Low density lipoprotein mimic nanoparticles composed of amphipathic hybrid peptides and lipids for tumor-targeted delivery of paclitaxel

References

• Lacko AG, Nair M, Prokai L, Mcconathy WJ. Prospects and challenges of the development of lipoprotein-based formulations for anti-cancer drugs. Exp Opin Drug Deliv. 2007;4(6):665–675. doi:10.1517/17425247.4.6.665
   PubMed Web of Science ®Google Scholar
• Ng KK, Lovell JF, Zheng G. Lipoprotein inspired nanoparticles for cancer theranostics. Acc Chem Res. 2011;44(10):1105–1113. doi:10.1021/ar200017e21557543
   PubMed Web of Science ®Google Scholar
• Jr AM G, Pownall H, Havel RJ. Introduction to the plasma lipoproteins. Methods Enzymol. 1986;128:3–40.3523141
   PubMed Web of Science ®Google Scholar
• Kuzu OF. The role of cholesterol in cancer. Cancer Res. 2016;76(8):1–8. doi:10.1158/0008-5472.CAN-16-0584
   Web of Science ®Google Scholar
• Corbin IR, Li H, Chen J, et al. Low-density lipoprotein nanoparticles as magnetic resonance imaging contrast agents. Neoplasia. 2006;8(6):488–498. doi:10.1593/neo.0583516820095
   PubMed Web of Science ®Google Scholar
• Firestone RA. Low-density lipoprotein as a vehicle for targeting antitumor compounds to cancer cells. Bioconjugate Chem. 1994;5:105–113. doi:10.1021/bc00026a002
   PubMed Web of Science ®Google Scholar
• Rensen PCN, Vrueh RLAD, Kuiper J, Bijsterbosch MK, Biessen EAL, Berkel TJCV. Recombinant lipoproteins: lipoprotein-like lipid particles for drug targeting. Adv Drug Deliv Rev. 2014;7(2):251–276.
   Google Scholar
• Lundberg B. Preparation of drug–low density lipoprotein complexes for delivery of antitumoral drugs via the low density lipoprotein pathway. Cancer Res. 1987;47:4105–4108.3607752
   PubMed Web of Science ®Google Scholar
• Chu ACY, Tsang SY, Lo EHK, Fung KP. Low density lipoprotein as a targeted carrier for doxorubicin in nude mice bearing human hepatoma HepG2 cells. Life Sci. 2001;70:591–601. doi:10.1016/S0024-3205(01)01441-211811903
   PubMed Web of Science ®Google Scholar
• Kader A, Davis PJ, Kara M, Liu H. Drug targeting using low density lipoprotein (LDL): physicochemical factors affecting drug loading into LDL particles. J Control Release. 1998;55(2–3):231–243.9795069
   PubMed Web of Science ®Google Scholar
• Chen SH, Yang CY, Chen PF, et al. The complete cDNA and amino acid sequence of human apolipoprotein B-100. J Biol Chem. 1986;261(28):12918–12921.3759943
   PubMed Web of Science ®Google Scholar
• Nikanjam M, Blakely EA, Bjornstad KA, Shu X, Budinger TF, Forte TM. Synthetic nano-low density lipoprotein as targeted drug delivery vehicle for glioblastoma multiforme. Int J Pharm. 2007;328(1):86–94. doi:10.1016/j.ijpharm.2006.07.04616959446
   PubMedGoogle Scholar
• Baillie G, Owens M, Halbert GW. A synthetic low density lipoprotein particle capable of supporting U937 proliferation in vitro. J Lipid Res. 2002;43(1):69–73.11792724
   PubMed Web of Science ®Google Scholar
• Nikanjam M, Gibbs AR, Hunt CA, Budinger TF, Forte TM. Synthetic nano-LDL with paclitaxel oleate as a targeted drug delivery vehicle for glioblastoma multiforme. J Control Release. 2007;124(3):163–171. doi:10.1016/j.jconrel.2007.09.00717964677
   PubMedGoogle Scholar
• Chen YH, Yang JT, Martinez HM. Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion. Biochemistry. 1972;11:4120–4131. doi:10.1021/bi00772a0154343790
   PubMed Web of Science ®Google Scholar
• Lee JY, Kim JH, Bae KH, et al. Low-density lipoprotein-mimicking nanoparticles for tumor-targeted theranostic applications. Small. 2015;11(2):222–231. doi:10.1002/smll.20130327725137631
   PubMedGoogle Scholar
• Knott TJ, Pease RJ, Powell LM, et al. Complete protein sequence and identification of structural domains of human apolipoprotein B. Nature. 1986;323(6090):734–738. doi:10.1038/323734a03773997
   PubMed Web of Science ®Google Scholar
• Yang CY, Chen SH, Gianturco SH, et al. Sequence, structure, receptor-binding domains and internal repeats of human apolipoprotein B-100. Nature. 1986;323(6090):738–742. doi:10.1038/323738a03095664
   PubMedGoogle Scholar
• Gordon SM, Pourmousa M, Sampson M, et al. Identification of a novel lipid binding motif in apolipoprotein B by the analysis of hydrophobic cluster domains. BBA-Biomembranes. 2017;1859:135–145. doi:10.1016/j.bbamem.2016.10.01927814978
   PubMedGoogle Scholar
• Du XJ, Wang JL, Liu WW, et al. Regulating the surface poly(ethylene glycol) density of polymeric nanoparticles and evaluating its role in drug delivery in vivo. Biomaterials. 2015;69:1–11. doi:10.1016/j.biomaterials.2015.07.04826275857
   PubMedGoogle Scholar
• Zheng G, Chen J, Li H, Glickson JD. Rerouting lipoprotein nanoparticles to selected alternate receptors for the targeted delivery of cancer diagnostic and therapeutic agents. Proc Natl Acad Sci U S A. 2005;102:17757–17762. doi:10.1073/pnas.050867710216306263
   PubMed Web of Science ®Google Scholar
• Lazzari S, Moscatelli D, Codari F, Salmona M, Morbidelli M, Diomede L. Colloidal stability of polymeric nanoparticles in biological fluids. J Nanopart Res. 2012;14:920–929. doi:10.1007/s11051-012-0920-723162376
   PubMed Web of Science ®Google Scholar
• Lundqvist M, Stigler J, Elia G, Lynch I, Cedervall T, Dawson KA. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc Natl Acad Sci USA. 2008;105:14265–14270. doi:10.1073/pnas.080513510518809927
   PubMed Web of Science ®Google Scholar
• Maruyama K. Intracellular targeting delivery of liposomal drugs to solid tumors based on EPR effects. Adv Drug Deliv Rev. 2011;63(3):161–169. doi:10.1016/j.addr.2010.09.00320869415
   PubMed Web of Science ®Google Scholar
• Zhang P, Huang Y, Liu H, et al. A PEG-Fmoc conjugate as a nanocarrier for paclitaxel. Biomaterials. 2014;35(25):7146–7156. doi:10.1016/j.biomaterials.2014.01.02624856103
   PubMed Web of Science ®Google Scholar
• Lee J, Lee SC, Acharya G, Chang CJ, Park K. Hydrotropic solubilization of paclitaxel: analysis of chemical structures for hydrotropic property. Pharm Res. 2003;20(7):1022–1030. doi:10.1023/A:102445820603212880288
   PubMedGoogle Scholar
• Lu Y, Low PS. Folate-mediated delivery of macromolecular anticancer therapeutic agents. Adv Drug Deliv Rev. 2012;64(supp_S):342–352. doi:10.1016/j.addr.2012.09.020
   Google Scholar
• Chen Y, Tezcan O, Li D, et al. Overcoming multidrug resistance using folate receptor-targeted and pH-responsive polymeric nanogels containing covalently entrapped doxorubicin. Nanoscale. 2017;9(29):10404–10419. doi:10.1039/C7NR03592F28702658
   PubMed Web of Science ®Google Scholar
• Jiang LQ, Wang TY, Wang Y, et al. Co-disposition of chitosan nanoparticles by multi types of hepatic cells and their subsequent biological elimination: the mechanism and kinetic studies at the cellular and animal levels. Int J Nanomed. 2019;14:6035–6060. doi:10.2147/IJN.S208496
   PubMed Web of Science ®Google Scholar
• Koltover I, Salditt T, Radler JO, Safinya CR. An inverted hexagonal phase of cationic liposome–DNA complexes related to DNA release and delivery. Science. 1998;281:78–81. doi:10.1126/science.281.5373.789651248
   PubMed Web of Science ®Google Scholar
• Hafez IM, Cullis PR. Roles of lipid polymorphism in intracellular delivery. Adv Drug Deliv Rev. 2001;47:139–148. doi:10.1016/S0169-409X(01)00103-X11311989
   PubMed Web of Science ®Google Scholar
• Suen WLL, Chau Y. Size-dependent internalisation of folate-decorated nanoparticles via the pathways of clathrin and caveolae-mediated endocytosis in ARPE-19 cells. J Pharm Pharmacol. 2014;66(4):564–573. doi:10.1111/jphp.1213424635558
   PubMed Web of Science ®Google Scholar
• Dalal C, Saha A, Jana NR. Nanoparticle multivalency directed shifting of cellular uptake mechanism. J Phys Chem C. 2016;120(12):6778–6786. doi:10.1021/acs.jpcc.5b11059
   Web of Science ®Google Scholar