RNA interference: new mechanistic and biochemical insights with application in oral cancer therapy

References

• D’SouzaGMcNeelTSFakhryCUnderstanding personal risk of oropharyngeal cancer: risk-groups for oncogenic oral HPV infection and oropharyngeal cancerAnn Oncol201728123065306929059337
   PubMed Web of Science ®Google Scholar
• WarnakulasuriyaSGlobal epidemiology of oral and oropharyngeal cancerOral Oncol2009454–530931618804401
   PubMed Web of Science ®Google Scholar
• FerlayJSoerjomataramIDikshitRCancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012Int J Cancer20151365E359E38625220842
   PubMed Web of Science ®Google Scholar
• PettiSLifestyle risk factors for oral cancerOral Oncol2009454–534035018674956
   PubMed Web of Science ®Google Scholar
• IrimieAIBraicuCCojocneanu-PetricRBerindan-NeagoeICampianRSNovel technologies for oral squamous carcinoma biomarkers in diagnostics and prognosticsActa Odontol Scand201573316116825598447
   PubMed Web of Science ®Google Scholar
• PileczkiVBraicuCGhermanCDBerindan-NeagoeITNF-alpha gene knockout in triple negative breast cancer cell line induces apoptosisInt J Mol Sci201214141142023263670
   PubMed Web of Science ®Google Scholar
• WangKCChangHYMolecular mechanisms of long noncoding RNAsMol Cell201143690491421925379
   PubMed Web of Science ®Google Scholar
• SetoyamaTLingHNatsugoeSCalinGANon-coding RNAs for medical practice in oncologyKeio J Med201160410611322200634
   PubMedGoogle Scholar
• Berindan-NeagoeICalinGAMolecular pathways: microRNAs, cancer cells, and microenvironmentClin Cancer Res201420246247625325512634
   PubMed Web of Science ®Google Scholar
• Berindan-NeagoeIMonroig PdelCPasculliBCalinGAMicroRNAome genome: a treasure for cancer diagnosis and therapyCA Cancer J Clin201464531133625104502
   PubMed Web of Science ®Google Scholar
• AlexanderRPFangGRozowskyJSnyderMGersteinMBAnnotating non-coding regions of the genomeNat Rev Genet201011855957120628352
   PubMed Web of Science ®Google Scholar
• FrancastelCHubéFManiSSantulliGTaubeJSzweykowska-KulinskaZThe non-coding RNA journal club: highlights on recent papers – 2Noncoding RNA201512167
   Google Scholar
• CalinGVazquezFWelcome to the new journal Non-Coding RNA!Noncoding RNA20151113
   Google Scholar
• LingHVincentKPichlerMJunk DNA and the long non-coding RNA twist in cancer geneticsOncogene201534395003501125619839
   PubMed Web of Science ®Google Scholar
• ZaharieFMuresanMSPetrushevBExosome-carried microRNA-375 inhibits cell progression and dissemination via Bcl-2 blocking in colon cancerJ Gastrointestin Liver Dis201524443544326697569
   PubMed Web of Science ®Google Scholar
• FerracinMGautheretDHubéFThe non-coding RNA journal club: highlights on recent papersNoncoding RNA20151187
   Google Scholar
• AmaralPPMattickJSNoncoding RNA in developmentMamm Genome2008197–845449218839252
   PubMed Web of Science ®Google Scholar
• MunkerRCalinGAMicroRNA profiling in cancerClin Sci (Lond)2011121414115821526983
   PubMed Web of Science ®Google Scholar
• CatanaCSPichlerMGiannelliGMaderRMBerindan-NeagoeINon-coding RNAs, the Trojan horse in two-way communication between tumor and stroma in colorectal and hepatocellular carcinomaOncotarget2017817295192953428392501
   PubMedGoogle Scholar
• BraicuCCatanaCCalinGABerindan-NeagoeINCRNA combined therapy as future treatment option for cancerCurr Pharm Des201420426565657425341933
   PubMed Web of Science ®Google Scholar
• Pop-BicaCGuleiDCojocneanu-PetricRBraicuCPetrutBBerindan-NeagoeIUnderstanding the role of non-coding RNAs in bladder cancer: from dark matter to valuable therapeutic targetsInt J Mol Sci2017187E151428703782
   PubMed Web of Science ®Google Scholar
• BraicuCCojocneanu-PetricRChiraSClinical and pathological implications of miRNA in bladder cancerInt J Nanomedicine20151079180025653521
   PubMed Web of Science ®Google Scholar
• IrimieAIBraicuCSoneaLA looking-glass of non-coding RNAs in oral cancerInt J Mol Sci20171812E262029206174
   PubMed Web of Science ®Google Scholar
• HamiltonAJBaulcombeDCA species of small antisense RNA in posttranscriptional gene silencing in plantsScience1999286544195095210542148
   PubMed Web of Science ®Google Scholar
• CarthewRWSontheimerEJOrigins and mechanisms of miRNAs and siRNAsCell2009136464265519239886
   PubMed Web of Science ®Google Scholar
• DanaHChalbataniGMMahmoodzadehHMolecular mechanisms and biological functions of siRNAInt J Biomed Sci2017132485728824341
   PubMedGoogle Scholar
• LamJKChowMYZhangYLeungSWsiRNA versus miRNA as therapeutics for gene silencingMol Ther Nucleic Acids20154e25226372022
   PubMedGoogle Scholar
• Alexander-BryantAAZhangHAttawayCCDual peptide-mediated targeted delivery of bioactive siRNAs to oral cancer cells in vivoOral Oncol20177212313128797448
   PubMed Web of Science ®Google Scholar
• FakhrEZareFTeimoori-ToolabiLPrecise and efficient siRNA design: a key point in competent gene silencingCancer Gene Ther2016234738226987292
   PubMed Web of Science ®Google Scholar
• TilesiFFradianiPSocciVWillemsDAscenzioniFDesign and validation of siRNAs and shRNAsCurr Opin Mol Ther200911215616419330721
   PubMedGoogle Scholar
• TaferHBioinformatics of siRNA designMethods Mol Biol2014109747749024639173
   PubMedGoogle Scholar
• HickersonRPVlassovAVWangQStability study of unmodified siRNA and relevance to clinical useOligonucleotides200818434535418844576
   PubMedGoogle Scholar
• ChernolovskayaELZenkovaMAChemical modification of siRNACurr Opin Mol Ther201012215816720373259
   PubMedGoogle Scholar
• ChoiHSLiuWMisraPRenal clearance of nanoparticlesNat Biotechnol200725101165117017891134
   PubMed Web of Science ®Google Scholar
• MieleESpinelliGPMieleENanoparticle-based delivery of small interfering RNA: challenges for cancer therapyInt J Nanomedicine201273637365722915840
   PubMed Web of Science ®Google Scholar
• IrimieAISoneaLJurjAFuture trends and emerging issues for nanodelivery systems in oral and oropharyngeal cancerInt J Nanomedicine2017124593460628721037
   PubMed Web of Science ®Google Scholar
• GavrilovKSaltzmanWMTherapeutic siRNA: principles, challenges, and strategiesYale J Biol Med201285218720022737048
   PubMedGoogle Scholar
• JacksonALLinsleyPSRecognizing and avoiding siRNA off-target effects for target identification and therapeutic applicationNat Rev Drug Discov201091576720043028
   PubMed Web of Science ®Google Scholar
• MengZLuMRNA interference-induced innate immunity, off-target effect, or immune adjuvant?Front Immunol2017833128386261
   PubMed Web of Science ®Google Scholar
• DominskaMDykxhoornDMBreaking down the barriers: siRNA delivery and endosome escapeJ Cell Sci2010123Pt 81183118920356929
   PubMed Web of Science ®Google Scholar
• DalbyBCatesSHarrisAAdvanced transfection with Lipofectamine 2000 reagent: primary neurons, siRNA, and high-throughput applicationsMethods20043329510315121163
   PubMed Web of Science ®Google Scholar
• CantiniLAttawayCCButlerBAndinoLMSokoloskyMLJakymiwAFusogenic-oligoarginine peptide-mediated delivery of siRNAs targeting the CIP2A oncogene into oral cancer cellsPLoS One201389e7334824019920
   PubMed Web of Science ®Google Scholar
• ChalkAMWarfingeREGeorgii-HemmingPSonnhammerELLsiRNAdb: a database of siRNA sequencesNucleic Acids Res200533Database issueD131D13415608162
   PubMedGoogle Scholar
• GongWRenYZhouHWangYKangSLiTsiDRM: an effective and generally applicable online siRNA design toolBioinformatics200824202405240618718944
   PubMed Web of Science ®Google Scholar
• JiangPWuHDaYRFRCDB-siRNA: improved design of siRNAs by random forest regression model coupled with database searchingComput Methods Programs Biomed200787323023817644215
   PubMed Web of Science ®Google Scholar
• RNAcentral ConsortiumRNAcentral: an international database of ncRNA sequencesNucleic Acids Res201543Database issueD123D12925352543
   PubMedGoogle Scholar
• OckerMNeureiterDLuedersMVariants of bcl-2 specific siRNA for silencing antiapoptotic bcl-2 in pancreatic cancerGut20055491298130816099798
   PubMed Web of Science ®Google Scholar
• TatipartiKSauSKashawSKIyerAKsiRNA delivery strategies: a comprehensive review of recent developmentsNanomaterials (Basel)201774E7728379201
   PubMedGoogle Scholar
• HanLTangCYinCOral delivery of shRNA and siRNA via multifunctional polymeric nanoparticles for synergistic cancer therapyBiomaterials201435154589460024613049
   PubMed Web of Science ®Google Scholar
• OliveiraSStormGSchiffelersRMTargeted delivery of siRNAJ Biomed Biotechnol2006200646367517057365
   PubMedGoogle Scholar
• XuDMcCartyDFernandesAFisherMSamulskiRJJulianoRLDelivery of MDR1 small interfering RNA by self-complementary recombinant adeno-associated virus vectorMol Ther200511452353015771955
   PubMed Web of Science ®Google Scholar
• AkhtarSBenterIFNonviral delivery of synthetic siRNAs in vivoJ Clin Invest2007117123623363218060020
   PubMed Web of Science ®Google Scholar
• LiSDHuangLGene therapy progress and prospects: non-viral gene therapy by systemic deliveryGene Ther200613181313131916953249
   PubMed Web of Science ®Google Scholar
• BiswasSTorchilinVPDendrimers for siRNA deliveryPharmaceuticals (Basel)20136216118324275946
   PubMedGoogle Scholar
• WangBKYuXFWangJHGold-nanorods-siRNA nanoplex for improved photothermal therapy by gene silencingBiomaterials201678273926646625
   PubMed Web of Science ®Google Scholar
• NeagoeIBBraicuCMateaCEfficient siRNA delivery system using carboxilated single-wall carbon nanotubes in cancer treatmentJ Biomed Nanotechnol20128456757422852466
   PubMed Web of Science ®Google Scholar
• GhermanCTudorMCConstantinBPharmacokinetics evaluation of carbon nanotubes using FTIR analysis and histological analysisJ Nanosci Nanotechnol20151542865286926353506
   PubMed Web of Science ®Google Scholar
• LeeJBHongJBonnerDKPoonZHammondPTSelf-assembled RNA interference microsponges for efficient siRNA deliveryNat Mater201211431632222367004
   PubMed Web of Science ®Google Scholar
• YangQLaiSKAnti-PEG immunity: emergence, characteristics, and unaddressed questionsWiley Interdiscip Rev Nanomed Nanobiotechnol20157565567725707913
   PubMed Web of Science ®Google Scholar
• JudgeAMacLachlanIOvercoming the innate immune response to small interfering RNAHuman Gene Ther200819211112418230025
   PubMed Web of Science ®Google Scholar
• RobbinsMJudgeAMacLachlanIsiRNA and innate immunityOligonucleotides20091928910219441890
   PubMed Web of Science ®Google Scholar
• ChernikovIVGladkikhDVMeschaninovaMICholesterol-containing nuclease-resistant siRNA accumulates in tumors in a carrier-free mode and silences MDR1 geneMol Ther Nucleic Acids2017620922028325287
   PubMedGoogle Scholar
• GourroncFARockeyWMThielWHGiangrandePHKlingelhutzAJIdentification of RNA aptamers that internalize into HPV-16 E6/E7 transformed tonsillar epithelial cellsVirology20134461–232533324074596
   PubMed Web of Science ®Google Scholar
• ButzKRistrianiTHengstermannADenkCScheffnerMHoppe-SeylerFsiRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cellsOncogene200322385938594512955072
   PubMed Web of Science ®Google Scholar
• WangJLuZWientjesMGAuJLDelivery of siRNA therapeutics: barriers and carriersAAPS J201012449250320544328
   PubMed Web of Science ®Google Scholar
• LiuXHuangHWangJDendrimers-delivered short hairpin RNA targeting hTERT inhibits oral cancer cell growth in vitro and in vivoBiochem Pharmacol2011821172321453684
   PubMed Web of Science ®Google Scholar
• YuTWuYHuangYRNAi targeting CXCR4 inhibits tumor growth through inducing cell cycle arrest and apoptosisMol Ther201220239840722108861
   PubMed Web of Science ®Google Scholar
• XuLYeudallWAYangHFolic acid-decorated polyamidoamine dendrimer exhibits high tumor uptake and sustained highly localized retention in solid tumors: its utility for local siRNA deliveryActa Biomater20175725126128438704
   PubMed Web of Science ®Google Scholar
• WangDXuXZhangKCodelivery of doxorubicin and MDR1-siRNA by mesoporous silica nanoparticles-polymerpolyethylenimine to improve oral squamous carcinoma treatmentInt J Nanomedicine20181318719829343957
   PubMed Web of Science ®Google Scholar
• BraicuCPileczkiVIrimieABerindan-NeagoeIp53siRNA therapy reduces cell proliferation, migration and induces apoptosis in triple negative breast cancer cellsMol Cell Biochem20133811–2616823881244
   PubMed Web of Science ®Google Scholar
• AldeaMCraciunLTomuleasaCRepositioning metformin in cancer: genetics, drug targets, and new ways of deliveryTumour Biol20143565101511024504677
   PubMedGoogle Scholar
• AldeaMDPetrushevBSoritauOMetformin plus sorafenib highly impacts temozolomide resistant glioblastoma stem-like cellsJ BUON201419250251124965413
   PubMed Web of Science ®Google Scholar
• RoperoSEstellerMThe role of histone deacetylases (HDACs) in human cancerMol Oncol200711192519383284
   PubMed Web of Science ®Google Scholar
• AhnMYYoonJHHistone deacetylase 8 as a novel therapeutic target in oral squamous cell carcinomaOncol Rep201737154054628004115
   PubMed Web of Science ®Google Scholar
• ZhengXJiaBLinXFRMD4A: a potential therapeutic target for the treatment of tongue squamous cell carcinomaInt J Mol Med20163851443144927666346
   PubMed Web of Science ®Google Scholar
• Ramezani-RadPGengHHurtzCSOX4 enables oncogenic survival signals in acute lymphoblastic leukemiaBlood2013121114815523152540
   PubMed Web of Science ®Google Scholar
• LiuYCuiLHuangJSOX4 promotes progression in OLP-associated squamous cell carcinomaJ Cancer20167111534154027471569
   PubMed Web of Science ®Google Scholar
• GeorgakopoulouEATroupisTGTroupisGGorgoulisVGUpdate of the cancer-associated molecular mechanisms in oral lichen planus, a disease with possible premalignant natureJ Buon201116461361622331711
   PubMed Web of Science ®Google Scholar
• IrimieAIBraicuCPileczkiVKnocking down of p53 triggers apoptosis and autophagy, concomitantly with inhibition of migration on SSC-4 oral squamous carcinoma cellsMol Cell Biochem20164191–2758227370646
   PubMed Web of Science ®Google Scholar
• WinckFVPrado RibeiroACRamos DominguesRInsights into immune responses in oral cancer through proteomic analysis of saliva and salivary extracellular vesiclesSci Rep201551630526538482
   PubMed Web of Science ®Google Scholar
• ChanLPWangLFChiangFYLeeKWKuoPLLiangCHIL-8 promotes HNSCC progression on CXCR1/2-mediated NOD1/RIP2 signaling pathwayOncotarget2016738618206183127557518
   PubMedGoogle Scholar
• PunyaniSRSathawaneRSSalivary level of interleukin-8 in oral precancer and oral squamous cell carcinomaClin Oral Investig2013172517524
   PubMed Web of Science ®Google Scholar
• DuanYZhangSWangLTargeted silencing of CXCR4 inhibits epithelial–mesenchymal transition in oral squamous cell carcinomaOncol Lett20161232055206127602138
   PubMed Web of Science ®Google Scholar
• GaoXLWuJSCaoMXCytokeratin-14 contributes to collective invasion of salivary adenoid cystic carcinomaPLoS One2017122e017134128152077
   PubMed Web of Science ®Google Scholar
• ZhangZTaoDZhangPHyaluronan synthase 2 expressed by cancer-associated fibroblasts promotes oral cancer invasionJ Exp Clin Cancer Res201635118127884164
   PubMedGoogle Scholar
• PatilSRaoRSGanaviBSMesenchymal–epithelial transition in oral cancerJ Int Oral Health201579iii
   Google Scholar
• HinoMKamoMSaitoDTransforming growth factor-beta1 induces invasion ability of HSC-4 human oral squamous cell carcinoma cells through the Slug/Wnt-5b/MMP-10 signalling axisJ Biochem2016159663164026861993
   PubMed Web of Science ®Google Scholar
• PiaoSInglehartRCScanlonCSRussoNBanerjeeRD’SilvaNJCDH11 inhibits proliferation and invasion in head and neck cancerJ Oral Pathol Med2017462899727397103
   PubMed Web of Science ®Google Scholar
• HuangZXieJLinSThe downregulation of ANGPTL4 inhibits the migration and proliferation of tongue squamous cell carcinomaArch Oral Biol20167114414927505034
   PubMed Web of Science ®Google Scholar
• LiCLiQCaiYOverexpression of angiopoietin 2 promotes the formation of oral squamous cell carcinoma by increasing epithelial–mesenchymal transition-induced angiogenesisCancer Gene Ther201623929530227492854
   PubMed Web of Science ®Google Scholar
• ChangBYangHJiaoYSOD2 deregulation enhances migration, invasion and has poor prognosis in salivary adenoid cystic carcinomaSci Rep201662591827181103
   PubMed Web of Science ®Google Scholar
• MkHPrinceSMohanAMKrishnanKVDeviAAssociation of Notch4 with metastasis in human oral squamous cell carcinomaLife Sci2016156384627197026
   PubMed Web of Science ®Google Scholar
• FengXJiangYXieLOverexpression of proteasomal activator PA28α serves as a prognostic factor in oral squamous cell carcinomaJ Exp Clin Cancer Res2016353526892607
   PubMed Web of Science ®Google Scholar
• SakakuraKTakahashiHKairaKRelationship between tumor-associated macrophage subsets and CD47 expression in squamous cell carcinoma of the head and neck in the tumor microenvironmentLab Invest2016969994100327322955
   PubMed Web of Science ®Google Scholar
• WeiTCongXWangXTInterleukin-17A promotes tongue squamous cell carcinoma metastasis through activating miR-23b/versican pathwayOncotarget2017846663668028035060
   PubMedGoogle Scholar
• YangWEHoCCYangSFCathepsin B expression and the correlation with clinical aspects of oral squamous cell carcinomaPLoS One2016113e015216527031837
   PubMed Web of Science ®Google Scholar
• MaCShiLHuangYNanoparticle delivery of Wnt-1 siRNA enhances photodynamic therapy by inhibiting epithelial–mesenchymal transition for oral cancerBiomater Sci20175349450128070573
   PubMed Web of Science ®Google Scholar
• AliMRAliHRRankinCREl-SayedMATargeting heat shock protein 70 using gold nanorods enhances cancer cell apoptosis in low dose plasmonic photothermal therapyBiomaterials20161021827318931
   PubMed Web of Science ®Google Scholar
• JiangLZengXWangZChenQCell line cross-contamination: KB is not an oral squamous cell carcinoma cell lineEur J Oral Sci20091171909119196324
   PubMed Web of Science ®Google Scholar
• GhahhariNMBabashahSInterplay between microRNAs and WNT/β-catenin signalling pathway regulates epithelial-mesenchymal transition in cancerEur J Cancer201551121638164926025765
   PubMed Web of Science ®Google Scholar
• LecarosRLHuangLLeeTCHsuYCNanoparticle delivered VEGF-A siRNA enhances photodynamic therapy for head and neck cancer treatmentMol Ther201624110611626373346
   PubMed Web of Science ®Google Scholar
• ChenWHLecarosRLTsengYCHuangLHsuYCNanoparticle delivery of HIF1α siRNA combined with photodynamic therapy as a potential treatment strategy for head-and-neck cancerCancer Lett20153591657425596376
   PubMed Web of Science ®Google Scholar
• TolcherAWHaoDde BonoJPhase I, pharmacokinetic, and pharmacodynamic study of intravenously administered Ad5CMV-p53, an adenoviral vector containing the wild-type p53 gene, in patients with advanced cancerJ Clin Oncol200624132052205816648505
   PubMed Web of Science ®Google Scholar
• INGN 201: Ad-p53, Ad5CMV-p53, adenoviral p53, p53 gene therapy-introgen, RPR/INGN 201Drugs R D20078317618717472413
   PubMedGoogle Scholar
• M.D. Anderson Cancer CenterAdenovirus for Oral Premalignancies Available from: https://clinicaltrials.gov/ct2/show/NCT00410865?term=p53&cond=oral+cancer&draw=1&rank=2. NLM identifier: NCT00410865Accessed January 10, 2018
   Google Scholar
• National Cancer Institute (NCI)Gene Therapy in Preventing Cancer in Patients With Premalignant Carcinoma of the Oral Cavity or Pharynx Available from: https://clinicaltrials.gov/ct2/show/study/NCT00064103?term=p53&cond=oral+cancer&draw=1&rank=3. NLM identifier: NCT00064103Accessed January 10, 2018
   Google Scholar
• Shenzhen SiBiono GeneTech Co., LtdrAd-p53 Gene Therapy for Advanced Oral and Maxillofacial Malignant Tumors (rAd-p53) Available from: https://clinicaltrials.gov/ct2/show/study/NCT00902083?term=p53&cond=oral+cancer&draw=1&rank=6. NLM identifier: NCT00902083Accessed January 10, 2018
   Google Scholar
• University of PittsburghGene Therapy in Treating Patients With Advanced Head and Neck Cancer Available from: https://clinicaltri-als.gov/ct2/show/study/NCT00009841?term=gene&cond=Oral+Cancer&draw=3. NLM identifier: NCT00009841Accessed January 10, 2018
   Google Scholar
• ZengQKanterPMDhirRGoodingWEHuangLGrandisJRLack of toxicity of EGFR antisense gene therapyJ Exp Ther Oncol20022317418612415634
   PubMedGoogle Scholar
• BoettcherMMcManusMTChoosing the right tool for the job: RNAi, TALEN, or CRISPRMol Cell201558457558526000843
   PubMed Web of Science ®Google Scholar
• ChiraSGuleiDHajitouABerindan-NeagoeIRestoring the p53 ‘guardian’ phenotype in p53-deficient tumor cells with CRISPR/Cas9Trends Biotechnol Epub2018222
   PubMed Web of Science ®Google Scholar
• GuleiDBerindan-NeagoeICRISPR/Cas9: a potential life-saving tool. What’s next?Mol Ther Nucleic Acids2017933333629246311
   PubMedGoogle Scholar
• CarninciPSandelinALenhardBGenome-wide analysis of mammalian promoter architecture and evolutionNat Genet200638662663516645617
   PubMed Web of Science ®Google Scholar