In vitro cytotoxicity and transfection efficiency of pDNA encoded p53 gene-loaded chitosan-sodium deoxycholate nanoparticles

References

• Janes K, Calvo P, Alonso M. Polysaccharide colloidal particles as delivery systems for macromolecules. Adv Drug Deliv Rev. 2001;47:83–97.11251247
   PubMed Web of Science ®Google Scholar
• Richardson SW, Kolbe HJ, Duncan R. Potential of low molecular mass chitosan as a DNA delivery system: biocompatibility, body distribution and ability to complex and protect DNA. Int J Pharm. 1999;178:231–243.10205643
   PubMed Web of Science ®Google Scholar
• Cui Z, Mumper RJ. Chitosan-based nanoparticles for topical genetic immunization. J Control Release. 2001;75:409–419.11489327
   PubMed Web of Science ®Google Scholar
• Illum L, Jabbal-Gill I, Hinchcliffe M, Fisher A, Davis S. Chitosan as a novel nasal delivery system for vaccines. Adv Drug Deliv Rev. 2001;51:81–96.11516781
   PubMed Web of Science ®Google Scholar
• Panyam J, Labhasetwar V. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev. 2003;55:329–347.12628320
   PubMed Web of Science ®Google Scholar
• Corsi K, Chellat F, Yahia LH, Fernandes JC. Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan-DNA nanoparticles. Biomaterials. 2003;24:1255–1264.12527266
   PubMed Web of Science ®Google Scholar
• Romøren K, Thu BJ, Evensen Ø. Immersion delivery of plasmid DNA: II. A study of the potentials of a chitosan based delivery system in rainbow trout (Oncorhynchus mykiss) fry. J Control Release. 2002;85:215–225.12480326
   PubMed Web of Science ®Google Scholar
• Dufès C, Uchegbu IF, Schätzlein AG. Dendrimers in gene delivery. Adv Drug Deliv Rev. 2005;57(15):2177–2202. doi:10.1016/j.addr.2005.09.01716310284
   PubMed Web of Science ®Google Scholar
• Khatri K, Goyal AK, Gupta PN, Mishra N, Vyas SP. Plasmid DNA loaded chitosan nanoparticles for nasal mucosal immunization against hepatitis B. Int J Pharm. 2008;354:235–241. doi:10.1016/j.ijpharm.2007.11.02718182259
   PubMed Web of Science ®Google Scholar
• Sun CJ, Pan SP, Xie QX, Xiao LJ. Preparation of chitosan-plasmid DNA nanoparticles encoding zona pellucida glycoprotein-3α and its expression in mouse. Mol Reprod and Dev. 2004;68:182–188. doi:10.1002/mrd.20058
   PubMed Web of Science ®Google Scholar
• Kumar M, Behera AK, Lockey RF, et al. Intranasal gene transfer by chitosan–DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection. Hum Gene Ther. 2002;13:1415–1425. doi:10.1089/1043034026018505812215263
   PubMed Web of Science ®Google Scholar
• Bivas-Benita M, van Meijgaarden KE, Franken KL, et al. Pulmonary delivery of chitosan-DNA nanoparticles enhances the immunogenicity of a DNA vaccine encoding HLA-A* 0201-restricted T-cell epitopes of Mycobacterium tuberculosis. Vaccine. 2004;22:1609–1615. doi:10.1016/j.vaccine.2003.09.04415068842
   PubMed Web of Science ®Google Scholar
• Lee JI, Kim HS, Yoo HS. DNA nanogels composed of chitosan and pluronic with thermo-sensitive and photo-crosslinking properties. Int J Pharm. 2009;373:93–99. doi:10.1016/j.ijpharm.2009.01.01619429293
   PubMed Web of Science ®Google Scholar
• Mao HQ, Roy K, Troung-Le VL, et al. Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency. J Control Release. 2001;70:399–421.11182210
   PubMed Web of Science ®Google Scholar
• Lee K, Kwon I, Kim Y-H, Jo W, Jeong S. Preparation of chitosan self-aggregates as a gene delivery system. J Control Release. 1998;51:213–220.9685919
   PubMed Web of Science ®Google Scholar
• Erbacher P, Zou S, Bettinger T, Steffan A-M, Remy J-S. Chitosan-based vector/DNA complexes for gene delivery: biophysical characteristics and transfection ability. Pharm Res. 1998;15:1332–1339.9755882
   PubMed Web of Science ®Google Scholar
• Nicolazzo JA, Reed BL, Finnin BC. Buccal penetration enhancers—how do they really work? J Control Release. 2005;105:1–15. doi:10.1016/j.jconrel.2005.01.02415894393
   PubMed Web of Science ®Google Scholar
• Chae SY, Son S, Lee M, Jang M-K, Nah J-W. Deoxycholic acid-conjugated chitosan oligosaccharide nanoparticles for efficient gene carrier. J Control Release. 2005;109:330–344. doi:10.1016/j.jconrel.2005.09.04016271416
   PubMed Web of Science ®Google Scholar
• Romeo V, Gries W, Xia W, Sileno A, Pimplaskar H, Behl C. Optimization of systemic nasal drug delivery with pharmaceutical excipients. Adv Drug Deliv Rev. 1998;29:117–133.10837583
   PubMed Web of Science ®Google Scholar
• Fan W, Yan W, Xu Z, Ni H. Formation mechanism of monodisperse, low molecular weight chitosan nanoparticles by ionic gelation technique. Coll Surf B. 2012;90:21–27. doi:10.1016/j.colsurfb.2011.09.042
   PubMed Web of Science ®Google Scholar
• Koukaras EN, Papadimitriou SA, Bikiaris DN, Froudakis GE. Insight on the formation of chitosan nanoparticles through ionotropic gelation with tripolyphosphate. Mol Pharm. 2012;9(10):2856–2862. doi:10.1021/mp300162j22845012
   PubMedGoogle Scholar
• Galipeau J, Li H, Paquin A, Sicilia F, Karpati G, Nalbantoglu J. Vesicular stomatitis virus G pseudotyped retrovector mediates effective in vivo suicide gene delivery in experimental brain cancer. Cancer Res. 1999;59:2384–2394.10344748
   PubMed Web of Science ®Google Scholar
• Lee M, Nah J-W, Kwon Y, Koh JJ, Ko KS, Kim SW. Water-soluble and low molecular weight chitosan-based plasmid DNA delivery. Pharm Res. 2001;18:427–431.11451027
   PubMed Web of Science ®Google Scholar
• Zhang H, Neau SH. In vitro degradation of chitosan by a commercial enzyme preparation: effect of molecular weight and degree of deacetylation. Biomaterials. 2001;22:1653–1658.11374467
   PubMed Web of Science ®Google Scholar
• Fisher DE. Apoptosis in cancer therapy: crossing the threshold. Cell. 1994;78(4):539–542.8069905
   PubMed Web of Science ®Google Scholar
• Loughery J, Cox M, Smith LM, Meek DW. Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters. Nucleic Acids Res. 2014;42:7666–7680. doi:10.1093/nar/gku50124928858
   PubMed Web of Science ®Google Scholar
• Cadete A, Figueiredo L, Lopes R, Calado C, Almeida A, Gonçalves L. Development and characterization of a new plasmid delivery system based on chitosan–sodium deoxycholate nanoparticles. Eur J Pharm Sci. 2012;45:451–458. doi:10.1016/j.ejps.2011.09.01821986445
   PubMed Web of Science ®Google Scholar
• Ammar HO, El-Nahhas S, Ghorab M, Salama A. Chitosan/cyclodextrin nanoparticles as drug delivery system. J Incl Phenom Macrocycl Chem. 2012;72:127–136. doi:10.1007/s10847-011-9950-5
   Web of Science ®Google Scholar
• Barbas C, Burton D, Scott J, Silverman G. Quantitation of DNA and RNA. Cold Spring Harb Protoc. 2007;11:pdb–ip47.
   Google Scholar
• Lotfipour F, Hallaj-Nezhadi S, Valizadeh H, et al. Preparation of chitosan-plasmid DNA nanoparticles encoding interleukin-12 and their expression in CT-26 colon carcinoma cells. J Pharm Pharm Sci. 2011;14:181–195.21733408
   PubMed Web of Science ®Google Scholar
• Mansouri S, Cuie Y, Winnik F, et al. Characterization of folate-chitosan-DNA nanoparticles for gene therapy. Biomaterials. 2006;27:2060–2065. doi:10.1016/j.biomaterials.2005.09.02016202449
   PubMed Web of Science ®Google Scholar
• Bozkir A, Saka OM. Chitosan nanoparticles for plasmid DNA delivery: effect of chitosan molecular structure on formulation and release characteristics. Drug Deliv. 2004;11:107–112. doi:10.1080/1071754049028070515200009
   PubMed Web of Science ®Google Scholar
• Repetto G, Del Peso A, Zurita JL. Neutral red uptake assay for the estimation of cell viability/cytotoxicity. Nat Protoc. 2008;3(7):1125–1131. doi:10.1038/nprot.2008.7518600217
   PubMed Web of Science ®Google Scholar
• Aral C, Akbuga J. Preparation and in vitro transfection efficiency of chitosan microspheres containing plasmid DNA: poly (L-lysine) complexes. J Pharm Pharm Sci. 2003;6:321–326.14738712
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method. Methods. 2001;25:402–408. doi:10.1006/meth.2001.126211846609
   PubMed Web of Science ®Google Scholar
• Bordelon H, Biris AS, Sabliov CM, Monroe WT. Characterization of plasmid DNA location within chitosan/PLGA/pDNA nanoparticle complexes designed for gene delivery. J Nanomater. 2011;2011:8. doi:10.1155/2011/952060
   Web of Science ®Google Scholar
• Deng QY, Zhou CR, Luo BH. Preparation and characterization of chitosan nanoparticles containing lysozyme. Pharm Biol. 2006;44:336–342. doi:10.1080/13880200600746246
   Web of Science ®Google Scholar
• Nesalin JAJ, Smith AA. Preparation and evaluation of chitosan nanoparticles containing zidovudine. Asian J Pharm Sci. 2012;7:80–84.
   Google Scholar
• Amidi M, Romeijn SG, Borchard G, Junginger HE, Hennink WE, Jiskoot W. Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system. J Control Release. 2006;111:107–116. doi:10.1016/j.jconrel.2005.11.01416380189
   PubMed Web of Science ®Google Scholar
• Mohammadpour Dounighi N, Eskandari R, Avadi MR, Zolfagharian H, Mir Mohammad Sadeghi A, Rezayat M. Preparation and in vitro characterization of chitosan nanoparticles containing Mesobuthus eupeus scorpion venom as an antigen delivery system. J Venom Anim Toxins Incl Trop Dis. 2012;18:44–52.
   Web of Science ®Google Scholar
• Yuan Y, Tan J, Wang Y, Qian C, Zhang M. Chitosan nanoparticles as non-viral gene delivery vehicles based on atomic force microscopy study. Acta Biochim Biophys Sin. 2009;41:515–526.19499155
   PubMedGoogle Scholar