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Original Research

Macropinocytosis activated by oncogenic Dbl enables specific targeted delivery of Tat/pDNA nano-complexes into ovarian cancer cells

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Pages 4895-4911 | Published online: 30 Aug 2018

References

  • WangKHuangQQiuFSuiMNon-viral delivery systems for the application in p53 cancer gene therapyCurr Med Chem201522354118413626423086
  • LehtoTKurrikoffKLangelÜCell-penetrating peptides for the delivery of nucleic acidsExpert Opin Drug Deliv20129782383622594635
  • KurrikoffKGestinMLangelÜRecent in vivo advances in cell-penetrating peptide-assisted drug deliveryExpert Opin Drug Deliv201613337338726634750
  • EliyahuHServelNDombAJBarenholzYLipoplex-induced hemagglutination: potential involvement in intravenous gene deliveryGene Ther200291385085812080379
  • AramakiYTakanoSTsuchiyaSInduction of apoptosis in macrophages by cationic liposomesFEBS Lett1999460347247610556519
  • CerratoCPLehtoTLangelÜPeptide-based vectors: recent developmentsBiomol Concepts20145647948825429600
  • WittrupAZhangSHBeltingMStudies of proteoglycan involvement in CPP-mediated deliveryMethods Mol Biol20116839911521053125
  • AlhakamyNANigatuASBerklandCJRamseyJDNoncovalently associated cell-penetrating peptides for gene delivery applicationsTher Deliv20134674175723738670
  • MargusHPadariKPoogaMCell-penetrating peptides as versatile vehicles for oligonucleotide deliveryMol Ther201220352553322233581
  • ZhangBWangKSiJSuiMShenYCharge-reversal polymers for biodeliveryGuZBioinspired and Biomimetic Polymer Systems for Drug and Gene DeliveryWeinheimWiley-VCH Verlag GmbH & Co. KGaA2014223242
  • KellerAAMussbachFBreitlingRRelationships between cargo, cell penetrating peptides and cell type for uptake of non-covalent complexes into live cellsPharmaceuticals (Basel)20136218420324275947
  • WangWAbbadSZhangZWangSZhouJLvHCell-penetrating peptides for cancer-targeting therapy and imagingCurr Cancer Drug Targets201515433735125669720
  • JobinMLAlvesIDOn the importance of electrostatic interactions between cell penetrating peptides and membranes: a pathway toward tumor cell selectivity?Biochimie2014107Pt A15415925107405
  • MacewanSRChilkotiAHarnessing the power of cell-penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agentsWiley Interdiscip Rev Nanomed Nanobiotechnol201351314822977001
  • IgnatovichIADizheEBPavlotskayaAVComplexes of plasmid DNA with basic domain 47–57 of the HIV-1 Tat protein are transferred to mammalian cells by endocytosis-mediated pathwaysJ Biol Chem200327843426254263612882958
  • HellgrenIGormanJSylvénCFactors controlling the efficiency of Tat-mediated plasmid DNA transferJ Drug Target2004121394715203910
  • RegbergJSrimaneeALangelUApplications of cell-penetrating peptides for tumor targeting and future cancer therapiesPharmaceuticals (Basel)201259991100724280701
  • ShinMCZhangJMinKACell-penetrating peptides: achievements and challenges in application for cancer treatmentJ Biomed Mater Res A2014102257558723852939
  • KhalilIAKogureKFutakiSHarashimaHHigh density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expressionJ Biol Chem200628163544355116326716
  • KaplanIMWadiaJSDowdySFCationic TAT peptide transduction domain enters cells by macropinocytosisJ Control Release2005102124725315653149
  • WadiaJSStanRVDowdySFTransducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosisNat Med200410331031514770178
  • OgnibeneMVanniCSegalerbaDThe tumor suppressor hamartin enhances Dbl protein transforming activity through interaction with ezrinJ Biol Chem201128634299732998321712385
  • KauppinenKPDuanFWelsJIManorDRegulation of the Dbl proto-oncogene by heat shock cognate protein 70 (Hsc70)J Biol Chem200528022216382164415802271
  • VanniCManciniPGaoYRegulation of proto-Dbl by intracellular membrane targeting and protein stabilityJ Biol Chem200227722197451975311907027
  • GaoZNiuXZhangQMitochondria chaperone GRP75 moonlighting as a cell cycle controller to derail endocytosis provides an opportunity for nanomicrosphere intracellular deliveryOncotarget2017835585365855228938577
  • ChenHGaoZHeCGRP75 upregulates clathrin-independent endocytosis through actin cytoskeleton reorganization mediated by the concurrent activation of Cdc42 and RhoAExp Cell Res2016343222323627090015
  • TrabuloSCardosoALManoMde LimaMCCell-penetrating peptides-mechanisms of cellular uptake and generation of delivery systemsPharmaceuticals (Basel)20103496199327713284
  • JulianoRLThe delivery of therapeutic oligonucleotidesNucleic Acids Res201644146518654827084936
  • EgamiYTaguchiTMaekawaMAraiHArakiNSmall GTPases and phosphoinositides in the regulatory mechanisms of macropinosome formation and maturationFront Physiol2014537425324782
  • LinRCerioneRAManorDSpecific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformationJ Biol Chem199927433236332364110438546
  • UedaSKataokaTSatohTRole of the Sec14-like domain of Dbl family exchange factors in the regulation of Rho family GTPases in different subcellular sitesCell Signal200416889990615157669
  • HuangYWLeeHJTolliverLMAronstamRSDelivery of nucleic acids and nanomaterials by cell-penetrating peptides: opportunities and challengesBiomed Res Int2015201583407925883975
  • RaucherDRyuJSCell-penetrating peptides: strategies for anticancer treatmentTrends Mol Med201521956057026186888
  • MuruganKChoonaraYEKumarPBijukumarDdu ToitLCPillayVParameters and characteristics governing cellular internalization and trans-barrier trafficking of nanostructuresInt J Nanomedicine2015102191220625834433
  • SinghJMichelDChitandaJMVerrallREBadeaIEvaluation of cellular uptake and intracellular trafficking as determining factors of gene expression for amino acid-substituted gemini surfactant-based DNA nanoparticlesJ Nanobiotechnology201210722296763
  • MercerJHeleniusAVirus entry by macropinocytosisNat Cell Biol200911551052019404330
  • BoltonSJJonesDNDarkerJGEgglestonDSHunterAJWalshFSCellular uptake and spread of the cell-permeable peptide penetratin in adult rat brainEur J Neurosci20001282847285510971627
  • LimKJSungBHShinJRA cancer specific cell-penetrating peptide, BR2, for the efficient delivery of an scFv into cancer cellsPLoS One201386e6608423776609
  • AgarwalRSinghVJurneyPShiLSreenivasanSVRoyKMammalian cells preferentially internalize hydrogel nanodiscs over nanorods and use shape-specific uptake mechanismsProc Natl Acad Sci U S A201311043172471725224101456
  • Martin-PerezJBar-ZviDBrantonDEriksonRLTransformation by Rous sarcoma virus induces clathrin heavy chain phosphorylationJ Cell Biol198910925775842547803
  • ZhuKDebreceniBBiFZhengYOligomerization of DH domain is essential for Dbl-induced transformationMol Cell Biol200121242543711134331
  • NakaseIKobayashiNBTakatani-NakaseTYoshidaTActive macro-pinocytosis induction by stimulation of epidermal growth factor receptor and oncogenic Ras expression potentiates cellular uptake efficacy of exosomesSci Rep201551030026036864
  • CommissoCDavidsonSMSoydaner-AzelogluRGMacropinocytosis of protein is an amino acid supply route in Ras-transformed cellsNature2013497745163363723665962
  • HawkinsPTStephensLREmerging evidence of signalling roles for PI(3,4)P2 in Class I and II PI3K-regulated pathwaysBiochem Soc Trans201644130731426862220
  • OzdenerGBBaisMVTrackmanPCDetermination of cell uptake pathways for tumor inhibitor lysyl oxidase propeptideMol Oncol201610112326297052
  • JaiswalMDvorskyRAhmadianMRDeciphering the molecular and functional basis of Dbl family proteins: a novel systematic approach toward classification of selective activation of the Rho family proteinsJ Biol Chem201328864486450023255595