288
Views
26
CrossRef citations to date
0
Altmetric
Original Research

Strategic approach to developing a self-microemulsifying drug delivery system to enhance antiplatelet activity and bioavailability of ticagrelor

, , , , , , , , , & show all
Pages 1193-1212 | Published online: 15 Feb 2019

References

  • HustedSEmanuelssonHHeptinstallSSandsetPMWickensMPetersGPharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: a double-blind comparison to clopidogrel with aspirinEur Heart J20062791038104716476694
  • TengROliverSHayesMAButlerKAbsorption, distribution, metabolism, and excretion of ticagrelor in healthy subjectsDrug Metab Dispos20103891514152120551239
  • van GiezenJJHumphriesRGPreclinical and clinical studies with selective reversible direct P2Y12 antagonistsSemin Thromb Hemost2005310219520415852223
  • HustedSvan GiezenJJJTicagrelor: the first reversibly binding oral P2Y12 receptor antagonistCardiovas Ther2009274259274
  • WijeyeratneYDJoshiRHeptinstallSTicagrelor: a P2Y12 antagonist for use in acute coronary syndromesExpert Rev Clin Pharmacol20125325726922697589
  • WallentinLBeckerRCBudajATicagrelor versus clopidogrel in patients with acute coronary syndromesN Engl J Med2009361111045105719717846
  • BRILINTA (ticagrelor) [package insert]Wilmington, DEAstraZeneca Pharmaceuticals LP2016
  • RameshKShekarCKhadgapathiPEnhancement of solubility and rate of in vitro drug release profiles of poorly soluble ticagrelor by solvent evaporation solid dispersion techniqueIndo Am J Pharm Res201551238503858
  • PaiGSathyanarayanaMBFabrication and solid state characterization of ticagrelor co-crystals with improved solubility and dissolutionInt J Pharm Qual Assur20178118
  • ChenZQLiuYZhaoJHWangLFengNPImproved oral bioavailability of poorly water-soluble indirubin by a supersaturatable self-micro-emulsifying drug delivery systemInt J Nanomedicine201271115112522403491
  • KambojSSharmaRSinghKRanaVAprepitant loaded solid pre-concentrated microemulsion for enhanced bioavailability: a comparison with micronized aprepitantEur J Pharm Sci2015789010226165621
  • YeomDWSongYSKimSRDevelopment and optimization of a self-microemulsifying drug delivery system for atorvastatin calcium by using D-optimal mixture designInt J Nanomedicine2015103865387826089663
  • YeomDWChaeBRSonHYEnhanced oral bioavailability of valsartan using a polymer-based supersaturable self-microemulsifying drug delivery systemInt J Nanomedicine2017123533354528507434
  • PatelGShelatPLalwaniAStatistical modeling, optimization and characterization of solid self-nanoemulsifying drug delivery system of lopinavir using design of experimentDrug Deliv20162383027304226882014
  • KambojSRanaVQuality-by-design based development of a self-microemulsifying drug delivery system to reduce the effect of food on nelfinavir mesylateInt J Pharm20165011–231132526854426
  • ElnaggarYSEl-MassikMAAbdallahOYSelf-nanoemulsifying drug delivery systems of tamoxifen citrate: design and optimizationInt J Pharm20093801–213314119635537
  • PorterCJPoutonCWCuineJFCharmanWNEnhancing intestinal drug solubilisation using lipid-based delivery systemsAdv Drug Deliv Rev200860667369118155801
  • PorterCJHCharmanWNIn vitro assessment of oral lipid based formulationsAdv Drug Deliv Rev200150Suppl 1S127S14711576699
  • BalakrishnanPLeeBJOhDHEnhanced oral bioavailability of coenzyme Q10 by self-emulsifying drug delivery systemsInt J Pharm20093741–2667219446761
  • DixitARRajputSJPatelSGPreparation and bioavailability assessment of SMEDDS containing valsartanAAPS Pharm Sci Tech2010111314321
  • KrishnamoorthyBHabibur RahmanSMTamil SelvanNDesign, formulation, in vitro, in vivo, and pharmacokinetic evaluation of nisoldipine-loaded self-nanoemulsifying drug delivery systemJ Nanopart Res201517134
  • BuenoLMManoelJWGiordaniCFHPLC method for simultaneous analysis of ticagrelor and its organic impurities and identification of two major photodegradation productsEur J Pharm Sci201797222927816632
  • PoutonCWFormulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification systemEur J Pharm Sci2006293–427828716815001
  • SchefféHExperiments with mixturesJ R Stat Soc Series B1958202344360
  • GurramAKDeshpandePBKarSSNayakUYUdupaNReddyMSRole of components in the formation of self-microemulsifying drug delivery systemsIndian J Pharm Sci201577324925726180269
  • HallSPacekAWKowalskiAJCookeMRothmanDThe effect of scale and interfacial tension on liquid–liquid dispersion in in-line Silverson rotor–stator mixersChem Eng Res Des2013911121562168
  • LuYParkKPolymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugsInt J Pharm2013453119821422944304
  • JaiswalPAggarwalGHarikumarSLSinghKDevelopment of self-microemulsifying drug delivery system and solid-self-microemulsifying drug delivery system of telmisartanInt J Pharm Investig201444195206
  • AkulaSGurramAKDevireddySRSelf-microemulsifying drug delivery systems: an attractive strategy for enhanced therapeutic profileInt Sch Res Notices2014201496405127382619
  • XuWLingPZhangTPolymeric micelles, a promising drug delivery system to enhance bioavailability of poorly water-soluble drugsJ Drug Deliv2013201334031523936656
  • McshaneBBGalDStatistical significance and the dichotomization of evidenceJ Am Stat Assoc2017112519885895
  • MourabetMEl RhilassiAEl BoujaadyHBennani-ZiatniMTaitaiAUse of response surface methodology for optimization of fluoride adsorption in an aqueous solution by BrushiteArab J Chem201710S3292S3302
  • SchneiderAAHommelGBlettnerMLinear regression analysis: part 14 of a series on evaluation of scientific publicationsDtsch Ärztebl Int20101074477678221116397
  • BewickVCheekLBallJStatistics review 7: correlation and regressionCrit Care20037645145914624685
  • PatelDVPreparation and evaluation of extended release pellets of chiral molecules of s-metoprolol succinate by different technologyAsian J Pharm2017113210223
  • Figueiredo FilhoDBSilva JúniorJARochaECWhat is R2 all about?Leviathan2011336068
  • BalataGFEssaEAShamardlHAZaidanSHAbourehabMASelf-emulsifying drug delivery systems as a tool to improve solubility and bioavailability of resveratrolDrug Des Devel Ther201610117128
  • ZhouHWanJWuLA new strategy for enhancing the oral bioavailability of drugs with poor water-solubility and low liposolubility based on phospholipid complex and supersaturated SEDDSPLoS One2013812e8453024391965
  • PatelDSawantKSelf micro-emulsifying drug delivery system: formulation development and biopharmaceutical evaluation of lipophilic drugsCurr Drug Deliv20096441942419534704
  • TahaEIAl-SaidanSSamyAMKhanMAPreparation and in vitro characterization of self-nanoemulsified drug delivery system (SNEDDS) of all-trans-retinol acetateInt J Pharm20042851–210911915488684
  • NekkantiVKaratgiPPrabhuRPillaiRSolid self-microemulsifying formulation for candesartan cilexetilAAPS PharmSciTech201011191720013081
  • MemvangaPBEloyPGaigneauxEMPréatVIn vitro lipolysis and intestinal transport of β-arteether-loaded lipid-based drug delivery systemsPharm Res201330102694270523739990
  • EdwardsCMMayJAHeptinstallSLoweKCEffects of pluronic F-68 (poloxamer 188) on platelet aggregation in human whole bloodThromb Res19968145115128907302