Doxorubicin-loaded protease-activated near-infrared fluorescent polymeric nanoparticles for imaging and therapy of cancer

References

• JemalATiwariRCMurrayTCancer statistics, 2004CA Cancer J Clin200454182914974761
   PubMed Web of Science ®Google Scholar
• DataWCRFfor cancer frequency by country: World Cancer Research Fund InternationalWorld Cancer Res Fund2017
   Google Scholar
• American Cancer SocietyCancer Facts & Figures2016AtlantaAmerican Cancer Society2016 Available from: https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2016/cancer-facts-and-figures-2016.pdfAccessed October 4, 2018
   Google Scholar
• DeSantisCMaJBryanLJemalAStatistics BcancerBreast cancer statistics, 2013CA Cancer J Clin2014641526224114568
   PubMed Web of Science ®Google Scholar
• GiacconeGPinedoHMResistanceDDrug ResistanceOncologist199611 & 2828710387972
   PubMedGoogle Scholar
• XuXXieKZhangXQEnhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrugProc Natl Acad Sci U S A201311046186381864324167294
   PubMed Web of Science ®Google Scholar
• duYRenWLiYThe enhanced chemotherapeutic effects of doxorubicin loaded PEG coated TiO2 nanocarriers in an orthotopic breast tumor bearing mouse modelJ Mater Chem B20153815181528
   PubMed Web of Science ®Google Scholar
• ChenAMZhangMWeiDCo-delivery of doxorubicin and Bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cellsSmall20095232673267719780069
   PubMed Web of Science ®Google Scholar
• WangHZhaoYWuYEnhanced anti-tumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxy PEG-PLGA copolymer nanoparticlesBiomaterials201132328281829021807411
   PubMed Web of Science ®Google Scholar
• WangHLuZWangLNew generation nanomedicines constructed from self-assembling small-molecule prodrugs alleviate cancer drug toxicityCancer Res201777246963697429055017
   PubMed Web of Science ®Google Scholar
• WangHWuJXieKPrecise Engineering of Prodrug Cocktails into Single Polymeric Nanoparticles for Combination Cancer Therapy: Extended and Sequentially Controllable Drug ReleaseACS Appl Mater Interfaces2017912105671057628271714
   PubMed Web of Science ®Google Scholar
• WangHXieHWuJStructure-Based Rational Design of Prodrugs to Enable Their Combination with Polymeric Nanoparticle Delivery Platforms for Enhanced Antitumor EfficacyAngew Chemie Int Ed2014531153211537
   PubMed Web of Science ®Google Scholar
• WangHChenJXuCCancer nanomedicines stabilized by π-π stacking between heterodimeric prodrugs enable exceptionally high drug loading capacity and safer delivery of drug combinationsTheranostics20177153638365229109766
   PubMed Web of Science ®Google Scholar
• TaurinSGreishKEnhanced Vascular Permeability in Solid Tumors: A Promise for Anticancer NanomedicineTight Junctions in Cancer MetastasisMartinTAJiangWGVol DordrechtSpringer Netherlands201381118
   Google Scholar
• LammersTKiesslingFHenninkWEStormGNanotheranosticsSGNanotheranostics and image-guided drug delivery: current concepts and future directionsMol Pharm2010761899191220822168
   PubMed Web of Science ®Google Scholar
• WeisslederRPittetMJImaging in the era of molecular oncologyNature2008452718758058918385732
   PubMed Web of Science ®Google Scholar
• TobisSKnopfJSilversCNear infrared fluorescence imaging with robotic assisted laparoscopic partial nephrectomy: initial clinical experience for renal cortical tumorsJ Urol20111861475221571337
   PubMed Web of Science ®Google Scholar
• SchlottmannFPattiMGEvaluation of Gastric Conduit Perfusion During Esophagectomy with Indocyanine Green Fluorescence ImagingJ Laparoendosc Adv Surg Tech A201727121305130828817358
   PubMed Web of Science ®Google Scholar
• BoniLDavidGManganoAClinical applications of indocyanine green (ICG) enhanced fluorescence in laparoscopic surgerySurg Endosc20152972046205525303914
   PubMed Web of Science ®Google Scholar
• CurrieACBrigicAThomas-GibsonSA pilot study to assess near infrared laparoscopy with indocyanine green (ICG) for intraoperative sentinel lymph node mapping in early colon cancerEur J Surg Oncol201743112044205128919031
   PubMed Web of Science ®Google Scholar
• BernardMEGlaserSMGillBSNagayaTNakamuraYAChoykePLResults of a Single Institution Experience with Dose-Escalated Chemoradiation for Locally Advanced Unresectable Non-Small Cell Lung CancerFront Oncol2017731411628168163
   PubMedGoogle Scholar
• TipirneniKEWarramJMMooreLSOncologic Procedures Amenable to Fluorescence-guided SurgeryAnn Surg20172661364728045715
   PubMed Web of Science ®Google Scholar
• de BoerEWarramJMTuckerMDIn Vivo Fluorescence Immunohistochemistry: Localization of Fluorescently Labeled Cetuximab in Squamous Cell CarcinomasSci Rep201551016926120042
   PubMed Web of Science ®Google Scholar
• WhitleyMJCardonaDMLazaridesALA mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancerSci Transl Med20168320320ra4
   Google Scholar
• PeekMCCharalampoudisPAnningaBBakerRDouekMBlue dye for identification of sentinel nodes in breast cancer and malignant melanoma: a systematic review and meta-analysisFuture Oncol201713545546727578614
   PubMed Web of Science ®Google Scholar
• OgataFNarushimaMMiharaMAzumaRMorimotoYKoshimaIIntraoperative lymphography using indocyanine green dye for near-infrared fluorescence labeling in lymphedemaAnn Plast Surg200759218018417667413
   PubMed Web of Science ®Google Scholar
• ChangDWSuamiHSkorackiRA prospective analysis of 100 consecutive lymphovenous bypass cases for treatment of extremity lymphedemaPlast Reconstr Surg201313251305131424165613
   PubMed Web of Science ®Google Scholar
• AldaveGTejadaSPayEPrognostic value of residual fluorescent tissue in glioblastoma patients after gross total resection in 5-aminolevulinic Acid-guided surgeryNeurosurgery201372691592123685503
   PubMed Web of Science ®Google Scholar
• UnkartJTChenSLWapnirILGonzálezJEHarootunianAWallaceAMIntraoperative Tumor Detection Using a Ratiometric Activatable Fluorescent Peptide: A First-in-Human Phase 1 StudyAnn Surg Oncol201724113167317328699134
   PubMed Web of Science ®Google Scholar
• TummersQRHoogstinsCEGaarenstroomKNIntraoperative imaging of folate receptor alpha positive ovarian and breast cancer using the tumor specific agent EC17Oncotarget2016722321443215527014973
   PubMedGoogle Scholar
• PatelSKJanjicJMMacrophage targeted theranostics as personalized nanomedicine strategies for inflammatory diseasesTheranostics20155215017225553105
   PubMed Web of Science ®Google Scholar
• SinghAVKhareMGadeWNZamboniPTheranostic implications of nanotechnology in multiple sclerosis: a future perspectiveAutoimmune Dis20122012112
   Google Scholar
• McCarthyJRKorngoldEWeisslederRJafferFAA light-activated theranostic nanoagent for targeted macrophage ablation in inflammatory atherosclerosisSmall20106182041204920721949
   PubMed Web of Science ®Google Scholar
• CrielaardBJLammersTSchiffelersRMStormGDrug targeting systems for inflammatory disease: one for all, all for oneJ Control Release2012161222523422226771
   PubMed Web of Science ®Google Scholar
• AulićSBolognesiMLLegnameGSmall-molecule theranostic probes: a promising future in neurodegenerative diseasesInt J Cell Biol2013201315095224324497
   PubMedGoogle Scholar
• BolognesiMLGandiniAPratiFUliassiEFrom Companion Diagnostics to Theranostics: A New Avenue for Alzheimer’s Disease?J Med Chem201659177759777027124551
   PubMed Web of Science ®Google Scholar
• WangPMooreATheranostic magnetic resonance imaging of type 1 diabetes and pancreatic islet transplantationQuant Imaging Med Surg20122315116223256077
   PubMedGoogle Scholar
• WangPMooreATheranostic MRI: the future for Type 1 diabetes management?Imaging Med2014612539
   Google Scholar
• HowellMWangCMahmoudAHellermannGMohapatraSSMohapatraSDual-function theranostic nanoparticles for drug delivery and medical imaging contrast: perspectives and challenges for use in lung diseasesDrug Deliv Transl Res20133435236323936754
   PubMed Web of Science ®Google Scholar
• MccarthyJRMultifunctional agents for concurrent imaging and therapy in cardiovascular diseaseAdv Drug Deliv Rev201062111023103020654664
   PubMed Web of Science ®Google Scholar
• WangDLinBAiHTheranostic nanoparticles for cancer and cardiovascular applicationsPharm Res20143161390140624595494
   PubMed Web of Science ®Google Scholar
• XieJLeeSChenXNanoparticle-based theranostic agentsAdv Drug Deliv Rev201062111064107920691229
   PubMed Web of Science ®Google Scholar
• ZhuXAnquillareELBFarokhzadOCShiJPolymer- and Protein-Based Nanotechnologies for Cancer TheranosticsCancer Theranostics2014419436
   Google Scholar
• MohanPRapoportNDoxorubicin as a molecular nanotheranostic agent: effect of doxorubicin encapsulation in micelles or nanoemulsions on the ultrasound-mediated intracellular delivery and nuclear traffickingMol Pharm2010761959197320957997
   PubMed Web of Science ®Google Scholar
• CummingsJSmythJFDNA topoisomerase I and II as targets for rational design of new anticancer drugsAnn Oncol1993475335438395870
   PubMed Web of Science ®Google Scholar
• FornariFARandolphJKYalowichJCRitkeMKGewirtzDAInterference by doxorubicin with DNA unwinding in MCF-7 breast tumor cellsMol Pharmacol19944546496568183243
   PubMed Web of Science ®Google Scholar
• GabizonAShmeedaHBarenholzYPharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studiesClin Pharmacokinet200342541943612739982
   PubMed Web of Science ®Google Scholar
• GabizonAALiposomal drug carrier systems in cancer chemotherapy: current status and future prospectsJ Drug Target200210753553812683720
   PubMed Web of Science ®Google Scholar
• HollidayDLSpeirsVChoosing the right cell line for breast cancer researchBreast Cancer Res201113421521884641
   PubMed Web of Science ®Google Scholar
• TuzlaliSPathology of Breast CancerBreast Disease: Diagnosis and PathologyVol. 120151241266
   Google Scholar
• HilgerIHergtRKaiserWAUse of magnetic nanoparticle heating in the treatment of breast cancerIEE Proc Nanobiotechnol20051521333916441156
   PubMedGoogle Scholar
• OndaNKemmochiSMoritaRIshiharaYShibutaniMIn vivo imaging of tissue-remodeling activity involving infiltration of macrophages by a systemically administered protease-activatable probe in colon cancer tissuesTransl Oncol201366628IN424466365
   PubMed Web of Science ®Google Scholar
• MitoJKFerrerJMBrigmanBEIntraoperative detection and removal of microscopic residual sarcoma using wide-field imagingCancer2012118215320533022437667
   PubMed Web of Science ®Google Scholar
• MieogJSHuttemanMvan der VorstJRImage-guided tumor resection using real-time near-infrared fluorescence in a syngeneic rat model of primary breast cancerBreast Cancer Res Treat2011128367968920821347
   PubMed Web of Science ®Google Scholar
• ReubiJCPeptide receptors as molecular targets for cancer diagnosis and therapyEndocr Rev200324438942712920149
   PubMed Web of Science ®Google Scholar
• WeisslederRTungCHMahmoodUBogdanovAIn vivo imaging of tumors with protease-activated near-infrared fluorescent probesNat Biotechnol199917437537810207887
   PubMed Web of Science ®Google Scholar
• TungCHBredowSMahmoodUWeisslederRPreparation of a cathepsin D sensitive near-infrared fluorescence probe for imagingBioconjug Chem199910589289610502358
   PubMed Web of Science ®Google Scholar
• LeeSParkKLeeSYDark quenched matrix metalloproteinase fluorogenic probe for imaging osteoarthritis development in vivoBioconjug Chem20081991743174718729392
   PubMed Web of Science ®Google Scholar
• BremerCTungCHWeisslederRIn vivo molecular target assessment of matrix metalloproteinase inhibitionNat Med20017674374811385514
   PubMed Web of Science ®Google Scholar
• LeeSKHanMSTungCHLayered nanoprobe for long-lasting fluorescent cell labelSmall20128213315332022888056
   PubMed Web of Science ®Google Scholar
• RakashSRole of proteases in cancer: A reviewBiotechnol Mol Biol Rev20127490101
   Google Scholar
• SoreideKJanssenEAKörnerHBaakJPTrypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasisJ Pathol2006209214715616691544
   PubMed Web of Science ®Google Scholar
• GeLShenoySKLefkowitzRJDefeaKConstitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2J Biol Chem200427953554195542415489220
   PubMed Web of Science ®Google Scholar
• SuSLiYLuoYProteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migrationOncogene200928343047305719543320
   PubMed Web of Science ®Google Scholar
• MatějRMandákováPNetíkováIPouckováPOlejárTProteinase-activated receptor-2 expression in breast cancer and the role of trypsin on growth and metabolism of breast cancer cell line MDA MB-231Physiol Res200756447548416925462
   PubMed Web of Science ®Google Scholar
• MorrisDRDingYRicksTKGullapalliAWolfeBLTrejoJProtease-activated receptor-2 is essential for factor VIIa and Xa-induced signaling, migration, and invasion of breast cancer cellsCancer Res200666130731416397244
   PubMed Web of Science ®Google Scholar
• ÖzelTWhiteSNguyenEEnzymatically activated near infrared nanoprobes based on amphiphilic block copolymers for optical detection of cancerLasers Surg Med201547757959426189505
   PubMed Web of Science ®Google Scholar
• HamonCLDorseyCLÖzelTBarnesEMHudnallTWBetancourtTNear-infrared fluorescent aza-BODIPY dye-loaded biodegradable polymeric nanoparticles for optical cancer imagingJ Nanoparticle Res2016187207
   Web of Science ®Google Scholar
• FoySPStineAJainTKLabhasetwarVMagnetic Nanoparticles for Drug Delivery Methods in Bioengineering: Nanoscale Bioengineering and NanomedicineRegeKMedintzIgorLVol BostonArtech House2009123136
   Google Scholar
• BetancourtTBrownBBrannon-PeppasLDoxorubicin-loaded PLGA nanoparticles by nanoprecipitation: preparation, characterization and in vitro evaluationNanomedicine20072221923217716122
   PubMed Web of Science ®Google Scholar
• KaszubaMCorbettJWatsonFMJonesAHigh-concentration zeta potential measurements using light-scattering techniquesPhilos Trans A Math Phys Eng Sci201036819274439445120732896
   PubMed Web of Science ®Google Scholar
• AlexisFPridgenEMolnarLKFarokhzadOCFactors affecting the clearance and biodistribution of polymeric nanoparticlesMol Pharm20085450551518672949
   PubMed Web of Science ®Google Scholar
• LedetGMandalTKNanomedicine: Emerging therapeutics for the 21st centuryUS Pharm201237711
   Google Scholar
• OlsonESJiangTAguileraTAActivatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteasesProc Natl Acad Sci U S A201010794311431620160077
   PubMed Web of Science ®Google Scholar
• FunovicsMWeisslederRTungCHProtease sensors for bioimagingAnal Bioanal Chem2003377695696312955390
   PubMed Web of Science ®Google Scholar
• ChoiYWeisslederRTungCHSelective antitumor effect of novel protease-mediated photodynamic agentCancer Res200666147225722916849570
   PubMed Web of Science ®Google Scholar
• PeppasNAAnalysis of Fickian and non-Fickian drug release from polymersPharm Acta Helv19856041101114011621
   PubMedGoogle Scholar
• SiepmannJPeppasNADerivation Higuchi Equation: applications, use and misuseInt J Pharm2011418161221458553
   PubMed Web of Science ®Google Scholar
• RitgerPLPeppasNAA simple equation for description of solute releaseJ Control Release198752336
   Google Scholar
• WangPHenningSMHeberDLimitations OfMTTLimitations of MTT and MTS-based assays for measurement of antiproliferative activity of green tea polyphenolsPLoS One201054e1020220419137
   PubMed Web of Science ®Google Scholar
• CiavattaMLLefrancFCarboneMMarine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy ResistanceMed Res Rev201737470280127925266
   PubMed Web of Science ®Google Scholar
• WongHLRauthAMBendayanRA new polymer-lipid hybrid nanoparticle system increases cytotoxicity of doxorubicin against multidrug-resistant human breast cancer cellsPharm Res20062371574158516786442
   PubMed Web of Science ®Google Scholar
• LeeESNaKBaeYHDoxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumorJ Control Release2005103240541815763623
   PubMed Web of Science ®Google Scholar
• TorchilinVPStrategies and Means for Drug Targeting: An Overview Biomedical Aspects of Drug TargetingMuzykantovVTorchilinVBoston MASpringer2002326
   Google Scholar
• MissirlisDKawamuraRTirelliNHubbellJADoxorubicin encapsulation and diffusional release from stable, polymeric, hydrogel nanoparticlesEur J Pharm Sci200629212012916904301
   PubMed Web of Science ®Google Scholar
• KataokaKMatsumotoTYokoyamaMDoxorubicin-loaded poly(ethylene glycol)-poly(β-benzyl-l-aspartate) copolymer micelles: Their pharmaceutical characteristics and biological significanceJournal of Controlled Release20006414315310640653
   PubMed Web of Science ®Google Scholar
• KataokaKMatsumotoTYokoyamaMDoxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-l-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significanceJ Control Release2000641–314315310640653
   PubMed Web of Science ®Google Scholar
• SainiSSinghHBagchiBFluorescence resonance energy transfer (FRET) in chemistry and biology: Non-Förster distance dependence of the FRET rateJ Chem Sci200611812335
   Web of Science ®Google Scholar
• HuangBXKimHYDassCProbing three-dimensional structure of bovine serum albumin by chemical cross-linking and mass spectrometryJ Am Soc Mass Spectrom20041581237124715276171
   PubMed Web of Science ®Google Scholar
• PengCLShihYHLeePCHsiehTMLuoTYShiehMJMulti-modal image-guided photothermal therapy mediated by 188Re-labeled micelles containing a cyanine-type photosensitizerACS Nano2011575594560721671580
   PubMed Web of Science ®Google Scholar
• UpponiJRJerajaniKNageshaDKPolymeric micelles: Theranostic co-delivery system for poorly water-soluble drugs and contrast agentsBiomaterials2018170263629649747
   PubMed Web of Science ®Google Scholar
• TsaiHCChangWHLoCLGraft and diblock copolymer multifunctional micelles for cancer chemotherapy and imagingBiomaterials20103182293230120042234
   PubMed Web of Science ®Google Scholar
• CaiHWangXZhangHEnzyme-sensitive biodegradable and multifunctional polymeric conjugate as theranostic nanomedicineAppl Mater Today201811207218
   Web of Science ®Google Scholar
• LiuYLiJLiuFTheranostic polymeric micelles for the diagnosis and treatment of hepatocellular carcinomaJ Biomed Nanotechnol201511461362226310068
   PubMed Web of Science ®Google Scholar
• LiuYFengLLiuTMultifunctional pH-sensitive polymeric nanoparticles for theranostics evaluated experimentally in cancerNanoscale2014663231324224500240
   PubMed Web of Science ®Google Scholar
• LiuPYuHSunYZhuMDuanYA mPEG-PLGA-b-PLL copolymer carrier for adriamycin and siRNA deliveryBiomaterials201233174403441222436800
   PubMed Web of Science ®Google Scholar
• CraparoEFLicciardiMConigliaroAHepatocyte-targeted fluorescent nanoparticles based on a polyaspartamide for potential theranostic applicationsPolymer201570257270
   Web of Science ®Google Scholar