106
Views
17
CrossRef citations to date
0
Altmetric
Original Research

Dual-drug nanomedicine with hydrophilic F127-modified magnetic nanocarriers assembled in amphiphilic gelatin for enhanced penetration and drug delivery in deep tumor tissue

, , &
Pages 3011-3026 | Published online: 22 May 2018

References

  • DuncanRPolymer conjugates as anticancer nanomedicinesNat Rev Cancer20066968870116900224
  • PeerDKarpJMHongSFarokhzadOCMargalitRLangerRNanocarriers as an emerging platform for cancer therapyNat Nano2007212751760
  • ChauhanVPStylianopoulosTBoucherYJainRKDelivery of molecular and nanoscale medicine to tumors: transport barriers and strategiesAnnu Rev Chem Biomol Eng2011228129822432620
  • ShiJVotrubaARFarokhzadOCLangerRNanotechnology in drug delivery and tissue engineering: from discovery to applicationsNano Lett20101093223323020726522
  • NicholsJWBaeYHOdyssey of a cancer nanoparticle: from injection site to site of actionNano Today20127660661823243460
  • WaiteCLRothCMNanoscale drug delivery systems for enhanced drug penetration into solid tumors: current progress and opportunitiesCrit Rev Biomed Eng2012401214122428797
  • JainRKStylianopoulosTDelivering nanomedicine to solid tumorsNat Rev Clin Oncol201071165366420838415
  • LongmireMChoykePLKobayashiHClearance properties of nanosized particles and molecules as imaging agents: considerations and caveatsNanomedicine (Lond)20083570371718817471
  • BaruaSMitragotriSChallenges associated with penetration of nanoparticles across cell and tissue barriers: a review of current status and future prospectsNano Today20149222324325132862
  • GoodmanTTOlivePLPunSHIncreased nanoparticle penetration in collagenase-treated multicellular spheroidsInt J Nanomedicine20072226527417722554
  • WongCStylianopoulosTCuiJMultistage nanoparticle delivery system for deep penetration into tumor tissueProc Natl Acad Sci U S A201110862426243121245339
  • JuCMoRXueJSequential intra-intercellular nanoparticle delivery system for deep tumor penetrationAngew Chem Int Ed2014532462536258
  • KhawarIAKimJHKuhHJImproving drug delivery to solid tumors: priming the tumor microenvironmentJ Control Release2015201788925526702
  • ZhangBShiWJiangTOptimization of the tumor microenvironment and nanomedicine properties simultaneously to improve tumor therapyOncotarget2016738626076261827566585
  • LaiC-YFiteBZFerraraKWUltrasonic enhancement of drug penetration in solid tumorsFront Oncol2013320423967400
  • SuYLFangJHLiaoCYLinCTLiYTHuSHTargeted mesoporous iron oxide nanoparticles-encapsulated perfluorohexane and a hydrophobic drug for deep tumor penetration and therapyTheranostics20155111233124826379789
  • NieSUnderstanding and overcoming major barriers in cancer nanomedicineNanomedicine (Lond)20105452352820528447
  • MinchintonAITannockIFDrug penetration in solid tumoursNat Rev Cancer20066858359216862189
  • KwonIKLeeSCHanBParkKAnalysis on the current status of targeted drug delivery to tumorsJ Control Release2012164210811422800574
  • ToroseanSFlynnBAxelssonJNanoparticle uptake in tumors is mediated by the interplay of vascular and collagendensity with interstitial pressureNanomedicine20139215115822841910
  • ChauhanVPMartinJDLiuHAngiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vesselsNat Commun20134251624084631
  • LuPTakaiKWeaverVMWerbZExtracellular matrix degradation and remodeling in development and diseaseCold Spring Harb Perspect Biol2011312a00505821917992
  • LiJZengHCHollowing Sn-doped TiO2 nanospheres via ostwald ripeningJ Am Chem Soc200712951158391584718047331
  • LouXWArcherLAYangZHollow Micro-/nanostructures: synthesis and applicationsAdv Mater2008202139874019
  • PengSSunSSynthesis and characterization of monodisperse hollow Fe3O4 nanoparticlesAngew Chem Int Ed Engl200746224155415817469084
  • NettiPABerkDASwartzMAGrodzinskyAJJainRKRole of extracellular matrix assembly in interstitial transport in solid tumorsCancer Res20006092497250310811131
  • RamanujanSPluenAMcKeeTDBrownEBBoucherYJainRKDiffusion and convection in collagen gels: implications for transport in the tumor interstitiumBiophys J20028331650166012202388
  • AmijiMMPolymeric Gene Delivery: Principles and ApplicationsUSACRC Press2004
  • SuY-LChenK-TSheuY-CThe penetrated delivery of drug and energy to tumors by lipo-graphene nanosponges for photolytic therapyACS Nano2016101094209433