Physiologically based pharmacokinetic modeling of nanoceria systemic distribution in rats suggests dose- and route-dependent biokinetics

References

• SunCWLiHChenLQNanostructured ceria-based materials: synthesis, properties, and applicationsEnergy Environ Sci20125984758505
   Web of Science ®Google Scholar
• MelchionnaMFornasieroPThe role of ceria-based nanostructured materials in energy applicationsMater Today2014177349357
   Web of Science ®Google Scholar
• CasseeFRvan BalenECSinghCExposure, health and ecological effects review of engineered nanoscale cerium and cerium oxide associated with its use as a fuel additiveCrit Rev Toxicol201141321322921244219
   PubMed Web of Science ®Google Scholar
• CastanoCEO’KeefeMJFahrenholtzWGCerium-based oxide coatingsCurr Opin Solid State Mater20151926976
   Web of Science ®Google Scholar
• CelardoIPedersenJZTraversaEGhibelliLPharmacological potential of cerium oxide nanoparticlesNanoscale2011341411142021369578
   PubMed Web of Science ®Google Scholar
• RoccaAMoscatoSRoncaFPilot in vivo investigation of cerium oxide nanoparticles as a novel anti-obesity pharmaceutical formulationNanomedicine20151171725173426003299
   PubMed Web of Science ®Google Scholar
• WalkeyCDasSSealSCatalytic properties and biomedical applications of cerium oxide nanoparticlesEnviron Sci Nano201521335326207185
   PubMed Web of Science ®Google Scholar
• ChigurupatiSMughalMROkunEEffects of cerium oxide nanoparticles on the growth of keratinocytes, fibroblasts and vascular endothelial cells in cutaneous wound healingBiomaterials20133492194220123266256
   PubMed Web of Science ®Google Scholar
• ZhouXHWongLLKarakotiASSealSMcGinnisJFNanoceria inhibit the development and promote the regression of pathologic retinal neovascularization in the Vldlr knockout mousePLoS One201162e1673321364932
   PubMed Web of Science ®Google Scholar
• KwonHJChaMYKimDMitochondria-targeting ceria nanoparticles as antioxidants for Alzheimer’s diseaseACS Nano20161022860287026844592
   PubMed Web of Science ®Google Scholar
• Integrated laboratory Systems (ILS)Chemical information profile for ceric oxide [CAS No. 1306-38-3]. Supporting Nomination for Toxicological Evaluation by the National Toxicology Program2006 Available from: http://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ceric_oxide2_508.pdfAccessed March 12, 2018
   Google Scholar
• Organisation for Economic Co-operation and Development (OECD)List of manufactured nanomaterials and list of endpoints for phase one of the sponsorship programme for the testing of manufactured nanomaterials: revision2010 http://www.oecd.org/officialdocuments/publicdisplaydocumentpdf/?cote=env/jm/mono(2010)46&doclanguage=enAccessed March 12, 2018
   Google Scholar
• GeraetsLOomenAGSchroeterJDColemanVACasseeFRTissue distribution of inhaled micro- and nano-sized cerium oxide particles in rats: results from a 28-day exposure studyToxicol Sci2012127246347322430073
   PubMed Web of Science ®Google Scholar
• MolinaRMKonduruNVJimenezRJBioavailability, distribution and clearance of tracheally instilled, gavaged or injected cerium dioxide nanoparticles and ionic ceriumEnviron Sci Nano201416561573
   Web of Science ®Google Scholar
• YokelRAAuTCMacPhailRDistribution, elimination, and biopersistence to 90 days of a systemically introduced 30 nm ceria-engineered nanomaterial in ratsToxicol Sci2012127125626822367688
   PubMed Web of Science ®Google Scholar
• YokelRAHussainSGarantziotisSDemokritouPCastranovaVCasseeFRThe yin: an adverse health perspective of nanoceria: uptake, distribution, accumulation, and mechanisms of its toxicityEnviron Sci Nano20141540642825243070
   PubMed Web of Science ®Google Scholar
• KumariMKumariSIGroverPGenotoxicity analysis of cerium oxide micro and nanoparticles in Wistar rats after 28 days of repeated oral administrationMutagenesis201429646747925209125
   PubMed Web of Science ®Google Scholar
• KellerJWohllebenWMa-HockLTime course of lung retention and toxicity of inhaled particles: short-term exposure to nano-ceriaArch Toxicol201488112033205925273020
   PubMed Web of Science ®Google Scholar
• DemokritouPGassSPyrgiotakisGAn in vivo and in vitro toxicological characterisation of realistic nanoscale CeO2 inhalation exposuresNanotoxicology2013781338135023061914
   PubMed Web of Science ®Google Scholar
• JohansonGToxicokinetics and modelingMcQueenCComprehensive Toxicology13rd ed2018165187OxfordElsevier Ltd
   Google Scholar
• IPCSCharacterization and application of physiologically based pharmacokinetic models in risk assessmentIPCS Harmonization Project Document No. 9Geneve, SwitzerlandWorld Health Organization (WHO)2010 Available from: http://www.who.int/ipcs/methods/harmonization/areas/pbpk_models.pdfAccessed March 12, 2018
   Google Scholar
• LinZMonteiro-RiviereNARiviereJEPharmacokinetics of metallic nanoparticlesWiley Interdiscip Rev Nanomed Nanobiotechnol20157218921725316649
   PubMed Web of Science ®Google Scholar
• LiMAl-JamalKTKostarelosKReinekeJPhysiologically based pharmacokinetic modeling of nanoparticlesACS Nano20104116303631720945925
   PubMed Web of Science ®Google Scholar
• SnipesMBLong-term retention and clearance of particles inhaled by mammalian speciesCrit Rev Toxicol19892031752112692607
   PubMed Web of Science ®Google Scholar
• PengBAndrewsJNestorovIBrennanBNicklinPRowlandMTissue distribution and physiologically based pharmacokinetics of antisense phosphorothioate oligonucleotide ISIS 1082 in ratAntisense Nucleic Acid Drug Dev2001111152711258618
   PubMedGoogle Scholar
• LinPChenJWChangLWComputational and ultrastructural toxicology of a nanoparticle, Quantum Dot 705, in miceEnviron Sci Technol200842166264627018767697
   PubMed Web of Science ®Google Scholar
• LeeHALeavensTLMasonSEMonteiro-RiviereNARiviereJEComparison of quantum dot biodistribution with a blood-flow-limited physiologically based pharmacokinetic modelNano Lett20099279479919128005
   PubMed Web of Science ®Google Scholar
• PeryARBrochotCHoetPHNemmarABoisFYDevelopment of a physiologically based kinetic model for 99m-technetium-labelled carbon nanoparticles inhaled by humansInhal Toxicol200921131099110719814607
   PubMed Web of Science ®Google Scholar
• MacCalmanLTranCLKuempelEDevelopment of a bio-mathematical model in rats to describe clearance, retention and translocation of inhaled nano particles throughout the bodyJ Phys Conf Ser20091511012028
   Google Scholar
• LankveldDPOomenAGKrystekPThe kinetics of the tissue distribution of silver nanoparticles of different sizesBiomaterials201031328350836120684985
   PubMed Web of Science ®Google Scholar
• OpitzAWWickstromEThakurMLWagnerNJPhysiologically based pharmacokinetics of molecular imaging nanoparticles for mRNA detection determined in tumor-bearing miceOligonucleotides201020311712520406142
   PubMedGoogle Scholar
• LiMReinekeJMathemathical modelling of nanoparticle biodistribution: extrapolation among intravenous, oral and pulmonary administration routesInt J Nano Biomaterials201133222238
   Google Scholar
• MagerDEModyVXuCPhysiologically based pharmacokinetic model for composite nanodevices: effect of charge and size on in vivo dispositionPharmaceut Res201229925342542
   PubMed Web of Science ®Google Scholar
• LiMPanagiZAvgoustakisKReinekeJPhysiologically based pharmacokinetic modeling of PLGA nanoparticles with varied mPEG contentInt J Nanomedicine201271345135622419876
   PubMed Web of Science ®Google Scholar
• BachlerGvon GoetzNHungerbuhlerKA physiologically based pharmacokinetic model for ionic silver and silver nanoparticlesInt J Nanomedicine201383365338224039420
   PubMed Web of Science ®Google Scholar
• KolanjiyilAVKleinstreuerCNanoparticle mass transfer from lung airways to systemic regions – Part II: multi-compartmental modelingJ Biomech Eng20131351212100424008585
   PubMed Web of Science ®Google Scholar
• KaganLGershkovichPWasanKMMagerDEDual physiologically based pharmacokinetic model of liposomal and nonliposomal amphotericin B dispositionPharm Res2014311354523793994
   PubMed Web of Science ®Google Scholar
• LiDJohansonGEmondCCarlanderUPhilbertMJollietOPhysiologically based pharmacokinetic modeling of polyethylene glycol-coated polyacrylamide nanoparticles in ratsNanotoxicology20148S112813724392664
   PubMedGoogle Scholar
• RajoliRKRBackDJRannardSPhysiologically based pharmacokinetic modelling to inform development of intramuscular long-acting nanoformulations for HIVClin Pharmacokinet201554663965025523214
   PubMed Web of Science ®Google Scholar
• BachlerGvon GoetzNHungerbuhlerKUsing physiologically based pharmacokinetic (PBPK) modeling for dietary risk assessment of titanium dioxide (TiO2) nanoparticlesNanotoxicology20159337338025058655
   PubMed Web of Science ®Google Scholar
• DongDWangXWangHLZhangXWWangYFWuBJElucidating the in vivo fate of nanocrystals using a physiologically based pharmacokinetic model: a case study with the anticancer agent SNX-2112Int J Nanomedicine2015102521253525848269
   PubMed Web of Science ®Google Scholar
• LinZMonteiro-RiviereNARiviereJEA physiologically based phar-macokinetic model for polyethylene glycol-coated gold nanoparticles of different sizes in adult miceNanotoxicology201610216217225961857
   PubMed Web of Science ®Google Scholar
• GilkeyMJKrishnanVScheetzLJiaXRajasekaranAKDhurjatiPSPhysiologically based pharmacokinetic modeling of fluorescently labeled block copolymer nanoparticles for controlled drug delivery in leukemia therapyCPT Pharmacometrics Syst Pharmacol201543e0001326225236
   PubMedGoogle Scholar
• ElgrabliDBeaudouinRJbilouNBiodistribution and clearance of TiO2 nanoparticles in rats after intravenous injectionPLoS One2015104e012449025909957
   PubMed Web of Science ®Google Scholar
• ChenWYChengYHHsiehNHPhysiologically based pharmacokinetic modeling of zinc oxide nanoparticles and zinc nitrate in miceInt J Nanomedicine2015106277629226491297
   PubMed Web of Science ®Google Scholar
• BachlerGLosertSUmeharaYTranslocation of gold nanoparticles across the lung epithelial tissue barrier: combining in vitro and in silico methods to substitute in vivo experimentsPart Fibre Toxicol20151211826116549
   PubMedGoogle Scholar
• SweeneyLMMacCalmanLHaberLTKuempelEDTranCLBayesian evaluation of a physiologically-based pharmacokinetic (PBPK) model of long-term kinetics of metal nanoparticles in ratsRegul Toxicol Pharmacol201573115116326145831
   PubMed Web of Science ®Google Scholar
• LinZMonteiro-RiviereNAKannanRRiviereJEA computational framework for interspecies pharmacokinetics, exposure and toxicity assessment of gold nanoparticlesNanomedicine201611210711926653715
   PubMed Web of Science ®Google Scholar
• LiDMorishitaMWagnerJGIn vivo biodistribution and physiologically based pharmacokinetic modeling of inhaled fresh and aged cerium oxide nanoparticles in ratsPart Fibre Toxicol20161314527542346
   PubMedGoogle Scholar
• LaomettachitTPuriIKLiangruksaMA two-step model of TiO2 nanoparticle toxicity in human liver tissueToxicol Appl Pharm20173344754
   PubMed Web of Science ®Google Scholar
• LinZJaberi-DourakiMHeCPerformance assessment and translation of physiologically based pharmacokinetic models from acslX to Berkeley Madonna, MATLAB, and R Language: Oxytetracycline and gold nanoparticles as case examplesToxicol Sci20171581233528402537
   PubMed Web of Science ®Google Scholar
• CarlanderULiDJollietOEmondCJohansonGToward a general physiologically-based pharmacokinetic model for intravenously injected nanoparticlesInt J Nanomedicine20161162564026929620
   PubMed Web of Science ®Google Scholar
• KonduruNVJimenezRJSwamiASilica coating influences the corona and biokinetics of cerium oxide nanoparticlesPart Fibre Toxicol2015123126458946
   PubMed Web of Science ®Google Scholar
• UtembeWPotgieterKStefaniakABGulumianMDissolution and biodurability: Important parameters needed for risk assessment of nanomaterialsPart Fibre Toxicol2015121125927337
   PubMed Web of Science ®Google Scholar
• DecuzziPGodinBTanakaTSize and shape effects in the biodistribution of intravascularly injected particlesJ Control Release2010141332032719874859
   PubMed Web of Science ®Google Scholar
• KeeneAMPetersDRouseRStewartSRosenETTynerKMTissue and cellular distribution of gold nanoparticles varies based on aggregation/agglomeration statusNanomedicine20127219920922339133
   PubMed Web of Science ®Google Scholar
• TenzerSDocterDKuharevJRapid formation of plasma protein corona critically affects nanoparticle pathophysiologyNat Nanotechnol201381077278124056901
   PubMed Web of Science ®Google Scholar
• OwensDE3rdPeppasNAOpsonization, biodistribution, and pharmacokinetics of polymeric nanoparticlesInt J Pharmaceut2006307193102
   PubMed Web of Science ®Google Scholar
• CantonIBattagliaGEndocytosis at the nanoscaleChem Soc Rev20124172718273922389111
   PubMed Web of Science ®Google Scholar
• YokelRATsengMTDanMBiodistribution and biopersistence of ceria engineered nanomaterials: size dependenceNanomedicine20139339840722960425
   PubMed Web of Science ®Google Scholar
• YokelRAUnrineJMWuPWangBHGrulkeEANanoceria biodistribution and retention in the rat after its intravenous administration are not greatly influenced by dosing schedule, dose, or particle shapeEnviron Sci Nano201416549560
   Web of Science ®Google Scholar
• HeckmanKLDeCoteauWEstevezACustom cerium oxide nanoparticles protect against a free radical mediated autoimmune degenerative disease in the brainACS Nano2013712105821059624266731
   PubMed Web of Science ®Google Scholar
• HardasSSButterfieldDASultanaRBrain distribution and toxicological evaluation of a systemically delivered engineered nanoscale ceriaToxicol Sci2010116256257620457660
   PubMed Web of Science ®Google Scholar
• KonduruNVJimenezRJSwamiAErratum to: Silica coating influences the corona and biokinetics of cerium oxide nanoparticles (vol 12, 31, 2015)Part Fibre Toxicol2016133527334863
   PubMed Web of Science ®Google Scholar
• DanMWuPGrulkeEAGrahamUMUnrineJMYokelRACeria-engineered nanomaterial distribution in, and clearance from, blood: size mattersNanomedicine (Lond)2012719511022191779
   PubMed Web of Science ®Google Scholar
• YokelRAFlorenceRLUnrineJMBiodistribution and oxidative stress effects of a systemically-introduced commercial ceria engineered nanomaterialNanotoxicology200933234248
   Web of Science ®Google Scholar
• HeXZhangHMaYLung deposition and extrapulmonary translocation of nano-ceria after intratracheal instillationNanotechnology2010212828510320562477
   PubMed Web of Science ®Google Scholar
• NalabotuSKKolliMBTriestWEIntratracheal instillation of cerium oxide nanoparticles induces hepatic toxicity in male Sprague-Dawley ratsInt J Nanomedicine201162327233522072870
   PubMed Web of Science ®Google Scholar
• ParkEJParkYKParkKAcute toxicity and tissue distribution of cerium oxide nanoparticles by a single oral administration in ratsToxicol Res20092527984
   PubMedGoogle Scholar
• KumariMKumariSIKamalSSKGroverPGenotoxicity assessment of cerium oxide nanoparticles in female Wistar rats after acute oral exposureMutat Res Genet Toxicol Environ Mutagen201477571925435351
   PubMed Web of Science ®Google Scholar
• GrahamUMTsengMTJasinskiJBIn vivo processing of ceria nanoparticles inside liver: impact on free-radical scavenging activity and oxidative stressChempluschem20147981083108826322251
   PubMed Web of Science ®Google Scholar
• HirstSMKarakotiASinghSBio-distribution and in vivo antioxidant effects of cerium oxide nanoparticles in miceEnviron Toxicol201328210711821618676
   PubMed Web of Science ®Google Scholar
• PortioliCBenatiDPilYShort-term biodistribution of cerium oxide nanoparticles in mice: Focus on brain parenchymaNanosci Nanotechnol Lett201351111741181
   Google Scholar
• AalapatiSGanapathySManapuramSAnumoluGPrakyaBMToxicity and bio-accumulation of inhaled cerium oxide nanoparticles in CD1 miceNanotoxicology20148778679823914771
   PubMed Web of Science ®Google Scholar
• CestaMFNormal structure, function, and histology of the spleenToxicol Pathol200634545546517067939
   PubMed Web of Science ®Google Scholar
• Van FurthRDiesselhoff-den DulkMMCharacterization of mononuclear phagocytes from the mouse, guinea pig, rat, and manInflammation19826139536282747
   PubMed Web of Science ®Google Scholar
• HaleyPJSpecies differences in the structure and function of the immune systemToxicology20031881497112748041
   PubMed Web of Science ®Google Scholar
• ChithraniBDGhazaniAAChanWCDetermining the size and shape dependence of gold nanoparticle uptake into mammalian cellsNano Lett20066466266816608261
   PubMed Web of Science ®Google Scholar
• ZhangSLiJLykotrafitisGBaoGSureshSSize-dependent endocytosis of nanoparticlesAdv Mater20092141942419606281
   PubMed Web of Science ®Google Scholar
• DasguptaSAuthTGompperGShape and orientation matter for the cellular uptake of nonspherical particlesNano Lett201414268769324383757
   PubMed Web of Science ®Google Scholar
• DocterDWestmeierDMarkiewiczMStolteSKnauerSKStauberRHThe nanoparticle biomolecule corona: lessons learned – challenge accepted?Chem Soc Rev201544176094612126065524
   PubMed Web of Science ®Google Scholar
• MuQXJiangGBChenLXChemical basis of interactions between engineered nanoparticles and biological systemsChem Rev2014114157740778124927254
   PubMed Web of Science ®Google Scholar
• YokelRAPhysicochemical properties of engineered nanomaterials that influence their nervous system distribution and effectsNanomed Nanotechnol201612720812093
   PubMed Web of Science ®Google Scholar
• GrahamUMYokelRADozierAKAnalytical high-resolution electron microscopy reveals organ-specific nanoceria bioprocessingToxicol Pathol2017461476129145781
   PubMed Web of Science ®Google Scholar
• Semmler-BehnkeMKreylingWGLipkaJBiodistribution of 1.4- and 18-nm gold particles in ratsSmall20084122108211119031432
   PubMed Web of Science ®Google Scholar
• KreylingWGHirnSMollerWAir-blood barrier translocation of tracheally instilled gold nanoparticles inversely depends on particle sizeACS Nano20148122223324364563
   PubMed Web of Science ®Google Scholar
• BrownRPDelpMDLindstedtSLRhombergLRBelilesRPPhysiological parameter values for physiologically based pharmacokinetic modelsToxicol Ind Health19971344074849249929
   PubMed Web of Science ®Google Scholar
• DaviesBMorrisTPhysiological parameters in laboratory animals and humansPharm Res1993107109310958378254
   PubMed Web of Science ®Google Scholar
• TreuelLBrandholtSMaffrePWiegeleSShangLNienhausGUImpact of protein modification on the protein corona on nanoparticles and nanoparticle-cell interactionsACS Nano20148150351324377255
   PubMed Web of Science ®Google Scholar
• CohenJMDeLoidGMDemokritouPA critical review of in vitro dosimetry for engineered nanomaterialsNanomedicine (Lond)201510193015303226419834
   PubMed Web of Science ®Google Scholar
• SalvatiAAbergCdos SantosTExperimental and theoretical comparison of intracellular import of polymeric nanoparticles and small molecules: toward models of uptake kineticsNanomedicine20117681882621453790
   PubMed Web of Science ®Google Scholar
• YoonMCampbellJLAndersenMEClewellHJQuantitative in vitro to in vivo extrapolation of cell-based toxicity assay resultsCrit Rev Toxicol201242863365222667820
   PubMed Web of Science ®Google Scholar
• WohllebenWDriessenMDRaeschSInfluence of agglomeration and specific lung lining lipid/protein interaction on short-term inhalation toxicityNanotoxicology201610797098026984182
   PubMed Web of Science ®Google Scholar
• WalczakAPFokkinkRPetersRBehaviour of silver nanoparticles and silver ions in an in vitro human gastrointestinal digestion modelNanotoxicology2013771198121022931191
   PubMed Web of Science ®Google Scholar
• MarquesMRCLoebenbergRAlmukainziMSimulated biological fluids with possible application in dissolution testingDissolution Technol20111831528
   Web of Science ®Google Scholar
• BruininkAWangJWickPEffect of particle agglomeration in nanotoxicologyArch Toxicol201589565967525618546
   PubMed Web of Science ®Google Scholar
• ZhangWNanoparticle aggregation: principles and modelingAdv Exp Med Biol2014811194324683025
   PubMed Web of Science ®Google Scholar
• WalkeyCDOlsenJBSongFProtein corona fingerprinting predicts the cellular interaction of gold and silver nanoparticlesACS Nano2014832439245524517450
   PubMed Web of Science ®Google Scholar
• ChoiHSAshitateYLeeJHRapid translocation of nanoparticles from the lung airspaces to the bodyNat Biotechnol201028121300130321057497
   PubMed Web of Science ®Google Scholar
• TobioMSanchezAVilaAThe role of PEG on the stability in digestive fluids and in vivo fate of PEG-PLA nanoparticles following oral administrationColloids Surf B Biointerfaces2000183–431532310915953
   PubMed Web of Science ®Google Scholar