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Clinical Neurology

Unraveling the Predictors of Enlarged Perivascular Spaces: A Comprehensive Logistic Regression Approach in Cerebral Small Vessel Disease

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Pages 2513-2525 | Received 22 Mar 2024, Accepted 28 May 2024, Published online: 31 May 2024

References

  • Wardlaw JM, Smith EE, Biessels GJ, et al. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol. 2013;12(8):822–838. doi:10.1016/S1474-4422(13)70124-8
  • Duering M, Biessels GJ, Brodtmann A, et al. Neuroimaging standards for research into small vessel disease-advances since 2013. Lancet Neurol. 2023;22(7):602–618. doi:10.1016/S1474-4422(23)00131-X
  • Mestre H, Kostrikov S, Mehta RI, Nedergaard M. Perivascular spaces, glymphatic dysfunction, and small vessel disease. Clin Sci. 2017;131(17):2257–2274. doi:10.1042/CS20160381
  • Raposo N, Viswanathan A. MRI-visible enlarged perivascular spaces: beyond microbleeds to predict intracerebral hemorrhage. Neurology. 2020;95(16):709–710. doi:10.1212/WNL.0000000000010790
  • Delgado-Alvarado M, Gutiérrez-González A, Marques-Llano S, Riancho J. Parkinsonism associated with striatal enlarged perivascular spaces. Neurology. 2022;98(21):892–893. doi:10.1212/WNL.0000000000200547
  • Lin F, Yang B, Chen Y, Zhao W, Li B, Jia W. Enlarged perivascular spaces are linked to freezing of gait in Parkinson’s disease. Front Neurol. 2022;13:985294. doi:10.3389/fneur.2022.985294
  • Lynch M, Pham W, Sinclair B, O’Brien TJ, Law M, Vivash L. Perivascular spaces as a potential biomarker of Alzheimer’s disease. Front Neurosci. 2022;16:1021131. doi:10.3389/fnins.2022.1021131
  • Ramaswamy S, Khasiyev F, Gutierrez J. Brain enlarged perivascular spaces as imaging biomarkers of cerebrovascular disease: a clinical narrative review. J Am Heart Assoc. 2022;11(24):e026601. doi:10.1161/JAHA.122.026601
  • Wang ML, Sun Z, Li WB, et al. Enlarged perivascular spaces and white matter hyperintensities in patients with frontotemporal lobar degeneration syndromes. Front Aging Neurosci. 2022;14:923193. doi:10.3389/fnagi.2022.923193
  • Hicks AJ, Sinclair B, Shultz SR, et al. Associations of enlarged perivascular spaces with brain lesions, brain age, and clinical outcomes in chronic traumatic brain injury. Neurology. 2023;101(1):e63–e73. doi:10.1212/WNL.0000000000207370
  • Wardlaw JM, Benveniste H, Nedergaard M, et al. Perivascular spaces in the brain: anatomy, physiology and pathology. Nat Rev Neurol. 2020;16(3):137–153. doi:10.1038/s41582-020-0312-z
  • Bennette C, Vickers A. Against quantiles: categorization of continuous variables in epidemiologic research, and its discontents. BMC Med Res Methodol. 2012;12:21. doi:10.1186/1471-2288-12-21
  • Barrio I, Arostegui I, Rodríguez-álvarez M-X, Quintana J-M. A new approach to categorising continuous variables in prediction models: proposal and validation. Stat Methods Med Res. 2017;26(6):2586–2602. doi:10.1177/0962280215601873
  • Li T, Huang Y, Cai W, et al. Age-related cerebral small vessel disease and inflammaging. Cell Death Dis. 2020;11(10):932. doi:10.1038/s41419-020-03137-x
  • Markus HS, Erik de Leeuw F. Cerebral small vessel disease: recent advances and future directions. Int J Stroke. 2023;18(1). doi:10.1177/17474930221144911
  • Klarenbeek P, van Oostenbrugge RJ, Lodder J, Rouhl RPW, Knottnerus ILH, Staals J. Higher ambulatory blood pressure relates to enlarged Virchow-Robin spaces in first-ever lacunar stroke patients. J Neurol. 2013;260(1):115–121. doi:10.1007/s00415-012-6598-z
  • Gao Y, Deng WP, Sun JL, et al. The association of nocturnal blood pressure patterns and other influencing factors with lacunes and enlarged perivascular spaces in hypertensive patients. Front Neurol. 2022;2022:13.
  • Di Fusco SA, Arca M, Scicchitano P, et al. Lipoprotein(a): a risk factor for atherosclerosis and an emerging therapeutic target. Heart. 2022;109(1):18–25. doi:10.1136/heartjnl-2021-320708
  • Lampsas S, Xenou M, Oikonomou E, et al. Lipoprotein(a) in atherosclerotic diseases: from pathophysiology to diagnosis and treatment. Molecules. 2023;28(3). doi:10.3390/molecules28030969
  • Yang SN, Zhang XY, Yuan JL, Yin JM, Hu WL. Serum uric acid is independently associated with enlarged perivascular spaces. Sci Rep. 2017;7:1.
  • Deveci B, Gazi E. Relation between globulin, fibrinogen, and albumin with the presence and severity of coronary artery disease. Angiology. 2021;72(2):174–180. doi:10.1177/0003319720959985
  • Chen L, Xu M, Huang Q, Liu Y, Ren W. Clinical significance of albumin to globulin ratio among patients with stroke-associated pneumonia. Front Nutrit. 2022;9:970573. doi:10.3389/fnut.2022.970573