
• Okonofua FE, Ntoimo LF, Omonkhua A, et al. Causes and risk factors for Male infertility: a scoping review of published studies. Int J Gene Med. 2022;4:5985–5997. doi:10.2147/IJGM.S363959
   Google Scholar
• Abarikwu SO. Causes and risk factors for male-factor infertility in Nigeria: a review. Afr J Reproduct Health. 2013;17(4):150–166.
   PubMedGoogle Scholar
• Bolujoko NB, Ogunlaja OO, Alfred MO, et al. Occurrence and human exposure assessment of parabens in water sources in Osun State, Nigeria. Sci Total Envi. 2022;814:152448. doi:10.1016/j.scitotenv.2021.152448
   PubMed Web of Science ®Google Scholar
• Jiménez-Díaz I, Artacho-Cordón F, Vela-Soria F, et al. Urinary levels of bisphenol A, benzophenones and parabens in Tunisian women: a pilot study. Sci Total Envi. 2016;562:81–88. doi:10.1016/j.scitotenv.2016.03.203
   PubMed Web of Science ®Google Scholar
• Uadia PO, Emokpae AM. Male infertility in Nigeria: a neglected reproductive health issue requiring attention. J Bas Clinical Repro Scie. 2015;4(2):45–53. doi:10.4103/2278-960X.161042
   Google Scholar
• Akang EN, Opuwari CS, Enyioma-Alozie S, et al. Trends in semen parameters of infertile men in South Africa and Nigeria. Sci Rep. 2023;13(1):6819. doi:10.1038/s41598-023-33648-4
   PubMed Web of Science ®Google Scholar
• Egbuna C, Amadi CN, Patrick-Iwuanyanwu KC, et al. Emerging pollutants in Nigeria: a systematic review. Enviro Toxi Pharmaco. 2021;85:103638. doi:10.1016/j.etap.2021.103638
   PubMed Web of Science ®Google Scholar
• Okonofua FE, Ntoimo LFC, Unuabonah EI, et al. Association of Urinary Mycotoxins with Sperm Quality: a Case-Control Study in Southern Nigeria. Toxins. 2024;16(3):119. doi:10.3390/toxins16030119
   PubMed Web of Science ®Google Scholar
• WHO. WHO Laboratory Manual for the Examination and Processing of Human Semen. Geneva, Switzerland: World Health Organization; 2021.
   Google Scholar
• Bolujoko NB, Olorunnisola D, Poudel S, et al. Occurrence profiling, risk assessment, and correlations of antimicrobials in surface water and groundwater systems in Southwest Nigeria. Environ Sci. 2024;26(3):595–610.
   Google Scholar
• Adoamnei E, Mendiola J, Moñino-García M, et al. Urinary concentrations of parabens and reproductive parameters in young men. Sci Total Envi. 2018;621:2019. doi:10.1016/j.scitotenv.2017.11.256
   Web of Science ®Google Scholar
• Dodge LE, Williams PL, Williams MA, et al. Paternal urinary concentrations of parabens and other phenols in relation to reproductive outcomes among couples from a fertility clinic. Environ. Health Perspect. 2015;123(7):665–671. doi:10.1289/ehp.1408605
   PubMed Web of Science ®Google Scholar
• Joensen UN, Jørgensen N, Thyssen JP, et al. Urinary excretion of phenols, parabens and benzophenones in young men: associations to reproductive hormones and semen quality are modified by mutations in the Filaggrin gene. Environ. Int. 2018;121:365–374. doi:10.1016/j.envint.2018.09.020
   PubMed Web of Science ®Google Scholar
• Shen X, Zhan M, Wang Y, Tang W, Zhang Q, Zhang J. Exposure to parabens and semen quality in reproductive-aged men. Ecotoxicol Environ Saf. 2023;264:115453. doi:10.1016/j.ecoenv.2023.115453
   PubMed Web of Science ®Google Scholar
• Bloom MS, Whitcomb BW, Chen Z, Ye A, Kannan K, Buck Louis GM. Associations between urinary phthalate concentrations and semen quality parameters in a general population. Hum Reprod. 2015;30(11):2645–2657. doi:10.1093/humrep/dev219
   PubMed Web of Science ®Google Scholar
• Abou Ghayda R, Williams PL, Chavarro JE, et al. Urinary bisphenol S concentrations: potential predictors of and associations with semen quality parameters among men attending a fertility center. Environ. Int. 2019;131:105050. doi:10.1016/j.envint.2019.105050
   PubMed Web of Science ®Google Scholar
• Yu L, Peng F, Yuan D, et al. Correlation study of parabens in urine, serum, and seminal plasma of adult men in Beijing, China. Environ. Sci. Pollut. Res. 2021;28:41120–41126. doi:10.1007/s11356-021-13625-y
   PubMed Web of Science ®Google Scholar
• Wang YX, Liu C, Chen YJ, et al. Predictors and correlations of phthalate metabolite concentrations in urine and seminal plasma among reproductive-aged men. Environ. Res. 2018;161:336–344. doi:10.1016/j.envres.2017.11.027
   PubMed Web of Science ®Google Scholar
• Scinicariello F, Buser MC. Serum testosterone concentrations and urinary bisphenol A, benzophenone-3, triclosan, and paraben levels in male and female children and adolescents: NHANES 2011–2012. Environ. Health Perspect. 2016;124(12):1898–1904. doi:10.1289/EHP150
   PubMed Web of Science ®Google Scholar