References
- OzolsRFHerbstRSColsonYLClinical cancer advances 2006: major research advances in cancer treatment, prevention, and screening – a report from the American Society of Clinical OncologyJ Clin Oncol20072514616217158528
- HubbellJAMaterials science: enhancing drug functionScience200330059559612714733
- CaiCZhouKWuYWuLEnhanced liver targeting of 5-fluorouracil using galactosylated human serum albumin as a carrier moleculeJ Drug Target200614556116608732
- CaoSRustumYMSynergistic antitumor activity of irinotecan in combination with 5-fluorouracil in rats bearing advanced colorectal cancer: role of drug sequence and doseCancer Res2000603717372110919639
- KubotaTRecent progress in combination therapy of low-dose CDDP/5-FU in Japan. Theoretical basis for low-dose CDDP/5-FU therapyJpn J Cancer Chemother19992615361541
- ShapiroWRGreenSBBurgerPCA randomized comparison of intra-arterial versus intravenous with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant gliomaJ Neurosurg1992767727811564540
- HutchinsLFGreenSJRavdinPMRandomized, controlled trial of cyclophosphamide, methotrexate, and fluorouracil versus cyclophosphamide, doxorubicin, and fluorouracil with and without tamoxifen for high-risk, node-negative breast cancer: treatment results of Intergroup Protocol INT-0102J Clin Oncol2005238313832116293862
- LongleyDBHarkinDPJohnstonPG5-fluorouracil: mechanisms of action and clinical strategiesNat Rev Cancer2003333033812724731
- ParkerWBChengYCMetabolism and mechanism of action of 5-fluorouracilPharmacol Ther1990483813951707544
- FataFRonIGKemenyNO’ReillyEKlimstraDKelsenDP5-fluorouracil-induced small bowel toxicity in patients with colorectal carcinomaCancer2000861129113410506695
- PaoloADDanesiRFalconeARelationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patientsAnn Oncol2001121301130611697844
- van KuilenburgABPHaasjesJRichelDJClinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD geneClin Cancer Res200064705471211156223
- Boisdron-CelleMMeneiPHBenoitJPPreparation and characterization of 5-fluorouracil-loaded microparticles as biodegradable anticancer drug carriersJ Pharm Pharmacol1995471087602463
- ChoSHLeeHBPreparation of 5-fluorouracil-loaded poly (L-lactide-co-glycolide) wafer and evaluation of in vitro release behaviorMacromolecular Res200311183188
- WangGTuckerIGRobertsMSHirstLWIn vitro and in vivo evaluation in rabbits of a controlled release 5-fluorouracil subconjunctival implant based on poly (D, L-lactide-co-glycolide)Pharm Res199613105910648842045
- LeeJSChaeGSKimbMSChoSHLeeHBKhangGDegradation behaviour in vitro for poly (D, L-lactide-co-glycolide) as drug carrierBiomed Mater Eng20041418519215156109
- MakinoKNakajimaTShikamuraMEfficient intracellular delivery of rifampicin to alveolar macrophages using rifampicin-loaded PLGA microspheres: effects of molecular weight and composition of PLGA on release of rifampicinColloids Surf B Biointerfaces200436354215261021
- YooJYKimJMKhangGEffect of lactide/glycolide monomers on release behaviors of gentamicin sulfate-loaded PLGA discsInt J Pharm20042761915113609
- LemaireLRoullinVGFranconiFTherapeutic efficacy of 5-fluorouracil-loaded microspheres on rat glioma: a magnetic resonance imaging studyNMR Biomed20011436036611599034
- MeneiPBoisdron-CelleMCrouéAGuyGBenoitJPEffect of stereotactic implantation of biodegradable 5-fluorouracil-loaded microspheres in healthy and C6 glioma-bearing ratsNeurosurgery1996391171238805147
- MeneiPVenierMCGamelinELocal and sustained delivery of 5 fluorouracil from biodegradable microspheres for the radiosensitization of glioblastomaCancer19998632533010421269
- KimJHKimYSParkKAntitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing miceJ Control Release2008127414918234388
- UpadhyayKKBhattANMishraAKThe intracellular drug delivery and anti tumor activity of doxorubicin loaded poly ([gamma]-benzyl l-glutamate)-b-hyaluronan polymersomesBiomaterials2010312882289220053435
- ZhuZLiYLiXPaclitaxel-loaded poly (N-vinylpyrrolidone)-b-poly ([epsilon]-caprolactone) nanoparticles: preparation and antitumor activity in vivoJ Control Release201014243844619896997
- LiSWangAJiangWGuanZPharmacokinetic characteristics and anticancer effects of 5-fluorouracil loaded nanoparticlesBMC Cancer2008810311118412945
- SelvarajVAlagarMAnalytical detection and biological assay of antileukemic drug 5-fluorouracil using gold nanoparticles as probeInt J Pharm200733727528117287098
- BaskicDPopovicSRisticPArsenijevicNNAnalysis of cyclohex-imide-induced apoptosis in human leukocytes: fluorescence microscopy using annexin V/propidium iodide versus acridin orange/ethidium bromideCell Biol Int20063092493216895761
- RibbleDGoldsteinNBNorrisDAShellmanYGA simple technique for quantifying apoptosis in 96-well platesBMC Biotechnol200551215885144
- KuropkatCGriemKClarkJRodriguezERHutchinsonJTaylorSGTSevere cardiotoxicity during 5-fluorouracil chemotherapy: a case and literature reportAm J Clin Oncol19992246647010521060
- De AngelisPMSvendsrudDHKravikKLStokkeTCellular response to 5-fluorouracil(5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recoveryMol Cancer20065204516709241
- HeYCChenJWCaoJPanDYQiaoJGToxicities and therapeutic effect of 5-fluorouracil controlled release implant on tumor-bearing ratsWorld J Gastroenterol200391795179812918123
- FournierEPassiraniCColinNBretonPSagodiraSBenoitJPDevelopment of novel 5-FU-loaded poly (methylidene malonate 2.1. 2)-based microspheres for the treatment of brain cancersEur J Pharm Biopharm20045718919715018974
- FournierEPassiraniCMontero MeneiCTherapeutic effectiveness of novel 5 fluorouracil loaded poly (methylidene malonate 2.1. 2) based microspheres on F98 glioma bearing ratsCancer2003972822282912767096
- DesgouillesSVauthierCBazileDThe design of nanoparticles obtained by solvent evaporation: a comprehensive studyLangmuir20031995049510
- JainAJainSKIn vitro and cell uptake studies for targeting of ligand anchored nanoparticles for colon tumorsEur J Pharm Sci20083540441618824095
- PanyamJWilliamsDDashALeslie-PeleckyDLabhasetwarVSolid-state solubility influences encapsulation and release of hydrophobic drugs from PLGA/PLA nanoparticlesJ Pharm Sci2004931804181415176068
- DuvvuriSGaurav JanoriaKMitraAKEffect of polymer blending on the release of ganciclovir from PLGA microspheresPharm Res20062321522316320000
- RoullinVGDeverreJRLemaireLAnti-cancer drug diffusion within living rat brain tissue: an experimental study using [3H](6)-5-fluorouracil-loaded PLGA microspheresEur J Pharm Biopharm20025329329911976017
- MarchalJABoulaizHSuárezIGrowth inhibition, G 1-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivativesInvest New Drugs20042237938915292708
- OkamotoSSakaiMUchidaJSaitoH5-Florouracil induces apoptotic cell death with G2 phase arrest in human breast cancer grafted in nude miceAnticancer Res199616269927048917373
- YoshikawaRKusunokiMYanagiHDual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapyCancer Res2001611029103711221829
- RoullinVGLemaireLVenier-JulienneMCFaisantNFranconiFBenoitJPRelease kinetics of 5-fluorouracil-loaded microspheres on an experimental rat gliomaAnticancer Res200323212512680190
- RoullinVGMegeMLemaireLInfluence of 5-fluorouracil-loaded microsphere formulation on efficient rat glioma radiosensitizationPharm Res2004211558156315497679
- SastreRLOlmoRTeijónCMunízETeijónJMBlancoMD5-Fluorouracil plasma levels and biodegradation of subcutaneously injected drug-loaded microspheres prepared by spray-drying poly (D, L-lactide) and poly (D, L-lactide-co-glycolide) polymersInt J Pharm200733818019017336474
- KishimotoSKawazoeYIkenoMFukushimaSTakeuchiYContinuous exposure to low-dose cisplatin and apoptosisBiological Pharm Bull20052819541957
- MaedaHWuJSawaTMatsumuraYHoriKTumor vascular permeability and the EPR effect in macromolecular therapeutics: a reviewJ Control Release20006527128410699287
- FukumuraDJainRKTumor microvasculature and microenvironment: targets for anti-angiogenesis and normalizationMicrovasc Res200774728417560615