Ultra-small gadolinium oxide nanocrystal sensitization of non-small-cell lung cancer cells toward X-ray irradiation by promoting cytostatic autophagy

References

• BrayFFerlayJSoerjomataramISiegelRLTorreLAJemalAGlobal Cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countriesCA Cancer J Clin201868639442430207593
   PubMed Web of Science ®Google Scholar
• CaoCD’AmicoTDemmyTSurgery versus SABR for resectable non-small-cell lung cancerLancet Oncol2015168e370e37126248836
   PubMedGoogle Scholar
• ElsayadKSamhouriLScobioalaSHaverkampUEichHTIs tumor volume reduction during radiotherapy prognostic relevant in patients with stage III non-small cell lung cancer?J Cancer Res Clin Oncol201814461165117129623466
   PubMed Web of Science ®Google Scholar
• NiederCde RuysscherDGasparLEReirradiation of recurrent node-positive non-small cell lung cancer after previous stereotactic radiotherapy for stage I diseaseStrahlenther Onkol2017193751552428424839
   PubMedGoogle Scholar
• ZhuZ-FMaHLFanMSequential chemoradiotherapy with accelerated hypofractionated radiotherapy compared to concurrent chemoradiotherapy with standard radiotherapy for locally advanced non-small cell lung cancerTechnol Cancer Res Treat201413326927524066952
   PubMedGoogle Scholar
• RamrothJCutterDJDarbySCDose and fractionation in radiation therapy of curative intent for non-small cell lung cancer: meta-analysis of randomized trialsInt J Radiat Oncol Biol Phys201696473674727639294
   PubMed Web of Science ®Google Scholar
• KimJPiaoYHyeonTMultifunctional nanostructured materials for multimodal imaging, and simultaneous imaging and therapyChem Soc Rev200938237239019169455
   PubMed Web of Science ®Google Scholar
• AhmadRRoyleGLourençoASchwarzMFracchiollaFRickettsKInvestigation into the effects of high-Z nano materials in proton therapyPhys Med Biol201661124537455027224304
   PubMedGoogle Scholar
• KuncicZLacombeSNanoparticle radio-enhancement: principles, progress and application to cancer treatmentPhys Med Biol201863202TR01
   PubMedGoogle Scholar
• LiuYZhangPLiFMetal-based NanoEnhancers for Future Radiotherapy: Radiosensitizing and Synergistic Effects on Tumor CellsTheranostics2018871824184929556359
   PubMed Web of Science ®Google Scholar
• CuiLHerSBorstGRBristowRGJaffrayDAAllenCRadiosensitization by gold nanoparticles: will they ever make it to the clinic?Radiother Oncol2017124334435628784439
   PubMed Web of Science ®Google Scholar
• HerSJaffrayDAAllenCGold nanoparticles for applications in cancer radiotherapy: mechanisms and recent advancementsAdv Drug Deliv Rev20171098410126712711
   PubMed Web of Science ®Google Scholar
• KotbSDetappeALuxFGadolinium-based nanoparticles and radiation therapy for multiple brain melanoma metastases: proof of concept before phase I trialTheranostics20166341842726909115
   PubMed Web of Science ®Google Scholar
• LuxFVerryCDufortSTillementOLe DucGBalossoJUltrasmall theranostic nanoparticles for the treatment of multiple brain metastases by radiation therapy: a first in manInt J Radiat Oncol Biol Phys2017992SupplE34
   Google Scholar
• Le DucGMiladiIAlricCToward an image-guided microbeam radiation therapy using gadolinium-based nanoparticlesACS Nano20115129566957422040385
   PubMed Web of Science ®Google Scholar
• DufortSBianchiAHenryMNebulized gadolinium-based nanoparticles: a theranostic approach for lung tumor imaging and radiosensitizationSmall201511221522125201285
   PubMedGoogle Scholar
• ParkJYBaekMJChoiESParamagnetic ultrasmall gadolinium oxide nanoparticles as advanced T1 MRI contrast agent: account for large longitudinal relaxivity, optimal particle diameter, and in vivo T1 MR imagesACS Nano20093113663366919835389
   PubMed Web of Science ®Google Scholar
• AhrénMSelegårdLKlassonASynthesis and characterization of PEGylated Gd2O3 nanoparticles for MRI contrast enhancementLangmuir20102685753576220334417
   PubMed Web of Science ®Google Scholar
• MaX-HGongAXiangLCBiocompatible composite nanoparticles with large longitudinal relaxivity for targeted imaging and early diagnosis of cancerJ Mater Chem B201312734193428
   PubMedGoogle Scholar
• FaucherLTremblayMLagueuxJGossuinYFortinMARapid synthesis of PEGylated ultrasmall gadolinium oxide nanoparticles for cell labeling and tracking with MRIACS Appl Mater Interfaces2012494506451522834680
   PubMed Web of Science ®Google Scholar
• AmirrashediMAlamNRMostaaraSHaghgooSGorjiEJaberiRDose enhancement in radiotherapy by novel application of gadolinium based MRI contrast agent Nanomagnetic particles in gel dosimetryIfmbe Proc201551816822
   Google Scholar
• SeoSJHanSMChoJHEnhanced production of reactive oxygen species by gadolinium oxide nanoparticles under core-inner-shell excitation by proton or monochromatic X-ray irradiation: implication of the contribution from the interatomic de-excitation-mediated nano-radiator effect to dose enhancementRadiat Environ Biophys201554442343126242374
   PubMedGoogle Scholar
• LiuYLiuXJinXThe dependence of radiation enhancement effect on the concentration of gold nanoparticles exposed to low- and high-LET radiationsPhys Med201531321021825651760
   PubMedGoogle Scholar
• LiuXLiuYJinXRadiosensitizing effect of functionalized gold nanoparticles on human hepatoma HepG2 cellsNanomedicine2016122546
   Google Scholar
• LiuYLiuXZhangPThe synergistic radiosensitizing effect of tirapazamine-conjugated gold nanoparticles on human hepatoma HepG2 cells under X-ray irradiationInt J Nanomed20161135173531
   PubMedGoogle Scholar
• SöderlindFPedersenHPetoralRMKällP-OUvdalKSynthesis and characterisation of Gd2O3 nanocrystals functionalised by organic acidsJ Colloid Interface Sci2005288114014815927572
   PubMedGoogle Scholar
• LiuYLiuXJinXThe radiation enhancement of 15 nm Citrate-Capped gold nanoparticles exposed to 70 keV/µm carbon ionsJ Nanosci Nanotechnol20161632365237027455642
   PubMedGoogle Scholar
• LiFZhengXLiuYDifferent roles of CHOP and JNK in mediating radiation-induced autophagy and apoptosis in breast cancer cellsRadiat Res2016185553954827135967
   PubMed Web of Science ®Google Scholar
• WenYZhangWGongNCarrier-free, self-assembled pure drug nanorods composed of 10-hydroxycamptothecin and chlorin e6 for combinatorial chemo-photodynamic antitumor therapy in vivoNanoscale2017938143471435628731112
   PubMedGoogle Scholar
• ArandaASequedoLTolosaLDichloro-dihydro-fluorescein diacetate (DCFH-DA) assay: a quantitative method for oxidative stress assessment of nanoparticle-treated cellsToxicol In Vitro201327295496323357416
   PubMed Web of Science ®Google Scholar
• PougetJPMatherSJGeneral aspects of the cellular response to low-and high-LET radiationEur J Nucl Med200128454156111357507
   PubMedGoogle Scholar
• VandersickelVDepuydtJvan BockstaeleBEarly increase of radiation-induced γH2AX foci in a human Ku70/80 knockdown cell line characterized by an enhanced radiosensitivityJ Radiat Res201051663364121116096
   PubMedGoogle Scholar
• KriegsMCanYBrammerIRadiosensitization of NSCLC cells by EGFR inhibition is the result of an enhanced p53-dependent G1 arrestStrahlenther Onkol2015191S82
   Google Scholar
• JinXLiuYYeFRole of autophagy in high linear energy transfer radiation-induced cytotoxicity to tumor cellsCancer Sci2014105777077824731006
   PubMedGoogle Scholar
• ChaachouayHOhneseitPToulanyMKehlbachRMulthoffGRodemannHPAutophagy contributes to resistance of tumor cells to ionizing radiationRadiother Oncol201199328729221722986
   PubMed Web of Science ®Google Scholar
• KlionskyDJAbdallaFCAbeliovichHGuidelines for the use and interpretation of assays for monitoring autophagyAutophagy20128444554422966490
   PubMed Web of Science ®Google Scholar
• ChenSRehmanSKZhangWWenAYaoLZhangJAutophagy is a therapeutic target in anticancer drug resistanceBiochim Biophys Acta20101806222022920637264
   PubMed Web of Science ®Google Scholar
• StefančíkováLPorcelEEustachePCell localisation of gadolinium-based nanoparticles and related radiosensitising efficacy in glioblastoma cellsCancer Nanotechnol201451625328549
   PubMedGoogle Scholar
• YasuiHTakeuchiRNaganeMRadiosensitization of tumor cells through endoplasmic reticulum stress induced by PEGylated nanogel containing gold nanoparticlesCancer Lett2014347115115824530512
   PubMed Web of Science ®Google Scholar
• SonnenblickBPNeotetrazolium as a visible indicator of radiation damage – reaction of allium cytoplasm to X-radiationGenetics1953386692693
   Google Scholar
• JinXLiFLiuBDifferent mitochondrial fragmentation after irradiation with X-rays and carbon ions in HeLa cells and its influence on cellular apoptosisBiochem Biophys Res Commun2018500495896529709476
   PubMed Web of Science ®Google Scholar
• BhatPKrielJShubha PriyaBShubha PriyaBShivananjuNSLoosBModulating autophagy in cancer therapy: advancements and challenges for cancer cell death sensitizationBiochem Pharmacol201814717018229203368
   PubMed Web of Science ®Google Scholar
• KroemerGLevineBAutophagic cell death: the story of a misnomerNat Rev Mol Cell Biol20089121004101018971948
   PubMed Web of Science ®Google Scholar
• ApelAHerrISchwarzHRodemannHPMayerABlocked autophagy sensitizes resistant carcinoma cells to radiation therapyCancer Res20086851485149418316613
   PubMed Web of Science ®Google Scholar
• ZabirnykOYezhelyevMSeleverstovONanoparticles as a novel class of autophagy activatorsAutophagy20073327828117351332
   PubMed Web of Science ®Google Scholar
• WuHLinJLiuPReactive oxygen species acts as executor in radiation enhancement and autophagy inducing by AgNPsBiomaterials20161011927254247
   PubMed Web of Science ®Google Scholar
• GewirtzDAHillikerMLWilsonENPromotion of autophagy as a mechanism for radiation sensitization of breast tumor cellsRadiother Oncol200992332332819541381
   PubMedGoogle Scholar
• AntoniaSJVillegasADanielDDurvalumab after chemoradiotherapy in stage III non-small-cell lung cancerN Engl J Med2017377201919192928885881
   PubMed Web of Science ®Google Scholar