Analysis of toxicity and anticancer activity of micelles of sodium alginate-curcumin

References

• Salehi B, Stojanović-Radić Z, Matejić J, et al. The therapeutic potential of curcumin: a review of clinical trials. Eur J Med Chem. 2019;163:527–545. doi:10.1016/J.EJMECH.2018.12.01630553144
   PubMed Web of Science ®Google Scholar
• Wahlström B, Blennow G. A study on the fate of curcumin in the rat. Acta Pharmacol Toxicol (Copenh). 2009;43(2):86–92. doi:10.1111/j.1600-0773.1978.tb02240.x
   Google Scholar
• Kumar S, Kesharwani SS, Mathur H, Tyagi M, Bhat GJ, Tummala H. Molecular complexation of curcumin with pH sensitive cationic copolymer enhances the aqueous solubility, stability and bioavailability of curcumin. Eur J Pharm Sci. 2016;82:86–96. doi:10.1016/J.EJPS.2015.11.01026588875
   PubMed Web of Science ®Google Scholar
• Kesharwani SS, Ahmad R, Bakkari MA, et al. Site-directed non-covalent polymer-drug complexes for inflammatory bowel disease (IBD): formulation development, characterization and pharmacological evaluation. J Control Release. 2018;290:165–179. doi:10.1016/j.jconrel.2018.08.00430142410
   PubMed Web of Science ®Google Scholar
• Karewicz A, Bielska D, Loboda A, et al. Curcumin-containing liposomes stabilized by thin layers of chitosan derivatives. Colloids Surf B Biointerfaces. 2013;109:307–316. doi:10.1016/j.colsurfb.2013.03.05923668985
   PubMed Web of Science ®Google Scholar
• Klippstein R, Wang JT-W, El-Gogary RI, et al. Passively targeted curcumin-loaded PEGylated PLGA nanocapsules for colon cancer therapy in vivo. Small. 2015;11(36):4704–4722. doi:10.1002/smll.20140379926140363
   PubMed Web of Science ®Google Scholar
• Saranya TS, Rajan VK, Biswas R, Jayakumar R, Sathianarayanan S. Synthesis, characterisation and biomedical applications of curcumin conjugated chitosan microspheres. Int J Biol Macromol. 2018;110:227–233. doi:10.1016/j.ijbiomac.2017.12.04429229242
   PubMed Web of Science ®Google Scholar
• Rojewska A, Karewicz A, Boczkaja K, et al. Modified bionanocellulose for bioactive wound-healing dressing. Eur Polym J. 2017;96:200–209. doi:10.1016/J.EURPOLYMJ.2017.09.010
   Web of Science ®Google Scholar
• Jaiswal S, Mishra P. Antimicrobial and antibiofilm activity of curcumin-silver nanoparticles with improved stability and selective toxicity to bacteria over mammalian cells. Med Microbiol Immunol. 2018;207(1):39–53. doi:10.1007/s00430-017-0525-y29081001
   PubMed Web of Science ®Google Scholar
• Novelli F, De Santis S, Diociaiuti M, et al. Curcumin loaded nanocarriers obtained by self-assembly of a linear d,l-octapeptide-poly(ethylene glycol) conjugate. Eur Polym J. 2018;98:28–38. doi:10.1016/J.EURPOLYMJ.2017.11.010
   Web of Science ®Google Scholar
• Waghela BN, Sharma A, Dhumale S, Pandey SM, Pathak C. Curcumin conjugated with PLGA potentiates sustainability, anti-proliferative activity and apoptosis in human colon carcinoma cells. Anto RJ, ed PLoS One. 2015;10(2):e0117526. doi:10.1371/journal.pone.0117526.25692854
   PubMed Web of Science ®Google Scholar
• Raveendran R, Bhuvaneshwar GS, Sharma CP. Hemocompatible curcumin–dextran micelles as pH sensitive pro-drugs for enhanced therapeutic efficacy in cancer cells. Carbohydr Polym. 2016;137:497–507. doi:10.1016/J.CARBPOL.2015.11.01726686156
   PubMed Web of Science ®Google Scholar
• Ni J, Tian F, Dahmani FZ, et al. Curcumin-carboxymethyl chitosan (CNC) conjugate and CNC/LHR mixed polymeric micelles as new approaches to improve the oral absorption of P-gp substrate drugs. Drug Deliv. 2016;23(9):3424–3435. doi:10.1080/10717544.2016.118962527198856
   PubMed Web of Science ®Google Scholar
• Jiang Z, Dong X, Liu H, Wang Y, Zhang L, Sun Y. Multifunctionality of self-assembled nanogels of curcumin-hyaluronic acid conjugates on inhibiting amyloid β-protein fibrillation and cytotoxicity. React Funct Polym. 2016;104:22–29. doi:10.1016/J.REACTFUNCTPOLYM.2016.04.019
   Web of Science ®Google Scholar
• Sarika PR, James NR, Kumar PRA, Raj DK. Galactosylated alginate-curcumin micelles for enhanced delivery of curcumin to hepatocytes. Int J Biol Macromol. 2016;86:1–9. doi:10.1016/J.IJBIOMAC.2016.01.03726774374
   PubMedGoogle Scholar
• Lachowicz D, Karabasz A, Bzowska M, Szuwarzyński M, Karewicz A, Nowakowska M. Blood-compatible, stable micelles of sodium alginate – curcumin bioconjugate for anti-cancer applications. Eur Polym J. 2019;113:208–219. doi:10.1016/J.EURPOLYMJ.2019.01.058
   Web of Science ®Google Scholar
• Kesharwani SS, Kaur S, Tummala H, Sangamwar AT. Multifunctional approaches utilizing polymeric micelles to circumvent multidrug resistant tumors. Colloids Surf B Biointerfaces. 2019;173:581–590. doi:10.1016/J.COLSURFB.2018.10.02230352379
   PubMed Web of Science ®Google Scholar
• Corbett TH, Griswold DP, Roberts BJ, Peckham JC, Schabel FM. Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res. 1975;35(9):2434–2439.1149045
   PubMed Web of Science ®Google Scholar
• Karabasz A, Szczepanowicz K, Cierniak A, Bereta J, Bzowska M. In vitro toxicity studies of biodegradable, polyelectrolyte nanocapsules. Int J Nanomedicine. 2018;13:5159–5172. doi:10.2147/IJN.S16912030233178
   PubMed Web of Science ®Google Scholar
• Naksuriya O, Okonogi S, Schiffelers RM, Hennink WE. Curcumin nanoformulations: a review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment. Biomaterials. 2014;35(10):3365–3383. doi:10.1016/J.BIOMATERIALS.2013.12.09024439402
   PubMed Web of Science ®Google Scholar
• Zhao G, Dong X, Sun Y. Self-assembled curcumin–poly(carboxybetaine methacrylate) conjugates: potent nano-inhibitors against amyloid β-protein fibrillogenesis and cytotoxicity. Langmuir. 2019;35(5):1846–1857. doi:10.1021/acs.langmuir.8b0192130134656
   PubMedGoogle Scholar
• Tian C, Asghar S, Xu Y, et al. The effect of the molecular weight of hyaluronic acid on the physicochemical characterization of hyaluronic acid-curcumin conjugates and in vitro evaluation in glioma cells. Colloids Surf B Biointerfaces. 2018;165:45–55. doi:10.1016/j.colsurfb.2018.02.01629453085
   PubMed Web of Science ®Google Scholar
• Bai F, Diao J, Wang Y, et al. A new water-soluble nanomicelle formed through self-assembly of pectin–curcumin conjugates: preparation, characterization, and anticancer activity evaluation. J Agric Food Chem. 2017;65(32):6840–6847. doi:10.1021/acs.jafc.7b0225028721737
   PubMedGoogle Scholar
• Gelderblom H, Verweij J, Nooter K, Sparreboom A. Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. Eur J Cancer. 2001;37(13):1590–1598. doi:10.1016/S0959-8049(01)00171-X11527683
   PubMed Web of Science ®Google Scholar
• Chaharband F, Kamalinia G, Atyabi F, Mortazavi SA, Mirzaie ZH, Dinarvand R. Formulation and in vitro evaluation of curcumin-lactoferrin conjugated nanostructures for cancerous cells. Artif Cells Nanomed Biotechnol. 2018;46(3):626–636. doi:10.1080/21691401.2017.1337020
   PubMed Web of Science ®Google Scholar
• López-Lázaro M. Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent. Mol Nutr Food Res. 2008;52(S1):S103–S127. doi:10.1002/mnfr.20070023818496811
   PubMed Web of Science ®Google Scholar
• Choi YH, Han DH, Kim S, et al. A randomized, double‐blind, placebo‐controlled trial to evaluate the role of curcumin in prostate cancer patients with intermittent androgen deprivation. Prostate. 2019;79(6):614–621. doi:10.1002/pros.2376630671976
   PubMed Web of Science ®Google Scholar
• Lv K-J, Chen T-C, Wang G-H, Yao Y-N, Yao H. Clinical safety and efficacy of curcumin use for oral lichen planus: a systematic review. J Dermatolog Treat. 2018;1–7. doi:10.1080/09546634.2018.1543849
   Web of Science ®Google Scholar
• Szekalska M, Puciłowska A, Szymańska E, Ciosek P, Winnicka K. Alginate: current use and future perspectives in pharmaceutical and biomedical applications. Int J Polym Sci. 2016;2016:1–17. doi:10.1155/2016/7697031
   Web of Science ®Google Scholar
• Sachan NK, Pushkar S, Jha A, Bhattcharya A. Sodium alginate: the wonder polymer for controlled drug delivery. J Pharm Res. 2009;2(8):1191–1199.
   Google Scholar
• Storka A, Vcelar B, Klickovic U, et al. Safety, tolerability and pharmacokinetics of liposomal curcumin in healthy humans. Int J Clin Pharmacol Ther. 2015;53(1):54–65. doi:10.5414/CP20207625500488
   PubMed Web of Science ®Google Scholar
• Dattani JJ, Rajput DK, Moid N, Highland HN, George LB, Desai KR. Ameliorative effect of curcumin on hepatotoxicity induced by chloroquine phosphate. Environ Toxicol Pharmacol. 2010;30(2):103–109. doi:10.1016/j.etap.2010.04.00121787638
   PubMedGoogle Scholar
• Serairi Beji R, Ben Mansour R, Bettaieb Rebey I, et al. Does Curcuma longa root powder have an effect against CCl4-induced hepatotoxicity in rats: a protective and curative approach. Food Sci Biotechnol. 2019;28(1):181–189. doi:10.1007/s10068-018-0449-330815309
   PubMedGoogle Scholar
• Alharbi B, Fadda L, Ali HM. Evaluation of the renoprotective effect of nano turmeric against toxic dose of copper sulfate: role of vascular cell adhesion molecule-1, kidney injury molecule-1, and signal transducer and activator of transcription 3 protein expressions. J Biochem Mol Toxicol. 2019;33(2):e22243. doi:10.1002/jbt.2224330431687
   PubMedGoogle Scholar
• Edrees NE, Galal AAA, Abdel Monaem AR, Beheiry RR, Metwally MMM. Curcumin alleviates colistin-induced nephrotoxicity and neurotoxicity in rats via attenuation of oxidative stress, inflammation and apoptosis. Chem Biol Interact. 2018;294:56–64. doi:10.1016/j.cbi.2018.08.01230138604
   PubMed Web of Science ®Google Scholar
• Ahsan H, Hadi SM. Strand scission in DNA induced by curcumin in the presence of Cu(II). Cancer Lett. 1998;124(1):23–30. doi:10.1016/s0304-3835(97)00442-49500187
   PubMed Web of Science ®Google Scholar
• Blasiak J, Trzeciak A, Kowalik J. Curcumin damages DNA in human gastric mucosa cells and lymphocytes. J Environ Pathol Toxicol Oncol. 1999;18(4):271–276.15281237
   PubMedGoogle Scholar
• Martín-Cordero C, López-Lázaro M, Gálvez M, Jesús Ayuso M. Curcumin as a DNA topoisomerase II poison. J Enzyme Inhib Med Chem. 2003;18(6):505–509. doi:10.1080/1475636031000161308515008515
   PubMed Web of Science ®Google Scholar
• Aggarwal BB, Harikumar KB. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int J Biochem Cell Biol. 2009;41(1):40–59. doi:10.1016/j.biocel.2008.06.01018662800
   PubMed Web of Science ®Google Scholar
• Holt PR, Katz S, Kirshoff R. Curcumin therapy in inflammatory bowel disease: a pilot study. Dig Dis Sci. 2005;50(11):2191–2193. doi:10.1007/s10620-005-3032-816240238
   PubMed Web of Science ®Google Scholar
• Jian Y-T, Mai G-F, Wang J-D, Zhang Y-L, Luo R-C, Fang Y-X. Preventive and therapeutic effects of NF-kappaB inhibitor curcumin in rats colitis induced by trinitrobenzene sulfonic acid. World J Gastroenterol. 2005;11(12):1747–1752. doi:10.3748/wjg.v11.i12.174715793857
   PubMedGoogle Scholar
• Billerey-Larmonier C, Uno JK, Larmonier N, et al. Protective effects of dietary curcumin in mouse model of chemically induced colitis are strain dependent. Inflamm Bowel Dis. 2008;14(6):780–793. doi:10.1002/ibd.2034818200517
   PubMedGoogle Scholar
• Deguchi Y, Andoh A, Inatomi O, et al. Curcumin prevents the development of dextran sulfate Sodium (DSS)-induced experimental colitis. Dig Dis Sci. 2007;52(11):2993–2998. doi:10.1007/s10620-006-9138-917429738
   PubMed Web of Science ®Google Scholar
• Funk JL, Oyarzo JN, Frye JB, et al. Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis. J Nat Prod. 2006;69(3):351–355. doi:10.1021/np050327j16562833
   PubMed Web of Science ®Google Scholar
• Geisel J, Bruck J, Glocova I, et al. Sulforaphane protects from T cell-mediated autoimmune disease by inhibition of IL-23 and IL-12 in dendritic cells. J Immunol. 2014;192(8):3530–3539. doi:10.4049/jimmunol.130055624639357
   PubMed Web of Science ®Google Scholar
• Xie L, Li X-K, Funeshima-Fuji N, et al. Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production. Int Immunopharmacol. 2009;9(5):575–581. doi:10.1016/j.intimp.2009.01.02519539560
   PubMed Web of Science ®Google Scholar
• Brück J, Holstein J, Glocova I, et al. Nutritional control of IL-23/Th17-mediated autoimmune disease through HO-1/STAT3 activation. Sci Rep. 2017;7(1):44482. doi:10.1038/srep4448228290522
   PubMedGoogle Scholar
• Dolati S, Ahmadi M, Rikhtegar R, et al. Changes in Th17 cells function after nanocurcumin use to treat multiple sclerosis. Int Immunopharmacol. 2018;61:74–81. doi:10.1016/j.intimp.2018.05.01829852475
   PubMed Web of Science ®Google Scholar
• Wang K, Guo C, Dong X, et al. In vivo evaluation of reduction-responsive alendronate-hyaluronan-curcumin polymer-drug conjugates for targeted therapy of bone metastatic breast cancer. Mol Pharm. 2018;15(7):2764–2769. doi:10.1021/acs.molpharmaceut.8b0026629792799
   PubMed Web of Science ®Google Scholar
• Aravind SR, Krishnan LK. Curcumin-albumin conjugates as an effective anti-cancer agent with immunomodulatory properties. Int Immunopharmacol. 2016;34:78–85. doi:10.1016/J.INTIMP.2016.02.01026927614
   PubMed Web of Science ®Google Scholar
• Hong Y, Che S, Hui B, et al. Lung cancer therapy using doxorubicin and curcumin combination: targeted prodrug based, pH sensitive nanomedicine. Biomed Pharmacother. 2019;112:108614. doi:10.1016/J.BIOPHA.2019.10861430798129
   PubMed Web of Science ®Google Scholar
• Kesharwani SS, Kaur S, Tummala H, Sangamwar AT. Overcoming multiple drug resistance in cancer using polymeric micelles. Expert Opin Drug Deliv. 2018;15(11):1127–1142. doi:10.1080/17425247.2018.153726130324813
   PubMed Web of Science ®Google Scholar
• Halder RC, Almasi A, Sagong B, Leung J, Jewett A, Fiala M. Curcuminoids and ω-3 fatty acids with anti-oxidants potentiate cytotoxicity of natural killer cells against pancreatic ductal adenocarcinoma cells and inhibit interferon γ production. Front Physiol. 2015;6. doi:10.3389/fphys.2015.00129.
   PubMed Web of Science ®Google Scholar
• Fiala M. Curcumin and omega-3 fatty acids enhance NK cell-induced apoptosis of pancreatic cancer cells but curcumin inhibits interferon-γ production: benefits of omega-3 with curcumin against cancer. Molecules. 2015;20(2):3020–3026. doi:10.3390/molecules2002302025685909
   PubMed Web of Science ®Google Scholar
• Bhattacharyya S, Md Sakib Hossain D, Mohanty S, et al. Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts. Cell Mol Immunol. 2010;7(4):306–315. doi:10.1038/cmi.2010.1120305684
   PubMedGoogle Scholar