Anti-osteoclastogenic effect of epigallocatechin gallate-functionalized gold nanoparticles in vitro and in vivo

References

• Roodman GD. Advances in bone biology: the osteoclast. Endocr Rev. 1996;17(4):308–332. doi:10.1210/edrv-17-4-3088854048
   PubMed Web of Science ®Google Scholar
• Hiyari S, Atti E, Camargo PM, et al. Heritability of periodontal bone loss in mice. J Periodontal Res. 2015;50(6):730–736. doi:10.1111/jre.1225825581386
   PubMedGoogle Scholar
• Park EJ, Kim SA, Choi YM, et al. Capric acid inhibits NO production and STAT3 activation during LPS-induced osteoclastogenesis. PLoS One. 2011;6(11):e27739. doi:10.1371/journal.pone.002773922110749
   PubMedGoogle Scholar
• Yuan L, Wu Y, Ren X, Liu Q, Wang J, Liu X. Isoorientin attenuates lipopolysaccharide-induced pro-inflammatory responses through down-regulation of ROS-related MAPK/NF-kappaB signaling pathway in BV-2 microglia. Mol Cell Biochem. 2014;386(1–2):153–165. doi:10.1007/s11010-013-1854-924114663
   PubMedGoogle Scholar
• Srinivasan S, Koenigstein A, Joseph J, et al. Role of mitochondrial reactive oxygen species in osteoclast differentiation. Ann N Y Acad Sci. 2010;1192:245–252. doi:10.1111/j.1749-6632.2009.05377.x20392243
   PubMedGoogle Scholar
• Park H, Noh AL, Kang JH, Sim JS, Lee DS, Yim M. Peroxiredoxin II negatively regulates lipopolysaccharide-induced osteoclast formation and bone loss via JNK and STAT3. Antioxid Redox Signal. 2015;22(1):63–77. doi:10.1089/ars.2013.574825074339
   PubMed Web of Science ®Google Scholar
• Hou GQ, Guo C, Song GH, et al. Lipopolysaccharide (LPS) promotes osteoclast differentiation and activation by enhancing the MAPK pathway and COX-2 expression in RAW264.7 cells. Int J Mol Med. 2013;32(2):503–510. doi:10.3892/ijmm.2013.140623740407
   PubMed Web of Science ®Google Scholar
• Li L, Khansari A, Shapira L, Graves DT, Amar S. Contribution of interleukin-11 and prostaglandin(s) in lipopolysaccharide-induced bone resorption in vivo. Infect Immun. 2002;70(7):3915–3922. doi:10.1128/iai.70.7.3915-3922.200212065535
   PubMedGoogle Scholar
• Rameshrad M, Razavi BM, Hosseinzadeh H. Protective effects of green tea and its main constituents against natural and chemical toxins: a comprehensive review. Food Chem Toxicol. 2017;100:115–137. doi:10.1016/j.fct.2016.11.03527915048
   PubMed Web of Science ®Google Scholar
• Nakagawa H, Hasumi K, Takami M, et al. Identification of two biologically crucial hydroxyl groups of (-)-epigallocatechin gallate in osteoclast culture. Biochem Pharmacol. 2007;73(1):34–43. doi:10.1016/j.bcp.2006.09.00217034764
   PubMedGoogle Scholar
• Yang EJ, Lee J, Lee SY, et al. EGCG attenuates autoimmune arthritis by inhibition of STAT3 and HIF-1alpha with Th17/Treg control. PLoS One. 2014;9(2):e86062. doi:10.1371/journal.pone.008606224558360
   PubMedGoogle Scholar
• Morinobu A, Biao W, Tanaka S, et al. (-)-Epigallocatechin-3-gallate suppresses osteoclast differentiation and ameliorates experimental arthritis in mice. Arthritis Rheum. 2008;58(7):2012–2018. doi:10.1002/art.2359418576345
   PubMedGoogle Scholar
• Cho AR, Kim JH, Lee DE, et al. The effect of orally administered epigallocatechin-3-gallate on ligature-induced periodontitis in rats. J Periodontal Res. 2013;48(6):781–789. doi:10.1111/jre.1207123581513
   PubMedGoogle Scholar
• Oka Y, Iwai S, Amano H, et al. Tea polyphenols inhibit rat osteoclast formation and differentiation. J Pharmacol Sci. 2012;118(1):55–64.22186621
   PubMed Web of Science ®Google Scholar
• Lin RW, Chen CH, Wang YH, et al. (-)-Epigallocatechin gallate inhibition of osteoclastic differentiation via NF-kappaB. Biochem Biophys Res Commun. 2009;379(4):1033–1037. doi:10.1016/j.bbrc.2009.01.00719150340
   PubMedGoogle Scholar
• An J, Hao D, Zhang Q, et al. Natural products for treatment of bone erosive diseases: the effects and mechanisms on inhibiting osteoclastogenesis and bone resorption. Int Immunopharmacol. 2016;36:118–131. doi:10.1016/j.intimp.2016.04.02427131574
   PubMed Web of Science ®Google Scholar
• Yun JH, Pang EK, Kim CS, et al. Inhibitory effects of green tea polyphenol (-)-epigallocatechin gallate on the expression of matrix metalloproteinase-9 and on the formation of osteoclasts. J Periodontal Res. 2004;39(5):300–307. doi:10.1111/j.1600-0765.2004.00743.x15324350
   PubMedGoogle Scholar
• Tominari T, Matsumoto C, Watanabe K, et al. Epigallocatechin gallate (EGCG) suppresses lipopolysaccharide-induced inflammatory bone resorption, and protects against alveolar bone loss in mice. FEBS Open Bio. 2015;5:522–527. doi:10.1016/j.fob.2015.06.003
   PubMed Web of Science ®Google Scholar
• Lee SH, Kim BJ, Choi HJ, et al. (-)-Epigallocathechin-3-gallate, an AMPK activator, decreases ovariectomy-induced bone loss by suppression of bone resorption. Calcif Tissue Int. 2012;90(5):404–410. doi:10.1007/s00223-012-9584-722434366
   PubMedGoogle Scholar
• Jin P, Wu H, Xu G, Zheng L, Zhao J. Epigallocatechin-3-gallate (EGCG) as a pro-osteogenic agent to enhance osteogenic differentiation of mesenchymal stem cells from human bone marrow: an in vitro study. Cell Tissue Res. 2014;356(2):381–390. doi:10.1007/s00441-014-1797-924682582
   PubMed Web of Science ®Google Scholar
• Choi SY, Song MS, Ryu PD, Lam AT, Joo SW, Lee SY. Gold nanoparticles promote osteogenic differentiation in human adipose-derived mesenchymal stem cells through the Wnt/beta-catenin signaling pathway. Int J Nanomedicine. 2015;10:4383–4392. doi:10.2147/IJN.S7877526185441
   PubMed Web of Science ®Google Scholar
• Lee MJ, Maliakal P, Chen L, et al. Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability. Cancer Epidemiol Biomarkers Prev. 2002;11(10 Pt 1):1025–1032.12376503
   PubMed Web of Science ®Google Scholar
• Shukla R, Chanda N, Zambre A, et al. Laminin receptor specific therapeutic gold nanoparticles (198AuNP-EGCg) show efficacy in treating prostate cancer. Proc Natl Acad Sci U S A. 2012;109(31):12426–12431. doi:10.1073/pnas.112117410922802668
   PubMed Web of Science ®Google Scholar
• Jiang X, Musyanovych A, Röcker C, Landfester K, Mailänder V, Nienhaus GU. Specific effects of surface carboxyl groups on anionic polystyrene particles in their interactions with mesenchymal stem cells. Nanoscale. 2011;3(5):2028. doi:10.1039/c0nr00944j21409242
   PubMed Web of Science ®Google Scholar
• Heo DN, Ko WK, Moon HJ, et al. Inhibition of osteoclast differentiation by gold nanoparticles functionalized with cyclodextrin curcumin complexes. ACS Nano. 2014;8(12):12049–12062. doi:10.1021/nn504329u25420230
   PubMed Web of Science ®Google Scholar
• Tautzenberger A, Kovtun A, Ignatius A. Nanoparticles and their potential for application in bone. Int J Nanomedicine. 2012;7:4545–4557. doi:10.2147/IJN.S3412722923992
   PubMed Web of Science ®Google Scholar
• Granja A, Frias I, Neves AR, Pinheiro M, Reis S. Therapeutic potential of epigallocatechin gallate nanodelivery systems. Biomed Res Int. 2017;2017:5813793. doi:10.1155/2017/581379328791306
   PubMedGoogle Scholar
• Ghosh P, Han G, De M, Kim CK, Rotello VM. Gold nanoparticles in delivery applications. Adv Drug Deliv Rev. 2008;60(11):1307–1315. doi:10.1016/j.addr.2008.03.01618555555
   PubMed Web of Science ®Google Scholar
• Levy R, Shaheen U, Cesbron Y, See V. Gold nanoparticles delivery in mammalian live cells: a acritical review. Nano Rev. 2010;1(1):4889. doi: 10.3402/nano.v1i0.4889.
   PubMedGoogle Scholar
• Tran NTT, Wang TH, Lin CY, Tai Y. Synthesis of methotrexate-conjugated gold nanoparticles with enhanced cancer therapeutic effect. Biochem Eng J. 2013;78:175–180. doi:10.1016/j.bej.2013.04.017
   Web of Science ®Google Scholar
• Wang F, Wang YC, Dou S, Xiong MH, Sun TM, Wang J. Doxorubicin-tethered responsive gold nanoparticles facilitate intracellular drug delivery for overcoming multidrug resistance in cancer cells. ACS Nano. 2011;5(5):3679–3692. doi:10.1021/nn200007z21462992
   PubMed Web of Science ®Google Scholar
• Conners CM, Bhethanabotla VR, Gupta VK. Concentration-dependent effects of alendronate and pamidronate functionalized gold nanoparticles on osteoclast and osteoblast viability. J Biomed Mater Res B Appl Biomater. 2017;105(1):21–29. doi:10.1002/jbm.b.3352726372402
   PubMedGoogle Scholar
• Sul OJ, Kim JC, Kyung TW, et al. Gold nanoparticles inhibited the receptor activator of nuclear factor-kappab ligand (RANKL)-induced osteoclast formation by acting as an antioxidant. Biosci Biotechnol Biochem. 2010;74(11):2209–2213. doi:10.1271/bbb.10037521071867
   PubMed Web of Science ®Google Scholar
• Li JJ, Kawazoe N, Chen G. Gold nanoparticles with different charge and moiety induce differential cell response on mesenchymal stem cell osteogenesis. Biomaterials. 2015;54:226–236. doi:10.1016/j.biomaterials.2015.03.00125858865
   PubMed Web of Science ®Google Scholar
• Han G, Ghosh P, Rotello VM. Functionalized gold nanoparticles for drug delivery. Nanomedicine (Lond). 2007;2(1):113–123. doi:10.2217/17435889.2.1.11317716197
   PubMed Web of Science ®Google Scholar
• Lu YC, Luo PC, Huang CW, Leu YL. Augmented cellular uptake of nanoparticles using tea catechins_ effect of surface modification on nanoparticle–cell interaction. Nanoscale. 2014;6(17):10297–10306. doi:10.1039/c4nr00617h25069428
   PubMed Web of Science ®Google Scholar
• Mukherjee S, Ghosh S, Das DK, et al. Gold-conjugated green tea nanoparticles for enhanced anti-tumor activities and hepatoprotection–synthesis, characterization and in vitro evaluation. J Nutr Biochem. 2015;26(11):1283–1297. doi:10.1016/j.jnutbio.2015.06.00326310506
   PubMed Web of Science ®Google Scholar
• Liang J, Cao L, Zhang L, Wan XC. Preparation, characterization, and in vitro antitumor activity of folate conjugated chitosan coated EGCG nanoparticles. Food Sci Biotechnol. 2014;23(2):569–575. doi:10.1007/s10068-014-0078-4
   Web of Science ®Google Scholar
• Dehshahri S, Wink M, Afsharypuor S, Asghari G, Mohagheghzadeh A. Antioxidant activity of methanolic leaf extract of moringa peregrina. Fiori Res Pharm Sci. 2012;2(8):111–118.
   Google Scholar
• Teobaldi G, Zerbetto F. Adsorption of organic molecules on gold electrodes. J Phys Chem C. 2007;111(37):13879–13885. doi:10.1021/jp074017g
   Web of Science ®Google Scholar
• Al-Johani H, Abou-Hamad E, Jedidi A, et al. The structure and binding mode of citrate in the stabilization of gold nanoparticles. Nat Chem. 2017;9(9):890–895. doi:10.1038/nchem.275228837175
   PubMedGoogle Scholar
• Perdew JP, Burke K, Ernzerhof M. Generalized gradient approximation made simple. Phys Rev Lett. 1996;77(18):3865–3868. doi:10.1103/PhysRevLett.77.386510062328
   PubMed Web of Science ®Google Scholar
• Delley B. The conductor-like screening model for polymers and surfaces. Mol Simul. 2006;32(2):117–123. doi:10.1080/08927020600589684
   Web of Science ®Google Scholar
• Delley B. From molecules to solids with the DMol3 approach. J Chem Phys. 2000;113(18):7756–7764. doi:10.1063/1.1316015
   Web of Science ®Google Scholar
• Eruslanov E, Kusmartsev S. Identification of ROS using oxidized DCFDA and flow-cytometry. Methods Mol Biol. 2010;594:57–72. doi:10.1007/978-1-60761-411-1_420072909
   PubMedGoogle Scholar
• Liu S, Zhu L, Zhang J, Yu J, Cheng X, Peng B. Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-kappaB-dependent autophagic pathway. Biochem Pharmacol. 2016;106:82–93. doi:10.1016/j.bcp.2016.03.00226947453
   PubMed Web of Science ®Google Scholar
• Zhang J, Zhu L, Yan P, Peng B. Effect of BioAggregate on receptor activator of nuclear factor-kappa B ligand-induced osteoclastogenesis from murine macrophage cell line in vitro. J Endod. 2015;41(8):1265–1271. doi:10.1016/j.joen.2015.03.02125975181
   PubMedGoogle Scholar
• Domingos RF, Baalousha MA, Ju-Nam Y, et al. Characterizing manufactured nanoparticles in the environment: multimethod determination of particle sizes. Environ Sci Technol. 2009;43(19):7277–7284. doi:10.1021/es900249m19848134
   PubMed Web of Science ®Google Scholar
• Cristina M, Paolo M, Gianluca F, et al. A Poloxamer-407 modified liposome encapsulating epigallocatechin-3-gallate in the presence of magnesium: characterization and protective effect against oxidative damage. Int J of Pharmaceutics. 2018;552:225–234. doi:10.1016/j.ijpharm.2018.10.004
   PubMed Web of Science ®Google Scholar
• Li G, Chen Y, Hou Z, et al. Pro-oxidative activities and dose–response relationship of (−)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro. Carcinogenesis. 2010;31:902–910. doi:10.1093/carcin/bgq03920159951
   PubMed Web of Science ®Google Scholar
• Khan UA, Hashimi SM, Bakr MM, Forwood MR, Morrison NA. Foreign body giant cells and osteoclasts are TRAP positive, have podosome-belts and both require OC-STAMP for cell fusion. J Cell Biochem. 2013;114(8):1772–1778. doi:10.1002/jcb.2451823444125
   PubMedGoogle Scholar
• Lee EJ, Kim JL, Gong JH, Park SH, Kang YH. Inhibition of osteoclast activation by phloretin through disturbing alphavbeta3 integrin-c-Src pathway. Biomed Res Int. 2015;2015:680145.25834823
   PubMed Web of Science ®Google Scholar
• Kanzaki H, Shinohara F, Kajiya M, Kodama T. The Keap1/Nrf2 protein axis plays a role in osteoclast differentiation by regulating intracellular reactive oxygen species signaling. J Biol Chem. 2013;288(32):23009–23020. doi:10.1074/jbc.M113.47854523801334
   PubMed Web of Science ®Google Scholar
• Li L, Sapkota M, Gao M, Choi H, Soh Y, Macrolactin F. Inhibits RANKL-mediated osteoclastogenesis by suppressing Akt, MAPK and NFATc1 pathways and promotes osteoblastogenesis through a BMP-2/smad/Akt/Runx2 signaling pathway. Eur J Pharmacol. 2017;815:202–209. doi:10.1016/j.ejphar.2017.09.01528919027
   PubMed Web of Science ®Google Scholar
• Li Q, Verma IM. NF-kappaB regulation in the immune system. Nat Rev Immunol. 2002;2(10):725–734. doi:10.1038/nri91012360211
   PubMed Web of Science ®Google Scholar
• De Jong WH, Hagens WI, Krystek P, Burger MC, Sips AJ, Geertsma RE. Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials. 2008;29(12):1912–1919. doi:10.1016/j.biomaterials.2007.12.03718242692
   PubMed Web of Science ®Google Scholar
• Terentyuk GS, Maslyakova GN, Suleymanova LV, et al. Circulation and distribution of gold nanoparticles and induced alterations of tissue morphology at intravenous particle delivery. J Biophotonics. 2009;2(5):292–302. doi:10.1002/jbio.20091000519434616
   PubMed Web of Science ®Google Scholar
• Tsoi KM, MacParland SA, Ma XZ, et al. Mechanism of hard-nanomaterial clearance by the liver. Nat Mater. 2016;15(11):1212–1221. doi:10.1038/nmat471827525571
   PubMed Web of Science ®Google Scholar
• Michelle L, Choyke PL, Kobayashi H. Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats. Nanomedicine. 2008;3(5):703–717. doi:10.2217/17435889.3.5.70318817471
   PubMedGoogle Scholar