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Original Research

Di-O-lauroyl-decitabine-lipid nanocapsules: toward extending decitabine activity

, , , , , , , & show all
Pages 2091-2102 | Published online: 26 Mar 2019

References

  • Rodriguez-AbreuDBordoniAZuccaEEpidemiology of hematological malignanciesAnn Oncol200718Suppl 1i3i817311819
  • VisserOTramaAMaynadiéMIncidence, survival and prevalence of myeloid malignancies in EuropeEur J Cancer201248173257326622770878
  • DöhnerHEsteyEHAmadoriSDiagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNetBlood2010115345347419880497
  • ShahAAnderssonTM-LRachetBBjörkholmMLambertPCSurvival and cure of acute myeloid leukaemia in England, 1971–2006: a population-based studyBr J Haematol2013162450951623786647
  • LuLJRanderathKLong term instability and molecular mechanism of 5-azacytidine-induced DNA hypomethylation in normal and neoplastic tissues in vivoMol Pharmacol19842635946036208475
  • StresemannCLykoFModes of action of the DNA Methyltransferase inhibitors azacytidine and decitabineInt J Cancer2008123181318425818
  • KarahocaMMomparlerRLPharmacokinetic and pharmacodynamic analysis of 5-aza-2′-deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapyClin Epigenetics201351323369223
  • BlumWGarzonRKlisovicRBClinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabineProc Natl Acad Sci2010107167473747820368434
  • LancetJECortesJEHoggeDEPhase 2 trial of CPX-351, a fixed 5:1 molar ratio of cytarabine/daunorubicin, vs cytarabine/daunorubicin in older adults with untreated AMLBlood2014123213239324624687088
  • LancetJEUyGLCortesJEFinal results of a phase III randomized trial of CPX-351 versus 7+3 in older patients with newly diagnosed high risk (secondary) AMLJ Clin Oncol20163415_suppl70007000
  • GriffithsEAChoyGRedkarSTavernaPAzabMKarpfARSGI-110: DNA methyltransferase inhibitor oncolyticDrugs Future201338853554326190889
  • VijayaraghavaluSLabhasetwarVEfficacy of decitabine-loaded nanogels in overcoming cancer drug resistance is mediated via sustained DNA methyltransferase 1 (DNMT1) depletionCancer Lett2013331112212923305699
  • HeurtaultBSaulnierPPechBProustJ-EBenoitJ-PA novel phase inversion-based process for the preparation of lipid nanocarriersPharm Res200219687588012134960
  • HuynhNTPassiraniCSaulnierPBenoitJPLipid nanocapsules: a new platform for nanomedicineInt J Pharm2009379220120919409468
  • LagarceFPassiraniCNucleic-acid delivery using lipid nanocapsulesCurr Pharm Biotechnol201617872372727033510
  • HureauxJLagarceFGagnadouxFToxicological study and efficacy of blank and paclitaxel-loaded lipid nanocapsules after i.v. administration in micePharm Res201027342143020054705
  • HureauxJLacoeuilleFLagarceFAbsence of lung fibrosis after a single pulmonary delivery of lipid nanocapsules in ratsInt J Nanomedicine2017128159817029184405
  • ThomasOLagarceFLipid nanocapsules: a nanocarrier suitable for scale-up processJ Drug Delivery Sci Technol2013236555559
  • BriotTRogerELautramNVergerAClavreulALagarceFDevelopment and in vitro evaluations of new decitabine nanocarriers for the treatment of acute myeloid leukemiaInt J Nanomedicine2017128427844229200853
  • KantarjianHMThomasXGDmoszynskaAMulticenter, ran-domized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemiaJCO2012302126702677
  • LinKTMomparlerRLRivardGEHigh-performance liquid chromatographic analysis of chemical stability of 5-aza-2′-deoxycytidineJ Pharm Sci19817011122812326170748
  • TománkováHZýkaJStudy of the time dependence of the stability of 5-aza-2′-deoxycytidine in acid mediumMicrochem J 1980/09/01/1980253281288
  • Kim SunHHeeb RitaMKrämerIPhysicochemical stability of reconstituted decitabine (Dacogen®) solutions and ready-to-administer infusion bags when stored refrigerated or frozenPharmaceutical Technology in Hospital Pharmacy22017145
  • HureauxJLagarceFGagnadouxFLipid nanocapsules: ready-to-use nanovectors for the aerosol delivery of paclitaxelEur J Pharm Biopharm200973223924619560538
  • MoysanEBastiatGBenoitJ-PGemcitabine versus modified gemcitabine: a review of several promising chemical modificationsMol Pharm201310243044422978251
  • BergmanAMKuiperCMVoornDAAntiproliferative activity and mechanism of action of fatty acid derivatives of arabinofuranosyl-cytosine in leukemia and solid tumor cell linesBiochem Pharmacol200467350351115037202
  • BergmanAMAdemaADBalzariniJAntiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor modelsInvest New Drugs201129345646620066470
  • QinTJelinekJSiJShuJIssaJ-PJMechanisms of resistance to 5-aza-2′-deoxycytidine in human cancer cell linesBlood2009113365966718931345
  • IssaJ-PJRobozGRizzieriDSafety and tolerability of guadecitabine (SGI-110) in patients with myelodysplastic syndrome and acute myeloid leukaemia: a multicentre, randomised, dose-escalation phase 1 studyLancet Oncol20151691099111026296954
  • SaliouBThomasOLautramNDevelopment and in vitro evaluation of a novel lipid nanocapsule formulation of etoposideEur J Pharm Sci201350217218023831519
  • RogerELagarceFBenoitJ-PDevelopment and characterization of a novel lipid nanocapsule formulation of SN38 for oral administrationEur J Pharm Biopharm201179118118821303693
  • NeupaneYRSrivastavaMAhmadNKumarNBhatnagarAKohliKLipid based nanocarrier system for the potential oral delivery of decitabine: formulation design, characterization, ex vivo, and in vivo assessmentInt J Pharm20144771–260161225445972
  • DulieuCBazileDInfluence of lipid nanocapsules composition on their aptness to freeze-dryingPharm Res200522228529215783077
  • TaoWZhaoDSunMIntestinal absorption and activation of decitabine amino acid ester prodrugs mediated by peptide transporter PEPT1 and enterocyte enzymesInt J Pharm20185411–2647129471144
  • ZhangYSunJGaoYA carrier-mediated prodrug approach to improve the oral absorption of antileukemic drug decitabineMol Pharm20131083195320223822717
  • ClouserCLBonnacLManskyLMPattersonSECharacterization of permeability, stability and anti-HIV-1 activity of decitabine and gemcitabine divalerate prodrugsAntivir Chem Chemother201423622323023994876
  • Garcia-ManeroGOdenikeOAmreinPCSuccessful emulation of IV decitabine pharmacokinetics with an oral Fixed-dose combination of the oral cytidine deaminase inhibitor (CDAi) E7727 with oral decitabine, in subjects with myelodysplastic syndromes (MDS): final data of phase 1 studyAm Soc Hematology2016
  • LavelleDVaitkusKLingYEffects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabineBlood201211951240124722160381
  • SloatBRSandovalMALiDIn vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticlesInt J Pharm20114091–227828821371545
  • LainéA-LClavreulaRousseauaInhibition of ectopic glioma tumor growth by a potent ferrocenyl drug loaded into stealth lipid nanocapsulesNanomedicine20141081667167724842766
  • PaillardAHindréFVignes-ColombeixCBenoitJ-PGarcionEThe importance of endo-lysosomal escape with lipid nanocapsules for drug subcellular bioavailabilityBiomaterials201031297542755420630585
  • HollenbachPWNguyenANBradyHA comparison of azaciti-dine and decitabine activities in acute myeloid leukemia cell linesPLoS One201052e900120126405
  • VijayaraghavaluSDermawanJKCheriyathVLabhasetwarVHighly synergistic effect of sequential treatment with epigenetic and anticancer drugs to overcome drug resistance in breast cancer cells is mediated via activation of p21 gene expression leading to G2/M cycle arrestMol Pharm201310133735223215027
  • ThépotSLaineyECluzeauTHypomethylating agents reactivate FOXO3a in acute myeloid leukemiaCell Cycle201110142323233021654193
  • LiuZMarcucciGByrdJCGreverMXiaoJChanKKCharac-terization of decomposition products and preclinical and low dose clinical pharmacokinetics of decitabine (5-aza-2′-deoxycytidine) by a new liquid chromatography/tandem mass spectrometry quantification methodRapid Commun Mass Spectrom20062071117112616523529
  • XuHLvSQiaoMDevelopment and validation of a liquid chromatography–tandem mass spectrometry method for quantification of decitabine in rat plasmaJournal of Chromatography B20128998185
  • SassoMSLolloGPitorreMLow dose gemcitabine-loaded lipid nanocapsules target monocytic myeloid-derived suppressor cells and potentiate cancer immunotherapyBiomaterials201696476227135716
  • LainéA-LGravierJHenryMConventional versus stealth lipid nanoparticles: formulation and in vivo fate prediction through FRET monitoringJ Control Release20141881824878182
  • GrooACBossiereMTrichardLLegrasPBenoitJPLagarceFIn vivo evaluation of paclitaxel-loaded lipid nanocapsules after intravenous and oral administration on resistant tumorNanomedicine201510458960125723092