137
Views
38
CrossRef citations to date
0
Altmetric
Original Research

Development of coated liposomes loaded with ghrelin for nose-to-brain delivery for the treatment of cachexia

, , , , , & show all
Pages 8531-8543 | Published online: 28 Nov 2017

References

  • Editors of the American Heritage DictionariesThe American Heritage Medical DictionaryBostonHoughton Mifflin2007
  • DeBoerMDEmergence of ghrelin as a treatment for cachexia syndromesNutrition200824980681418725076
  • ArgilésJMStemmlerBThe potential of ghrelin in the treatment of cancer cachexiaExpert Opin Biol Ther2013131677623078025
  • GarciaJYanYManning-DuusEFriendJEffects of the ghrelin receptor agonist anamorelin on lean body mass in cancer patients with cachexia; results from a Phase II randomized, double blind, multicenter studyCancer Metab20142Suppl 1P19
  • HorvathTLDianoSSotonyiPHeimanMTschöpMMinireview: Ghrelin and the regulation of energy balance – a hypothalamic perspectiveEndocrinology2001142104163416911564668
  • KojimaMHosodaHDateYNakazatoMMatsuoHKangawaKGhrelin is a growth-hormone-releasing acylated peptide from stomachNature1999402676265666010604470
  • BanksWATschöpMRobinsonSMHeimanMLExtent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structureJ Pharmacol Exp Ther2002302282282712130749
  • BarshGSSchwartzMWGenetic approaches to studying energy balance: perception and integrationNat Rev Genet20023858960012154382
  • AkamizuTKangawaKGhrelin for cachexiaJ Cachexia Sarcopenia Muscle20101216917621475698
  • BrimijoinSChenVPPangYPGengLGaoYPhysiological roles for butyrylcholinesterase: a BChE-ghrelin axisChem Biol Interact2016259Pt B27127526915976
  • AkamizuTTakayaKIrakoTPharmacokinetics, safety, and endocrine and appetite effects of ghrelin administration in young healthy subjectsEur J Endocrinol2004150444745515080773
  • ThorneRGEmoryCRAlaTAFreyWHQuantitative analysis of the olfactory pathway for drug delivery to the brainBrain Res19956921–22782828548316
  • SchipperNMVerhoefJCMerkusFHThe nasal mucociliary clearance: relevance to nasal drug deliveryPharm Res1991878078141924131
  • MoellerEHHolstBNielsenLHPedersenPSØstergaardJStability, liposome interaction, and in vivo pharmacology of ghrelin in liposomal suspensionsInt J Pharm20103901131819505544
  • GrafSGarciaJAnamorelin hydrochloride in the treatment of cancer anorexia-cachexia syndrome: design, development, and potential place in therapyDrug Des Devel Ther20171123252331
  • GarinMCBurnsCMKaulSCappolaARThe human experience with ghrelin administrationJ Clin Endocrinol Metab20139851826183723533240
  • AzegamiTYukiYSawadaSNanogel-based nasal ghrelin vaccine prevents obesityMucosal Immunol20171051351136028120848
  • ZollersBRhodesLHeinenECapromorelin oral solution (ENTYCE) increases food consumption and body weight when administered for 4 consecutive days to healthy adult beagle dogs in a randomized, masked, placebo controlled studyBMC Vet Res20171311028056951
  • TemelJSAbernethyAPCurrowDCAnamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trialsLancet Oncol201617451953126906526
  • MiglioreMMVyasTKCampbellRBAmijiMMWaszczakBLBrain delivery of proteins by the intranasal route of administration: a comparison of cationic liposomes versus aqueous solution formulationsJ Pharm Sci20109941745176119774660
  • SalamaHAMahmoudAAKamelAOHadyMAAwadGAPhospholipid based colloidal poloxamer-nanocubic vesicles for brain targeting via the nasal routeColloids Surfaces B Biointerfaces201210014615422766291
  • IllumLFarrajNFDavisSSChitosan as a novel nasal delivery system for peptide drugsPharm Res1994118118611897971722
  • Van WoenselMWauthozNRosièreRDevelopment of siRNA-loaded chitosan nanoparticles targeting galectin-1 for the treatment of glioblastoma multiforme via intranasal administrationJ Control Release2016227718126902800
  • Filipović-GrcićJSkalko-BasnetNJalsenjakIMucoadhesive chitosan-coated liposomes: characteristics and stabilityJ Microencapsul2008181312
  • StaesERozetEUčakarBHubertPPréatVValidation of a method for the quantitation of ghrelin and unacylated ghrelin by HPLCJ Pharm Biomed Anal201051363363919875264
  • BanghamADProperties and uses of lipid vesicles: an overviewAnn N Y Acad Sci197830827279288
  • ZakandaFNLinsLNottKPaquotMLeloGMDeleuMInteraction of hexadecylbetainate chloride with biological relevant lipidsLangmuir20122873524353322263671
  • HeerklotzHSeeligJTitration calorimetry of surfactant-membrane partitioning and membrane solubilizationBiochim Biophys Acta200015081–2698511090819
  • RazafindralamboHDufourSPaquotMDeleuMThermodynamic studies of the binding interactions of surfactin analogues to lipid vesiclesJ Therm Anal Calorim2009953817821
  • MantleMAllenAA colorimetric assay for glycoproteins based on the periodic acid/Schiff stainBiochem Soc Trans197863607609208893
  • TamilvananSPharmaceutical Manufacturing Handbook: Production and ProcessesHoboken (NJ)Wiley2008
  • EricksonJDetermination of the concentration of caffeine, theobromine, and gallic acid in commercial tea samplesConcordia Coll J Anal Chem201123135
  • ShahRBSiddiquiAShahGKhanMAA validated HPLC assay for simultaneous analysis of salmon calcitonin and duck ovomucoidPharmazie200358962062214531455
  • HosodaHDoiKNagayaNOptimum collection and storage conditions for ghrelin measurements: octanoyl modification of ghrelin is rapidly hydrolyzed to desacyl ghrelin in blood samplesClin Chem20045061077108015161728
  • MinCOhtaKKajiyaMThe antimicrobial activity of the appetite peptide hormone ghrelinPeptides201236215115622634233
  • SeeligJThermodynamics of lipid-peptide interactionsBiochim Biophys Acta200416661–2405015519307
  • StaesEAbsilPALinsLAcylated and unacylated ghrelin binding to membranes and to ghrelin receptor: towards a better understanding of the underlying mechanismsBiochim Biophys Acta20101798112102211320637180
  • ØstergaardJMoellerEHGhrelin-liposome interactions: characterization of liposomal formulations of an acylated 28-amino acid peptide using CEElectrophoresis201031233934520024925
  • MargolisFLGetchellTVMolecular Neurobiology of the Olfactory System: Molecular, Membranous, and Cytological StudiesHeidelbergSpringer2013
  • DahlARHadleyWMNasal cavity enzymes involved in xenobiotic metabolism: effects on the toxicity of inhalantsCrit Rev Toxicol19912153453721741949
  • SarkarMADrug metabolism in the nasal mucosaPharm Res199291191589391
  • MorimotoKMiyazakiMKakemiMEffects of proteolytic enzyme inhibitors on nasal absorption of salmon calcitonin in ratsInt J Pharm1995113118
  • LewisJLNikulaKJNovakRDahlARComparative localization of carboxylesterase in F344 rat, beagle dog, and human nasal tissueAnat Rec1994239155648037378
  • BogdanffyMTaylorMKinetics of nasal carboxylesterase-mediated metabolism of vinyl acetateDrug Metab Dispos1993216110711117905391
  • OlsenJVOngSEMannMTrypsin cleaves exclusively C-terminal to arginine and lysine residuesMol Cell Proteomics20043660861415034119
  • TaylorMSHwangYHsiaoPYBoekeJDColePAGhrelin O-acyltransferase assays and inhibitionMethods Enzymol201251420522822975055
  • ChoderaJDMobleyDLEntropy-enthalpy compensation: role and ramifications in biomolecular ligand recognition and designAnnu Rev Biophys20134212114223654303
  • CasettariLIllumLChitosan in nasal delivery systems for therapeutic drugsJ Control Release201419018920024818769
  • ChannarongSChaicumpaWSinchaipanidNMitrevejADevelopment and evaluation of chitosan-coated liposomes for oral DNA vaccine: the improvement of Peyer’s patch targeting using a polyplex-loaded liposomesAAPS Pharm Sci Tech2011121192200
  • MadyMMDarwishMMEffect of chitosan coating on the characteristics of DPPC liposomesJ Adv Res201013187191
  • GuoJPingQJiangGHuangLTongYChitosan-coated liposomes: characterization and interaction with leuprolideInt J Pharm2003260216717312842337
  • WenZYanZHeRBrain targeting and toxicity study of odorranalectin-conjugated nanoparticles following intranasal administrationDrug Deliv201118855556121812752
  • Amoako-TuffourMYeungPAguRPermeation of losartan across human respiratory epithelium: an in vitro study with Calu-3 cellsActa Pharm200959439540519919929
  • YangTHussainAPaulsonJAbbruscatoTJAhsanFCyclodextrins in nasal delivery of low-molecular-weight heparins: in vivo and in vitro studiesPharm Res20042171127113615290851
  • UngellALAndreassonALundinKUtterLEffects of enzymatic inhibition and increased paracellular shunting on transport of vasopressin analogues in the ratJ Pharm Sci19928176406451403696
  • Torres-LugoMGarcíaMRecordRPeppasNApH-sensitive hydrogels as gastrointestinal tract absorption enhancers: transport mechanisms of salmon calcitonin and other model molecules using the Caco-2 cell modelBiotechnol Prog200218361261612052080
  • PrueksaritanontTDeLunaPGorhamLMIn vitro and in vivo evaluations of intestinal barriers for the zwitterion L-767,679 and its carboxyl ester prodrug L-775,318: roles of efflux and metabolismDrug Metab Dispos19982665205279616186
  • RibeiroJASebastiãoAMCaffeine and adenosineJ Alzheimers Dis201020Suppl 1S3S1520164566
  • BecskeiCRiedigerTZündDWookeyPLutzTAImmunohistochemical mapping of calcitonin receptors in the adult rat brainBrain Res20041030222123315571671
  • PregoCTorresDAlonsoMJChitosan nanocapsules: a new carrier for nasal peptide deliveryJ Drug Deliv Sci Technol2006165331337
  • HuangMKhorELimLYUptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylationPharm Res200421234435315032318
  • CarlstedtILindgrenHSheehanJKUlmstenUWingerupLIsolation and characterization of human cervical-mucus glycoproteinsBiochem J1983211113226409086
  • KhutoryanskiyVVAdvances in mucoadhesion and mucoadhesive polymersMacromol Biosci201111674876421188688
  • NaikANairHFormulation and evaluation of thermosensitive biogels for nose to brain delivery of doxepinBiomed Res Int2014201484754725032225
  • SurberCElsnerPFarageMATopical Applications and the MucosaBasel, SwitzerlandKarger2011
  • SeCMInthavongKTuJYUnsteady particle deposition in a human nasal cavity2009 Available from: http://www.cfd.com.au/cfd_conf09/PDFs/016SE.pdfAccessed March 27, 2017
  • FrankDOKimbellJSPawarSRheeJSEffects of anatomy and particle size on nasal sprays and nebulizersOtolaryngol Head Neck Surg2012146231331922049020
  • HarrisASSvenssonEWagnerZGLethagenSNilssonIMEffect of viscosity on particle size, deposition, and clearance of nasal delivery systems containing desmopressinJ Pharm Sci19887754054083411462
  • PenningtonJPandeyPTatHWillsonJDonovanBSpray pattern and droplet size analyses for high-shear viscosity determination of aqueous suspension corticosteroid nasal spraysDrug Dev Ind Pharm200834992392918800252