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Original Research

A novel therapeutic strategy for cartilage diseases based on lipid nanoparticle-RNAi delivery system

, , , , , , , & show all
Pages 617-631 | Published online: 31 Jan 2018

References

  • Centers for Disease Control and Prevention (CDC)Prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation–United States, 2010–2012MMWR Morb Mortal Wkly Rep2013624486987324196662
  • LinACSeetoBLBartoszkoJMModulating hedgehog signaling can attenuate the severity of osteoarthritisNat Med200915121421142519915594
  • PalmerAJBrownCPMcNallyEGNon-invasive imaging of cartilage in early osteoarthritisBone Joint J201395-B673874623723266
  • StrombeckBPeterssonIFVliet VlielandTPEUMUSC.net WP6 groupHealth care quality indicators on the management of rheumatoid arthritis and osteoarthritis: a literature reviewRheumatology (Oxford)201352238239023086518
  • IagnoccoANaredoEOsteoarthritis: research update and clinical applicationsRheumatology (Oxford)201251Suppl 7vii2vii523230089
  • BrandtKDDieppePRadinEEtiopathogenesis of osteoarthritisMed Clin North Am2009931124xv19059018
  • WeiFZhouJWeiXActivation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilageOsteoarthritis Cartilage201220775576322469853
  • ZhangCWeiXChenCIndian hedgehog in synovial fluid is a novel marker for early cartilage lesions in human knee jointInt J Mol Sci20141557250726524786088
  • ZhouJChenQLanskeBDisrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreERT2; Ihhfl/fl miceArthritis Res Ther2014161R1124428864
  • CoventrySKapurRPSiebertJRCyclopamine-induced holoprosencephaly and associated craniofacial malformations in the golden hamster: anatomic and molecular eventsPediatr Dev Pathol199811294110463269
  • LipinskiRJDenglerEKiehnMPetersonREBushmanWIdentification and characterization of several dietary alkaloids as weak inhibitors of hedgehog signalingToxicol Sci2007100245646317728282
  • KimuraHNgJMCurranTTransient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structureCancer Cell200813324926018328428
  • LipinskiRJHutsonPRHannamPWDose- and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouseToxicol Sci2008104118919718411234
  • Lopez-FragaMMartinezTJimenezARNA interference technologies and therapeutics: from basic research to productsBioDrugs200923530533219754220
  • YonezawaHAokiTFurusawaADemonstration of a quantum teleportation network for continuous variablesNature2004431700743043315386006
  • ZhangGGuoBWuHA delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapyNat Med201218230731422286306
  • PignatelloRSarpietroMGCastelliFSynthesis and biological evaluation of a new polymeric conjugate and nanocarrier with osteotropic propertiesJ Funct Biomater201231799924956517
  • CrawfordRDogdasBKeoughEAnalysis of lipid nanoparticles by Cryo-EM for characterizing siRNA delivery vehiclesInt J Pharm20114031–223724420974237
  • BelliveauNMHuftJLinPJMicrofluidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNAMol Ther Nucleic Acids20121e3723344179
  • SempleSCAkincAChenJRational design of cationic lipids for siRNA deliveryNat Biotechnol201028217217620081866
  • LiangCGuoBWuHAptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategyNat Med201521328829425665179
  • ArandaR4thDineenSMCraigRLGuerrieriRARobertsonJMComparison and evaluation of RNA quantification methods using viral, prokaryotic, and eukaryotic RNA over a 10(4) concentration rangeAnal Biochem2009387112212719454255
  • WeiLSunXKanbeKChondrocyte death induced by pathological concentration of chemokine stromal cell-derived factor-1J Rheumatol20063391818182616960943
  • WangSWeiXZhouJIdentification of alpha2-macroglobulin as a master inhibitor of cartilage-degrading factors that attenuates the progression of posttraumatic osteoarthritisArthritis Rheumatol20146671843185324578232
  • JayasuriyaCTZhouFHPeiMMatrilin-3 chondrodysplasia mutations cause attenuated chondrogenesis, premature hypertrophy and aberrant response to TGF-beta in chondroprogenitor cellsInt J Mol Sci2014158145551457325196597
  • HunterDJZhangYQTuXChange in joint space width: hyaline articular cartilage loss or alteration in meniscus?Arthritis Rheum20065482488249516868968
  • PetersonJDLabrancheTPVasquezKOOptical tomographic imaging discriminates between disease-modifying anti-rheumatic drug (DMARD) and non-DMARD efficacy in collagen antibody-induced arthritisArthritis Res Ther2010123R10520509880
  • ThomasNPLiPFlemingBCAttenuation of cartilage pathogenesis in post-traumatic osteoarthritis (PTOA) in mice by blocking the stromal derived factor 1 receptor (CXCR4) with the specific inhibitor, AMD3100J Orthop Res20153371071107825732515
  • JayGDFlemingBCWatkinsBAPrevention of cartilage degeneration and restoration of chondroprotection by lubricin tribosupple-mentation in the rat following anterior cruciate ligament transectionArthritis Rheum20106282382239120506144
  • PritzkerKPGaySJimenezSAOsteoarthritis cartilage histopathology: grading and stagingOsteoarthritis Cartilage2006141132916242352
  • WeiLFlemingBCSunXComparison of differential biomarkers of osteoarthritis with and without posttraumatic injury in the Hartley guinea pig modelJ Orthop Res201028790090620108346
  • TallhedenTBengtssonCBrantsingCProliferation and differentiation potential of chondrocytes from osteoarthritic patientsArthritis Res Ther200573R560R56815899043
  • GarberKAlnylam’s RNAi therapy targets amyloid diseaseNat Biotechnol2015336577
  • DyawanapellySGhodkeSBVishwanathanRDandekarPJainRRNA interference-based therapeutics: molecular platforms for infectious diseasesJ Biomed Nanotechnol20141091998203725992447
  • WermkeMCamgozAPaszkowski-RogaczMRNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates fasudil as an antileukemic drugBlood2015125243760376825931586
  • KanedaMMSasakiYLanzaGMMilbrandtJWicklineSAMechanisms of nucleotide trafficking during siRNA delivery to endothelial cells using perfluorocarbon nanoemulsionsBiomaterials201031113079308620092889
  • XueHYNarvikarMZhaoJBWongHLLipid encapsulation of cationic polymers in hybrid nanocarriers reduces their non-specific toxicity to breast epithelial cellsPharm Res201330257258323135818
  • SoutoEBNayakAPMurthyRSLipid nanoemulsions for anti-cancer drug therapyPharmazie201166747347821812320
  • YanagishitaMPodyma-InoueKAYokoyamaMExtraction and separation of proteoglycansGlycoconj J200926895395918493850