339
Views
200
CrossRef citations to date
0
Altmetric
Original Research

Engineered exosome-mediated delivery of functionally active miR-26a and its enhanced suppression effect in HepG2 cells

, , , , &
Pages 585-599 | Published online: 30 Jan 2018

References

  • NiidomeTHuangLGene therapy progress and prospects: nonviral vectorsGene Ther20029241647165212457277
  • LeeSJKimMJKwonICRobertsTMDelivery strategies and potential targets for siRNA in major cancer typesAdv Drug Deliv Rev201610421527259398
  • LiangGLiYFengWPolyethyleneimine-coated quantum dots for miRNA delivery and its enhanced suppression in HepG2 cellsInt J Nanomedicine2016116079608827895481
  • Alvarez-ErvitiLSeowYYinHBettsCLakhalSWoodMJDelivery of siRNA to the mouse brain by systemic injection of targeted exosomesNat Biotechnol201129434134521423189
  • DaiLGuNChenBAMarriottGHuman platelets repurposed as vehicles for in vivo imaging of myeloma xenotransplantsOncotarget2016716210762109027049725
  • MarriottGEngineering platelets for tumour targetingAging (Albany NY)2016881572157327508429
  • LiJSharkeyCCWunBLiesveldJLKingMRGenetic engineering of platelets to neutralize circulating tumor cellsJ Control Release2016228384726921521
  • ShiJKundratLPisheshaNEngineered red blood cells as carriers for systemic delivery of a wide array of functional probesProc Natl Acad Sci U S A201411128101311013624982154
  • DenzerKKleijmeerMJHeijnenHFStoorvogelWGeuzeHJExosome: from internal vesicle of the multivesicular body to intercellular signaling deviceJ Cell Sci20001133365337410984428
  • FuhrmannGHerrmannIKStevensMMCell-derived vesicles for drug therapy and diagnostics: opportunities and challengesNano Today201510339740928458718
  • EckardSCRiceGIFabreAThe SKIV2L RNA exosome limits activation of the RIG-I-like receptorsNat Immunol201415983984525064072
  • GidlofOvan der BrugMOhmanJPlatelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expressionBlood201312193908391723493781
  • KarantalisVHareJMUse of mesenchymal stem cells for therapy of cardiac diseaseCirc Res201511681413143025858066
  • PowersSPollackREInducing stable reversion to achieve cancer controlNat Rev Cancer201616426627027458638
  • TianTZhuYLZhouYYExosome uptake through clathrin-mediated endocytosis and macropinocytosis and mediating miR-21 deliveryJ Biol Chem201428932222582226724951588
  • GhaiVWangKRecent progress toward the use of circulating micro RNAs as clinical biomarkersArch Toxicol201690122959297827585665
  • LeeCCarneyRPHazariS3D plasmonic nanobowl platform for the study of exosomes in solutionNanoscale20157209290929725939587
  • TianYLiSSongJA doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapyBiomaterials20143572383239024345736
  • KalraHAddaCGLiemMComparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasmaProteomics201313223354336424115447
  • RanaSMalinowskaKZoellerMExosomal tumor microRNA modulates premetastatic organ cellsNeoplasia201315328129523479506
  • DidiotMCHallLMColesAHExosome-mediated delivery of hydrophobically modified siRNA for huntingtin mRNA silencingMol Ther201624101836184727506293
  • MorishitaMTakahashiYMatsumotoANishikawaMTakakuraYExosome-based tumor antigens-adjuvant co-delivery utilizing genetically engineered tumor cell-derived exosomes with immunostimulatory CpG DNABiomaterials2016111556527723556
  • O’ConnorRMGururajanADinanTGKennyPJCryanJFAll roads lead to the miRNome: miRNAs Have a central role in the molecular pathophysiology of psychiatric disordersTrends Pharmacol Sci201637121029104427832923
  • KortylewskiMNechaevSHow to train your dragon: targeted delivery of MicroRNA to cancer cells in vivoMol Ther20142261070107124881764
  • RinconMYVandenDriesscheTChuahMKGene therapy for cardiovascular disease: advances in vector development, targeting, and delivery for clinical translationCardiovasc Res2015108142026239654
  • HatakeyamaHMurataMSatoYThe systemic administration of an anti-miRNA oligonucleotide encapsulated pH-sensitive liposome results in reduced level of hepatic microRNA-122 in miceJ Control Release20141731435024511611
  • ScomparinAPolyakDKrivitskyASatchi-FainaroRAchieving successful delivery of oligonucleotides – From physico-chemical characterization to in vivo evaluationBiotechnol Adv2015336 Pt 31294130925916823
  • KheirolomoomAKimCWSeoJWMultifunctional nanoparticles facilitate molecular targeting and miRNA delivery to inhibit atherosclerosis in ApoE(−/−) miceAcs Nano2015998885889726308181
  • ChenFHuangPZhuYJWuJZhangCLCuiDXThe photoluminescence, drug delivery and imaging properties of multifunctional Eu3+/Gd3+ dual-doped hydroxyapatite nanorodsBiomaterials201132349031903921875748
  • KotaJChivukulaRRO’DonnellKATherapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer modelCell200913761005101719524505
  • LiangGZhuYJingACationic microRNA-delivering nanocarriers for efficient treatment of colon carcinoma in xenograft modelGene Ther2016231282983827482839
  • UrbanSZiesenissSWerderMHauserHBudzinskiREngelmannBScavenger receptor BI transfers major lipoprotein-associated phospholipids into the cellsJ Biol Chem200027543334093341510938082
  • YamamotoSFukuharaTOnoCLipoprotein receptors redundantly participate in entry of hepatitis C virusPLoS Pathog2016125e100561027152966
  • KharazihaPChioureasDRutishauserDMolecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxelOncotarget2015625217402175425844599
  • LazarIClementEDucoux-PetitMProteome characterization of melanoma exosomes reveals a specific signature for metastatic cell linesPigment Cell Melanoma Res201528446447525950383
  • YimNRyuSWChoiKExosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction moduleNat Commun201671227727447450
  • HungMELeonardJNStabilization of exosome-targeting peptides via engineered glycosylationJ Biol Chem2015290138166817225657008
  • MoZCRenKLiuXTangZLYiGHA high-density lipoprotein-mediated drug delivery systemAdv Drug Deliv Rev2016106Pt A13214727208399
  • KanadaMBachmannMHHardyJWDifferential fates of biomolecules delivered to target cells via extracellular vesiclesProc Natl Acad Sci U S A201511212E1433E144225713383
  • LunavatTRJangSCNilssonLRNAi delivery by exosome-mimetic nanovesicles - Implications for targeting c-Myc in cancerBiomaterials201610223123827344366
  • ChenLZhengJZhangYTumor-specific expression of MicroRNA-26a suppresses human hepatocellular carcinoma growth via cyclin-dependent and -independent pathwaysMol Ther20111981521152821610700
  • GandhiNSTekadeRKChouguleMBNanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: current progress and advancesJ Control Release201419423825625204288
  • TkachMTheryCCommunication by extracellular vesicles: where we are and where we need to goCell201616461226123226967288
  • MalhotraHSheokandNKumarSExosomes: tunable nano vehicles for macromolecular delivery of transferrin and lactoferrin to specific intracellular compartmentJ Biomed Nanotechnol20161251101111427305829
  • ChoiJSYoonHILeeKSExosomes from differentiating human skeletal muscle cells trigger myogenesis of stem cells and provide biochemical cues for skeletal muscle regenerationJ Control Release201622210711526699421
  • TianYLiSSongJA doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapyBiomaterials20143572383239024345736
  • MartinezLOJacquetSEsteveJPEctopic beta-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosisNature20034216918757912511957
  • TominagaNYoshiokaYOchiyaTA novel platform for cancer therapy using extracellular vesiclesAdv Drug Deliv Rev201595505526482189
  • JoWKimJYoonJLarge-scale generation of cell-derived nanovesiclesNanoscale2014620120561206425189198