References
- IttrichHPeldschusKRaabeNKaulMAdamGSuperparamagnetic iron oxide nanoparticles in biomedicine: applications and developments in diagnostics and therapyFortschr Röntgenstr20131851211491166
- WeinsteinJSVarallyayCGDosaESuperparamagnetic iron oxide nanoparticles: diagnostic magnetic resonance imaging and potential therapeutic applications in neurooncology and central nervous system inflammatory pathologies, a reviewJ Cereb Blood Flow Metab2010301153519756021
- BusquetsMAEspargaróASabatéREstelrichJMagnetic nanoparticles cross the blood-brain barrier: when physics rises to a challengeNanomaterials2015542231224828347118
- HammBStaksTTaupitzMContrast-enhanced MR imaging of liver and spleen: first experience in humans with a new superparamagnetic iron oxideJ Magn Reson Imaging1994456596687981510
- WangJChenYChenBPharmacokinetic parameters and tissue distribution of magnetic Fe(3)O(4) nanoparticles in miceInt J Nanomedicine2010586186621042548
- WangBFengWYWangMTransport of intranasally instilled fine Fe2O3 particles into the brain: micro-distribution, chemical states, and histopathological observationBiol Trace Elem Res2007118323324317916926
- WuJDingTSunJNeurotoxic potential of iron oxide nanoparticles in the rat brain striatum and hippocampusNeurotoxicology20133424325322995439
- GuptaNShyamasundarSPatnalaRRecent progress in therapeutic strategies for microglia-mediated neuroinflammation in neuropathologiesExpert Opin Ther Targets201822976578130138572
- WangYWangBZhuMTMicroglial activation, recruitment and phagocytosis as linked phenomena in ferric oxide nanoparticle exposureToxicol Lett20112051263721596115
- DhakshinamoorthyVManickamVPerumalENeurobehavioural toxicity of iron oxide nanoparticles in miceNeurotox Res201732218720328321581
- XueYWuJSunJFour types of inorganic nanoparticles stimulate the inflammatory reaction in brain microglia and damage neurons in vitroToxicol Lett20122142919822939914
- PettersCThielKDringenRLysosomal iron liberation is responsible for the vulnerability of brain microglial cells to iron oxide nanoparticles: comparison with neurons and astrocytesNanotoxicology201610333234226287375
- WuHYChungMCWangCCHuangCHLiangHJJanTRIron oxide nanoparticles suppress the production of IL-1beta via the secretory lysosomal pathway in murine microglial cellsPart Fibre Toxicol2013104624047432
- ConstantinescuCSFarooqiNO’BrienKGranBExperimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)Br J Pharmacol201116441079110621371012
- MurphyACLalorSJLynchMAMillsKHGInfiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitisBrain Behav Immun201024464165120138983
- LegrouxLArbourNMultiple sclerosis and T lymphocytes: an entangled storyJ Neuroimmune Pharmacol201510452854625946987
- MillwardJMSchnorrJTaupitzMWagnerSWuerfelJTInfante-DuarteCIron oxide magnetic nanoparticles highlight early involvement of the choroid plexus in central nervous system inflammationASN Neuro201352e00110 AN2012008123452162
- KirschbaumKSonnerJKZellerMWIn vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosisProc Natl Acad Sci U S A201611346132271323227799546
- DoussetVBrochetBDeloireMSMR imaging of relapsing multiple sclerosis patients using ultra-small-particle iron oxide and compared with gadoliniumAJNR Am J Neuroradiol20062751000100516687532
- TothGBVarallyayCGHorvathACurrent and potential imaging applications of ferumoxytol for magnetic resonance imagingKidney Int2017921476628434822
- ShenCCLiangHJWangCCLiaoMHJanTRA role of cellular glutathione in the differential effects of iron oxide nanoparticles on antigen-specific T cell cytokine expressionInt J Nanomedicine201162791279822114506
- WangJChenFZhengPHuperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression of T cell-mediated neuronal inflammation in miceExp Neurol20122361798722524989
- ScuteriADonzelliERigolioRTherapeutic administration of mesenchymal stem cells abrogates the relapse phase in chronic relapsing-remitting EAEJ Stem Cell Res Ther201552262
- ShenCCWangCCLiaoMHJanTRA single exposure to iron oxide nanoparticles attenuates antigen-specific antibody production and T-cell reactivity in ovalbumin-sensitized BALB/c miceInt J Nanomedicine201161229123521753874
- SadeghiLBabadiVYEspananiHRToxic effects of the Fe2O3 nanoparticles on the liver and lung tissueBratislava Medical Journal20151160637337826084739
- LassmannHMultiple sclerosis pathologyCold Spring Harb Perspect Med201883a02893629358320
- LuoCJianCLiaoYThe role of microglia in multiple sclerosisNeuropsychiatr Dis Treat2017131661166728721047
- JägerADardalhonVSobelRABettelliEKuchrooVKTh1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypesJ Immunol2009183117169717719890056
- BrahmachariSPahanKRole of cytokine p40 family in multiple sclerosisMinerva Med200899210511818431321
- LimHXHongHJJungMYChoDKimTSPrincipal role of IL-12p40 in the decreased Th1 and Th17 responses driven by dendritic cells of mice lacking IL-12 and IL-18Cytokine201363217918623697689
- GuoWWangCWangXA novel human truncated IL12rβ1-Fc fusion protein ameliorates experimental autoimmune encephalomyelitis via specific binding of p40 to inhibit Th1 and Th17 cell differentiationOncotarget2015630285392855526384304
- ParkEJOhSYKimYDistribution and immunotoxicity by intravenous injection of iron nanoparticles in a murine modelJ Appl Toxicol201636341442326416317
- WangBFengWZhuMNeurotoxicity of low-dose repeatedly intranasal instillation of nano- and submicron-sized ferric oxide particles in miceJournal of Nanoparticle Research20091114153
- YarjanliZGhaediKEsmaeiliARahgozarSZarrabiAIron oxide nanoparticles may damage to the neural tissue through iron accumulation, oxidative stress, and protein aggregationBMC Neurosci20171815128651647
- SripetchwandeeJPipatpiboonNChattipakornNChattipakornSCombined therapy of iron chelator and antioxidant completely restores brain dysfunction induced by iron toxicityPLoS One201491e8511524400127
- SchneiderSANeurodegeneration with brain iron accumulationCurr Neurol Neurosci Rep2016161926739693
- WángYXIdéeJMA comprehensive literatures update of clinical researches of superparamagnetic resonance iron oxide nanoparticles for magnetic resonance imagingQuant Imaging Med Surg2017718812228275562
- MaaroufAFerréJCZaaraouiWUltra-small superparamagnetic iron oxide enhancement is associated with higher loss of brain tissue structure in clinically isolated syndromeMult Scler20162281032103926453679
- RodgersJMMillerSDCytokine control of inflammation and repair in the pathology of multiple sclerosisYale J Biol Med201285444746823239947
- ZhuMTWangBWangYEndothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: risk factors for early atherosclerosisToxicol Lett2011203216217121439359
- Mulens-AriasVRojasJMPérez-YagüeSMoralesMPBarberDFPolyethylenimine-coated SPIONs trigger macrophage activation through TLR-4 signaling and ROS production and modulate podosome dynamicsBiomaterials20155249450625818455
- ChenBAJinNWangJThe effect of magnetic nanoparticles of Fe3O4 on immune function in normal ICR miceInt J Nanomedicine2010559359920856834
- ParkEJOhSYLeeSJChronic pulmonary accumulation of iron oxide nanoparticles induced Th1-type immune response stimulating the function of antigen-presenting cellsEnviron Res2015143Pt A13814726492398
- ZhuMTianXSongXNanoparticle-induced exosomes target antigen-presenting cells to initiate Th1-type immune activationSmall20128182841284822674628