pH-dependent and cathepsin B activable CaCO₃ nanoprobe for targeted in vivo tumor imaging

References

• Singh D, Kumar R, Das A, Varma SC, Mittal BR. Fluorine-18-2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography masquerading as a case of sporadic malignant peripheral nerve sheath tumor of lower extremity presenting as massive lower limb edema. World J Nucl Med. 2017;16(4):324–327. doi:10.4103/1450-1147.21549429033684
   PubMedGoogle Scholar
• Leufkens AM, van Den Bosch MA, van Leeuwen MS, Siersema PD. Diagnostic accuracy of computed tomography for colon cancer staging: a systematic review. Scand J Gastroenterol. 2011;46(7–8):887–894. doi:10.3109/00365521.2011.57473221504379
   PubMed Web of Science ®Google Scholar
• Morbelli S, Conzi R, Campus C, et al. Contrast-enhanced [18 F] fluorodeoxyglucose-positron emission tomography/computed tomography in clinical oncology: tumor-, site-, and question-based comparison with standard positron emission tomography/computed tomography. Cancer Imaging. 2014;14:10.25609564
   PubMed Web of Science ®Google Scholar
• Xia T, Guan Y, Chen Y, Li J. Askin tumor: CT and FDG-PET/CT imaging findings and follow-up. Medicine (Baltimore). 2014;93(6):e42. doi:10.1097/MD.000000000000004225058144
   PubMedGoogle Scholar
• Haraldsdottir KH, Jonsson T, Halldorsdottir AB, Tranberg KG, Asgeirsson KS. Tumor size of invasive breast cancer on magnetic resonance imaging and conventional imaging (mammogram/ultrasound): comparison with pathological size and clinical implications. Scand J Surg. 2017;106(1):68–73. doi:10.1177/145749691663185526929290
   PubMedGoogle Scholar
• Ma Z, Chen X, Huang Y, et al. MR diffusion-weighted imaging-based subcutaneous tumour volumetry in a xenografted nude mouse model using 3D slicer: an accurate and repeatable method. Sci Rep. 2015;5(15653):15653. doi:10.1038/srep1565326489359
   PubMedGoogle Scholar
• Ogbomo SM, Shi W, Wagh NK, Zhou Z, Brusnahan SK, Garrison JC. 177Lu-labeled HPMA copolymers utilizing cathepsin B and S cleavable linkers: synthesis, characterization and preliminary in vivo investigation in a pancreatic cancer model. Nucl Med Biol. 2013;40(5):606–617. doi:10.1016/j.nucmedbio.2013.01.01123622691
   PubMedGoogle Scholar
• Bu L, Shen B, Cheng Z. Fluorescent imaging of cancerous tissues for targeted surgery. Adv Drug Deliv Rev. 2014;76:21–38. doi:10.1016/j.addr.2014.07.00825064553
   PubMedGoogle Scholar
• Jo D, Hyun H. Structure-inherent targeting of near-infrared fluorophores for image-guided surgery. Chonnam Med J. 2017;53(2):95–102. doi:10.4068/cmj.2017.53.2.9528584787
   PubMedGoogle Scholar
• Li L, Shi W, Wu X, Li X, Ma H. In vivo tumor imaging by a gamma-glutamyl transpeptidase-activatable near-infrared fluorescent probe. Anal Bioanal Chem. 2018;16(10):018–1181.
   Google Scholar
• Gonda K, Watanabe M, Tada H, et al. Quantitative diagnostic imaging of cancer tissues by using phosphor-integrated dots with ultra-high brightness. Sci Rep. 2017;7(1):7509. doi:10.1038/s41598-017-06534-z28790306
   PubMedGoogle Scholar
• Haghiralsadat F, Amoabediny G, Sheikhha MH, Forouzanfar T, Helder MN, Zandieh-Doulabi B. A novel approach on drug delivery: investigation of a new nano-formulation of liposomal doxorubicin and biological evaluation of entrapped doxorubicin on various osteosarcoma cell lines. Cell J. 2017;19(Suppl 1):55–65. doi:10.22074/cellj.2017.450228580308
   PubMedGoogle Scholar
• Huang KW, Chieh JJ, Yeh CK, et al. Ultrasound-induced magnetic imaging of tumors targeted by biofunctional magnetic nanoparticles. ACS Nano. 2017;11(3):3030–3037. doi:10.1021/acsnano.6b0873028276684
   PubMedGoogle Scholar
• Ge X, Dong L, Sun L, et al. New nanoplatforms based on UCNPs linking with polyhedral oligomeric silsesquioxane (POSS) for multimodal bioimaging. Nanoscale. 2015;7(16):7206–7215. doi:10.1039/c5nr00950b25811398
   PubMedGoogle Scholar
• Dai Z, Ma H, Tian L, et al. Construction of a multifunctional nanoprobe for tumor-targeted time-gated luminescence and magnetic resonance imaging in vitro and in vivo. Nanoscale. 2018;10(24):11597–11603. doi:10.1039/c8nr03085e29892761
   PubMedGoogle Scholar
• Deng H, Wang H, Wang M, Li Z, Wu Z. Synthesis and evaluation of 64Cu-DOTA-NT-Cy5.5 as a dual-modality PET/fluorescence probe to image neurotensin receptor-positive tumor. Mol Pharm. 2015;12(8):3054–3061. doi:10.1021/acs.molpharmaceut.5b0032526162008
   PubMedGoogle Scholar
• Wang X, Chen H, Zhang K, et al. An intelligent nanotheranostic agent for targeting, redox-responsive ultrasound imaging, and imaging-guided high-intensity focused ultrasound synergistic therapy. Small. 2014;10(7):1403–1411. doi:10.1002/smll.20130284624288148
   PubMedGoogle Scholar
• Li S, Hu K, Cao W, et al. pH-responsive biocompatible fluorescent polymer nanoparticles based on phenylboronic acid for intracellular imaging and drug delivery. Nanoscale. 2014;6(22):13701–13709. doi:10.1039/c4nr04054f25278283
   PubMedGoogle Scholar
• Tantama M, Hung YP, Yellen G. Imaging intracellular pH in live cells with a genetically encoded red fluorescent protein sensor. J Am Chem Soc. 2011;133(26):10034–10037. doi:10.1021/ja202902d21631110
   PubMed Web of Science ®Google Scholar
• Salaun M, Peng J, Hensley HH, et al. MMP-13 in-vivo molecular imaging reveals early expression in lung adenocarcinoma. PLoS One. 2015;10(7):e0132960. doi:10.1371/journal.pone.013296026193700
   PubMedGoogle Scholar
• Freskos JN, Asmelash B, Gaston KR, et al. Design and synthesis of MMP inhibitors with appended fluorescent tags for imaging and visualization of matrix metalloproteinase enzymes. Bioorg Med Chem Lett. 2013;23(20):5566–5570. doi:10.1016/j.bmcl.2013.08.05023999043
   PubMed Web of Science ®Google Scholar
• Sang Kyoon Kim MBF, Huang L. Targeted delivery of EV peptide to tumor cell cytoplasm using lipid coated calcium carbonate nanoparticles. Cancer Letters. 2012;334(2):311–318. doi:10.1016/j.canlet.2012.07.01122796364
   PubMedGoogle Scholar
• Aggarwal N, Sloane BF. Cathepsin B: multiple roles in cancer. Proteomics Clin Appl. 2014;8(5–6):427–437. doi:10.1002/prca.20130010524677670
   PubMed Web of Science ®Google Scholar
• Bian B, Mongrain S, Cagnol S, et al. Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis. Mol Carcinog. 2016;55(5):671–687. doi:10.1002/mc.2231225808857
   PubMed Web of Science ®Google Scholar
• Ruan J, Zheng H, Rong X, et al. Over-expression of cathepsin B in hepatocellular carcinomas predicts poor prognosis of HCC patients. Mol Cancer. 2016;15(17):17. doi:10.1186/s12943-016-0503-926896959
   PubMedGoogle Scholar
• Gondi CS, Rao JS. Cathepsin B as a cancer target. Expert Opin Ther Targets. 2013;17(3):281–291. doi:10.1517/14728222.2013.74046123293836
   PubMed Web of Science ®Google Scholar
• Habibollahi P, Figueiredo JL, Heidari P, et al. Optical imaging with a cathepsin B activated probe for the enhanced detection of esophageal adenocarcinoma by dual channel fluorescent upper GI endoscopy. Theranostics. 2012;2(2):227–234. doi:10.7150/thno.408822400064
   PubMedGoogle Scholar
• Kisin-Finfer E, Ferber S, Blau R, Satchi-Fainaro R, Shabat D. Synthesis and evaluation of new NIR-fluorescent probes for cathepsin B: ICT versus FRET as a turn-ON mode-of-action. Bioorg Med Chem Lett. 2014;24(11):2453–2458. doi:10.1016/j.bmcl.2014.04.02224767838
   PubMedGoogle Scholar
• Zhou C, Chen T, Wu C, et al. Aptamer CaCO3 nanostructures: a facile, pH-responsive, specific platform for targeted anticancer theranostics. Chem Asian J. 2015;10(1):166–171. doi:10.1002/asia.20140311525377905
   PubMed Web of Science ®Google Scholar
• He X, Li J, An S, Jiang C. pH-sensitive drug-delivery systems for tumor targeting. Ther Deliv. 2013;4(12):1499–1510. doi:10.4155/tde.13.12024304248
   PubMedGoogle Scholar
• Maleki Dizaj S, Barzegar-Jalali M, Zarrintan MH, Adibkia K, Lotfipour F. Calcium carbonate nanoparticles as cancer drug delivery system. Expert Opin Drug Deliv. 2015;12(10):1649–1660. doi:10.1517/17425247.2015.104953026005036
   PubMed Web of Science ®Google Scholar
• Som A, Raliya R, Tian L, et al. Monodispersed calcium carbonate nanoparticles modulate local pH and inhibit tumor growth in vivo. Nanoscale. 2016;8(25):12639–12647. doi:10.1039/c5nr06162h26745389
   PubMed Web of Science ®Google Scholar
• Min KH, Min HS, Lee HJ, et al. pH-controlled gas-generating mineralized nanoparticles: a theranostic agent for ultrasound imaging and therapy of cancers. ACS Nano. 2015;9(1):134–145. doi:10.1021/nn506210a25559896
   PubMed Web of Science ®Google Scholar