References
- da SilvaALCruzFFRoccoPRMMoralesMMNew perspectives in nanotherapeutics for chronic respiratory diseasesBiophys Rev20179579380328914424
- WenRBanikBPathakRKKumarAKolishettiNDharSNanotechnology inspired tools for mitochondrial dysfunction related diseasesAdv Drug Deliv Rev201699Pt A526926776231
- PathakKRaghuvanshiSOral bioavailability: issues and solutions via nanoformulationsClin Pharmacokinet201554432535725666353
- BaruaSMitragotriSChallenges associated with penetration of nano-particles across cell and tissue barriers: A review of current status and future prospectsNano Today20149222324325132862
- JmYYjLQiuLYJinYPolymeric nanoparticles of cholesterol-modified glycol chitosan for doxorubicin delivery: preparation and in-vitro and in-vivo characterizationJ Pharm Pharmacol20096171371919505361
- JohnstonHBrownDKermanizadehAGubbinsEStoneVInvestigating the relationship between nanomaterial hazard and physicochemical properties: Informing the exploitation of nanomaterials within therapeutic and diagnostic applicationsJ Control Release2012164330731322940205
- DingCLiZA review of drug release mechanisms from nanocarrier systemsMater Sci Eng C Mater Biol Appl2017761440145328482511
- KermanizadehAJantzenKBrownDMMøllerPLoftSA flow cytometry-based method for the screening of nanomaterial-induced reactive oxygen species production in leukocytes subpopulations in whole bloodBasic Clin Pharmacol Toxicol2018122114915628691406
- LanoneSAndujarPKermanizadehABoczkowskiJDeterminants of carbon nanotube toxicityAdv Drug Deliv Rev201365152063206923928473
- Vega-VilaKRTakemotoJKYanezJARemsbergCMForrestMLDaviesNMClinical toxicities of nanocarrier systemsAdv Drug Deliv Rev20086092993818313790
- ShenXLiTChenZLuminescent/magnetic PLGA-based hybrid nanocomposites: a smart nanocarrier system for targeted codelivery and dual-modality imaging in cancer theranosticsInt J Nanomedicine2017124299432228652734
- KermanizadehAVilladsenKØstremRGJensenKJMøllerPLoftSIntegrin targeting and toxicological assessment of peptide-conjugated liposome delivery systems to activated endothelial cellsBasic Clin Pharmacol Toxicol2017120438038927767251
- GrimaldiAMIncoronatoMSalvatoreMSoricelliANanoparticle-based strategies for cancer immunotherapy and immunodiagnosticsNanomedicine201712192349236528868980
- SilvaACSantosDFerreiraDLopesCMLipid-based nanocarriers as an alternative for oral delivery of poorly water-soluble drugs: peroral and mucosal routesCurr Med Chem201219264495451022834821
- de SioLCaraccioloGPlacidoTApplications of nanomaterials in modern medicineRendiconti Lincei201526S2231237
- TathamLMRannardSPOwenANanoformulation strategies for the enhanced oral bioavailability of antiretroviral therapeuticsTher Deliv20156446949025996045
- BraakhuisHMKloetSKKezicSProgress and future of in vitro models to study translocation of nanoparticlesArch Toxicol20158991469149525975987
- RichardJChallenges in oral peptide delivery: lessons learnt from the clinic and future prospectsTher Deliv20178866368428730934
- PowellJJFariaNThomas-MckayEPeleLCOrigin and fate of dietary nanoparticles and microparticles in the gastrointestinal tractJ Autoimmun2010343J226J23320096538
- PanyalaAChindeSKumariSIGroverPAssessment of genotoxicity and biodistribution of nano- and micron-sized yttrium oxide in rats after acute oral treatmentJ Appl Toxicol201737121379139528685832
- FröhlichERobleggEOral uptake of nanoparticles: human relevance and the role of in vitro systemsArch Toxicol201690102297231427342244
- World Health Organisation International classification of disease, 11th version Available from: http://www.who.int/classifications/icd/en/Accessed July 18, 2018
- ThamphiwatanaSGaoWObonyoMZhangLIn vivo treatment of Helicobacter pylori infection with liposomal linolenic acid reduces colonization and ameliorates inflammationProc Natl Acad Sci U S A201411149176001760525422427
- AlaiMLinWJApplication of nanoparticles for oral delivery of acid-labile lansoprazole in the treatment of gastric ulcer: in vitro and in vivo evaluationsInt J Nanomedicine2015104029404126124659
- XiaoBLarouiHViennoisENanoparticles with surface antibody against CD98 and carrying CD98 small interfering RNA reduce colitis in miceGastroenterology201414651289130024503126
- MoulariBPertuitDPellequerYLamprechtAThe targeting of surface modified silica nanoparticles to inflamed tissue in experimental colitisBiomaterials200829344554456018790531
- BevivinoGMonteleoneGAdvances in understanding the role of cytokines in inflammatory bowel diseaseExpert Rev Gastroenterol Hepatol201812990791530024302
- GreishKTahaSJasimAStyrene maleic acid encapsulated raloxifene micelles for management of inflammatory bowel diseaseClin Transl Med2017612828770521
- ChenYLiuJYangXZhaoXXuHOleanolic acid nanosuspensions: preparation, in-vitro characterization and enhanced hepatoprotective effectJ Pharm Pharmacol200557225926415720792
- DingXYHongCJLiuYTissue distribution, and metabolites of a polyvinylpyrrolidone coated norcantharidin chitosan nanoparticle formulation in rats and mice, using LC-MS/MSInt J Nanomedicine201271723173522619523
- ZhangHPLiGQGuoWZOridonin synergistically enhances JQ1-triggered apoptosis in hepatocellular cancer cells through mitochondrial pathwayOncotarget201786310683310684329290992
- LiuYLiuJLiangJMucosal transfer of wheat germ agglutinin modified lipid-polymer hybrid nanoparticles for oral delivery of ori-doninNanomedicine20171372219222928539275
- NekkantiVRuedaJWangZBetageriGVComparative evaluation of proliposomes and self micro-emulsifying drug delivery system for improved oral bioavailability of nisoldipineInt J Pharm20165051–2798827041124
- KrishnamoorthyBHabibur RahmanSMTamil SelvanNDesign, formulation, in vitro, in vivo, and pharmacokinetic evaluation of nisoldipine-loaded self-nanoemulsifying drug delivery systemJ Nanoparticle Res201517134
- BegSSharmaGThankiKJainSKatareOPSinghBPositively charged self-nanoemulsifying oily formulations of olmesartan medox-omil: Systematic development, in vitro, ex vivo and in vivo evaluationInt J Pharm20154931–246648226211900
- QiRZhangHXuLG5 PAMAM dendrimer versus liposome: A comparison study on the in vitro transepithelial transport and in vivo oral absorption of simvastatinNanomedicine20151151141115125791813
- LzLTongCQYuJHanMGaoJQMechanism of enhanced oral absorption of hydrophilic drug incorporated in hydrophobic nanoparticlesInt J Nanomedicine201382709271723935363
- PerroneDArditoFGiannatempoGBiological and therapeutic activities, and anticancer properties of curcuminExp Ther Med20151051615162326640527
- SunMZhaoLGuoCEvaluation of an oral carrier system in rats: bioavailability and gastrointestinal absorption properties of curcumin encapsulated PBCA nanoparticlesJ Nanoparticle Res2012142705
- SunWZouYGuoYConstruction and characterization of curcumin nanoparticles systemJ Nanoparticle Res20141632317
- HarigaeTNakagawaKMiyazawaTMetabolic fate of poly-(lactic-co-glycolic acid)-based curcumin nanoparticles following oral administrationInt J Nanomedicine2016113009302227418823
- KimMSSoluplus-coated colloidal silica nanomatrix system for enhanced supersaturation and oral absorption of poorly water-soluble drugsArtif Cells Nanomed Biotechnol201341636336723336707
- ZhangZHZhangYLZhouJPHxLSolid lipid nanoparticles modified with stearic acid-octaarginine for oral administration of insulinInt J Nanomedicine201273333333922848162
- LiuJYangKXiaoWGLP-1 receptor agonists stimulate ANGPTL8 production through the PI3K/Akt pathway in a GLP-1 receptor-dependent mannerPeptides2018106839030003931
- QuWLiYHovgaardLA silica-based pH-sensitive nano-matrix system improves the oral absorption and efficacy of incre-tin hormone glucagon-like peptide-1Int J Nanomedicine201274983499423028226
- TranKLParkYIPandyaSOverview of glucagon-like peptide-1 receptor agonists for the treatment of patients with type 2 diabetesAm Health Drug Benefits20171017818828794822
- LiXWangCLiangRThe glucose-lowering potential of exenatide delivered orally via goblet cell-targeting nanoparticlesPharm Res2015321017102725270570
- XiongXYLiQHLiYPGuoLLiZLGongYCPluronic P85/poly(lactic acid) vesicles as novel carrier for oral insulin deliveryColloids Surf B Biointerfaces201311128228823838194
- RafieiPHaddadiAPharmacokinetic consequences of PLGA nano-particles in Docetaxel drug deliveryPharm Nanotechnol20175132328948907
- PicardMManagement of Hypersensitivity Reactions to TaxanesImmunol Allergy Clin North Am201737467969328965634
- ChoHJParkJWYoonISKimDDSurface-modified solid lipid nano-particles for oral delivery of docetaxel: enhanced intestinal absorption and lymphatic uptakeInt J Nanomedicine2014949550424531717
- HuKCaoSHuFFengJEnhanced oral bioavailability of docetaxel by lecithin nanoparticles: preparation, in vitro, and in vivo evaluationInt J Nanomedicine201273537354522848177
- LiuYZhaiYHanXBioadhesive chitosan-coated cyclodextrin-based superamolecular nanomicelles to enhance the oral bioavailability of doxorubicinJ Nanoparticle Res201416102587
- EloyJOPetrilliRChescaDLSaggioroFPLeeRJMarchettiJMAnti-HER2 immunoliposomes for co-delivery of paclitaxel and rapamycin for breast cancer therapyEur J Pharm Biopharm201711515916728257810
- LiuFParkJYZhangYTargeted cancer therapy with novel high drug-loading nanocrystalsJ Pharm Sci20109983542355120564383
- ZhaoLFengSSEnhanced oral bioavailability of paclitaxel formulated in vitamin E-TPGS emulsified nanoparticles of biodegradable polymers: in vitro and in vivo studiesJ Pharm Sci20109983552356020564384
- ZengNGaoXHuQLipid-based liquid crystalline nanoparticles as oral drug delivery vehicles for poorly water-soluble drugs: cellular interaction and in vivo absorptionInt J Nanomedicine201273703371822888230
- LiuCLiuDBaiFZhangJZhangNIn vitro and in vivo studies of lipid-based nanocarriers for oral N3-o-toluyl-fluorouracil deliveryDrug Deliv201017535236320387993
- LiuDLiuCZouWZhangNEnhanced gastrointestinal absorption of N3-O-toluyl-fluorouracil by cationic solid lipid nanoparticlesJ Nanoparticle Res2010123975984
- SagnellaSMGongXMoghaddamMJNanostructured nanoparticles of self-assembled lipid pro-drugs as a route to improved chemotherapeutic agentsNanoscale20113391992421173998
- NasrinAHassanMYePInhibition of Notch signaling pathway using γ-secretase inhibitor delivered by a low dose of Triton-X100 in cultured oral cancer cellsBiochem Biophys Res Commun201849532118212429253571
- DesaiDPrabhakarNMamaevaVTargeted modulation of cell differentiation in distinct regions of the gastrointestinal tract via oral administration of differently PEG-PEI functionalized mesoporous silica nanoparticlesInt J Nanomedicine20161129931326855569
- KawamotoRYamashitaANishihiraKDifferent inflammatory response and oxidative stress in neointimal hyperplasia after balloon angioplasty and stent implantation in cholesterol-fed rabbitsPathol Res Pract2006202644745616635553
- ZhangZCaoHJiangSNanoassembly of probucol enables novel therapeutic efficacy in the suppression of lung metastasis of breast cancerSmall201410224735474524930590
- BoakyeCHPatelKPatelARLipid-based oral delivery systems for skin deposition of a potential chemopreventive DIM derivative: characterization and evaluationDrug Deliv Transl Res20166552653927405772
- PangeniRChoiSWJeonOCByunYParkJWMultiple nanoemulsion system for an oral combinational delivery of oxaliplatin and 5-fluorouracil: preparation and in vivo evaluationInt J Nanomedicine2016116379639927942212
- SandhuPSKumarRBegSNatural lipids enriched self-nano-emulsifying systems for effective co-delivery of tamoxifen and narin-genin: Systematic approach for improved breast cancer therapeuticsNanomedicine20171351703171328343014
- JinXZhangZSunEEnhanced oral absorption of 20(S)-protopanaxadiol by self-assembled liquid crystalline nanoparticles containing piperine: in vitro and in vivo studiesInt J Nanomedicine2013864165223426652
- ZhangZLiMWangHAgrawalSZhangRAntisense therapy targeting MDM2 oncogene in prostate cancer: effects on proliferation, apoptosis, multiple gene expression, and chemotherapyPNAS2003100116361164113130078
- VorugantiSQinJJSarkarSOral nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of actionOncotarget20156213792139426041888
- ChenWLYuanZQLiuYLiposomes coated with N-trimethyl chitosan to improve the absorption of harmine in vivo and in vitroInt J Nanomedicine20161132533626855571
- DangHMengMHWZhaoHLuteolin-loaded solid lipid nanoparticles synthesis, characterization, & improvement of bioavailability, pharmacokinetics in vitro and vivo studiesJ Nanoparticle Res20141642347
- ShaSVongLBChonpathompikunlertPYoshitomiTMatsuiHNagasakiYSuppression of NSAID-induced small intestinal inflammation by orally administered redox nanoparticlesBiomaterials201334338393840023896000
- HillaireauHDereuddre-BosquetNSkanjiRAnti-HIV efficacy and biodistribution of nucleoside reverse transcriptase inhibitors delivered as squalenoylated prodrug nanoassembliesBiomaterials201334204831483823562054
- JinYXinRTongLduLLiMCombination anti-HIV therapy with the self-assemblies of an asymmetric bolaamphiphilic zidovudine/didanosine prodrugMol Pharm20118386787621553876
- McdonaldTOGiardielloMMartinPAntiretroviral solid drug nanoparticles with enhanced oral bioavailability: production, characterization, and in vitro-in vivo correlationAdv Healthc Mater20143340041123997027
- SkanjiRAndrieuxKLalanneMA new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuaryInt J Pharm20114141–228529721596125
- TshweuLKatataLKalomboLEnhanced oral bioavailability of the antiretroviral efavirenz encapsulated in poly(epsilon-caprolactone) nanoparticles by a spray-drying methodNanomedicine20149121821183324364871
- SerranoDRLalatsaADea-AyuelaMAOral particle uptake and organ targeting drives the activity of amphotericin B nanoparticlesMol Pharm201512242043125558881
- OmwoyoWNOgutuBOlooFPreparation, characterization, and optimization of primaquine-loaded solid lipid nanoparticlesInt J Nanomedicine201493865387425143734
- ZhangCPengFLiuWNanostructured lipid carriers as a novel oral delivery system for triptolide: induced changes in pharmacokinetics profile associated with reduced toxicity in male ratsInt J Nanomedicine201491049106324591827
- QiaoHChenLRuiTFabrication and in vitro/in vivo evaluation of amorphous andrographolide nanosuspensions stabilized by d-α-tocopheryl polyethylene glycol 1000 succinate/sodium lauryl sulfateInt J Nanomedicine2017121033104628223797
- YinJXiangCWangPYinYHouYBiocompatible nanoemulsions based on hemp oil and less surfactants for oral delivery of baicalein with enhanced bioavailabilityInt J Nanomedicine2017122923293128435268
- EissaMMEl-MoslemanyRMRamadanAAAmerEIEl-AzzouniMZEl-KhordaguiLKMiltefosine lipid nanocapsules for single dose oral treatment of Schistosomiasis Mansoni: a preclinical studyPLoS One20151011e014178826574746
- CamachoAIIracheJMde SouzaJSánchez-GómezSGamazoCNanoparticle-based vaccine for mucosal protection against Shigella flexneri in miceVaccine201331323288329423727423
- LewittPALevodopa therapy for Parkinson’s disease: Pharmacokinetics and pharmacodynamicsMov Disord2015301647225449210
- KuraAUCheahPSHusseinMZToxicity evaluation of zinc aluminium levodopa nanocomposite via oral route in repeated dose studyNanoscale Res Lett20149126124948886
- ChonpathompikunlertPYoshitomiTVongLBImaizumiNOzakiYNagasakiYRecovery of cognitive dysfunction via orally administered redox-polymer nanotherapeutics in SAMP8 micePLoS One2015105e012601325955022
- TosiGRuoziBBellettiDBrain-targeted polymeric nanoparticles: in vivo evidence of different routes of administration in rodentsNanomedicine2013891373138323565661
- CheLZhouJLiSAssembled nanomedicines as efficient and safe therapeutics for articular inflammationInt J Pharm20124391–230731622989985
- KimuraTA new family of nonsiliceous porous hybrids from bisphosphonatesJ Nanosci Nanotechnol20131342461247023763120
- JungIWHanHKEffective mucoadhesive liposomal delivery system for risedronate: preparation and in vitro/in vivo characterizationInt J Nanomedicine201492299230624872692
- SkrajnowskaDBobrowska-KorczakBTokarzADisorders of mechanisms of calcium metabolism control as potential risk factors of prostate cancerCurr Med Chem201724384229424428901272
- HwangSRSeoDHByunYParkJWThe anti-osteoporotic effects of the orally administered nano-complex were evaluated these animals following oral exposure at doses of 50 µg/kgInt J Nanomedicine2016114231424627621618
- AbramovECassiolaFSchwobOCellular mechanism of oral absorption of solidified polymer micellesNanomedicine2015111993200226247432
- JainSHardeHIndulkarAAgrawalAKImproved stability and immunological potential of tetanus toxoid containing surface engineered bilosomes following oral administrationNanomedicine20141043144024036099
- YpLSunLZYaoLHXiongXYZlLAcute and subacute toxicity studies of Pluronic P85/poly (lactic acid) nanoparticles in miceMicro Nano Lett20138796800
- SemeteBBooysenLLemmerYIn vivo evaluation of the biodistribution and safety of PLGA nanoparticles as drug delivery systemsNanomedicine2010666267120230912
- LeeCMLeeTKKimDIOptical imaging of absorption and distribution of RITC-SiO2 nanoparticles after oral administrationInt J Nanomedicine20149243250
- Brotons-CantoAGamazoCMartín-ArbellaNEvaluation of nanoparticles as oral vehicles for immunotherapy against experimental peanut allergyInt J Biol Macromol201811032833528965967
- HeishHLLeeCHLinKCDevelopment of Yam Dioscorin-loaded nanoparticles for paracellular transport across human intestinal Caco-2 cell monolayersJ Agric Food Chem2018711751183
- LechugaSIvanovAIDisruption of the epithelial barrier during intestinal inflammation: quest for new molecules and mechanismsBiochim Biophys Acta Mol Cell Res1864201711831194
- ChengYEl-KattanAZhangYRayASLaiYInvolvement of drug transporters in organ toxicity: the fundamental basis of drug discovery and developmentChem Res Toxicol201629454556326889774
- TalattofAPriceJCAmidonGLGastrointestinal motility variation and implications for plasma level variation: oral drug productsMol Pharm201613255756726692042
- LopesCMBettencourtCRossiAButtiniFBarataPOverview on gastroretentive drug delivery systems for improving drug bioavailabilityInt J Pharm2016510114415827173823
- McdermottJScholesPFormulation design space: a proven approach to maximize flexibility and outcomes within early clinical developmentTher Deliv201561112681278
- ShekhawatPBPokharkarVBUnderstanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdlesActa Pharm Sin B20177326028028540164
- WeissigVPettingerTKMurdockNNanopharmaceuticals (part 1): products on the marketInt J Nanomedicine201494357437325258527
- NguyenVHLeeBJProtein corona: a new approach for nanomedicine designInt J Nanomedicine2017123137315128458536
- YangLKuangHZhangWAguilarZPWeiHXuHComparisons of the biodistribution and toxicological examinations after repeated intravenous administration of silver and gold nanoparticles in miceSci Rep201771330328607366
- HuhYSmithDEFengMRInterspecies scaling and prediction of human clearance: comparison of small- and macro-molecule drugsXenobiotica2011411197298721892879