129
Views
12
CrossRef citations to date
0
Altmetric
Original Research

Chitosan Nanoparticles Strengthen Vγ9Vδ2 T-Cell Cytotoxicity Through Upregulation Of Killing Molecules And Cytoskeleton Polarization

, , , , &
Pages 9325-9336 | Published online: 29 Nov 2019

References

  • Bonneville M, O’Brien RL, Born WK. Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity. Nat Rev Immunol. 2010;10(7):467–478. doi:10.1038/nri278120539306
  • Gao Y, Yang W, Pan M, et al. Gamma delta T cells provide an early source of interferon gamma in tumor immunity. J Exp Med. 2003;198(3):433–442. doi:10.1084/jem.2003058412900519
  • Gentles AJ, Newman AM, Liu CL, et al. The prognostic landscape of genes and infiltrating immune cells across human cancers. Nat Med. 2015;21(8):938–945. doi:10.1038/nm.390926193342
  • Wu D, Wu P, Qiu F, Wei Q, Huang J. Human gammadelta T-cell subsets and their involvement in tumor immunity. Cell Mol Immunol. 2017;14(3):245–253. doi:10.1038/cmi.2016.5527890919
  • Alnaggar M, Xu Y, Li J, et al. Allogenic Vgamma9Vdelta2 T cell as new potential immunotherapy drug for solid tumor: a case study for cholangiocarcinoma. J Immunother Cancer. 2019;7(1):36. doi:10.1186/s40425-019-0501-830736852
  • Poggi A, Zocchi MR. Gammadelta T lymphocytes as a first line of immune defense: old and new ways of antigen recognition and implications for cancer immunotherapy. Front Immunol. 2014;5:575. doi:10.3389/fimmu.2014.0057525426121
  • Anitha A, Sowmya S, Kumar PTS, et al. Chitin and chitosan in selected biomedical applications. Prog Polym Sci. 2014;39(9):1644–1667. doi:10.1016/j.progpolymsci.2014.02.008
  • de Oliveira Pedro R, Hoffmann S, Pereira S, Goycoolea FM, Schmitt CC, Neumann MG. Self-assembled amphiphilic chitosan nanoparticles for quercetin delivery to breast cancer cells. Eur J Pharm Biopharm. 2018;131:203–210. doi:10.1016/j.ejpb.2018.08.00930145220
  • Kean T, Thanou M. Biodegradation, biodistribution and toxicity of chitosan. Adv Drug Deliv Rev. 2010;62(1):3–11. doi:10.1016/j.addr.2009.09.00419800377
  • Shi GN, Zhang CN, Xu R, et al. Enhanced antitumor immunity by targeting dendritic cells with tumor cell lysate-loaded chitosan nanoparticles vaccine. Biomaterials. 2017;113:191–202. doi:10.1016/j.biomaterials.2016.10.04727816821
  • Carroll EC, Jin L, Mori A, et al. The vaccine adjuvant chitosan promotes cellular immunity via DNA sensor cGAS-STING-dependent induction of Type I interferons. Immunity. 2016;44(3):597–608. doi:10.1016/j.immuni.2016.02.00426944200
  • Castro F, Pinto ML, Silva AM, et al. Pro-inflammatory chitosan/poly(gamma-glutamic acid) nanoparticles modulate human antigen-presenting cells phenotype and revert their pro-invasive capacity. Acta Biomater. 2017;63:96–109. doi:10.1016/j.actbio.2017.09.01628919508
  • Wu Y, Sims RC, Zhou A. AFM resolves effects of ethambutol on nanomechanics and nanostructures of single dividing mycobacteria in real-time. Phys Chem Chem Phy. 2014;16:19156–19164. doi:10.1039/C4CP01317D
  • Wu YZ, McEwen GD, Harihar S, Baker SM, DeWald DB, Zhou AH. BRMS1 expression alters the ultrastructural, biomechanical and biochemical properties of MDA-MB-435 human breast carcinoma cells: an AFM and Raman microspectroscopy study. Cancer Lett. 2010;293(1):82–91. doi:10.1016/j.canlet.2009.12.01620083343
  • McEwen GD, Wu Y, Tang M, et al. Subcellular spectroscopic markers, topography and nanomechanics of human lung cancer and breast cancer cells examined by combined confocal Raman microspectroscopy and atomic force microscopy. Analyst. 2013;138:787–797. doi:10.1039/C2AN36359C23187307
  • Meraviglia S, Lo Presti E, Dieli F, Stassi G. Gammadelta T cell-based anticancer immunotherapy: progress and possibilities. Immunotherapy. 2015;7(9):949–951. doi:10.2217/imt.15.6826569071
  • Huang X, Guo H, Wang C, et al. Detection of CD28/CD86 co-stimulatory molecules and surface properties of T and dendritic cells: an AFM study. Scanning. 2016;38(4):365–375. doi:10.1002/sca.v38.426507362
  • Hu M, Wang J, Zhao H, Dong S, Cai J. Nanostructure and nanomechanics analysis of lymphocyte using AFM: from resting, activated to apoptosis. J Biomech. 2009;42(10):1513–1519. doi:10.1016/j.jbiomech.2009.03.05119477449
  • Wang J, Wan Z, Liu W, et al. Atomic force microscope study of tumor cell membranes following treatment with anti-cancer drugs. Biosens Bioelectron. 2009;25(4):721–727. doi:10.1016/j.bios.2009.08.01119734031
  • Cui YH, Hu ZX, Gao ZX, et al. Airborne particulate matter impairs corneal epithelial cells migration via disturbing FAK/RhoA signaling pathway and cytoskeleton organization. Nanotoxicology. 2018;12(4):312–324. doi:10.1080/17435390.2018.144065129463199
  • Billadeau DD, Nolz JC, Gomez TS. Regulation of T-cell activation by the cytoskeleton. Nat Rev Immunol. 2007;7(2):131–143. doi:10.1038/nri202117259969
  • Kuhn JR, Poenie M. Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing. Immunity. 2002;16(1):111–121. doi:10.1016/S1074-7613(02)00262-511825570
  • Cao G, Wang Q, Li G, et al. mTOR inhibition potentiates cytotoxicity of Vgamma4 gammadelta T cells via up-regulating NKG2D and TNF-alpha. J Leukoc Biol. 2016;100(5):1181–1189. doi:10.1189/jlb.5A0116-053RR27256566
  • Zeng D, Lin J, He H, et al. Therapeutic effect of targeted Fas-expressing adenoviruses method combining gamma delta T cells in a mouse model of human ovarian carcinoma. Oncol Lett. 2018;15(2):2555–2561. doi:10.3892/ol.2017.759929434973
  • Brandes M, Willimann K, Bioley G, et al. Cross-presenting human T cells induce robust CD8+ T cell responses. Proc Natl Acad Sci. 2009;106(7):2307–2312. doi:10.1073/pnas.081005910619171897
  • Brandes M, Willimann K, Moser B. Professional antigen-presentation function by human gamma delta T Cells. Science. 2005;309(5732):264–268. doi:10.1126/science.111026715933162
  • Hines MR, Nichols KE. Go with the flow: perforin and CD107a in HLH. Blood. 2017;129(22):2954–2955. doi:10.1182/blood-2017-04-77319228572174
  • Sanyakamdhorn S, Agudelo D, Tajmir-Riahi HA. Encapsulation of antitumor drug Doxorubicin and its analogue by chitosan nanoparticles. Biomacromolecules. 2013;14(2):557–563. doi:10.1021/bm301857723305154
  • Alexander AAZ, Maniar A, Cummings JS, et al. Isopentenyl pyrophosphate-activated CD56+ T lymphocytes display potent antitumor activity toward human squamous cell carcinoma. Clin Cancer Res. 2008;14(13):4232–4240. doi:10.1158/1078-0432.CCR-07-491218594005
  • Li Z, Xu Q, Peng H, Cheng R, Sun Z, Ye Z. IFN-gamma enhances HOS and U2OS cell lines susceptibility to gammadelta T cell-mediated killing through the Fas/Fas ligand pathway. Int Immunopharmacol. 2011;11(4):496–503. doi:10.1016/j.intimp.2011.01.00121238618
  • Lafouresse F, Vasconcelos Z, Cotta-de-Almeida V, Dupre L. Actin cytoskeleton control of the comings and goings of T lymphocytes. Tissue Antigens. 2013;82(5):301–311. doi:10.1111/tan.2013.82.issue-524131017